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Wiener klinische Wochenschrift. Supplementum最新文献

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Laboratory Medicine in Diagnosis and Treatment. European Society of Clinical Pathology (SEPaC) seminar-congress. Vienna, Austria, May 22-27, 1995. Abstracts. 诊断和治疗中的检验医学。欧洲临床病理学会(SEPaC)研讨会。奥地利维也纳，1995年5月22日至27日。摘要。
Wiener klinische Wochenschrift. Supplementum Pub Date : 1995-01-01
{"title":"Laboratory Medicine in Diagnosis and Treatment. European Society of Clinical Pathology (SEPaC) seminar-congress. Vienna, Austria, May 22-27, 1995. Abstracts.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76822,"journal":{"name":"Wiener klinische Wochenschrift. Supplementum","volume":"199 ","pages":"1-23"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18656870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Days of Intensive Medicine-Transplantation. Wien, 2-4 February 1995. Abstracts]. 《强化医学移植的日子》维也纳，1995年2月2日至4日。摘要]。
Wiener klinische Wochenschrift. Supplementum Pub Date : 1995-01-01
{"title":"[Days of Intensive Medicine-Transplantation. Wien, 2-4 February 1995. Abstracts].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76822,"journal":{"name":"Wiener klinische Wochenschrift. Supplementum","volume":"198 ","pages":"1-39"},"PeriodicalIF":0.0,"publicationDate":"1995-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18629262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Metabolic disturbances and nutrition of the intensive care patient. Vienna, 24-26 February 1994. Abstracts]. [重症监护病人的代谢紊乱与营养。]维也纳，1994年2月24日至26日。摘要]。
Wiener klinische Wochenschrift. Supplementum Pub Date : 1994-01-01
{"title":"[Metabolic disturbances and nutrition of the intensive care patient. Vienna, 24-26 February 1994. Abstracts].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76822,"journal":{"name":"Wiener klinische Wochenschrift. Supplementum","volume":"196 ","pages":"1-41"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18909041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[13th Austrian Geriatrics Congress on Healthy Aging. Bad Hofgastein, 19-25 March 1994. Abstracts]. 第十三届奥地利老年病学健康老龄化大会[j]。Bad Hofgastein, 1994年3月19日至25日。摘要]。
Wiener klinische Wochenschrift. Supplementum Pub Date : 1994-01-01
{"title":"[13th Austrian Geriatrics Congress on Healthy Aging. Bad Hofgastein, 19-25 March 1994. Abstracts].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76822,"journal":{"name":"Wiener klinische Wochenschrift. Supplementum","volume":"197 ","pages":"1-26"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18980406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An evaluation of a non-isotopic homogeneous enzyme immunoassay (CEDIA assay) for cortisol and its clinical utility. 评估非同位素均相酶免疫测定(CEDIA测定)皮质醇及其临床应用。
Wiener klinische Wochenschrift. Supplementum Pub Date : 1992-01-01
M Fleisher, C Eisen, M K Schwartz
{"title":"An evaluation of a non-isotopic homogeneous enzyme immunoassay (CEDIA assay) for cortisol and its clinical utility.","authors":"M Fleisher,&nbsp;C Eisen,&nbsp;M K Schwartz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serum cortisol is one of the more frequently requested steroid hormone assays. Its use is important in evaluating diseases of the adrenal cortex and pituitary. We briefly review the biochemistry of cortisol synthesis, the pathophysiology resulting from adrenal and pituitary abnormalities and the more specific immunochemical procedures which have replaced colorimetric chemical assays for cortisol. We also report our results on the evaluation of the analytical performance of the non-isotopic homogeneous CEDIA Cortisol assay and compare the advantages of this assay to state-of-the-art immunoassays.</p>","PeriodicalId":76822,"journal":{"name":"Wiener klinische Wochenschrift. Supplementum","volume":"191 ","pages":"77-80"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12678402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Results of multicenter evaluation of reagents for determination of sodium, potassium and chloride ions using enzyme activation]. 【酶活化法测定钠、钾、氯离子试剂的多中心评价结果】。
