The Indian journal of chest diseases & allied sciences最新文献_第9页

Role of nitric oxide in the diuresis and natriuresis occurring in patients with obstructive sleep apnoea syndrome. 一氧化氮在阻塞性睡眠呼吸暂停综合征患者利尿和尿钠中的作用

The Indian journal of chest diseases & allied sciences Pub Date : 2022-06-10 DOI: 10.5005/ijcdas-53-1-11

T. Singh, K. Patial, V. Vijayan, K. Ravi

{"title":"Role of nitric oxide in the diuresis and natriuresis occurring in patients with obstructive sleep apnoea syndrome.","authors":"T. Singh, K. Patial, V. Vijayan, K. Ravi","doi":"10.5005/ijcdas-53-1-11","DOIUrl":"https://doi.org/10.5005/ijcdas-53-1-11","url":null,"abstract":"OBJECTIVE\u0000To determine whether nitric oxide (NO) has any role in the diuresis and natriuresis observed in patients with obstructive sleep apnoea syndrome (OSAS).\u0000\u0000\u0000METHODS\u0000We measured 12-hour urine volume in the day and in the night in patients with OSAS (n=20) and determined the concentrations of urinary sodium and nitrate. The frequency of urination in the night was also noted. The measurements were done again after two nights of continuous positive airway pressure (CPAP) therapy and after putting the patients on oral anti-oxidant treatment (vitamin C-100 mg BD and vitamin E-400 IU BD) for 45 days. Ten healthy normal subjects underwent the same protocol except the CPAP therapy.\u0000\u0000\u0000RESULTS\u0000In patients with OSAS, the night urine volume and sodium concentration were similar and the nitrate levels were higher compared to those in the day. After CPAP therapy, while the urine volume and sodium concentration decreased, the nitrate level became similar to that in the day. Such effects were not observed after anti-oxidant treatment. The frequency of urination was decreased in both the instances. The effects observed after CPAP therapy were similar to those observed in control subjects with or without anti-oxidant treatment.\u0000\u0000\u0000CONCLUSION\u0000Renal NO promotes diuresis and natriuresis in patients with OSAS.","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"51 1","pages":"11-20"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86696164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffuse panbronchiolitis associated with malignant thymoma. 弥漫性泛细支气管炎伴恶性胸腺瘤。

The Indian journal of chest diseases & allied sciences Pub Date : 2022-06-10 DOI: 10.5005/ijcdas-52-1-41

Snehal Jadhav, J. Joshi

引用次数: 6

Why "STOP TB" is incomplete without "QUIT SMOKING". 为什么没有“戒烟”的“遏制结核病”是不完整的。

The Indian journal of chest diseases & allied sciences Pub Date : 2022-06-10 DOI: 10.5005/ijcdas-53-1-9

Z. Udwadia, L. Pinto

引用次数: 5

Validity of pneumonia severity index and CURB-65 severity scoring systems in community acquired pneumonia in an Indian setting. 印度社区获得性肺炎肺炎严重程度指数和CURB-65严重程度评分系统的有效性

The Indian journal of chest diseases & allied sciences Pub Date : 2022-06-10 DOI: 10.5005/ijcdas-52-1-9

Bashir Ahmed Shah, W. Ahmed, G. N. Dhobi, N. Shah, S. Khursheed, I. Haq

{"title":"Validity of pneumonia severity index and CURB-65 severity scoring systems in community acquired pneumonia in an Indian setting.","authors":"Bashir Ahmed Shah, W. Ahmed, G. N. Dhobi, N. Shah, S. Khursheed, I. Haq","doi":"10.5005/ijcdas-52-1-9","DOIUrl":"https://doi.org/10.5005/ijcdas-52-1-9","url":null,"abstract":"BACKGROUND\u0000Little information is available from India regarding prognostic factors in patients with community acquired pneumonia (CAP).\u0000\u0000\u0000METHODS\u0000Hospital-based prospective study to test the validity of pneumonia severity index (PSI) and the confusion, urea, respiratory rate, blood pressure, age over 65 years (CURB-65) risk scoring systems in patients with CAP (n=150).\u0000\u0000\u0000RESULTS\u0000Although both CURB-65 class > or = III and PSI class > or = IV were 100% sensitive in predicting death, CURB-65 class > or = III had a higher specificity (74.6%) than PSI class > or = IV (52.2%) when used to predict death. In both PSI and CURB-65 risk scoring systems, mortality rate, need for intensive care unit (ICU) admission, prolonged need for intravenous (I.V.) antibiotics, prolonged duration of hospital stay and need for admission to ICU increased progressively with increasing scores. The PSI class > or = IV was more sensitive in predicting ICU admission than CURB-65. The duration of hospital stay was found to have a weak but significant correlation with PSI and CURB-65 criteria. Defervescence time also had a very weak but significant correlation with PSI and CURB-65 criteria. Duration of I.V. antibiotics had a moderately strong correlation with CURB-65 criteria but a weak correlation with PSI criteria.\u0000\u0000\u0000CONCLUSIONS\u0000Both PSI and CURB-65 were found to have equal sensitivity to predict death from CAP. Specificity of CURB-65 was higher than that of PSI. However, PSI was more sensitive in predicting ICU admission than CURB-65.","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"17 1","pages":"9-17"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80181461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 77

Prevalence of depression in stable chronic obstructive pulmonary disease. 稳定期慢性阻塞性肺疾病患者抑郁的患病率

