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Psychopharmacology communications最新文献

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Attentuation of precipitated abstinence in methadone-dependent rats by delta9-THC. δ 9-四氢大麻酚对美沙酮依赖大鼠沉淀性戒断的减弱作用。
Psychopharmacology communications Pub Date : 1976-01-01
S M Deikel, B Carder
{"title":"Attentuation of precipitated abstinence in methadone-dependent rats by delta9-THC.","authors":"S M Deikel, B Carder","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76387,"journal":{"name":"Psychopharmacology communications","volume":"2 1","pages":"61-5"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12142109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discriminative response control by psychomotor stimulants. 精神运动兴奋剂的辨别反应控制。
Psychopharmacology communications Pub Date : 1976-01-01
P B Silverman, B T Ho
{"title":"Discriminative response control by psychomotor stimulants.","authors":"P B Silverman, B T Ho","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Psychomotor stimulants are capable of controlling discriminative responding in rats. Evidence suggests that response control is central, of a fairly specific nature, and dependent on intact dopaminergic functions.</p>","PeriodicalId":76387,"journal":{"name":"Psychopharmacology communications","volume":"2 4","pages":"331-7"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11234610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discriminable stimuli produced by alcohol and other CNS depressants. 酒精和其他中枢神经系统抑制剂产生的可辨别的刺激。
Psychopharmacology communications Pub Date : 1976-01-01
H Barry, E C Krimmer
{"title":"Discriminable stimuli produced by alcohol and other CNS depressants.","authors":"H Barry,&nbsp;E C Krimmer","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76387,"journal":{"name":"Psychopharmacology communications","volume":"2 4","pages":"323-6"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12179357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discriminable stimuli produced by hallucinogens. 由致幻剂产生的可辨别的刺激。
Psychopharmacology communications Pub Date : 1976-01-01
D M Kuhn, F J White, J B Appel
{"title":"Discriminable stimuli produced by hallucinogens.","authors":"D M Kuhn,&nbsp;F J White,&nbsp;J B Appel","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76387,"journal":{"name":"Psychopharmacology communications","volume":"2 4","pages":"345-8"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12179358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Discriminable stimuli produced by marihuana constituents. 大麻成分产生的可辨别的刺激。
Psychopharmacology communications Pub Date : 1976-01-01 DOI: 10.1007/978-1-4684-3090-5_8
E. C. Krimmer, H. Barry
{"title":"Discriminable stimuli produced by marihuana constituents.","authors":"E. C. Krimmer, H. Barry","doi":"10.1007/978-1-4684-3090-5_8","DOIUrl":"https://doi.org/10.1007/978-1-4684-3090-5_8","url":null,"abstract":"","PeriodicalId":76387,"journal":{"name":"Psychopharmacology communications","volume":"70 1","pages":"319-22"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51016893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Discriminable stimuli produced by narcotic analgesics. 麻醉性镇痛药产生的可辨别的刺激。
Psychopharmacology communications Pub Date : 1976-01-01
H Lal, G Gianutsos
{"title":"Discriminable stimuli produced by narcotic analgesics.","authors":"H Lal,&nbsp;G Gianutsos","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76387,"journal":{"name":"Psychopharmacology communications","volume":"2 4","pages":"311-4"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11234609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Free and conjugated dihydroxyphenylacetic acid: effect of alterations in impulse flow in rat neostriatum and frontal cortex. 游离和共轭二羟基苯乙酸:大鼠新纹状体和额叶皮层冲动流改变的影响。
Psychopharmacology communications Pub Date : 1976-01-01
M A Elchisak, L C Murrin, R H Roth, J W Maas
{"title":"Free and conjugated dihydroxyphenylacetic acid: effect of alterations in impulse flow in rat neostriatum and frontal cortex.","authors":"M A Elchisak,&nbsp;L C Murrin,&nbsp;R H Roth,&nbsp;J W Maas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Stimulation of the nigro-neostriatal dopamine pathway results in an accumulation of both free and conjugated dihydroxy-phenylacetic acid (DOPAC) in the rat neostriatum. Drugs which have previously been shown to alter impulse flow in central dopaminergic neurons also produce predictable changes in the levels of both free and conjugated DOPAC in both the neostriatum and, in most cases, in the frontal cortex. Drugs such as the antipsychotics which increase impulse flow in the nigro-neostriatal dopamine neurons increase both free and conjugated DOPAC levels in both the neostriatum and frontal cortex. Drugs which reduce impulse flow, such as d-amphetamine and apomorphine, cause a reduction in free DOPAC in both the neostriatum and frontal cortex but reduce DOPAC conjugate only in the neostriatum. Pargyline, a monoamine oxidase inhibitor, causes an extensive depletion of free and conjugated DOPAC in both the striatum and frontal cortex, indicating that these metabolites are rapidly cleared from both of these brain areas.