Wiener klinische Wochenschrift. Supplementum Pub Date : 1992-01-01
V Ehrhardt, H Baadenhuijsen, S Brenna, M Browne, L Garcia-Beltrán, K Hellsing, W R Külpmann, K Paschen, C Pascual-Mostaza, P Pei
{"title":"[Results of multicenter evaluation of reagents for determination of sodium, potassium and chloride ions using enzyme activation].","authors":"V Ehrhardt,&nbsp;H Baadenhuijsen,&nbsp;S Brenna,&nbsp;M Browne,&nbsp;L Garcia-Beltrán,&nbsp;K Hellsing,&nbsp;W R Külpmann,&nbsp;K Paschen,&nbsp;C Pascual-Mostaza,&nbsp;P Pei","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We present the results of a multicentre evaluation with Boehringer Mannheim/Hitachi instruments of new \"enzymatic\" methods for the determination of Na+, K+, and Cl- in serum or plasma. The between-day coefficient of variation was less than 1.4% (Na+), less than 2.6% (K+) and less than 1.7% (Cl-). The linear range of the assays were at least 80 to 200 mmol/l (Na+), 1.5 to 17 mmol/l (K+) and about 30 to at least 200 mmol/l (Cl-). The comparisons with routine flame atomic emission spectrometry and coulometry showed a satisfactory agreement of the test results. The \"enzymatic\" assays are insensitive to even grossly elevated levels of bilirubin and lipids (sodium, potassium, and chloride assays), NH4+ (potassium assay) and amylase (chloride assay). Interference by various drugs was not detected. Since the new methods can easily be adapted to photometric clinical chemistry instruments, they represent a valuable alternative to the use of ion-selective electrodes, flame atomic emission spectrometry and coulometry.</p>","PeriodicalId":76822,"journal":{"name":"Wiener klinische Wochenschrift. Supplementum","volume":"192 ","pages":"12-21"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12672061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
["Utstein style" documentation of resuscitation--initial experiences]. [“乌斯坦风格”的复苏记录——最初的经历]。
Wiener klinische Wochenschrift. Supplementum Pub Date : 1992-01-01
F Sterz, H Domanovits, K Janata, I Kürkciyan, V Dufek, C Madl, P Siostrzonek, C Wilschke
{"title":"[\"Utstein style\" documentation of resuscitation--initial experiences].","authors":"F Sterz,&nbsp;H Domanovits,&nbsp;K Janata,&nbsp;I Kürkciyan,&nbsp;V Dufek,&nbsp;C Madl,&nbsp;P Siostrzonek,&nbsp;C Wilschke","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76822,"journal":{"name":"Wiener klinische Wochenschrift. Supplementum","volume":"194 ","pages":"13-4"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12462240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Results of the multicenter evaluation of a homogeneous immunoassay for digitoxin based on the cloned enzyme donor immunoassay technology. 基于克隆酶供体免疫分析技术的地地黄毒素均相免疫分析的多中心评价结果。
Wiener klinische Wochenschrift. Supplementum Pub Date : 1992-01-01
J Jarausch, Y Cano, E Hammer, G Hafner, P Kaspar, H Malandain, L Pokieser, H Wieland, D Willems, M Windisch
{"title":"Results of the multicenter evaluation of a homogeneous immunoassay for digitoxin based on the cloned enzyme donor immunoassay technology.","authors":"J Jarausch,&nbsp;Y Cano,&nbsp;E Hammer,&nbsp;G Hafner,&nbsp;P Kaspar,&nbsp;H Malandain,&nbsp;L Pokieser,&nbsp;H Wieland,&nbsp;D Willems,&nbsp;M Windisch","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We evaluated a CEDIA assay for the determination of digitoxin in serum on random access analyzers. The multicenter evaluation included studies on the analytical range, calibration stability and reproducibility of the new assay. Moreover, recovery in controls, transferability of results obtained in different laboratories, comparability with routine methods, and the effect of various interfering factors have been analyzed. Summarized the analytical performance was comparable to that of routine methods. The CEDIA Digitoxin assay represents an attractive alternative to established digitoxin immunoassays because it can be performed on random access analyzers, thus permitting the simultaneous determination of digitoxin and other serum analytes without sample splitting.</p>","PeriodicalId":76822,"journal":{"name":"Wiener klinische Wochenschrift. Supplementum","volume":"191 ","pages":"73-6"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12678401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CEDIA--homogeneous immunoassays for the 1990s and beyond. CEDIA——20世纪90年代及以后的均质免疫测定。