The Indian journal of chest diseases & allied sciences Pub Date : 2022-06-10 DOI: 10.5005/ijcdas-53-1-35

S. De

{"title":"Prevalence of depression in stable chronic obstructive pulmonary disease.","authors":"S. De","doi":"10.5005/ijcdas-53-1-35","DOIUrl":"https://doi.org/10.5005/ijcdas-53-1-35","url":null,"abstract":"BACKGROUND\u0000Psychological impairment is a significant co-morbid condition of chronic obstructive pulmonary disease (COPD). No studies from India have been conducted to assess the prevalence of depression in COPD.\u0000\u0000\u0000METHODS\u0000We investigated the prevalence of depression in 100 consecutive stable COPD patients during their routine outpatient department visits. Patients diagnosed to have depression or chronic systemic diseases were excluded. Severity of the COPD was classified according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines. Hindi translations of patient health questionnaire-9 (PHQ-9) were administered and severity of depression was assessed at each stage of the COPD.\u0000\u0000\u0000RESULTS\u0000All subjects were males with a mean age of 61.7 +/- 9.6 years. Six patients in stage I, 32 patients in stage II, 40 patients in stage III and 22 patients in stage IV of the COPD were enrolled. The cumulative prevalence of depression in the study population was 72 percent.\u0000\u0000\u0000CONCLUSIONS\u0000Symptoms of depression were observed at all stages of COPD and its severity increased with an increase in severity of the COPD. High prevalence of depressive symptoms in Indian patients with COPD may be due to various confounding factors. Screening for symptoms of depression in patients with COPD by simple and quick validated questionnaires during their out-patient visits will be helpful in early diagnosis and appropriate treatment or referral.","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"41 1","pages":"35-9"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88007911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 36

Allergen immunotherapy: the scientific facts. 过敏原免疫疗法:科学事实。

The Indian journal of chest diseases & allied sciences Pub Date : 2022-06-10 DOI: 10.5005/ijcdas-53-4-205

S. Gaur

引用次数: 0

Adiposity: determinant of peak expiratory flow rate in young Indian adults male. 肥胖:印度年轻男性呼气流量峰值的决定因素。

The Indian journal of chest diseases & allied sciences Pub Date : 2022-06-10 DOI: 10.5005/ijcdas-53-1-29

Yogesh Saxena, B. Purwar, Rashi Upmanyu

{"title":"Adiposity: determinant of peak expiratory flow rate in young Indian adults male.","authors":"Yogesh Saxena, B. Purwar, Rashi Upmanyu","doi":"10.5005/ijcdas-53-1-29","DOIUrl":"https://doi.org/10.5005/ijcdas-53-1-29","url":null,"abstract":"BACKGROUND\u0000Although several factors such as respiratory muscle strength, lung compliance, resistance to airflow, and even obesity affect the lung functions, the nature of relationship with markers of adiposity is not clear. We hypothesised that central pattern of fat distribution is a significant predictor of decreased peak expiratory flow rate (PEFR). The present study was designed with the aim to examine the effects of adiposity on PEFR in males.\u0000\u0000\u0000METHODS\u0000One hundred young healthy male volunteers were analysed in the study. They were classified into non-obese, and obese groups based on body mass index (BMI) (obese > or = 30 Kg/m2 and non-obese < 30 Kg/m2). The PEFR was measured by using Wright's peak flow meter. Data was analysed using unpaired 't' test for statistical significance of differences between the non-obese and the obese, stratified into age groups of 20 to 30 years and 30 to 40 years. A partial correlation adjusted to age, height and BMI followed by regression analysis was conducted using adiposity markers as a predictor of PEFR.\u0000\u0000\u0000RESULTS\u0000The model adjusted to age, height, weight and BMI revealed waist hip ratio (WHR) as the only parameter which shows significant variance in PEFR with a Pearson's r=-0.59, F (1, 100)=12.23, p=0.04. The resulting linear regression equation is y=-388.72xWHR+850.68.\u0000\u0000\u0000CONCLUSIONS\u0000Our findings suggest that obesity itself and especially the pattern of body fat distribution have independent effects on PEFR. These results suggest that abdominal adiposity, measured as WHR, is a better predictor of expiratory flow than weight or BMI.","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"22 1","pages":"29-33"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82419987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 38

Statins and the lung: hope or hype? 他汀类药物与肺:希望还是炒作?

The Indian journal of chest diseases & allied sciences Pub Date : 2022-06-10 DOI: 10.5005/ijcdas-53-2-79

Z. Udwadia, Rucha S. Dagaonkar

引用次数: 0

Diagnostic dilemma of antineutrophil cytoplasmic antibody seropositivity in human immunodeficiency virus infection. 人免疫缺陷病毒感染中抗中性粒细胞细胞质抗体血清阳性的诊断困境。

The Indian journal of chest diseases & allied sciences Pub Date : 2022-06-10 DOI: 10.5005/ijcdas-53-1-55

P. Mohapatra, S. Khanduri, N. Dutt, Preeti Sharma, A. Janmeja

引用次数: 2

Nosing around in chronic obstructive pulmonary disease. 慢性阻塞性肺疾病的鼻塞。

The Indian journal of chest diseases & allied sciences Pub Date : 2022-06-10 DOI: 10.5005/ijcdas-53-1-5

A. Shah

引用次数: 3