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Ukrainskii biokhimicheskii zhurnal (1978)最新文献

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[Antiradical and antioxidant activity of certain membranotropic substances of synthetic and plant origin]. [某些合成和植物来源的膜性物质的抗自由基和抗氧化活性]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-05-01
Iu I Gubskiĭ, N N Iurzhenko, G S Shapoval, V F Gromovaia, A G Goriushko, A I Averkov
{"title":"[Antiradical and antioxidant activity of certain membranotropic substances of synthetic and plant origin].","authors":"Iu I Gubskiĭ,&nbsp;N N Iurzhenko,&nbsp;G S Shapoval,&nbsp;V F Gromovaia,&nbsp;A G Goriushko,&nbsp;A I Averkov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Antiradical and antioxidative activities of dieton, phoridon, niphedipin, phlamicar, mildronat in vitro were studied by spectrophotometer's method with the use of dyfenilpycrilgydrasil and method of pulse voltametry. Also influence of drugs was studied under antioxidative insufficiency (AOI), which had modelled by exclusion of alpha-tocopherol from the animal's ration.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 3","pages":"128-34"},"PeriodicalIF":0.0,"publicationDate":"1998-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Comparative analysis of semiotic shifts, established by LCS of blood plasma from random samples of studied subjects from the zone of the Chernobyl accident, "Ural Radiation Trace", and collaborators from St. Petersburg Institute of Nuclear Physics of the Russian Academy of Sciences]. [符号学转移的比较分析，由LCS从切尔诺贝利事故区随机取样的研究对象血浆中建立，“乌拉尔辐射痕迹”，与俄罗斯科学院圣彼得堡核物理研究所的合作者]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-05-01
K S Ternovoĭ, T N Selezneva, A V Akleev, I A Pashkov, L A Noskin, N V Klopov, V A Noskin, N F Starodub
{"title":"[Comparative analysis of semiotic shifts, established by LCS of blood plasma from random samples of studied subjects from the zone of the Chernobyl accident, \"Ural Radiation Trace\", and collaborators from St. Petersburg Institute of Nuclear Physics of the Russian Academy of Sciences].","authors":"K S Ternovoĭ,&nbsp;T N Selezneva,&nbsp;A V Akleev,&nbsp;I A Pashkov,&nbsp;L A Noskin,&nbsp;N V Klopov,&nbsp;V A Noskin,&nbsp;N F Starodub","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Using the developed \"semiotic\" classifier of laser correlation spectra of blood plasma the authors have carried out the verification of organism states of patients from the zone of Chernobyl accident, \"Ural radiation trace\" and collaborators from Sanct-Petersbourg Institute of Nuclear Physics. An analysis of results obtained using accidental selections which differed as to the character of radiation injury evidences for high informativeness of \"semiotic\" classifier of laser correlation spectra of blood plasma.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 3","pages":"81-5"},"PeriodicalIF":0.0,"publicationDate":"1998-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of electron irradiation on the structure of microsomal membrane proteins]. 电子辐照对微粒体膜蛋白结构的影响
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-05-01
G P Gorbenko, T S Diubko, V D Krupin
{"title":"[Effect of electron irradiation on the structure of microsomal membrane proteins].","authors":"G P Gorbenko,&nbsp;T S Diubko,&nbsp;V D Krupin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Using tryptophan fluorescence quenching by iodide and acrylamide the effect of electrons with the energy 5 Mev on the structure of microsomal membrane proteins has been studied. Conformation of microsomal proteins were found to change upon irradiation.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 3","pages":"109-13"},"PeriodicalIF":0.0,"publicationDate":"1998-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of hyperbaric oxygenation of lipid peroxidation and the antioxidant system in liver of white rats with acute sodium nitrate poisoning]. [急性硝酸钠中毒大鼠肝脏脂质过氧化及抗氧化系统的高压氧作用]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-05-01
L Iu Glebova
{"title":"[Effect of hyperbaric oxygenation of lipid peroxidation and the antioxidant system in liver of white rats with acute sodium nitrate poisoning].","authors":"L Iu Glebova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The experimental study carried out with white rats Wistar trend, which were introduced of sodium nitrate at a rate of 9.6 g/kg of their mass. It follows to the development of considerable activation of lipid peroxidation and depression of antioxidant system in liver. The obtained results permit supposing the significant role of nitric oxide (NO) in liver as a factor resulting in accumulation of peroxidation products. The research has stated that the use hyperbaric oxygenation (HBO) prevents considerable activation of lipid peroxidation and the decrease of antioxidant enzyme (catalase and superoxide dismutase) activity. The results permit supposing that the effect HBO is connected with the decrease of the rate of reduction of nitrate-ions to NO.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 3","pages":"91-5"},"PeriodicalIF":0.0,"publicationDate":"1998-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Physiological and adaptive value of Na+,K+-ATPase isoenzymes]. [Na+，K+- atp酶同工酶的生理和适应价值]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-05-01
A A Kaplia
{"title":"[Physiological and adaptive value of Na+,K+-ATPase isoenzymes].","authors":"A A Kaplia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A current state of the researches related to functional specificity of the Na+, K(+)-ATP-ase isozymes determined by their catalytic properties, individual sensitivity to regulation by hormones and other endogenic substances and to membrane structural disorders has been reviewed to clarify the physiological expediency of the Na+, K(+)-ATP-ase isoforms. The data on isozymes expression in brain in the ontogenesis, their individual sensitivity to ouabain and peculiarities of the membrane properties are considered. The adaptive significance of the Na+, K(+)-ATP-ase isozymes in expansion of tissue compensatory resources at some physiological and pathological states of organism is supposed.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 3","pages":"3-11"},"PeriodicalIF":0.0,"publicationDate":"1998-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Conformational modifications of smooth muscle light chain kinase]. 平滑肌轻链激酶的构象修饰。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-05-01
