{"title":"[Organ specific MRI contrast media in general practice].","authors":"W Schima","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Conventional MR imaging with non-specific gadolinium contrast agents is useful in the detection and staging of malignancies. With the development of organ-specific MR contrast agents, MR imaging is assuming an even larger role in body imaging. Two different classes of liver-specific agents, hepato-biliary agents targeted to the hepatocytes, and reticulo-endothelial agents (or Kupffer cell agents) targeted to the reticuloendothelial system in the liver and spleen, have been developed. MRI with liver-specific contrast agents is superior to helical CT for detection of liver metastases. Mangafodipir, which was originally developed as a liver-specific agent, has been shown to accumulate in the pancreas as well. Recent studies have revealed that mangafodipir-enhanced MRI is at least equal to spiral CT in the staging of pancreatic cancer and may be superior to CT in the detection of small cancers. Blood-pool contrast agents with a long blood half-life, such as ultrasmall iron oxide particles (USPIO), have been developed for MR angiography. After the clearance from the vascular system, USPIO are taken up by phagocytes and accumulate in normal lymph, but not in metastatic nodes. This effect can be exploited to increase the accuracy of MRI in lymph node staging of cancer of head-neck, lung or pelvis. In conclusion, various organ-specific MR contrast agents with a wide range of clinical applications have been developed. Future studies will demonstrate the role of contrast-enhanced MRI in comparison with multi-detector array CT.</p>","PeriodicalId":76823,"journal":{"name":"Wiener medizinische Wochenschrift. Supplement","volume":" 113","pages":"8-11"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22276180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A M Herneth, M Dominkus, A Kurtaran, Susanna Lang, T Rand, F Kainberger
{"title":"[Bone metastases: new trends in diagnostic imaging].","authors":"A M Herneth, M Dominkus, A Kurtaran, Susanna Lang, T Rand, F Kainberger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Skeletal metastases are common in patients with cancers of the breast, lung, kidneys, prostate, and thyroid gland. Two main aspects have to be considered in diagnostic imaging. Screening in patients with known primary tumor. Triphasic Sczintigraphy is the imaging modality of choice for this purpose, however, whole-body-magnetic resonance imaging seems to be a potential alternative. Evaluation of suspicious skeletal lesions, which is currently dominated by magnetic resonance imaging. New perspectives for preoperative staging as well as for reconstruction- and implant-surgery are made available by multidetector-row-computed tomography. Non-invasive techniques, such as diffusion weighted imaging, positron emission tomography and positron emission tomography/computed tomography are now available, which seem to have potential for reliable tissue characterization. This feature is critical for monitoring treatment response in oncology.</p>","PeriodicalId":76823,"journal":{"name":"Wiener medizinische Wochenschrift. Supplement","volume":" 113","pages":"92-4"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22276717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Value of roentgen diagnosis in recognition of primary and potentially malignant bone tumors].","authors":"Christina Müller, F Kainberger, H Imhof","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To assess the efficiency of plain radiographs for the detection of primary and potentially malignant bone tumors a retrospective study in 70 patients with histologically proven bone sarcomas was performed. Plain radiographs were the first imaging modality in most cases and for many patients the basic step leading to further diagnostic investigations. With young patients suffering from bone pain imaging work-up was obtained immediately, whereas older patients showed significant delay until radiographs were performed. The findings of this study suggest that radiography is an effective tool for the diagnosis of primary and potentially malignant bone tumors and that physicians should think of bone tumors also when patients beyond the adolescence have focal bone pain.</p>","PeriodicalId":76823,"journal":{"name":"Wiener medizinische Wochenschrift. Supplement","volume":" 113","pages":"95-6"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22276718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brigitte Happel, M Breitenseher, S Trattnig, Ch Gäbler, Ch Kukla, Th Rand, H Imhof, G Lechner
