{"title":"[Sulfasalazine in the treatment of rheumatoid arthritis. A multicenter open study of 150 patients during 6 months].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One hundred and fifty patients with rheumatoid arthritis were given sulfasalazine in a daily dosage of 2 g during an open-label, multicenter, six-month trial. Improvements were apparent as early as four weeks after initiation of the drug. Improvements in clinical parameters and erythrocyte sedimentation rate were statistically significant. In the patients who remained on the study protocol, clinical and biological improvements continued over time and were more marked after six months. Overall clinical safety was satisfactory: 30 patients were withdrawn from the trial for adverse events, all of which resolved after discontinuation of the study drug. Most of these adverse events (93%) developed within two months of initiation of the drug, demonstrating the need for hematologic and hepatic tests at regular intervals during the first three months of sulfasalazine therapy. Thirty-four patients had not previously received maintenance therapy; in this subgroup, only one patient was withdrawn for ineffectiveness. In view of its favorable risk/benefit ratio and fast action, sulfasalazine may be a useful first-line drug in patients with rheumatoid arthritis.</p>","PeriodicalId":76478,"journal":{"name":"Revue du rhumatisme et des maladies osteo-articulaires","volume":"59 11","pages":"707-13"},"PeriodicalIF":0.0,"publicationDate":"1992-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12536306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Perrot, J M Ziza, P Khalifa, P Chazerain, J P Campagne, J L Le Quintrec
{"title":"[Persistent pain following discal sciatica: reflex sympathetic dystrophy, an unusual complication to be examined. Apropos of 4 cases].","authors":"S Perrot, J M Ziza, P Khalifa, P Chazerain, J P Campagne, J L Le Quintrec","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Four patients who developed unilateral reflex sympathetic dystrophy of a lower limb associated with a bout of sciatica due to lumbar disc herniation are reported herein. In two cases, reflex sympathetic dystrophy developed after resolution of the sciatica, whereas the two conditions were concomitant in the two other patients. In all four patients, the diagnosis of reflex sympathetic dystrophy was missed. Surgery to release the root was considered in two cases. The reflex sympathetic dystrophy resolved within 1 to 3 months in every case. In view of the incidences of these two conditions, their concomitant occurrence seems rare. To avoid unwarranted therapeutic procedures, reflex sympathetic dystrophy should be considered in patients with chronic painful manifestations accompanying root involvement.</p>","PeriodicalId":76478,"journal":{"name":"Revue du rhumatisme et des maladies osteo-articulaires","volume":"59 11","pages":"745-7"},"PeriodicalIF":0.0,"publicationDate":"1992-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12480966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T Billey, C Dromer, C Vedrenne, M Caulier, B Fournié
{"title":"[Parsonage-Turner syndrome complicated by sympathetic dystrophy syndrome with adhesive capsulitis of the shoulder. Apropos of 2 cases].","authors":"T Billey, C Dromer, C Vedrenne, M Caulier, B Fournié","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two typical cases of Parsonage-Turner syndrome with reflex sympathetic dystrophy syndrome and adhesive capsulitis of the shoulder are reported. The rarity of this combination is discussed.</p>","PeriodicalId":76478,"journal":{"name":"Revue du rhumatisme et des maladies osteo-articulaires","volume":"59 11","pages":"765-7"},"PeriodicalIF":0.0,"publicationDate":"1992-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12480971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P Gepner, A M Piette, J F Patrat, P Graveleau, A Chapman
{"title":"[Does arthritis due to varicella zoster virus exist?].","authors":"P Gepner, A M Piette, J F Patrat, P Graveleau, A Chapman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Occurrence of monoarthritis or oligoarthritis during the course of zoster is exceedingly rare (three previously reported cases). In the additional case reported herein, an immunocompetent female exhibited oligoarthritis (right shoulder followed by two metacarpophalangeal joints in her right hand) a few days before developing a typical zoster eruption in the ipsilateral upper limb. Pathogenesis of zoster-related arthritis is discussed. The most likely hypothesis is infection of the joint via the nerve supply rather than via the bloodstream. Evidence in support of this mechanism includes recovery of the virus from synovial fluid specimens in a previously published case.</p>","PeriodicalId":76478,"journal":{"name":"Revue du rhumatisme et des maladies osteo-articulaires","volume":"59 11","pages":"735-7"},"PeriodicalIF":0.0,"publicationDate":"1992-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12512528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F Eulry, X Chevalier, P Crozes, D Lechevalier, J Magnin, M Prudat, P Patoz, B Larget-Piet
{"title":"[Plasma lipids in reflex sympathetic dystrophy. A study apropos of 90 cases].","authors":"F Eulry, X Chevalier, P Crozes, D Lechevalier, J Magnin, M Prudat, P Patoz, B Larget-Piet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Plasma levels of cholesterol, triglyceride, HDL-cholesterol, and apolipoproteins A1 and B were assayed in ninety patients (sixty-four male and twenty-six female) with reflex sympathetic dystrophy and in ninety controls matched for age, sex, and body mass index (BMI). No significant differences were found between the two groups for the proportions of patients with increased plasma cholesterol levels (6.6% versus 4.4%) or increased plasma triglyceride levels (40% versus 30%), as defined by Turpin's age and sex-specific criteria, or for mean values of these parameters. In the 38 patients with reflex sympathetic dystrophy of less than 3.5 months duration, plasma triglyceride levels were significantly higher than in the 38 matched controls (1.24 + 0.57 g/l versus 1.02 +/- 0.91; p = 0.04). In patients (n = 52) with disease of more than four months duration (range 4-39), plasma triglyceride levels were similar in the two groups. Lipidemia was similar in patients and controls regardless of age, sex, topography of the disease, clinical manifestations, and whether or not the disease was due to an injury. This study, in contrast to previous reports, failed to disclose an association between reflex sympathetic dystrophy and hyperlipidemia. Transient hypertriglyceridemia may occur during the first 3 1/2 months of the disease as a result of initial immobilization.