{"title":"[Academician in exile (little-known pages on the life of S.S. Iudin, Academician of the USSR Academy of Sciences)].","authors":"A B Rusakov","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76796,"journal":{"name":"Vestnik Akademii meditsinskikh nauk SSSR","volume":" 2","pages":"62-4"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13204382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E B Sirovskiĭ, V G Amcheslavskiĭ, V P Kulikovskiĭ, V D Tenedieva, S A Lobanov, M E Polonskaia, Iu N Pokid'ko
{"title":"[Mechanisms of development of brain edema in neurosurgical pathology].","authors":"E B Sirovskiĭ, V G Amcheslavskiĭ, V P Kulikovskiĭ, V D Tenedieva, S A Lobanov, M E Polonskaia, Iu N Pokid'ko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>As many as 120 neurosurgical patients were examined after the excision of hemispheric gliomas, basal and subtentorial tumors. Based on an the computer-aided analysis biochemical and clinical data, attempts have been made to unify the mechanisms responsible for brain edema development in patients with neurosurgical pathology. In the early postoperative period, brain edema occurs in 95% of neurosurgical patients. Edema development, spreading and intensity depend on the site and nature of the primary pathological focus as well as on traumatism of surgical interventions. It is proved that edema is an original, biologically expedient brain response to its injury. This response manifests in hyperhydration of all tissues, with the maximum intensity being concentrated in the focus of injury. Specific (neurogenic neurohumoral) and nonspecific (biochemical, autoimmune, mechanical, and so forth) factors of brain edema development may be distinguished. The differences in the neurogenic and neurohumoral mechanisms by which brain edema develops may be accounted for by the topography of the focus of injury. The closer the pathological focus is to the stem and diencephalic structures, the more remarkable the action of neurogenous and neurohumoral factors and the more distinct the tendency toward edema generalization are. At the diencephalic level of injury, damaged are the structures responsible for central regulation of metabolism and trophicity of nerve cells. The neurogenously precipitated diffuse impairment of permeability of the cells entails their hyperhydration, which marks cellular (cytotoxic) edema. The subtentorial process that affects the vasomotor centre of the stem triggers the neurogenic diffuse alterations in the vascular tone, manifesting in an increase of permeability for water and plasma proteins which is characteristic of vasogenic edema.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":76796,"journal":{"name":"Vestnik Akademii meditsinskikh nauk SSSR","volume":" 7","pages":"7-13"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12943655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Various aspects of using minor regulatory peptides in anesthesiology].","authors":"V V Likhvantsev, V I Smirnova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Dalargin is a Soviet synthetic analog of leu-enkephalin. It was used in a complex of anesthesiological protection (in the form of permanent infusion at a rate of 40-55 micrograms/kg/h) in 331 patients who suffered different operations on the heart, lungs and abdominal cavity. Potential mechanisms of the protective action of the drug were studied in experimental surgical distress. It was found advisable that dalargin may be included into combined general anesthesia to maintain intraoperative organ protection, to stabilize vital functions of the patient at the most crucial and traumatic stages of intervention, and to decrease requirements of narcotic analgetics. It is assumed that dalargin may interact with peripheral opiate receptors. The interaction is likely to be viewed as the main mechanism by which the protective properties of the drug are realized.</p>","PeriodicalId":76796,"journal":{"name":"Vestnik Akademii meditsinskikh nauk SSSR","volume":" 7","pages":"17-21"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12943711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The way of life of the population exposed to radiation as a health-forming factor].","authors":"V P Ferents, V A Prilipko","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76796,"journal":{"name":"Vestnik Akademii meditsinskikh nauk SSSR","volume":" 11","pages":"45-6"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12931311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Epidemiological aspects of hemoblastoses].","authors":"A E Prisiazhniuk, V G Bebeshko","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76796,"journal":{"name":"Vestnik Akademii meditsinskikh nauk SSSR","volume":" 11","pages":"39-40"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12998412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B A Frolov, R Ia Poliak, G N Smagin, A A Nikonorov, I Iu Kul'divatov, L K Chetverikova, L I Inozemtseva, V K Filippov, T A Kramskaia, A A Stadnikov
