Reumatizam最新文献_第10页

[THE IMPORTANCE OF TRANSITION IN RHEUMATOLOGY]. [风湿病学过渡的重要性]。

Reumatizam Pub Date : 2016-01-01

Mandica Vidović, Miroslav Mayer

引用次数: 0

Late onset rheumatoid arthritis an observational study. 晚发性类风湿关节炎:观察性研究。

Reumatizam Pub Date : 2016-01-01

Sylejman Rexhepi, Mjellma Rexhepi, Vjollca Sahatçiu-Meka, Blerta Rexhepi, Elton Bahtiri, Vigan Mahmutaj

{"title":"Late onset rheumatoid arthritis an observational study.","authors":"Sylejman Rexhepi, Mjellma Rexhepi, Vjollca Sahatçiu-Meka, Blerta Rexhepi, Elton Bahtiri, Vigan Mahmutaj","doi":"","DOIUrl":"","url":null,"abstract":"Rheumatoid arthritis (RA) may have an onset at older age. The onset of the disease at the age of 60 and\u0000over is called late-onset rheumatoid arthritis (LORA). The aim of this study was to analyze the clinical, laboratory,\u0000radiological, and treatment characteristics of patients with LORA compared to those with early-onset RA (EaORA),\u0000provided that all the patients had an approximately equal duration of the disease. This is an observational single-center\u0000study, which involved 120 patients with an established diagnosis of RA, of which 60 patients had LORA, and 60 patients\u0000EaORA. The disease activity, measured by the Disease Activity Score 28 (DAS28-ESR), was significantly higher in the\u0000LORA group compared to the EaORA group (p<0.05). Significantly more patients with LORA had involvement of the\u0000shoulders (LORA vs. EaORA, 30% vs. 15%; p <0.05) and knees (LORA vs. EaORA, 46.7% vs. 16.7%; p <0.05). Radiological\u0000erosive changes were significantly more frequent in the LORA group in comparison with EaORA (p <0.05).\u0000There was no difference between the groups regarding rheumatoid factor (RF) positivity (p>0.05), while the number\u0000of patients positive for anti-citrullinated protein antibody (ACPA) was signifi cantly greater in the EaORA group\u0000(p<0.05). The values of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were significantly higher\u0000in the LORA than in the EaORA group. Hemoglobin levels were lower in the LORA group (11.96±1.64 g/dL) than in\u0000the EaORA group (12.18±1.56 g/dL). The most used disease-modifying antirheumatic drugs (DMARDs) were methotrexate\u0000and sulfasalazine, while biological drugs were not used.\u0000In conclusion, based on the results of our study, LORA has some features that distinguish it from EaORA, such as\u0000higher disease activity, more frequent involvement of large joints, and more pronounced structural damage. This\u0000should be taken in account in clinical practice, especially regarding treatment choices.","PeriodicalId":76426,"journal":{"name":"Reumatizam","volume":"63 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35976052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[VASCULITIDES IN CHILDHOOD]. [儿童血管疾病]。

Reumatizam Pub Date : 2016-01-01

Marija Jelušić, Marijan Frković

引用次数: 0

EFFECT OF DISEASE-MODIFYING ANTIRHEUMATIC DRUGS ON THE VALUES OF APOLIPOPROTEIN A-1 AND ACUTE PHASE REACTANTS IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS. 改善疾病的抗风湿药物对活动性类风湿关节炎患者载脂蛋白a-1和急性期反应物的影响

