{"title":"[Treatment of obesity in patients with changes of carbohydrate metabolism].","authors":"J Zurro Hernandez, H Romero Fernandez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The combination of dextroamphetamines, biguanides and choleretics seems to be a good therapy for obese patients with carbohydrate intolerance, since the ponderary curve and carbohydrate tolerance improve. Results obtained are statistically significant.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"22 128","pages":"131-59"},"PeriodicalIF":0.0,"publicationDate":"1975-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12323577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Sensitivity of the thyroideal cell to external irradiation].","authors":"A E Lanaro, A Bsoch, Z Frias","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Evaluation of the variation in thyroid function utilizing 131I uptake in patients exposed to external radiation to the thyroid gland for reasons not related to this gland. The study was initiated with 54 patients who were examined prior to irradiation. They received an average dose of 5.650 r to the gland in a period of 5-6 weeks. Upon completion of the radiation therapy an abrupt drop in the uptake values occurred reaching the hypofunction range and one month later there is a recovery to 80% of the initial level and the value remains stable up to one year. Followed, year after year, a progressive reduction occurs in the uptake value up to a period of 6 years when the 2 surviving patients have returned to the hypothyroid level. The number of patients during the latter years of the study is too low to be statistically significant. The usefulness of this observation is discussed and a comparison is made of the external irradiation effects and the effects of 131I therapy.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"22 128","pages":"105-18"},"PeriodicalIF":0.0,"publicationDate":"1975-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12323575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J M Palacios Mateos, P Rodrĭguez Poyo-Guerrero, J Salmeron, I Pato, T Reymunde
{"title":"[Occurrence and clinical characteristics of thyroid cancer in a hospital population].","authors":"J M Palacios Mateos, P Rodrĭguez Poyo-Guerrero, J Salmeron, I Pato, T Reymunde","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors reviewed 83.250 clinical histories from the files of a hospital, among which they found 49 thyroid carcinomas whose characteristics they study. It is interesting to note the great incidence of papilliferous carcinoma (53 per cent of cases); a most marked incidence of the condition in female patients; the slight difference in the age of the patients with all types of carcinoma; and, above all, the atypicity of the onset symptoms in a large number of cases (28 per cent). According to these data, the authors suggest that it is advisable to bare in mind the possibility of the presence of thyroid carcinoma in patients with such unmatched pictures as suppurative thyroiditis, sciatica or cervical adenopathy, with absence of goiter, etc.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"22 128","pages":"121-9"},"PeriodicalIF":0.0,"publicationDate":"1975-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12323576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Osmosensitive neurons in the retrochiasmatic area of the hypothalamus. An ultrastructural study].","authors":"M Lafarga, G Palacios","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An ultrastructural study has been conducted of the response of rat retrochiasmatic area neurons to an intraperitoneal injection of hypertonic sodium chloride. The formation of numerous communications between nuclear envelope and the granular endoplasmic reticulum (GER) is seen as a response of these neurons to the osmotic stimulus. Some of the GER cisterns may establish contact with the neuronal membrane. The quantity of polyribosomal rosettes increases, especially in the nuclear cytoplasmic infoldings. These results are interpreted as a change in the programmed activity of synthesis of these neurons. Previous electrophysiologic studies appear to demonstrate the possibility of these neurons being osmoreceptors. These ultrastructural observations seem to confirm this hypothesis.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"22 127","pages":"9-21"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12323579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J A Tresguerres, M D Fernández, M C Fernández-Galaz, A Oriol Bosch
{"title":"[Radioimmunoanalysis of plasma testosterone].","authors":"J A Tresguerres, M D Fernández, M C Fernández-Galaz, A Oriol Bosch","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A simple radioimmunoassay procedure for the determination of testosterone concentration in plasma is described. Small amounts of plasma, 0,5 ml for males and 1 ml for females, are extracted with diethyl ether. Recoveries for the extraction are obtained by the addition of labelled tesosterone. The radioimmunoassay is performed directly on the extracts without further purification. Separation of the free from the antibodie bound testosterone is achieved with dextran coated charocoal. Under the used conditions, the calibration curve covers a range between 0,5 and 1,5 ng per sample. Reproducibility is acceptable with a coefficient of variation of 7%. The normal values are slightly higher than those obtained with methods using some purification step of the extract before the assay but due to its simplicity the described method is a suitable one for clinical purposes.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"22 127","pages":"23-41"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12323874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Clinical evaluation of glipizide. Results of a multicentric study in Spain].","authors":"V M Cerdeño, A G Passigli, J Calvet, J Soler","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this study, with the evaluation of 621 diabetics under treatment, it is shown that glipizide is a potent oral sulfonilurea which controlled satisfactorily the blood sugar levels in 83,5% of diabetics without previous treatment, 67% of the cases with positive response to previous anti-diabetic therapy and 51,3% of the patients that had not responded to previous treatments. The most frecuently used dosage was 5 mg daily, with a minimum of 2,5 mg and a maximum of 30 mg. Tolerance and safety observed was excellent.</p>","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"22 127","pages":"43-60"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12323578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Determination of urinary testosterone by gas chromatography].","authors":"A Lorenzo, M C Ruiz González, A Oriol Bosch","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"21 126","pages":"533-51"},"PeriodicalIF":0.0,"publicationDate":"1974-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15543565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Mammary hypertrophy and menorrhagias in a patient with primary hypothyroidism].","authors":"A Ferrández Longas","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"21 126","pages":"553-8, 561-5"},"PeriodicalIF":0.0,"publicationDate":"1974-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15543569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Control of the synthesis of ribonucleic acid: mechanism of hormonal regulation].","authors":"S Castells","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"21 126","pages":"513-31"},"PeriodicalIF":0.0,"publicationDate":"1974-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15479606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Clinical study with glypentide, new sulfonylurea hypoglycemic agent].","authors":"J M Pou Torelló, J M Vilaclara","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76462,"journal":{"name":"Revista iberica de endocrinologia","volume":"21 125","pages":"427-30, 433-8, 441-2 passim"},"PeriodicalIF":0.0,"publicationDate":"1974-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15709944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}