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Recent advances in otitis media. 6. Vaccine. 中耳炎的最新进展。6. 疫苗
The Annals of otology, rhinology & laryngology. Supplement Pub Date : 2005-01-01
G Scott Giebink, Yuichi Kurono, Lauren O Bakaletz, Jennelle M Kyd, Stephen J Barenkamp, Timothy F Murphy, Bruce Green, Pearay L Ogra, Xin-Xing Gu, Janak A Patel, Terho Heikkinen, Stephen I Pelton, Muneki Hotomi, Pekka Karma
{"title":"Recent advances in otitis media. 6. Vaccine.","authors":"G Scott Giebink, Yuichi Kurono, Lauren O Bakaletz, Jennelle M Kyd, Stephen J Barenkamp, Timothy F Murphy, Bruce Green, Pearay L Ogra, Xin-Xing Gu, Janak A Patel, Terho Heikkinen, Stephen I Pelton, Muneki Hotomi, Pekka Karma","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76600,"journal":{"name":"The Annals of otology, rhinology & laryngology. Supplement","volume":"194 ","pages":"86-103"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24948185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent advances in otitis media. 2. Eustachian tube, middle ear, and mastoid anatomy; physiology, pathophysiology, and pathogenesis. 中耳炎的最新进展。2. 耳咽管、中耳和乳突解剖;生理学、病理生理学和发病机制。
The Annals of otology, rhinology & laryngology. Supplement Pub Date : 2005-01-01 DOI: 10.1177/00034894051140s105
Charles D Bluestone, Patricia A Hebda, Cuneyt M Alper, Isamu Sando, Craig A Buchman, Sven-Eric Stangerup, Jens U Felding, J Douglas Swarts, Samir N Ghadiali, Haruo Takahashi
{"title":"Recent advances in otitis media. 2. Eustachian tube, middle ear, and mastoid anatomy; physiology, pathophysiology, and pathogenesis.","authors":"Charles D Bluestone, Patricia A Hebda, Cuneyt M Alper, Isamu Sando, Craig A Buchman, Sven-Eric Stangerup, Jens U Felding, J Douglas Swarts, Samir N Ghadiali, Haruo Takahashi","doi":"10.1177/00034894051140s105","DOIUrl":"https://doi.org/10.1177/00034894051140s105","url":null,"abstract":"","PeriodicalId":76600,"journal":{"name":"The Annals of otology, rhinology & laryngology. Supplement","volume":"194 ","pages":"16-30"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/00034894051140s105","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24948179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 75
Recent advances in otitis media. Report of the Eighth Research Conference. June 3-7, 2003. Fort Lauderdale, Florida, USA. 中耳炎的最新进展。第八届研究会议报告。2003年6月3日至7日。劳德代尔堡，美国佛罗里达州。
The Annals of otology, rhinology & laryngology. Supplement Pub Date : 2005-01-01
{"title":"Recent advances in otitis media. Report of the Eighth Research Conference. June 3-7, 2003. Fort Lauderdale, Florida, USA.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76600,"journal":{"name":"The Annals of otology, rhinology & laryngology. Supplement","volume":"194 ","pages":"6-160"},"PeriodicalIF":0.0,"publicationDate":"2005-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25154127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Etiology of chronic rhinosinusitis: the role of fungus. 慢性鼻窦炎的病因:真菌的作用。
The Annals of otology, rhinology & laryngology. Supplement Pub Date : 2004-05-01 DOI: 10.1177/00034894041130s508
Daniel L Hamilos, Valerie J Lund
{"title":"Etiology of chronic rhinosinusitis: the role of fungus.","authors":"Daniel L Hamilos,&nbsp;Valerie J Lund","doi":"10.1177/00034894041130s508","DOIUrl":"https://doi.org/10.1177/00034894041130s508","url":null,"abstract":"<p><p>Chronic rhinosinusitis is an inflammatory disorder with numerous predisposing factors, including genetics, pollution, anatomic anomalies, bacteria, and fungus. In some studies, fungi have been cultured from nearly 100% of patients with rhinosinusitis and nasal polyposis. T-cell sensitization to fungus with production of the T-helper 2 (Th2) cytokine interleukin-5 has been proposed as a key step in the initiation of the disease. Interleukin-5 also plays an important role in the effector phase of the disease through its effects on eosinophilopoesis and eosinophil survival. There is considerable controversy concerning the role of fungi as the cause of \"chronic eosinophilic rhinosinusitis\" and whether this even represents a distinct clinical entity. Further study is also required to define the optimal treatment for the disease.</p>","PeriodicalId":76600,"journal":{"name":"The Annals of otology, rhinology & laryngology. Supplement","volume":"193 ","pages":"27-31"},"PeriodicalIF":0.0,"publicationDate":"2004-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/00034894041130s508","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24546597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 43
Epidemiology and economic impact of rhinosinusitis. 鼻窦炎的流行病学和经济影响。
The Annals of otology, rhinology & laryngology. Supplement Pub Date : 2004-05-01 DOI: 10.1177/00034894041130s502
Vijay K Anand