{"title":"[Pathogenetic mechanisms of stress-induced aggravation of experimental influenza and its prevention].","authors":"B A Frolov, R Ia Poliak, G N Smagin, A A Nikonorov, I Iu Kul'divatov, L K Chetverikova, L I Inozemtseva, V K Filippov, T A Kramskaia, A A Stadnikov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It was stated that in stress-induced aggravation of infection realized in transformation of nonlethal patterns of infection into a lethal one there occurred a manifest dysfunction of hypothalamo-hypophyseal-neurosecretory performance (HHNS) featured by a 2-fold decrease in the blood vasopressin and an essential elevation of the hypothalamic one. The phenomenon is being suggestive of a possible blockage in the hormonal discharge into circulation and the limitation of its participation in the development of defensive and compensatory reactions. Identical HHNS dysfunction was noted in the lethal pattern of the infection. The authors formulated the concept of the main pathogenetic points underlying the damage of vegetative regulation centres. Mechanisms of viral and tissue metabolic damage of CNS were revealed. The authors substantiated the advisability and prospective use+ of antioxidants as applied to the prevention of severe course of influenza and its complications in extremely aggravated patterns.</p>","PeriodicalId":76796,"journal":{"name":"Vestnik Akademii meditsinskikh nauk SSSR","volume":" 4","pages":"50-4"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13027305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Immunochemical characteristics of the population structure of antibody-producing cells in experimental influenza].","authors":"A I Dukhin, I I Agafonova, B L Voĭtsekhovskiĭ","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors presented the results of population study of specific IgG-antibody-forming cells (AFC) in the pool of mice splenocytes performed in the time-course of simulated influenza with the help of experimental mathematical approach which permitted making a detailed observation of the functional structure of the population and analysing the changes in the spectrum of the AFC subpopulations in the time-course of viral disease. Mathematical simulation of the main stage of immunopointed identification of AFC on +nitrocellulose filters (NCF) permitted the verification of the ratio between the characteristic features of the spots on the NCF and the number and affinity of cell-secreting IgG antibodies. New data are obtained on the formation of the population of +virus-specific IgG-AFC which are featured by discreteness of the AFC +affinity ++ spectrum, cyclic changes in their activity and shifts in the stages of the AFC subpopulation activity. The authors substantiated the necessity to revise the existing theoretical models of the formation of humoral immune response to viral infections.</p>","PeriodicalId":76796,"journal":{"name":"Vestnik Akademii meditsinskikh nauk SSSR","volume":" 4","pages":"14-8"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13027431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Nonspecific mitogenic factors of Mycoplasma: immunobiological properties].","authors":"A V Pronin, L G Gorina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The readily extractable surface membrane proteins of M. arthritidis and sodium dodecyl sulfate-solubilized membrane components of M. fermentans were found to have the highest mitogenic action on the splenocytes from CBA mice and the least on those from C57BL/6 mice. The M. arthritidis mitogen (MAM) is an antigen-dependent T-cell mitogen that inhibits the specific proliferation of T cells, inducing their non-specific proliferation. Dextran sulfate-induced blockage of lymphocyte proliferation under the action of MAM was stimulated with interleukin-2, which suggests MAM-induced expression of receptors to interleukin-2 onto the surface of lymphocytes. A factor that has the activity of interleukin-1 and stimulates the proliferation of C57BL/6 murine thymocytes with phytohemagglutinin was found to liberate into a culture medium.</p>","PeriodicalId":76796,"journal":{"name":"Vestnik Akademii meditsinskikh nauk SSSR","volume":" 6","pages":"30-4"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13085406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Arthritic pathogenicity of Mycoplasma and Mycoplasma arthritis in humans].","authors":"Iu V Vul'fovich","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The review deals with Mycoplasma-induced arthritis. It provides the author's own results and the data available in the literature, which suggest that \"arthritogenic\" Mycoplasma make an etiological contribution to the development of human rheumatic arthritis. It also discusses some well-known and hypothetic mechanisms responsible for the pathogenesis of Mycoplasma-induced arthritis.</p>","PeriodicalId":76796,"journal":{"name":"Vestnik Akademii meditsinskikh nauk SSSR","volume":" 6","pages":"6-9"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13087574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Hygienic problems of industrial animal husbandry].","authors":"V F Spirin, M A Mironenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Basic unfavourable factors of working conditions in modern livestock enterprises as well as industrial livestock complexes effects on environmental state are formulated. The relationships between the main subsystems such as forage production, livestock breeding proper, agriproduct processing, working and social infrastructures of the ++agro-industrial complex are established. It is shown that general and occupational morbidity in cattle-breeders is conditioned by the character of production processes, the technology of manure collection, storing, processing and utilization. With livestock enterprises, the borders of their adverse effects spreading in the environment, the rated formulae as well as health improvement measures are validated.</p>","PeriodicalId":76796,"journal":{"name":"Vestnik Akademii meditsinskikh nauk SSSR","volume":" 2","pages":"3-5"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12991353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}