American Journal of Psychiatry最新文献

{"title":"Artificial Intelligence as the Computational Framework for Adaptive Closed-Loop Neuromodulation in Psychiatry","authors":"Babak Mahmoudi","doi":"10.1176/appi.ajp.20260137","DOIUrl":"https://doi.org/10.1176/appi.ajp.20260137","url":null,"abstract":"","PeriodicalId":7656,"journal":{"name":"American Journal of Psychiatry","volume":"3 1","pages":"734-742"},"PeriodicalIF":17.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149089434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuromodulation and Precision Therapeutics","authors":"William M. McDonald,Helen S. Mayberg,Patricio Riva Posse,Ned H. Kalin","doi":"10.1176/appi.ajp.20260826","DOIUrl":"https://doi.org/10.1176/appi.ajp.20260826","url":null,"abstract":"","PeriodicalId":7656,"journal":{"name":"American Journal of Psychiatry","volume":"8 1","pages":"685-687"},"PeriodicalIF":17.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149089444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Connectomic Determinants of Subcallosal Cingulate Deep Brain Stimulation for Depression","authors":"Ha Neul Song,Ki Sueng Choi,Brian H. Kopell,Martijn Figee,Jip de Bruin,Jungho Cha,Patricio Riva-Posse,Alexandre Boutet,Gavin Elias,Jurgen Germann,Sidney H. Kennedy,Lyndahl Himes,Robert E. Gross,Andres M. Lozano,Binith Cheeran,Helen S. Mayberg","doi":"10.1176/appi.ajp.20250449","DOIUrl":"https://doi.org/10.1176/appi.ajp.20250449","url":null,"abstract":"","PeriodicalId":7656,"journal":{"name":"American Journal of Psychiatry","volume":"3 1","pages":"764-774"},"PeriodicalIF":17.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149089442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brain Stimulation Therapeutic Interventions in Neuropsychiatry: A Cambrian Explosion","authors":"Harold A. Sackeim,Mark S. George","doi":"10.1176/appi.ajp.20260691","DOIUrl":"https://doi.org/10.1176/appi.ajp.20260691","url":null,"abstract":"","PeriodicalId":7656,"journal":{"name":"American Journal of Psychiatry","volume":"11 1","pages":"696-707"},"PeriodicalIF":17.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149089440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defining Near-Term Treatment Goals for Benzodiazepine Use in Clinical Practice","authors":"Apurva Parikh,Geoffrey Russell,Mark Olfson","doi":"10.1176/appi.ajp.20260426","DOIUrl":"https://doi.org/10.1176/appi.ajp.20260426","url":null,"abstract":"","PeriodicalId":7656,"journal":{"name":"American Journal of Psychiatry","volume":"41 1","pages":""},"PeriodicalIF":17.7,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149020539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Home-Based Neuromodulation for Depression: Rethinking Access and Oversight","authors":"Adela G. Buciuc,Jacob T. Kannarkat,Alik S. Widge","doi":"10.1176/appi.ajp.20260530","DOIUrl":"https://doi.org/10.1176/appi.ajp.20260530","url":null,"abstract":"","PeriodicalId":7656,"journal":{"name":"American Journal of Psychiatry","volume":"54 1","pages":""},"PeriodicalIF":17.7,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149020509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age-Associated Cognitive Deviations in Early-Onset Psychosis Patients and Their Siblings","authors":"Josephine Mollon,Nuria Lanzagorta,Samuel R. Mathias,Amanda L. Rodrigue,Emma E.M. Knowles,Maria Jalbrzikowski,Emma Deaso,Laura Cadavid,Jimena Unzueta Saavedra,Catherine Brownstein,Joseph Gonzalez-Heydrich,Patricia Zavaleta Ramírez,Emmanuel Sarmiento,Carlos Bustamante,Laura Almasy,Humberto Nicolini,David C. Glahn","doi":"10.1176/appi.ajp.20251082","DOIUrl":"https://doi.org/10.1176/appi.ajp.20251082","url":null,"abstract":"","PeriodicalId":7656,"journal":{"name":"American Journal of Psychiatry","volume":"26 1","pages":""},"PeriodicalIF":17.7,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149020510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implantable Neuromodulation Devices in Psychiatry: Human Fidelity and Implementation Challenges.","authors":"Gabriel Lázaro-Muñoz,Amanda R Merner","doi":"10.1176/appi.ajp.20251187","DOIUrl":"https://doi.org/10.1176/appi.ajp.20251187","url":null,"abstract":"","PeriodicalId":7656,"journal":{"name":"American Journal of Psychiatry","volume":"368 1","pages":"appiajp20251187"},"PeriodicalIF":17.7,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148400574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Prevalence of Obsessive-Compulsive and Related Disorders: A Systematic Review and Modeling Study.","authors":"Yi Deun Jeong,Yejun Son,Sangeon Jeon,Hanseul Cho,Seung Woo Ryuk,Yeona Jo,Guillaume Fond,Laurent Boyer,Lee Smith,Samuele Cortese,Paolo Fusar-Poli,Dong Keon Yon,Marco