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Acute Lupus Erythematosus 急性红斑狼疮
Proceedings of the Royal Society of Medicine Pub Date : 2018-12-16 DOI: 10.1007/springerreference_40157
Angel A. Justiz Vaillant, Matthew Varacallo, S. Cassaro, Joseph Lee, Tanya Egodage
{"title":"Acute Lupus Erythematosus","authors":"Angel A. Justiz Vaillant, Matthew Varacallo, S. Cassaro, Joseph Lee, Tanya Egodage","doi":"10.1007/springerreference_40157","DOIUrl":"https://doi.org/10.1007/springerreference_40157","url":null,"abstract":"","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52960333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cicatricial Alopecia 瘢痕性脱发
Proceedings of the Royal Society of Medicine Pub Date : 2018-10-31 DOI: 10.5772/intechopen.78971
Qing Yang, W. Dou, P. Xue, Xianjie Ma, Xianhui Zeng, Lei Wang, Chiyu Jia
{"title":"Cicatricial Alopecia","authors":"Qing Yang, W. Dou, P. Xue, Xianjie Ma, Xianhui Zeng, Lei Wang, Chiyu Jia","doi":"10.5772/intechopen.78971","DOIUrl":"https://doi.org/10.5772/intechopen.78971","url":null,"abstract":"Cicatricial alopecia represents a group of disorders sharing a final pathway of destruction followed by replacement with fibrous tissue of the hair follicle unit. Cicatricial alopecia is classified into two categories, namely primary cicatricial alopecia, in which the hair follicle is the sole target of a progressive inflammatory process in a group of diverse skin or sys temic diseases, and secondary cicatricial alopecia, referring to the hair follicle destruction as a result of a nonspecific disruption of the dermis. Permanent hair loss may also occur in the late phases of some nonscarring alopecias that are called “biphasic alopecias.” Based on the pathological characteristics, the lesions of primary cicatricial alopecia are divided into lymphocyte-predominant subgroup, neutrophil-predominant subgroup, or mixed subgroup. In principle, the primary goal of the treatment aims to attenuate the progres sion of the inflammatory and the scarring processes at the earliest phase of the disease. In clinical practice, the lymphocyte-predominant lesions are treated with immunosuppres sive agents, whereas the neutrophil-predominant lesions are treated with antimicrobials or dapsone. As the efficacy of medication treatment against the cicatricial alopecia varies significantly, autologous hair transplantation is recommended to patients who have a relatively stable primary or a secondary cicatricial alopecia. replace the follicles or may diffusely involve the dermis, depending on the extent of inflammation. Scattered naked hairshaft granulomas are also seen in later stages.","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5772/intechopen.78971","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71002888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital heart disease 先天性心脏病
Proceedings of the Royal Society of Medicine Pub Date : 2018-03-29 DOI: 10.4324/9780429462450-10
D. Paladini, P. Volpe
{"title":"Congenital heart disease","authors":"D. Paladini, P. Volpe","doi":"10.4324/9780429462450-10","DOIUrl":"https://doi.org/10.4324/9780429462450-10","url":null,"abstract":"The fetal heart starts as a tube which folds and fuses in a complex dance that results in a muscular pump with four chambers and four valves. It is not surprising that small errors in development can lead to a wide variety of structural abnormalities in the 4 chambers, the 4 heart valves, the veins and great arteries. Most common heart defects, such as holes between the chambers (atrial septal defect, ventricular septal defect) and even more complex conditions such as transposition of the great arteries and tetralogy of Fallot, can be successfully managed after birth.","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"117 1 1","pages":"164-249"},"PeriodicalIF":0.0,"publicationDate":"2018-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70615803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic Potential of Curcumin for the Treatment of Brain Tumors. 姜黄素治疗脑肿瘤的潜力。
Proceedings of the Royal Society of Medicine Pub Date : 2016-01-01 Epub Date: 2016-10-11 DOI: 10.1155/2016/9324085
Neil V Klinger, Sandeep Mittal
{"title":"Therapeutic Potential of Curcumin for the Treatment of Brain Tumors.","authors":"Neil V Klinger, Sandeep Mittal","doi":"10.1155/2016/9324085","DOIUrl":"10.1155/2016/9324085","url":null,"abstract":"<p><p>Brain malignancies currently carry a poor prognosis despite the current multimodal standard of care that includes surgical resection and adjuvant chemotherapy and radiation. As new therapies are desperately needed, naturally occurring chemical compounds have been studied for their potential chemotherapeutic benefits and low toxicity profile. Curcumin, found in the rhizome of turmeric, has extensive therapeutic promise via its antioxidant, anti-inflammatory, and antiproliferative properties. Preclinical <i>in vitro</i> and <i>in vivo</i> data have shown it to be an effective treatment for brain tumors including glioblastoma multiforme. These effects are potentiated by curcumin's ability to induce G2/M cell cycle arrest, activation of apoptotic pathways, induction of autophagy, disruption of molecular signaling, inhibition of invasion, and metastasis and by increasing the efficacy of existing chemotherapeutics. Further, clinical data suggest that it has low toxicity in humans even at large doses. Curcumin is a promising nutraceutical compound that should be evaluated in clinical trials for the treatment of human brain tumors.</p>","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"64 1","pages":"9324085"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86941548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Poikiloderma of Civatte 西瓦特普氏病
