Advances in contraception : the official journal of the Society for the Advancement of Contraception最新文献_第4页

Endometrial histology in long-term users of the once-a-month injectable contraceptive Cyclofem. 长期使用每月一次注射避孕药Cyclofem的子宫内膜组织学。

Advances in contraception : the official journal of the Society for the Advancement of Contraception Pub Date : 1999-01-01 DOI: 10.1023/a:1006621809825

L Bahamondes, E Maradiegue, J Diaz, J Trelles, C Escanhoela, C Petta, X E Arce

{"title":"Endometrial histology in long-term users of the once-a-month injectable contraceptive Cyclofem.","authors":"L Bahamondes, E Maradiegue, J Diaz, J Trelles, C Escanhoela, C Petta, X E Arce","doi":"10.1023/a:1006621809825","DOIUrl":"https://doi.org/10.1023/a:1006621809825","url":null,"abstract":"This study evaluated endometrial histology in women using the once-a-month injectable contraceptive Cyclofem for one year or more. The study received IRB approval. Seventeen Cyclofem users accepted to be submitted to an endometrial biopsy. All the samples were collected with an endometrial suction curette (Z-Sampler, ZSI Gynecological Product, Chasworth, CA, USA) in an outpatient clinic, 27-33 days after the last injection. The material was fixed immediately in Bouin solution prior to wax embedding and screened as a routine histological examination by a senior pathologist. The pathologist did not know the bleeding status of each woman or the number of injections each woman had received before the biopsy. All women recorded bleeding and spotting for the last 60 days prior to the biopsy. The mean age of volunteers was 25.9 years (range 21-32) and the mean number of injections received was 24.8 (range 14-47). The results were: 4 out of 17 biopsies were found to be inadequate for diagnosis because they consisted of only blood and mucus. Two of these women were bleeding regularly and the other 2 had amenorrhea. Eight endometrial samples presented a proliferative pattern and, in this group, 3 women had amenorrhea and 5 were bleeding regularly. The other 5 biopsies were reported as secretory endometrium, and 4 of them showed pseudodecidual reaction compatible with the administration of progestin. All of these women were bleeding regularly. The results of the biopsies were not related to the number of injections received nor to the age of the women. In conclusion, long-term administration of the injectable contraceptive Cyclofem did not produce adverse alterations in the endometrium as hyperplasia.","PeriodicalId":76977,"journal":{"name":"Advances in contraception : the official journal of the Society for the Advancement of Contraception","volume":"15 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006621809825","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21641204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Safety of intrauterine device insertion by trained nurse-midwives in the Sudan. 苏丹训练有素的护士-助产士的宫内节育器插入安全性。

Advances in contraception : the official journal of the Society for the Advancement of Contraception Pub Date : 1999-01-01 DOI: 10.1023/a:1006675226663

F A Aziz, A A Osman

引用次数: 11

Initial UK experience of the levonorgestrel-releasing contraceptive intravaginal ring. 最初的英国经验左炔诺孕酮释放避孕阴道内环。

Advances in contraception : the official journal of the Society for the Advancement of Contraception Pub Date : 1999-01-01 DOI: 10.1023/a:1006748626008

J Sahota, P M Barnes, E Mansfield, J L Bradley, R J Kirkman

{"title":"Initial UK experience of the levonorgestrel-releasing contraceptive intravaginal ring.","authors":"J Sahota, P M Barnes, E Mansfield, J L Bradley, R J Kirkman","doi":"10.1023/a:1006748626008","DOIUrl":"https://doi.org/10.1023/a:1006748626008","url":null,"abstract":"A study was performed to establish the tolerance, acceptability and associated efficacy of a levonorgestrel-releasing intravaginal ring (IVR) in a sample of British women requiring contraception. This was achieved with an open non-randomized prospective study of 1710 women aged 18-40 years, recruited in 75 centers geographically spread around the UK using an IVR designed to release 20 microg/day of levonorgestrel. Assessments were made at baseline, after 6 weeks, after 3 months and then 3-monthly. After initial insertion of the IVR, it was changed at 3-monthly intervals. A total of 1591 women were eligible for analysis, with 572 available after 12 months and 34 after 24 months of use. Life-table analysis revealed pregnancy rates of 5.1% and 6.5% at 12 months and 24 months, respectively. The IVR was rated as acceptable or very acceptable as a form of contraceptive by 60.7% of women at 12 months. The most common adverse events were menstrual disturbance, headache and vaginal discharge. No significant pattern of biochemical, hematological, microbiological or cytological abnormalities was found but vaginal erythematous lesions were noted at some centers. This IVR was found to be a generally well-accepted method of contraception with a failure rate comparable to some other progestogenonly methods. On this basis, further development of hormone-releasing intravaginal rings is justified.","PeriodicalId":76977,"journal":{"name":"Advances in contraception : the official journal of the Society for the Advancement of Contraception","volume":"15 4","pages":"313-24"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006748626008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21965499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Fine structure of the langur monkey vas deferens and possible role of changes following vasectomy in the success or failure of the vasovasostomy. 叶猴输精管的精细结构及其输精管切除术后改变在输精管吻合术成功或失败中的可能作用。