</p>","PeriodicalId":76478,"journal":{"name":"Revue du rhumatisme et des maladies osteo-articulaires","volume":"59 11","pages":"721-7"},"PeriodicalIF":0.0,"publicationDate":"1992-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12480371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Dermatopolymyositis and D-penicillamine: value of the search for anti-JO1 antibodies].","authors":"A C Koeger, F Oberlin, S Rozenberg, P Bourgeois","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76478,"journal":{"name":"Revue du rhumatisme et des maladies osteo-articulaires","volume":"59 11","pages":"774"},"PeriodicalIF":0.0,"publicationDate":"1992-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12480839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Crouzet, S Richard, G Pillet, B Muckensturm, A Srour, P Pradat
{"title":"[Meningeal melanocytoma or multiple pigmented meningioma of the spinal canal. Report of a case. Review of the literature].","authors":"J Crouzet, S Richard, G Pillet, B Muckensturm, A Srour, P Pradat","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a 64-year-old male with pain and weakness of the right lower limb, investigations disclosed a cervical tumor, several dorsal tumors, and tumoral infiltration of the lumbosacral area. Histological and, above all, immunohistochemical and ultrastructural features were suggestive of meningeal melanocytoma. Before the use of immunohistochemical and electron microscopy techniques, meningeal melanocytoma was designated by the term pigmented meningioma because its histological features bear some resemblance to those of meningioma. However, only a few cases of meningeal melanocytoma have been documented by immunohistochemistry and electron microscopy. Previously reported patients with meningeal melanocytoma had solitary tumors. In contrast, a review of the literature showed that multiple intraspinal or intraspinal and intracranial meningiomas are not exceptional, although meningiomatous infiltration is considerably less frequent. Treatment of such cases rests on surgery, radiotherapy, and chemoimmunotherapy.</p>","PeriodicalId":76478,"journal":{"name":"Revue du rhumatisme et des maladies osteo-articulaires","volume":"59 11","pages":"738-43"},"PeriodicalIF":0.0,"publicationDate":"1992-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12480965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B de Wazieres, D Wendling, T Fest, G Morin, J L Dupond
{"title":"[Bone and visceral manifestations of lipoatrophic diabetes. Apropos of a case].","authors":"B de Wazieres, D Wendling, T Fest, G Morin, J L Dupond","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lipoatrophic diabetes, known by pediatricians as Lawrence-Seip disease or Berardinelli lipodystrophy syndrome, is an infrequent condition of which approximately one hundred cases have been published to date. A case in a 24-year-old female with a fifteen-year follow-up is reported. Manifestations included acanthosis nigricans, generalized lipoatrophy, hirsutism, muscle hypertrophy, and intellectual impairment. Biologic tests revealed insulin-resistant diabetes mellitus with major diet-dependent type V hypertriglyceridemia. The patient had nephrotic syndrome (focal and segmental endocapillary proliferative glomerulonephritis without dense deposits). Phosphorus and calcium determinations were normal, as were the endocrinologic tests. Roentgenograms of the bones disclosed increased density of axial bones and large epiphyseal defects with increased bone density as determined by osteodensitometric studies. The bone manifestations of this syndrome have been documented but are often overshadowed by the severe metabolic alterations.</p>","PeriodicalId":76478,"journal":{"name":"Revue du rhumatisme et des maladies osteo-articulaires","volume":"59 11","pages":"761-4"},"PeriodicalIF":0.0,"publicationDate":"1992-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12480970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Coccygodynia: value of dynamic lateral x-ray films in sitting position].","authors":"J Y Maigne, S Guedj, B Fautrel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In coccygodynia, pain is most severe in the sitting position. This prompted a study comparing lateral roentgenograms of the coccyx taken with the patient lying on the side. In this prospective study, eight of 30 patients had posterior subdislocation of the coccyx which caused pain and was visible only on the films taken in the sitting position.</p>","PeriodicalId":76478,"journal":{"name":"Revue du rhumatisme et des maladies osteo-articulaires","volume":"59 11","pages":"728-31"},"PeriodicalIF":0.0,"publicationDate":"1992-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12480963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Comparative efficacy of ketoprofen related to the route of administration (intramuscular or per os). A double-blind study versus placebo in rheumatoid arthritis].","authors":"M Dougados, V Listrat, L Duchesne, B Amor","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Evidence of the analgesic effects of nonsteroidal antiinflammatory drugs in human diseases is easy to collect. However, demonstration of differences in the activity of NSAIDs according to the route of administration is considerably more difficult. Forty patients with rheumatoid arthritis were given either one intramuscular injection of 100 mg ketoprofen with two placebo capsules or one intramuscular injection of placebo with two 50 mg ketoprofen capsules. Analysis of changes in pain severity over the six-hour study period failed to disclose any statistically significant differences between the two groups. However, time to peak effectiveness (Tmax) was significantly shorter with the intramuscular route (194 +/- 118 minutes) than with the oral route (276 +/- 111 minutes) (p = 0.029). Although intramuscular NSAID therapy is rarely warranted in RA patients, these findings suggest that RA may serve as a clinical model for evaluating the effectiveness of a NSAID according to the route of administration.</p>","PeriodicalId":76478,"journal":{"name":"Revue du rhumatisme et des maladies osteo-articulaires","volume":"59 11","pages":"769-73"},"PeriodicalIF":0.0,"publicationDate":"1992-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12480838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}