</p>","PeriodicalId":76387,"journal":{"name":"Psychopharmacology communications","volume":"2 5-6","pages":"411-20"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11409718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of undrugged partners on scopolamine-induced changes in activity and sociability. 未接受治疗的伴侣对东莨菪碱诱导的活动和社交能力变化的影响。
Psychopharmacology communications Pub Date : 1976-01-01
W J Stewart
{"title":"Effects of undrugged partners on scopolamine-induced changes in activity and sociability.","authors":"W J Stewart","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One group of 6 rats was injected with saline, one with 1.0 mg/Kg scopolamine (D/D) and two others had half the members in each injected with saline and half with scopolamine (S/D). Each was tested in a 36 X 36 in. open field for 10 min. The frequency of ambulation, rearing, social contacts, and the shortest and perimeter distances between rats were found. The presence of the partners in the S/D groups eliminated most of the scopolamine-induced changes found in the D/D group, showing that the nature of the social environment affects drug-induced changes in activity and sociability.</p>","PeriodicalId":76387,"journal":{"name":"Psychopharmacology communications","volume":"2 2","pages":"131-9"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12162408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacokinetics of lithium in human plasma and erythrocytes. 锂在人血浆和红细胞中的药代动力学。
Psychopharmacology communications Pub Date : 1976-01-01
R I Poust, A G Mallinger, J Mallinger, J M Himmelhoch, I Hanin
{"title":"Pharmacokinetics of lithium in human plasma and erythrocytes.","authors":"R I Poust,&nbsp;A G Mallinger,&nbsp;J Mallinger,&nbsp;J M Himmelhoch,&nbsp;I Hanin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The time course of lithium concentration in plasma and RBCs was measured in normal adult males following administration of single and multiple doses of lithium carbonate. From the single dose profiles, it was determined that lithium distribution between plasma and RBCs is not a simple partitioning phenomenon. The single dose time course measurements in both blood components were fit to a two compartment pharmacokinetic model in which the plasma was representative of the central compartment and the RBCs were representative of the tissue compartment. The importance of correction for trapped plasma volume in studies measuring lithium RBC kinetics was emphasized. In this study it was also demonstrated that one can accurately predict plasma and RBC lithium concentrations which are observed following multiple dosing, on the basis of single dose parameters obtained in the same subject.</p>","PeriodicalId":76387,"journal":{"name":"Psychopharmacology communications","volume":"2 2","pages":"91-103"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12162409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Suppression of amphetamine-induced hypothermia by the neutral amino acid valine. 中性氨基酸缬氨酸抑制安非他明诱导的低温。
Psychopharmacology communications Pub Date : 1976-01-01
H J Chiel, R J Wurtman
{"title":"Suppression of amphetamine-induced hypothermia by the neutral amino acid valine.","authors":"H J Chiel,&nbsp;R J Wurtman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pretreatment with valine (0.5-2.0 mmoles/kg) can suppress the hypothermic response of rats placed in a 4degreesC environment and given d-amphetamine sulfate (5 or 10 mg/kg). The amino acid was most effective when given 30 minutes before amphetamine administration, at which time it also significantly lowered brain tyrosine concentration (and, presumably, suppressed catecholamine synthesis). Because dopaminergic neurons mediate the hypothermic response to amphetamine and because amphetamine's ability to produce hypothermia requires, in part, the release of newly synthesized dopamine, these observed effects of valine pretreatment support the hypothesis that treatments which alter precursor (tyrosine) availability also affect brain catecholamine synthesis.</p>","PeriodicalId":76387,"journal":{"name":"Psychopharmacology communications","volume":"2 3","pages":"207-17"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12179349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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