{"title":"Gene conversion and the evolution of gene families in mammals.","authors":"J C Schimenti","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"49 ","pages":"85-91"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18936441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Functional polymorphism in class I major histocompatibility complex genes.","authors":"P Parham","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"49 ","pages":"93-103"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18936442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Molecular evolution of physiological processes. Woods Hole, Massachusetts, 8-11 September 1993. Proceedings.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"49 ","pages":"1-283"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18939402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Profilins, ancient actin binding proteins with highly divergent primary structures.","authors":"T D Pollard, S Quirk","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"49 ","pages":"117-28"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18939404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using sequence homology to analyze the structure and function of voltage-gated ion channel proteins.","authors":"H R Guy, S R Durell","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Molecular modeling and mutagenesis analysis of voltage-gated channels have succeeded in identifying much of the topology of the proteins and in identifying which sequential segments are involved in functional mechanisms such as activation gating, inactivation gating, ion selectivity, and ligand binding. Efforts are currently underway to use these methods to model the protein structure and functional mechanisms more precisely. The experimental and theoretical efforts are dependent to a considerable extent upon information obtained by comparing homologous sequences. Although the fine details of models developed in this manner are unlikely to be as correct as models developed from x-ray crystallography and NMR, they still may contribute substantially to our understanding of the structure and function of these important proteins.</p>","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"49 ","pages":"197-212"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18531743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Monophyletic origin of animals: a shared ancestry with the fungi.","authors":"P O Wainright, D J Patterson, M L Sogin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"49 ","pages":"39-53"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18936438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Introns, the broken transposons.","authors":"A J Roger, P J Keeling, W F Doolittle","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"49 ","pages":"27-37"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18936435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The actin protein superfamily.","authors":"C Fyrberg, L Ryan, L McNally, M Kenton, E Fyrberg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"49 ","pages":"173-8"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18939409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transposable elements and the evolution of heterochromatin.","authors":"A C Spradling","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Drosophila P elements were shown to insert frequently into telomeric and centromeric heterochromatin, and to prefer a region associated with efficient copy number regulation. Upon excision, P elements frequently altered the number of repeats in a tandem array of heterochromatic sequences, by inducing unequal gene conversion. These studies suggest that a flux of transposable element insertions and excisions has the capacity to rapidly and nonrandomly modify heterochromatic sequences dispersed at multiple chromosomal sites. We propose that transposable elements maintain genomic heterochromatin in a state of dynamic equilibrium and drive its rapid evolution.</p>","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"49 ","pages":"69-83"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18936440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Function and biosynthesis of erythroid and nonerythroid anion exchangers.","authors":"S Ruetz, A E Lindsey, R R Kopito","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"48 ","pages":"193-200"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19486347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}