Cyrus Chargari, D. Macdermed, Pierre-Emmanuel Tardo-Dino, P. Castadot, N. Magné
{"title":"Cannon ball lucencies from last century: lucite balls used to treat pulmonary tuberculosis.","authors":"Cyrus Chargari, D. Macdermed, Pierre-Emmanuel Tardo-Dino, P. Castadot, N. Magné","doi":"10.5005/ijcdas-52-1-59","DOIUrl":"https://doi.org/10.5005/ijcdas-52-1-59","url":null,"abstract":"","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"40 1","pages":"59"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77697016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Mootha, R. Agarwal, N. Singh, A. Aggarwal, D. Gupta, S. Jindal
{"title":"Medical thoracoscopy for undiagnosed pleural effusions: experience from a tertiary care hospital in north India.","authors":"V. Mootha, R. Agarwal, N. Singh, A. Aggarwal, D. Gupta, S. Jindal","doi":"10.5005/ijcdas-53-1-21","DOIUrl":"https://doi.org/10.5005/ijcdas-53-1-21","url":null,"abstract":"BACKGROUND AND AIMS\u0000Medical thoracoscopy, also called pleuroscopy, has received renewed interest in the recent past for diagnostic as well as therapeutic uses. In this study, we describe our experience with thoracoscopy for undiagnosed pleural effusions.\u0000\u0000\u0000METHODS\u0000In a retrospective analysis of thoracoscopic procedures we performed between January 2007 and December 2008, yield of thoracoscopic pleural biopsy for achieving a diagnosis in undiagnosed pleural effusions, defined as pleural effusions with adenosine deaminase (ADA) levels less than 70 IU/L and negative pleural fluid cytology for malignancy on three occasions was evaluated. Complications of thoracoscopy were also analysed.\u0000\u0000\u0000RESULTS\u0000Overall diagnostic yield of thoracoscopic pleural biopsy was 74.3% in patients with undiagnosed pleural effusions. Pleural malignancy was diagnosed in 48.6% of patients. There was only one case of mesothelioma and the rest were due to pleural metastasis. Lung cancer and breast cancer were the most common sites of primary malignancy. Tuberculosis was diagnosed with pleural biopsy in 22.8% of patients. We had low complication rate after thoracoscopy. Only two cases of empyema were observed.\u0000\u0000\u0000CONCLUSION\u0000Medical thoracoscopy is a safe procedure and has good diagnostic yield in patients with undiagnosed pleural effusions.","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"110 1","pages":"21-4"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88601844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sheetu Singh, M. Soumya, Anirudh Saini, V. Mittal, Udaiveer Singh, Virendra Singh
{"title":"Breath carbon monoxide levels in different forms of smoking.","authors":"Sheetu Singh, M. Soumya, Anirudh Saini, V. Mittal, Udaiveer Singh, Virendra Singh","doi":"10.5005/ijcdas-53-1-25","DOIUrl":"https://doi.org/10.5005/ijcdas-53-1-25","url":null,"abstract":"BACKGROUND AND OBJECTIVES\u0000Bidi, cigarette, hookah and chillum are common modes of tobacco smoking in India. Many people consider hookah and chillum smoking less toxic because smoke is filtered through water or wet cloth. We evaluated the toxicity of tobacco smoking by measuring end-tidal carbon monoxide (eCO) levels after various modes of smoking.\u0000\u0000\u0000METHODS\u0000Eighteen healthy smokers who smoked bidi, cigarette, hookah and chillum on six days were studied. They smoked one bidi, one cigarette, five minutes hookah, one serve (15 minutes) hookah, five minutes chillum and one serve (15 minutes) chillum on six days randomly. The eCO values were measured before initiation of smoking and for a period of one hour after the smoking session. Increase in eCO values in comparison to baseline after different modes of smoking was compared.\u0000\u0000\u0000RESULTS\u0000In comparison to baseline, mean eCO levels were raised by 4.94 (0.96) parts per million (ppm) immediately and 4.17 (1.07) ppm 60 minutes after cigarette smoking. Bidi smoking caused slightly less increase in mean eCO levels (3.17 [0.82]). One serve of hookah and chillum smoking caused elevation of mean eCO values by almost eight-folds higher than that of cigarette smoking. Five minutes of smoking with hookah (22.18 [5.29]) and one serve of hookah (33.0 [8.76]) and chillum (40.14 [12.73]) caused significantly higher values of mean increase in eCO in comparison to cigarette smoking (p<0.001).\u0000\u0000\u0000CONCLUSION\u0000With regard to eCO levels, hookah and chillum smoking are much more toxic than cigarette smoking.","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"46 1","pages":"25-8"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77282042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Ramya, K. P. Mathews, K. Pichamuthu, S. Keshava, T. Balamugesh, M. Ramamani, V. Surekha, T. Mammen