{"title":"[Middle field and low field magnetic resonance tomography in wrist injuries].","authors":"Brigitte Happel, M Breitenseher, S Trattnig, Ch Gäbler, Ch Kukla, Th Rand, H Imhof, G Lechner","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the diagnostic value of magnet resonance imaging in comparison of a dedicated 0.2-T unit and a 1.0-T unit in patients with clinically suspected scaphoid fractures and other wrist fractures.</p><p><strong>Material and methods: </strong>In 20 patients (14 m/6 f) with clinically suspected scaphoid fractures and a normal six view radiographic exam, magnet resonance imaging was performed first with the dedicated 1.0-T unit and afterwards with the 0.2-T unit within 7 days after trauma. T1 weighted spin-echo, STIR and T2-weighted 3D GRE sequences were performed.</p><p><strong>Results: </strong>The 0.2 Tesla dedicated system is inferior to the 1.0 Tesla unit concerning the outcome of the 3 examiners. Especially the areas of bone bruise showed different results: each examiner detected at least two more cases of bone bruise with the 1.0 Telsa unit, which could not be defined with the 0.2 Tesla unit.</p><p><strong>Conclusions: </strong>This study shows, how utmost sensitive magnet resonance imaging is referring to unremoved fractures of the scaphoid and to other wrist abnormalities. Results with the 0.2 Tesla dedicated system was inferior compared to the 1.0 Tesla unit.</p>","PeriodicalId":76823,"journal":{"name":"Wiener medizinische Wochenschrift. Supplement","volume":" 113","pages":"41-2"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22276790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Trends in Vienna radiology--from roentgen laboratory to university clinic for radiodiagnosis].","authors":"G Lechner, F Kainberger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In Vienna/Austria, with leading representatives of the so-called second Viennese medical school at the turn of the 19th to the 20th century, the detection of x-rays by W. C. Röntgen was observed with special interest. In the general hospital of Vienna, where still today the medical school of the university of Vienna is hosted, high research activities to understand the origin and the effects of X-rays were performed. Guido Holzknecht (1872-1931) was the first chairman of the central roentgen laboratory. Today, the scientific and the clinical activities at the department of diagnostic radiology are manifold and virtually all fields of imaging are covered.</p>","PeriodicalId":76823,"journal":{"name":"Wiener medizinische Wochenschrift. Supplement","volume":" 113","pages":"4-7"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22275113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Radiologic progression of rheumatoid arthritis in early basic drug therapy].","authors":"M Wick, F Kainberger, J S Smolen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>For therapy and follow-up control in early disease modifying antirheumatic drug (DMARD) treated rheumatoid arthritis (RA), objective quantification is still lacking. Therefore, radiological analyses are considered the most appropriate method. One aim of this study was to retrospectively determine the time-dependent progression of joint damage in RA patients on DMARDs. Outpatient records and radiographs from hands and feet of 54 RA patients on DMARDs were evaluated. Radiographs were quantified by using the original Larsen score and a newly developed computer-assisted quantification software. Our observations showed that radiologically-detectable damage in all patients, regardless of their treatment, is most pronounced during the first year of disease, being mitigated and generally progressing linearly in the subsequent years. Cumulative ESR correlated with RA progression, and its reduction with therapeutic efficacy.</p>","PeriodicalId":76823,"journal":{"name":"Wiener medizinische Wochenschrift. Supplement","volume":" 113","pages":"46-7"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22276792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Important results of about 45 years balneo-medical research in Bad Hall].","authors":"R Winkler, M Klieber","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It was tried to show the most essential results of a approximately 45 years' research activity on the field of iodine balneology from the Paracelsus Institute and--since 1993--from the Paracelsus-Gesellschaft Bad Hall. The papers were concerned with: basical studies about the chemistry of the iodine waters, generation of special analytic methods and techniques for iodine determinations and for investigations of the iodine metabolism, generation of new therapeutical iodine applications (for example: eye iontophoresis, electro-aerosol; preparation of the iodine water for a mineral water indoor swimming-bath and for special therapy solutions), investigation of the (favourable) iodine effects on the cardiac and circulation system, on blood rheology, thyroid function, lipid metabolism and on the antioxidant defence mechanisms (with special consequences for arteriosclerosis, diabetes mellitus and cataract), also on visual function and eye diseases (retina, color perception, contrast sensitiveness, cataract, dry eye) and respiratory diseases. Comparative studies on patients and on experimental animals as well as model experiments (e.g. on connective tissue: in vitro studies; tissue cultures) have been used to objectify many empirically observed cure effects. Possible side-effects of a cure with iodine brine (e.g. iodism) were mentioned.