Advances in contraception : the official journal of the Society for the Advancement of Contraception Pub Date : 1999-01-01 DOI: 10.1023/a:1006704827825

N K Lohiya, S Srivastava, A S Ansari, B Manivannan

{"title":"Fine structure of the langur monkey vas deferens and possible role of changes following vasectomy in the success or failure of the vasovasostomy.","authors":"N K Lohiya, S Srivastava, A S Ansari, B Manivannan","doi":"10.1023/a:1006704827825","DOIUrl":"https://doi.org/10.1023/a:1006704827825","url":null,"abstract":"Studies on the ultrastructure of the vas deferens have been carried out in control, vasectomized (6 and 24 months) and vasovasostomized (12 months) langur monkeys (Presbytis entellus entellus Dufresne). Vas deferens epithelium of the control animals depicted four types of cells, viz. the basal cells, principal cells, mitochondria-rich or apical cells and pencil or dark cells. The basal cells were short, cuboidal in nature with prominent nuclei, and contained sparse cytoplasmic organelles. The principal cells were characterized by the presence of nuclei with irregular outline and intranuclear electron-dense granules, well-developed Golgi bodies with prominent secretory vesicles, cisternae of rough endoplasmic reticulum, mitochondria, free ribosome particles, lysosomes and stereocilia in the cytoplasm, suggesting an active secretory role, as well as the absorptive functions of the cells. The mitochondria-rich cells consisted of numerous mitochondria, and other cytoplasmic organelles were sparse. The pencil cells were dark, slightly compressed and situated between the principal cells. Vasectomy resulted in reduction of cytoplasmic volume and vacuolization of the cytoplasm, especially in the Golgi region of the principal cells. Rough endoplasmic reticulum and mitochondria were poorly defined. Vasovasostomy showed no appreciable improvement in the configuration of the cytoplasmic organelles. The results suggest that a persistent reduced secretory activity of the cells following vasectomy and vasovasostomy might also be one of the factors responsible for unsuccessful vasovasostomy.","PeriodicalId":76977,"journal":{"name":"Advances in contraception : the official journal of the Society for the Advancement of Contraception","volume":"15 4","pages":"337-50"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006704827825","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21967348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A decade of experience with TCu200. TCu200的十年经验。

Advances in contraception : the official journal of the Society for the Advancement of Contraception Pub Date : 1999-01-01 DOI: 10.1023/a:1006708911895

H P Bhattoa, S Ganacharya, I Batár

引用次数: 3

Contraceptive methods used and preferred by men and women. 男性和女性使用和首选的避孕方法。

Advances in contraception : the official journal of the Society for the Advancement of Contraception Pub Date : 1999-01-01 DOI: 10.1023/a:1006760928734

A L Kirkkola, I Virjo, M Isokoski, K Mattila

引用次数: 10

Contraceptive status and sexual behavior in women over 35 years of age in India. 印度35岁以上妇女的避孕状况和性行为。

Advances in contraception : the official journal of the Society for the Advancement of Contraception Pub Date : 1999-01-01 DOI: 10.1023/a:1006705718070

N Agarwal, D Deka, D Takkar

{"title":"Contraceptive status and sexual behavior in women over 35 years of age in India.","authors":"N Agarwal, D Deka, D Takkar","doi":"10.1023/a:1006705718070","DOIUrl":"https://doi.org/10.1023/a:1006705718070","url":null,"abstract":"The aim of this paper is to survey the current contraception use and analyze the sexual patterns in women above 35 years of age in India. Five hundred women, of whom 250 were at least 35 years old and 250 were less than 35 years old (control group) were interviewed with the help of a prepared questionnaire. A permanent surgical method of contraception had been accepted by 40.4% of women > or = 35 years old versus 16.8% of women < 35 years old. Of various temporary methods, an intrauterine device (IUD) was used by 5.2% and 22.8% oral contraceptive pills (OCs) by 1.2% and 9.6%, and natural methods by 6.4% and 3.2%, in women > or = 35 years and < 35 years, respectively. No contraception was used by 25.6% women > or = 35 years. A history of medical termination was given by 67.18% of non-contraceptive users vs. 27.41% of contraceptive users in women > or = 35 years. Coital frequency was noted at 4.32 times/month in women > or = 35 years but 7.2 times/month in women <35 years. Among contraceptive users > or = 35 years, coital frequency was 4.9 times/month compared with 3.9 times/month in non-contraceptive users. There is a high acceptance of irreversible sterilization and a high abortion rate in women > or = 35 years. Use of contraceptives was linked with increased sexual activity and a decreased abortion rate.","PeriodicalId":76977,"journal":{"name":"Advances in contraception : the official journal of the Society for the Advancement of Contraception","volume":"15 3","pages":"235-44"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006705718070","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21852773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Title Index to Volume 15 第15卷的标题索引