{"title":"Epidemiology and economic impact of rhinosinusitis.","authors":"Vijay K Anand","doi":"10.1177/00034894041130s502","DOIUrl":"https://doi.org/10.1177/00034894041130s502","url":null,"abstract":"<p><p>Rhinosinusitis is highly prevalent in the United States, affecting an estimated 16% of the adult population annually. The prevalence of the illness is increased in women and, relative to other US regions, in individuals living in the South. The direct costs associated with chronic rhinosinusitis are higher than the background costs in managed care patients because of increased office visits and medication prescriptions, and the indirect costs due to restricted activity days are enormous. Rhinosinusitis poses an immense economic burden in the United States. Data concerning the epidemiology and economic impact of the disease are reviewed.</p>","PeriodicalId":76600,"journal":{"name":"The Annals of otology, rhinology & laryngology. Supplement","volume":"193 ","pages":"3-5"},"PeriodicalIF":0.0,"publicationDate":"2004-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/00034894041130s502","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24546711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 386
Role of endoscopy in the management of chronic rhinosinusitis. 内镜在慢性鼻窦炎治疗中的作用。
The Annals of otology, rhinology & laryngology. Supplement Pub Date : 2004-05-01 DOI: 10.1177/00034894041130s505
Frederick A Kuhn
{"title":"Role of endoscopy in the management of chronic rhinosinusitis.","authors":"Frederick A Kuhn","doi":"10.1177/00034894041130s505","DOIUrl":"https://doi.org/10.1177/00034894041130s505","url":null,"abstract":"<p><p>Endoscopy has multiple uses in both the medical and surgical management of chronic rhinosinusitis (CRS). This article reviews applications of endoscopy in preoperative evaluation and postoperative management of CRS. Before operation, nasal endoscopy is the standard for tissue sampling, evaluation of the mucosa, identifying structural alterations, and staging of allergic fungal sinusitis. As part of the surgical procedure, endoscopy may be used to minimize the time needed for postoperative debridement. Applications of endoscopy in in-office medical management of CRS include culturing the sinuses for fungus or bacteria, inserting a cannula for the delivery of drug therapy, and various minor manipulations following a surgical procedure. Perhaps the most important role for endoscopy in patients with CRS is in medical management, particularly in cases involving eosinophilic inflammation. Angled telescopes are important for visualizing areas often overlooked in sinuses that may otherwise appear to be normal, ie, the depths of the maxillary, frontal, or sphenoid sinus. Further use and research are likely to elicit more uses for this important technology.</p>","PeriodicalId":76600,"journal":{"name":"The Annals of otology, rhinology & laryngology. Supplement","volume":"193 ","pages":"15-8"},"PeriodicalIF":0.0,"publicationDate":"2004-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/00034894041130s505","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24546717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Pathogenesis of chronic rhinosinusitis. 慢性鼻窦炎的发病机制。
The Annals of otology, rhinology & laryngology. Supplement Pub Date : 2004-05-01 DOI: 10.1177/00034894041130s503
David W Kennedy
{"title":"Pathogenesis of chronic rhinosinusitis.","authors":"David W Kennedy","doi":"10.1177/00034894041130s503","DOIUrl":"https://doi.org/10.1177/00034894041130s503","url":null,"abstract":"<p><p>Chronic rhinosinusitis (CRS) is a multifactorial disease. Predisposing factors can be divided into environmental and non-host factors, such as pollution, viral infections, smoking, fungus, and bacteria; general host factors, including genetic factors and immune deficiency; and local host factors, including persistent focal inflammation within the ostiomeatal complex. Evidence suggests that the underlying bone in the ostiomeatal complex is actively involved in the disease process of CRS. The evidence concerning a broad range of predisposing factors for CRS is reviewed.</p>","PeriodicalId":76600,"journal":{"name":"The Annals of otology, rhinology & laryngology. Supplement","volume":"193 ","pages":"6-9"},"PeriodicalIF":0.0,"publicationDate":"2004-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/00034894041130s503","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24546712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 126
Imaging for staging of rhinosinusitis. 鼻窦炎的影像学分期。
The Annals of otology, rhinology & laryngology. Supplement Pub Date : 2004-05-01 DOI: 10.1177/00034894041130s506
S James Zinreich