</p>","PeriodicalId":76823,"journal":{"name":"Wiener medizinische Wochenschrift. Supplement","volume":" 110","pages":"3-11"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20561047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Seizures and driver's licence].","authors":"G S Barolin, A Haslinger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Legislation leaves a wide margin of freedom of judgement to the medical expert in the forensic assessment of a person's suitability for holding a driver's license. We have to make use of this freedom very cautiously with regard to social aspects as well as to the presently accepted state of scientific knowledge. In cases of first manifestations of epilepsy we must postulate--as a rule of thumb--a seizure-free period of two years with regular medication and clinical and electro-encephalographic checkups. The (epileptic or non-epileptic) \"accidental seizure\" is characterized by the releasing influence of powerful external noxious factors. In these cases, the patients should be seizure-free for at least six months before driving can be resumed. In all cases, the evaluation depends on the continuous observance of the patients, taking into account any underlying primary illness (alcoholism, cerebral vascular disease, conditions following brain surgery or trauma). The organic brain syndrome is an essential additional factor, together with the feasibility of treatment and the patient's compliance. Evaluation of the clinical picture is of foremost importance, support by EEG-findings, serum levels and psychological tests. Knowledge of cumulative factors, elimination and side-effects of anticonvulsive drugs is essential. According to the present view, medication should be continued over a period of many years. Curative medicine and medical assessment are not mutually exclusive, but require a distinct differentiation in every single case.</p>","PeriodicalId":76823,"journal":{"name":"Wiener medizinische Wochenschrift. Supplement","volume":"109 ","pages":"Suppl 9-19"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13085908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The expertise situation as pathoplastic factor].","authors":"G S Barolin, H Schmid, E Cziudaj","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Underlying attitudes of apprehension or desire have an essential pathoplastic function, especially in the situation of medical assessment. The functionality of symptoms and complaints requires a diagnostic approach which is not oriented simply towards the \"exclusion of organic causes\". Interaction between somatogenic and psychogenic factors is by far more common than sheer functionality. Although widely neglected in our medical teaching and literature, these problems are not confined to the mere assessment of temporary or permanent invalidity, but are of great importance for the entire medical sphere, including manifestations and course of a disease, therapeutic success etc. In Austria, the population of foreign workers is in a special position due to socio-economic preconditions, partly due to short-sighted policy devoid of psycho-hygienic considerations. This situation requires thorough analysis free of emotions, which should lead to the development of sensible, although in some respects belated, measures. The latest economical recession has revealed several faulty courses of development in our system of social and health insurance, which needs revision urgently lest it should collapse. In this respect, the medical profession is called upon to contribute to a necessary curtailment of excessive misuse within a system that has become inflexible during the past decades, thereby endangering the valuable achievements of social medicine.</p>","PeriodicalId":76823,"journal":{"name":"Wiener medizinische Wochenschrift. Supplement","volume":"109 ","pages":"Suppl 20-36"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13085906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The physician as judicial expert witness].","authors":"K Stellamor, J W Steiner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Excellent special knowledge and consideration of the limits of competence in his own special field as well as in the court procedures are characteristic of a medical expert at law court. Only he provides medical expert knowledge that the court lacks in criminal, civil and social law. This must not mislead him to try to solve legal problems, ie to play the role of a \"judge in white\". Therefore knowledge of our jurisdiction is a necessity. Duties and rights of medical experts are discussed. The necessary human conduct with the person concerned is emphasized. The correct way of preparing an expert evidence is discussed in the special case of the causal connection. In conclusion it seems mandatory to include the topic 'medical expert' into the theoretical and practical education of physicians.</p>","PeriodicalId":76823,"journal":{"name":"Wiener medizinische Wochenschrift. Supplement","volume":"109 ","pages":"Suppl 4-8"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13085907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}