Advances in contraception : the official journal of the Society for the Advancement of Contraception Pub Date : 1999-01-01 DOI: 10.1023/A:1017369230551

引用次数: 0

Reversible azoospermia by oral administration of the benzene chromatographic fraction of the chloroform extract of the seeds of Carica papaya in rabbits. 口服番木瓜种子氯仿提取物的苯色谱组分对家兔可逆性无精子症的影响。

Advances in contraception : the official journal of the Society for the Advancement of Contraception Pub Date : 1999-01-01 DOI: 10.1023/a:1006701826831

N K Lohiya, P K Mishra, N Pathak, B Manivannan, S C Jain

{"title":"Reversible azoospermia by oral administration of the benzene chromatographic fraction of the chloroform extract of the seeds of Carica papaya in rabbits.","authors":"N K Lohiya, P K Mishra, N Pathak, B Manivannan, S C Jain","doi":"10.1023/a:1006701826831","DOIUrl":"https://doi.org/10.1023/a:1006701826831","url":null,"abstract":"Contraceptive efficacy, reversibility and toxicity, if any, of the benzene, chloroform and ethyl acetate chromatographic fractions of the chloroform extract of the seeds of Carica papaya have been investigated in adult male rabbits at a dose regimen of 50 mg/animal/day for 150 days of treatment. Body weight, semen analysis, hematology, serum clinical biochemistry and the fertility status of control and treated animals were evaluated. Chloroform and ethyl acetate chromatographic fractions did not produce appreciable changes in these parameters. However, the benzene chromatographic fraction resulted in uniform azoospermia after 15 days of treatment, which was maintained for the remainder of the 150-day observation period. The levels of fructose, glycerophosphocholine, acid phosphatase and lactate dehydrogenase in the seminal plasma were within the control range. Hematology and the serum clinical parameters showed no appreciable changes, indicating lack of toxicity. The libido of the treated animals was normal and the fertility rate was zero. Complete normalcy of altered parameters was observed 60 days following withdrawal of treatment. It is concluded that the benzene chromatographic fraction of the chloroform extract of the seeds of Carica papaya possesses reversible male contraceptive potential and the effects appear to be mediated through the testis.","PeriodicalId":76977,"journal":{"name":"Advances in contraception : the official journal of the Society for the Advancement of Contraception","volume":"15 2","pages":"141-61"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006701826831","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21830563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 40

Quinacrine sterilization: experience among women at high risk for surgery. 奎宁绝育:手术高危妇女的经验。

Advances in contraception : the official journal of the Society for the Advancement of Contraception Pub Date : 1999-01-01 DOI: 10.1023/a:1006757914435

A R Sarin

{"title":"Quinacrine sterilization: experience among women at high risk for surgery.","authors":"A R Sarin","doi":"10.1023/a:1006757914435","DOIUrl":"https://doi.org/10.1023/a:1006757914435","url":null,"abstract":"A non-surgical method of female sterilization is needed because many women are at high risk of complications with standard surgical methods, especially in developing countries. Also, some women who desire sterilization refuse it for fear of surgery. To meet these special needs, we initiated a trial of quinacrine sterilization (QS), a non-surgical method involving transcervical insertion of 252 mg quinacrine as pellets by a modified IUD inserter. Diclofenac (50 mg) was inserted with the quinacrine pellets. This insertion was repeated a month later and a 150-mg injection of depo medroxyprogesterone was administered at the time of the first insertion. One hundred and thirty-four women of reproductive age entered the trial. Of these, 92 were considered to be at high risk for surgery, 27 had refused surgery, and 15 had had failed surgical sterilization. Mean follow-up was 3.46 years. No pregnancies or serious complications were experienced. The main side-effect was menstrual irregularity, due probably to the depo medroxyprogesterone injection. QS is a suitable option for women at high risk of surgical complications.","PeriodicalId":76977,"journal":{"name":"Advances in contraception : the official journal of the Society for the Advancement of Contraception","volume":"15 3","pages":"175-8"},"PeriodicalIF":0.0,"publicationDate":"1999-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1006757914435","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21851550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15