{"title":"Klion infusion for controlling surgical and other bacterial gynaecological febrile complications.","authors":"A Varga, J Lovas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The incidence of febrile infectious postoperative complications following Caesarean sections and gynaecological major operations during 2 two-year periods has been retrospectively analysed. In the operated group receiving Klion infusion as an adjuvant to postoperative therapy infectious febrile complication occurred only in 2.63% of the cases versus the 6.73% of the control period without Klion therapy. The acute period of febrile acute pelvic inflammations decreased to 1-2 days in women treated with Klion infusion as well, versus the 3-4 days of the control cases. The study proved that prevention and therapy with metronidazole infusion decrease the incidence of complications and inflammations in which anaerobic pathogens play an important to about 50%.</p>","PeriodicalId":76737,"journal":{"name":"Therapia Hungarica (English edition)","volume":"39 2","pages":"93-5"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13107292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Several years of observation with Mydeton in the treatment of lockjaw.","authors":"J Inovay, J Katona","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Several years' observations with the muscle relaxant Mydeton (150 mg coated tablet) in the treatment of lockjaw of different etiology have been discussed. The trismus relieving action of the drug was proved by objective examinations. It has been concluded that Mydeton is of high therapeutic value in relieving muscular spasms of the maxillofocal region of different etiology and it may be used without risk in both hospitalized cases and outpatients.</p>","PeriodicalId":76737,"journal":{"name":"Therapia Hungarica (English edition)","volume":"39 4","pages":"185-7"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12973133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Hájková, M Prichlik, M Bártová, L Brezinová, M Hatala
{"title":"Klion in the prevention of early complications following appendectomy.","authors":"H Hájková, M Prichlik, M Bártová, L Brezinová, M Hatala","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors observations with prophylactic administration of metronidazole manufactured by the Gedeon Richter Company, Hungary (trade mark Klion) in children with phlegmonous appendicitis are reported. The drug was administered in three doses to 51 children. Results of bacteriology could be assessed in 42 children. The results of prophylactic administration of Klion in phlegmonous appendicitis were excellent. In our group there were no inflammatory wounds and/or intraperitoneal complications. For comparison, in a cohort of 1.008 children with phlegmonous appendicitis, without prophylaxis the rate of inflammatory complications was 3.62%. Klion has minimal side effects and is well tolerated and seems to be a superb drug for prophylaxis.</p>","PeriodicalId":76737,"journal":{"name":"Therapia Hungarica (English edition)","volume":"39 1","pages":"25-9"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13018394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical muscle relaxation with Norcuron injection.","authors":"G Takács","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Norcuron, a new, non-depolarizing muscle relaxant has been used for anaesthesia of 48 obstetrical and gynaecological operations. The product could assure the required neuromuscular blockade in all discussed operation types when given either in single or repeated doses. It's action developed rapidly and, if required, it could be antagonized within a short period. The drug had no unfavourable circulation influencing side-effect and could be combined with the used anaesthetics. In newborns delivered by Caesarean section pathological changes were observed nor in Apgar scores, neither in the cardiorespiratory adaptation.</p>","PeriodicalId":76737,"journal":{"name":"Therapia Hungarica (English edition)","volume":"39 1","pages":"19-21"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12842454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of benzodiazepines in psychiatry.","authors":"J Harangozó, I Magyar, G Faludy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Benzodiazepines are generally well tolerated (compared to barbiturates or antidepressants, their side-effects are milder). They may be used safely, their toxicity is low. Benzodiazepine overdosage may be lethal only if the drug is taken simultaneously with other drugs or alcohol. They act primarily through inhibiting the GABA system, their anxiolytic and sedative effects are of primary importance from the psychiatric aspect. Their classification is based on the difference in their receptor affinity (potency) and kinetics. Derivatives of low, medium and high potency are known. The introduction of high potency benzodiazepines in psychiatry has increased the therapeutic means. The major field of indication of benzodiazepine therapy is DSM-III anxiety disorders and insomnias but they may be successfully used in the treatment of manic conditions, schizophrenia, delirium tremens, clinical conditions accompanied by anxiety-depression, acute restlessness, neuroleptic-induced acute distonias, and akathisias. Even if therapeutic doses are used, tolerance to benzodiazepines may develop after some weeks of therapy. The general withdrawal symptoms are not severe, but the rebound symptoms often hinder the discontinuance of the drug or the reduction of doses. When prescribing benzodiazepines the risk of long-term therapy and the prevention of the development of drug addiction have to be considered.</p>","PeriodicalId":76737,"journal":{"name":"Therapia Hungarica (English edition)","volume":"39 3","pages":"103-11"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12981892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of interferon in clinical practice.","authors":"L Sréter, J Fehér","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Interferons are currently the most widely used biological response modifiers. They are of high clinical value in haematological malignancies (chronic myelogenous leukaemia, multiple myeloma, non-Hodgkin lymphoma), in solid tumours (malignant melanoma, hypernephroma, pancreas neoplasms, carcinoid tumours, Kaposi's sarcoma, glioma, in ovarium, cervix and bladder carcinoma, and in basalioma) and in infectious diseases (chronic hepatitis B, chronic non-A/non-B hepatitis, chronic delta hepatitis, AIDS, Papova virus and Rhinovirus infections, leishmaniasis, leprosy) and some other conditions. Although the mechanism of action of interferons has not been explained in every detail these agents are promising therapeutic means in a number of diseases.</p>","PeriodicalId":76737,"journal":{"name":"Therapia Hungarica (English edition)","volume":"39 4","pages":"159-66"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12889657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Thrombosis prophylaxis with subcutaneous heparin Ca injection in the course of caesarean sections.","authors":"J Varga, I Varga","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Subcutaneous low-dose Heparin Ca injections were given as prophylactic treatment to 31 women who were candidates for Caesarean section and were at high risk of thrombo-embolism. Postoperative deep vein thrombosis or pulmonary embolism did not occur in the treated cases. Local or systemic haemorrhages or other reactions were not observed. The controlled haematological parameters changed as expected. According to the opinion of the authors Heparin Ca may be successfully used for the prevention of the postoperative complications of Caesarean section.</p>","PeriodicalId":76737,"journal":{"name":"Therapia Hungarica (English edition)","volume":"39 1","pages":"41-3"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13018396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}