{"title":"Endotracheal tuberculous stenosis: ventilation rescue and bronchography guided stenting.","authors":"I. Ramya, K. P. Mathews, K. Pichamuthu, S. Keshava, T. Balamugesh, M. Ramamani, V. Surekha, T. Mammen","doi":"10.5005/ijcdas-52-1-55","DOIUrl":"https://doi.org/10.5005/ijcdas-52-1-55","url":null,"abstract":"We present the case of a 16-year-old female patient who presented with dyspnoea, cough and noisy breathing that progressed further in hospital with the development of stridor and severe respiratory compromise requiring mechanical ventilatory support. Investigations were consistent with a diagnosis of endotracheal tuberculosis with tracheal and bronchial stenosis. Despite adequate anti-tuberculous therapy and ventilation the patient had high airway pressures, low tidal volumes and hypercapnia, which prevented weaning from mechanical ventilation. Balloon dilatation and stenting of the 4.5cm long, 2.3mm diameter stenotic tracheal segment was performed under radiological guidance. The patient was weaned successfully from the ventilator post-procedure. This report illustrates the successful management of an uncommon presentation of a common disease with modern endoscopic therapy.","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"12 1","pages":"55-8"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88755918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulmonary hypertension associated with chronic obstructive pulmonary disease.","authors":"S. Chhabra","doi":"10.5005/ijcdas-52-1-29","DOIUrl":"https://doi.org/10.5005/ijcdas-52-1-29","url":null,"abstract":"Pulmonary hypertension (PH) is likely to complicate chronic obstructive pulmonary disease (COPD) in a large proportion of patients, especially those with severe disease. Majority of patients have a mild to moderate elevation in the pulmonary artery pressure that usually does not require specific treatment. A small subset of patients, however, develops severe PH that is \"out-of-proportion\" to the severity of COPD. Generally considered a consequence of chronic hypoxaemia, endothelial dysfunction has now been recognised to play an important role in the pathogenesis of PH in COPD. Pulmonary vessels remodelling characterised by intimal enlargement with proliferating smooth muscle cells, medial hypertrophy, arteriolar muscularisation and endothelial cell proliferation, especially affecting the small arterioles and arteries, leads to permanent changes in the vascular structure and function. Clinical recognition of PH is difficult. Echocardiography is used for screening while right heart catheterisation is the gold standard for diagnosis. In patients who have a moderate degree of chronic hypoxaemia, long term oxygen therapy is indicated and is the only therapeutic measure so far known to retard the progress of PH. Newer therapies targeting the specific abnormalities of vasoconstrictor-vasodilator balance, arising as a consequence of endothelial dysfunction, are under investigation and may offer a management option especially in severe PH associated with COPD.","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"24 1","pages":"29-40"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75843203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Thangakunam, D. Christopher, P. James, Richa Gupta
{"title":"Semi-rigid thoracoscopy: initial experience from a tertiary care hospital.","authors":"B. Thangakunam, D. Christopher, P. James, Richa Gupta","doi":"10.5005/ijcdas-52-1-25","DOIUrl":"https://doi.org/10.5005/ijcdas-52-1-25","url":null,"abstract":"BACKGROUND\u0000Thoracoscopy is usually carried out using rigid metallic instruments. Recently, video flex-rigid or semi-rigid thoracoscopes have been introduced. These have the advantage of easy maneuverability, although the biopsy samples are smaller as compared to those with rigid thoracoscopy. We have looked at the usefulness of flex rigid thoracoscope in the diagnosis and treatment of pleural diseases, remained undiagnosed after thoracentesis and closed biopsy.\u0000\u0000\u0000METHODS\u0000Retrospective analysis of data of patients who underwent thoracoscopy for the evaluation of pleural disease.\u0000\u0000\u0000RESULTS\u0000Thoracoscopy was done in 21 patients using a flex-rigid thoracoscope in our institution. The indication was pleural effusion with inconclusive or negative pleural fluid cytology and blind pleural biopsy in 18 of the 21 patients. Thoracoscopic biopsy was positive in 12 of the 18 patients (66.7%). Of the six who had a negative biopsy, the procedure indirectly helped in patient management in five. There were no significant procedure-related complications.\u0000\u0000\u0000CONCLUSION\u0000Thoracoscopy with flex-rigid thoracoscope is a useful diagnostic tool in the evaluation of pleural effusions with negative blind pleural biopsy and cytology.","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"61 1","pages":"25-7"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73246475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Fékih, S. Fenniche, H. Hassène, H. Abdelghaffar, S. Yaâlaoui, F. ElMezni, D. Belhabib, A. Zidi, M. L. Megdiche