{"title":"Imaging for staging of rhinosinusitis.","authors":"S James Zinreich","doi":"10.1177/00034894041130s506","DOIUrl":"https://doi.org/10.1177/00034894041130s506","url":null,"abstract":"<p><p>Although clinical judgment is sufficient to diagnose rhinosinusitis in many cases, a number of patients with recurrent or complicated sinus disease require imaging studies. Advances in the field of diagnostic imaging techniques such as computed x-ray tomography (CT) and magnetic resonance imaging have enhanced our understanding and management of the disease. Magnetic resonance imaging excels in displaying soft tissue resolution and is superior in demonstrating the presence of neoplasia and fungal sinusitis. but has limited advantages over CT scanning in demonstrating the regional anatomy (bony structure) and in the diagnosis of chronic rhinosinusitis. Computed tomography provides greater detailed information about the paranasal sinuses than do plain radiographic films. Rhinosinusitis staging systems utilizing CT techniques are reviewed. Although results from the Lund-Mackay system appear to be easily reproducible. there are still clinical challenges not addressed by this method of classification. Considering the patency of specific ostiomeatal channels and quantifying the volume of disease may add to the clinical value of future classification systems.</p>","PeriodicalId":76600,"journal":{"name":"The Annals of otology, rhinology & laryngology. Supplement","volume":"193 ","pages":"19-23"},"PeriodicalIF":0.0,"publicationDate":"2004-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/00034894041130s506","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24546594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 120
Biopsy and specimen collection in chronic rhinosinusitis. 慢性鼻窦炎的活检和标本采集。
The Annals of otology, rhinology & laryngology. Supplement Pub Date : 2004-05-01 DOI: 10.1177/00034894041130s507
Richard R Orlandi
{"title":"Biopsy and specimen collection in chronic rhinosinusitis.","authors":"Richard R Orlandi","doi":"10.1177/00034894041130s507","DOIUrl":"https://doi.org/10.1177/00034894041130s507","url":null,"abstract":"<p><p>Biopsy, aspiration, swab, and irrigation of the nose and sinuses are methods used in specimen collection and culture when chronic rhinosinusitis is suspected. Biopsy may be indicated to identify the presence of fungal elements in the mucus or tissues, suspected neoplasm, or inflamed bone. Aspiration directly from the maxillary sinus is considered to be the gold standard for culture, but it is painful. Direct endoscopic-guided culture of the middle meatus appears to be a viable substitute, with swab and suction methods having similar rates of microbiological contamination. Topical delivery methods for irrigating sinus cavities may utilize spray bottles, nebulizers, or a bulb syringe; these have various degrees of efficacy in dispersing materials to the sinuses. Use of the bulb syringe appears to offer broad distribution with limited risk of sample contamination. Specimens must be handled carefully to avoid loss of fungal elements. Advantages and indications of various methods are reviewed.</p>","PeriodicalId":76600,"journal":{"name":"The Annals of otology, rhinology & laryngology. Supplement","volume":"193 ","pages":"24-6"},"PeriodicalIF":0.0,"publicationDate":"2004-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/00034894041130s507","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24546596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Diagnosis of chronic rhinosinusitis. 慢性鼻窦炎的诊断。
The Annals of otology, rhinology & laryngology. Supplement Pub Date : 2004-05-01 DOI: 10.1177/00034894041130s504
Donald C Lanza
{"title":"Diagnosis of chronic rhinosinusitis.","authors":"Donald C Lanza","doi":"10.1177/00034894041130s504","DOIUrl":"https://doi.org/10.1177/00034894041130s504","url":null,"abstract":"<p><p>Chronic rhinosinusitis is a multifactorial disease defined as inflammation of the nasal cavity and paranasal sinuses with a history of at least 12 weeks in duration. The major symptoms include facial pressure or pain, nasal obstruction, discharge or purulence, and hyposmia or anosmia. The minor symptoms include fever, halitosis, fatigue, and dental pain. Microorganisms play a significant role in the persistence and origination of the inflammatory process, although the exact role of these organisms in the pathogenesis of chronic rhinosinusitis is unclear. The clinical diagnosis relies heavily on the patient history and physical examination, which may include nasal endoscopy and computed tomography. Diagnostic techniques are here reviewed.</p>","PeriodicalId":76600,"journal":{"name":"The Annals of otology, rhinology & laryngology. Supplement","volume":"193 ","pages":"10-4"},"PeriodicalIF":0.0,"publicationDate":"2004-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/00034894041130s504","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24546716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
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