Solmi","doi":"10.1176/appi.ajp.20250944","DOIUrl":"https://doi.org/10.1176/appi.ajp.20250944","url":null,"abstract":"OBJECTIVEObsessive-compulsive disorder (OCD) is one of the common mental disorders globally. However, there are limited studies on the prevalence of OCD and four other disorders categorized under obsessive-compulsive and related disorders, namely, hoarding disorder, excoriation disorder, body dysmorphic disorder, and trichotillomania. The authors sought to fill the epidemiological gap in the literature.METHODSPubMed/MEDLINE, Embase, CINAHL, PsycINFO, and Google Scholar were systematically searched from inception to June 8, 2025. Studies representative of national or subnational general populations, with diagnoses based on DSM or ICD-10 criteria, were included. A Bayesian hierarchical linear mixed model was used to estimate the lifetime prevalence of OCD at the global, regional, and national levels, with estimates reported with 95% credible intervals. The authors examined the association between OCD prevalence and the Socio-demographic Index (SDI), and estimated age-specific point prevalence of OCD.RESULTSA total of 112 studies reporting prevalence rates for obsessive-compulsive and related disorders were included. The global lifetime Bayesian prevalence of OCD across all ages was estimated at 2.57% according to ICD-10 criteria, 3.10% according to DSM-III criteria, 2.28% according to DSM-IV criteria, and 3.21% according to DSM-5 criteria. Lifetime prevalence of OCD was negatively correlated with SDI, indicating lower prevalence estimates in countries with higher SDI. The age-specific prevalence of OCD increased sharply in the teen years and peaked in the late 20s to early 30s. Point prevalence ranged across studies from 0.98% to 5.81% for hoarding disorder, from 2.33% to 7.68% for excoriation disorder, from 0.44% to 15.21% for body dysmorphic disorder, and from 0.0% to 2.12% for trichotillomania.CONCLUSIONSThis study estimated the global prevalence of OCD according to diagnostic criteria, underscoring the role of diagnostic definitions in shaping epidemiological understanding.","PeriodicalId":7656,"journal":{"name":"American Journal of Psychiatry","volume":"260 1","pages":"appiajp20250944"},"PeriodicalIF":17.7,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148400572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment Patterns and Barriers to Care Among U.S. Adults With Co-Occurring Substance Use Disorder and Mental Illness.","authors":"Yiwei Lin,Haotian Li,Milap C Nahata,Chen Zhang,Olivia L Ramey,Ligang Liu","doi":"10.1176/appi.ajp.20251314","DOIUrl":"https://doi.org/10.1176/appi.ajp.20251314","url":null,"abstract":"OBJECTIVEThis study aimed to examine treatment patterns among U.S. adults with co-occurring substance use disorder (SUD) and mental illness, identify sociodemographic factors associated with receipt of treatment for both conditions, and characterize barriers to care.METHODSThe authors analyzed cross-sectional data from the 2021-2023 National Survey on Drug Use and Health. Adults age 18 years and older who met criteria for past-year SUD and either any mental illness or serious mental illness were included. The primary outcome was receipt of treatment for both conditions in the past year, and secondary outcomes included self-reported barriers to treatment. Weighted prevalence estimates and multivariable logistic regression models were used.RESULTSAmong adults with co-occurring SUD and any mental illness, receipt of treatment for both increased from 7.5% in 2021 to 16.9% in 2022 and 18.2% in 2023. Among adults with co-occurring SUD and serious mental illness, receipt of treatment for both increased from 12.3% in 2021 to 25.0% in 2022 and 25.6% in 2023. Female sex, older age, and poorer self-rated health were associated with higher odds of receiving treatment for both conditions. Non-White and uninsured adults had significantly lower odds. Less than 2% of untreated adults reported perceiving a need for and seeking treatment. Commonly reported barriers included treatment not being a priority, stigma, cost, limited access, and lack of readiness.CONCLUSIONSReceipt of both substance use treatment and mental health treatment remained low among U.S. adults with co-occurring disorders despite modest post-COVID-19 pandemic increases. Persistent disparities and barriers suggest a need for stronger parity enforcement, stable financing, and improved coordination across behavioral health services.","PeriodicalId":7656,"journal":{"name":"American Journal of Psychiatry","volume":"33 1","pages":"appiajp20251314"},"PeriodicalIF":17.7,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148400573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}