A M Filenko, V S Omel'ianiuk, V M Danylova, A Sobieszek
{"title":"[Conformational modifications of smooth muscle light chain kinase].","authors":"A M Filenko,&nbsp;V S Omel'ianiuk,&nbsp;V M Danylova,&nbsp;A Sobieszek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Our recent investigations have shown that smooth muscle myosin light chain kinase (MLCK) exists in solution as a mixture of oligomeric, dimeric and monomeric species; besides during preincubation (maintaining of the activated enzyme without substrate) with substoichiometric amounts of calmodulin (CaM) it undergoes definite changes leading to several fold lowering of its activity. Fluorescent data obtained in this work suggest that such kinase inhibition must not be connected with quantitative redistribution of different kinase species but rather it is the result of conformational modifications of this enzyme activated molecules leading to the reduction of their affinity to CaM. Such conformational rearrangements took place also at equimolar kinase to CaM ratio (or CaM excess) but in this case they were characterized by lower depth and insignificant MLCK activity fall. The nature of these conformational changes is discussed.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 3","pages":"43-9"},"PeriodicalIF":0.0,"publicationDate":"1998-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Biochemical mechanisms of the toxic effect of oxalates]. [草酸盐毒性作用的生化机制]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-05-01
K N Khlus
{"title":"[Biochemical mechanisms of the toxic effect of oxalates].","authors":"K N Khlus","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of oxalic acid and its salts on the biochemical systems of the homeostasis of white rats were investigated. It has been shown that oxalates inhibit enzymes of energy metabolism and cause the changes in parameters of nephrotoxicity, electrolyte balance of blood plasma and urine, lipid peroxidation, antiperoxidational defence system.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 3","pages":"95-102"},"PeriodicalIF":0.0,"publicationDate":"1998-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Structural-functional changes in membranes and external perimembrane layers of erythrocytes in hyperepidermopoiesis]. [表皮增生过程中红细胞膜和外膜周层结构功能的改变]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-05-01
G A Semko
{"title":"[Structural-functional changes in membranes and external perimembrane layers of erythrocytes in hyperepidermopoiesis].","authors":"G A Semko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The coat properties of erythrocytes in hyperepidermopoesis had been studied using the vital quantitative method of the cell coat (outer perimembraneous layer) identification with alcian blue (AB). It is shown that the stage sharpening in psoriasis was accompanied an increase in AB sorption by erythrocytes for 13.2. The qualitative and quantitative gangliosidic spectrum of erythrocytes and serum does change according to the date of chromatography in hyperepidermopoesis. The role of this changes are discussed in pathogenesis of the given disease.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 3","pages":"113-8"},"PeriodicalIF":0.0,"publicationDate":"1998-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Dynamics of the interaction of monoclonal antibodies with antigens immobilized on plates]. 单克隆抗体与固定在板上抗原相互作用的动力学研究。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-05-01
S A Bobrovnik
{"title":"[Dynamics of the interaction of monoclonal antibodies with antigens immobilized on plates].","authors":"S A Bobrovnik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A new method to determine a rate constant and total reaction product using data of reaction product kinetics is proposed. The method is based on the solution of the system of irrational equations (for special case), which describes such processes. This method was used to determine the reaction rate constant of interaction of some monoclonal antibodies with the antigens immobilized on immunological plates.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 3","pages":"118-28"},"PeriodicalIF":0.0,"publicationDate":"1998-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Study of sorption properties of organosilanes to be used as the basis for hemosorbents and diagnostic enzyme and immunosensors]. [有机硅烷的吸附特性研究，作为血液吸附剂、诊断酶和免疫传感器的基础]。
Ukrainskii biokhimicheskii zhurnal (1978) Pub Date : 1998-05-01
V M Starodub
{"title":"[Study of sorption properties of organosilanes to be used as the basis for hemosorbents and diagnostic enzyme and immunosensors].","authors":"V M Starodub","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The abilities of different types of organosilanes, in particular of polymers with: 1) completely or 2) partially hydrophobical surfaces; 3) regular changes of part of silicium ions by metal ions; 4) preliminary aminosilanization were studied for sorption of ammonia ions, urea, cholesterol, creatinine, albumin, IgG, haemoglobin and myoglobin. Polymethylsiloxane was used as haemosorbent for directed sorption of myoglobin and haemoglobin from solution and blood. It didn't hemolysate red cells. The high efficiency of those organosilanes for sorption of haemoproteins it was shown. Organosilanes were very good as membrane for immobilization of urease and IgG-specific antibodies to create enzyme sensor and immunosensor based on the ionsensitive field effect transistors. The advantages and possibilities of organosilane usage as haemosorbents in the field of medicine of catastrophes as well as for sensor technology are discussed.</p>","PeriodicalId":76775,"journal":{"name":"Ukrainskii biokhimicheskii zhurnal (1978)","volume":"70 3","pages":"56-63"},"PeriodicalIF":0.0,"publicationDate":"1998-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20757727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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