Reumatizam Pub Date : 2016-01-01

Husni Ismaili, Suada Mulić-Bačić, Necmedin Karemani, Nikola Orovčanec

{"title":"EFFECT OF DISEASE-MODIFYING ANTIRHEUMATIC DRUGS ON THE VALUES OF APOLIPOPROTEIN A-1 AND ACUTE PHASE REACTANTS IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS.","authors":"Husni Ismaili, Suada Mulić-Bačić, Necmedin Karemani, Nikola Orovčanec","doi":"","DOIUrl":"","url":null,"abstract":"In this observational study we examined the impact of disease-modifying antirheumatic drugs (DMARDS) on the\u0000disease activity as well as the values of acute phase reactants and the apolipoprotein A1 (Apo A1) in patients with active\u0000rheumatoid arthritis (RA). Eighty patients with active RA and newly discovered RA patients who meet the American\u0000Rheumatology Association (ARA) 1987 revised criteria were treated with disease modifying anti-rheumatic drugs –\u0000DMARDs according to the standard protocol of everyday clinical practice. At 6 and 12 months of treatment the patients\u0000achieved a signifi cant decrease in the disease activity score 28 (DAS28), C-reactive protein (CRP), and erythrocyte\u0000sedimentation rate (ESR) values. On the other hand, the levels of Apo A-1, which were low at baseline, were signifi -\u0000cantly higher. In conclusion, the use of DMARDs in patients with RA reduced disease activity and infl ammation, but\u0000also had a benefi cial eff ect in increasing the levels of atheroprotective Apo A-1 lipoprotein, which can reduce CV risks\u0000in these patients.","PeriodicalId":76426,"journal":{"name":"Reumatizam","volume":"63 2","pages":"9-14"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35982377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PERICARDIAL FEATURES OF IN-HOSPITAL RHEUMATOLOGY PATIENTS: AN OBSERVATIONAL STUDY. 住院风湿病患者的心包特征:一项观察性研究

Reumatizam Pub Date : 2016-01-01

Aurora Bakalli, Mjellma Rexhepi, Blerta Rexhepi, Dardan Koçinaj

{"title":"PERICARDIAL FEATURES OF IN-HOSPITAL RHEUMATOLOGY PATIENTS: AN OBSERVATIONAL STUDY.","authors":"Aurora Bakalli, Mjellma Rexhepi, Blerta Rexhepi, Dardan Koçinaj","doi":"","DOIUrl":"","url":null,"abstract":"Rheumatic disorders can be associated with pericarditis, but severe forms of pericarditis are rare. The aim of this\u0000observational study was to evaluate pericardial features in patients with different rheumatic diseases. Thirty-five\u0000patients hospitalized at the Clinic of Rheumatology, University Clinical Center of Kosovo, from October 1 to October\u000021, 2014 were included in the study. Demographic data, history, laboratory, ECG, and echocardiography data, with\u0000special emphasis on the analysis of the pericardium, were obtained from each patient. Echocardiography was especially\u0000focused on the amount of pericardial fluid and pericardial thickness in the posterior wall of the heart.\u0000Mean patient age was 51.5 ± 13.8 years. 65.7% of the patients were women. Out of the patients that we analyzed,\u000088.6% had an inflammatory rheumatologic disease. 11.3% of the patients had mild symptoms, in 68.7% the symptoms\u0000were moderate, and in 20% severe. In all patients, pericardial hyperechogenicity was marked, with a mean pericardial\u0000thickness of 4.68 ± 1.66 mm. Pericardial effusion in a small amount was present in 57.1% of patients, with a mean\u0000pericardial fluid amount of 3.3 ± 1.9 mm. The severity of rheumatic disease had a positive and significant correlation\u0000with the presence of pericardial effusion (r= 0.29, p=0.04) and its amount (r= 0.28, p=0.05). The patients had not been\u0000aware of the pericardial involvement and did not have any clinical symptoms.\u0000In conclusion, in this short-term small observational study pericardial changes were a frequent finding in the\u0000rheumatology patients. In general, the pericarditis was subclinical and with small amounts of effusion. The disease\u0000activity of rheumatic disorders can be associated with pericarditis. Further studies with larger samples of patients and\u0000of longer duration are needed to further explore this issue.","PeriodicalId":76426,"journal":{"name":"Reumatizam","volume":"63 2","pages":"21-5"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35982382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Epidemiology of inflammatory rheumatic diseases]. [风湿病的流行病学]。