Proceedings of the Royal Society of Medicine Pub Date : 2013-04-05 DOI: 10.7241/OURD.20132.43
U. Adaskevich, M. A. Katina, Valeryia A. Miadzelets
{"title":"Poikiloderma of Civatte","authors":"U. Adaskevich, M. A. Katina, Valeryia A. Miadzelets","doi":"10.7241/OURD.20132.43","DOIUrl":"https://doi.org/10.7241/OURD.20132.43","url":null,"abstract":"This clinical entity is not uncommon in Romania, especially in spring and summer,(but also during winter, for whose who are very fond of sky), most frequently diagnosed in fair-skin women over 40 years old, on a genetic background, after sun exposure (varying from minutes to hours), with a great cosmetic and physiological impact on social life. It is still a problem for dermatologists, not mainly for diagnosis but for therapy. It is an easy clinical diagnosis, although many other dyspigmentations must be ruled out (see classification).","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"45 1","pages":"185-187"},"PeriodicalIF":0.0,"publicationDate":"2013-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.7241/OURD.20132.43","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71382407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Jan Evangelista Purkynĕ, Czech scientist and patriot (1787-1869). 捷克科学家、爱国者扬·伊万杰利斯塔·普金尼(1787-1869)。
Proceedings of the Royal Society of Medicine Pub Date : 2012-05-05 DOI: 10.2307/40115756
H. J. John
{"title":"Jan Evangelista Purkynĕ, Czech scientist and patriot (1787-1869).","authors":"H. J. John","doi":"10.2307/40115756","DOIUrl":"https://doi.org/10.2307/40115756","url":null,"abstract":"","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"46 11 1","pages":"933-40"},"PeriodicalIF":0.0,"publicationDate":"2012-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2307/40115756","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68798023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Telangiectasia macularis eruptiva perstans 持久性发疹性斑状毛细血管扩张症
Proceedings of the Royal Society of Medicine Pub Date : 2011-04-01 DOI: 10.1016/j.jaad.2010.09.559
A. Acosta, R. Caruso, L. Dufrechou, Valeria Pomiés, M. Álvarez, Pilar Beltramo, G. M. SALMENTóN, M. Martínez
{"title":"Telangiectasia macularis eruptiva perstans","authors":"A. Acosta, R. Caruso, L. Dufrechou, Valeria Pomiés, M. Álvarez, Pilar Beltramo, G. M. SALMENTóN, M. Martínez","doi":"10.1016/j.jaad.2010.09.559","DOIUrl":"https://doi.org/10.1016/j.jaad.2010.09.559","url":null,"abstract":"","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"9 1","pages":"27-30"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jaad.2010.09.559","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54784702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case for Diagnosis. 病例诊断。
Proceedings of the Royal Society of Medicine Pub Date : 2007-01-01 DOI: 10.1093/milmed/142.6.434
G. Dawson
{"title":"Case for Diagnosis.","authors":"G. Dawson","doi":"10.1093/milmed/142.6.434","DOIUrl":"https://doi.org/10.1093/milmed/142.6.434","url":null,"abstract":"THE patient, a young woman, aged 33, of healthy appearance, had a peculiar condition of the extremities which began about six years ago on the palms of the hands and soles of the feet, where it remained limited for nearly two years. Since then it gradually extended up to the middle of the forearms and legs, being fairly well demarcated from the sound skin. It was of a brownish colour, and the numerous lines which intersected one another, as well as the roughness that was present, gave it the appearance of crocodile leather. There was, however, no appreciable thickening, no evidence of the follicles being involved, and no itching. Besides this condition there were patches of a psoriatic-looking eruption on the patelle and elbows. The eruption, which had never been m-ioist and was of a remarkably uniform appearance, did not appear to correspond to any described condition.","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"4 Dermatol Sect 1","pages":"102"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/milmed/142.6.434","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61000987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mikulicz's disease 米古利兹病
Proceedings of the Royal Society of Medicine Pub Date : 2004-01-01 DOI: 10.1007/3-540-29662-X_1841
L. Moreland
{"title":"Mikulicz's disease","authors":"L. Moreland","doi":"10.1007/3-540-29662-X_1841","DOIUrl":"https://doi.org/10.1007/3-540-29662-X_1841","url":null,"abstract":"","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"1 1","pages":"592-592"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51528398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subarachnoid Haemorrhage. 蛛网膜下腔出血。
Proceedings of the Royal Society of Medicine Pub Date : 1998-03-01 DOI: 10.1007/bf03285593
E. Cockayne
{"title":"Subarachnoid Haemorrhage.","authors":"E. Cockayne","doi":"10.1007/bf03285593","DOIUrl":"https://doi.org/10.1007/bf03285593","url":null,"abstract":"","PeriodicalId":76359,"journal":{"name":"Proceedings of the Royal Society of Medicine","volume":"32 9 1","pages":"1173"},"PeriodicalIF":0.0,"publicationDate":"1998-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/bf03285593","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52352682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
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