Wiener klinische Wochenschrift. Supplementum Pub Date : 1992-01-01
W A Coty, R Loor, N Bellet, P L Khanna, P Kaspar, M Baier
{"title":"CEDIA--homogeneous immunoassays for the 1990s and beyond.","authors":"W A Coty,&nbsp;R Loor,&nbsp;N Bellet,&nbsp;P L Khanna,&nbsp;P Kaspar,&nbsp;M Baier","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>New homogeneous enzyme immunoassays have been developed for cortisol, digoxin, digitoxin, theophylline, phenytoin, and phenobarbital using the cloned enzyme donor immunoassay technology. As applied to Boehringer Mannheim/Hitachi analysis systems these methods provide rapid, accurate and precise quantification of analytes, with minimal interferences from endogenous serum constituents and low cross-reactivities to structurally-related hormonal precursors, drug metabolites and natural compounds. Additional significant features of the new assays are linear standard curves and two-point calibration. The six CEDIA assays join the two currently available CEDIA assays for determination of the thyroid parameters T4 and T Uptake. Additional new therapeutic drug and anemia monitoring assays are under development, demonstrating the versatility of the cloned enzyme donor immunoassay technology. These tests, in concert with Boehringer Mannheim/Hitachi analyzers, provide a high throughput, random access immunoassay system. The menu of available assays should continue to increase during the 1990s, providing efficient automation while allowing consolidation of testing on a limited number of instrument systems.</p>","PeriodicalId":76822,"journal":{"name":"Wiener klinische Wochenschrift. Supplementum","volume":"191 ","pages":"5-11"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12678489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the CEDIA digoxin assay on Boehringer Mannheim/Hitachi 717 analyzer. CEDIA地高辛检测在勃林格曼海姆/日立717分析仪上的评价。
Wiener klinische Wochenschrift. Supplementum Pub Date : 1992-01-01
F L Redondo
{"title":"Evaluation of the CEDIA digoxin assay on Boehringer Mannheim/Hitachi 717 analyzer.","authors":"F L Redondo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Some aspects of a new homogeneous enzyme immunoassay for the determination of digoxin have been evaluated, as part of a multicenter project. The CEDIA Digoxin assay is based on the use of two beta-galactosidase fragments (EC 3.2.1.23) produced by recombinant DNA techniques, one of them linked to digoxin. These two fragments couple to form the complete active enzyme, if not hindered by anti-digoxin antibodies. Digoxin in serum competes for antibody binding. The procedure can easily be automated and does not require special equipment. The imprecision of the method was studied at three different concentration levels (0.56, 1.29 and 2.77 ng/mL of digoxin). Within-run coefficients of variation were 8.01%, 5.57% and 3.30%, respectively, the corresponding between-day CVs being 17.4%, 8.41% and 4.89%. The procedure was found to be linear up to 4.4 ng/mL. Reagents were stable for at least four weeks. Results obtained by the CEDIA Digoxin assay compared well with those obtained by fluorescence polarization immunoassay.</p>","PeriodicalId":76822,"journal":{"name":"Wiener klinische Wochenschrift. Supplementum","volume":"191 ","pages":"66-8"},"PeriodicalIF":0.0,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12678492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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