{"title":"Multiple myeloma presenting with multiple thoracic manifestations.","authors":"L. Fékih, S. Fenniche, H. Hassène, H. Abdelghaffar, S. Yaâlaoui, F. ElMezni, D. Belhabib, A. Zidi, M. L. Megdiche","doi":"10.5005/ijcdas-52-1-47","DOIUrl":"https://doi.org/10.5005/ijcdas-52-1-47","url":null,"abstract":"Multiple myeloma is a malignant proliferation of plasma cells that affects mainly bone marrow but may also involve other organs as well. We report thoracic involvement in the form of left-sided pleural effusion, osseous lesions, bronchial infiltration, and mediastinal lymphadenopathy in a 61-year-old woman, non-smoker presented with chest pain, dyspnoea, cough and deterioration in general health over the preceding seven months. Immunoelectrophoresis and immunofixation showed raised kappa-light chain immunoglobulin G (IgG) in serum and pleural fluid. Bronchial and pleural biopsies documented myelomatous infiltration and bone marrow aspirate revealed extensive plasma cell infiltration. At eight months, following the fourth cycle of melphalan, endoxan and prednisone based chemotherapy, the patient died.","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"1 1","pages":"47-9"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76172708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perils of injudicious medical imaging: time for a wake-up call!","authors":"G. Ahluwalia, A. Ahluwalia, S. Sharma","doi":"10.5005/ijcdas-52-2-77","DOIUrl":"https://doi.org/10.5005/ijcdas-52-2-77","url":null,"abstract":"","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"23 1","pages":"77-8"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74215691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immune responses to mycobacterial antigens in sarcoidosis: a systematic review.","authors":"D. Gupta, R. Agarwal, A. Aggarwal, I. Verma","doi":"10.5005/ijcdas-53-1-41","DOIUrl":"https://doi.org/10.5005/ijcdas-53-1-41","url":null,"abstract":"From the time sarcoidosis has been described, there has always been a viewpoint that the disease is in some way related to tuberculosis (TB). Sarcoidosis is a granulomatous disease, which is likely a result of continued presentation of a poorly degradable antigen. Mycobacterium tuberculosis has been a very strong contender for this antigen. Besides the molecular studies demonstrating mycobacterial deoxyribonucleic acid (DNA) in the sarcoid tissue, assessment of immune responses against mycobacterial antigens provides a useful tool to study the role of mycobacteria in the pathogenesis of sarcoidosis. We reviewed the studies focussing on T-cell and B-cell responses to tubercular antigens in patients with sarcoidosis. Pooled data from various studies does provide a suggestive, though not unequivocal evidence in favour of mycobacteria as a cause of sarcoidosis. These findings not only reinforce the possible pathogenic role of mycobacterial antigens in sarcoidosis, but at the same time also limit the clinical utility of molecular and serological studies based on mycobacterial antigens in the differential diagnosis of TB from sarcoidosis, particularly in a country with high endemicity for TB.","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"55 1","pages":"41-9"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87121603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cholinergics, airway eosinophils and asthma exacerbation in the elderly.","authors":"D. Khalil, J. Hirota, Parameswaran Nair","doi":"10.5005/ijcdas-53-1-59","DOIUrl":"https://doi.org/10.5005/ijcdas-53-1-59","url":null,"abstract":"Cholinomimetic agents have a number of potential indications in an ageing population. This case series emphasises the need to exercise caution while prescribing cholinergic drugs in elderly patients with asthma, particularly in patients with a history of virus-induced exacerbations and airway eosinophilia.","PeriodicalId":76635,"journal":{"name":"The Indian journal of chest diseases & allied sciences","volume":"21 1","pages":"59-61"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83241396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}