Problemy medycyny wieku rozwojowego最新文献

{"title":"[Ultrasonographic picture of the pylorus in infants].","authors":"A Koczyński,&nbsp;H Haselbach","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The assessment of pylorus in the diagnostic procedure of causes of vomiting in infants is very important. The differentiation between organic and functional changes is principal. The survey covers 65 infants aged from 2 weeks to 12 months. In this group there are 14 vomiting neonates, in 6 of them the hypertrophic pyloric stenosis by ultrasound examination was diagnosed and by operation confirmed. Ultrasongraphy in presented children was performed on TOMOSONIC EUB--22 Hitachi (real time) provided with a 3 MHz transducer. The pylorus in children is localized near to the middline in the right epigastrium. In normal pylorus the walls of the canal widen the lumen opens. The diameter of normal pylorus amounts 10 to 15 mm, the thickness of muscular wall about 2 mm. In infants with the hypertrophic pyloric stenosis the three components: the muscle, the wall and the lumen of the canal are exceptionally visualized. The hypertrophied muscle forms a regular cylindrical sleeve around the canal and sometimes the pyloric lumen disappears. The diameter of the pyloric mass amounts about 15 to 30 mm and the thickness of the pyloric wall about 5 to 9 mm. The ultrasound examination let to assess the normal pylorus as well as with great probability to diagnose the hypertrophic pyloric stenosis eliminating also in many cases the conventional x-ray examinations.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"13 ","pages":"78-83"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17456486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Histoenzymatic study of postnatal development of the rat ovary, follicular atresia and interstitial gland].","authors":"E Kaczkowska,&nbsp;M Liebhart","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In our experiment, we investigated histoenzymatic activity od postnatal development of rat ovary, specially the main metabolic process--steroidogenesis. We noticed, that during early folliculogenesis great amount of follicles are eliminated by atresia. Atresia also plays very important role in forming of interstitial gland. Interstitial gland which is found in ovary of 14 days old rat ovaries, morphologically and enzymatically differs from the structure observed on older animals. We concluded, that ovary of 14 days old rat is not developed but ovary of 21 days old rat seems to be morphologically and histochemically well developed.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"13 ","pages":"219-31"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17588372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[45Ca2+ uptake by rat thymocytes in the presence of blood serum of patients with cystic fibrosis].","authors":"T Mańkowski,&nbsp;E Helwich,&nbsp;A Piekarczyk,&nbsp;A Swirska,&nbsp;K Wierzba","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The results of examination of 45Ca2+ (uptake by freshly prepared) thymocytes from rat in the presence of blood serum from CF patients and healthy persons as differentiating agent are presented. The presence of the factor responsible for enhanced Ca uptake in the blood serum of CF patients was found in our experimental system. That factor was absent in the blood serum of rats chronically treated with reserpine. This is in agreement with previous findings that this factor was related to the basic genetic defect in CF(6). Very efficient influx of 45Ca2+ into the rat thymocytes (up to 6,2%) being accompanied by increased calcium uptake in the presence of serum factor of CF patients in comparison with control serum of healthy persons should be underlined.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"13 ","pages":"213-8"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17588371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Pharmacokinetics of 6-mercaptopurine in rats during postnatal development].","authors":"K Wierzba,&nbsp;B Wańkowicz,&nbsp;A Piekarczyk,&nbsp;J Prokopczyk","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It was shown that 6-MP pharmacokinetics in rats was age-dependent. The distribution processes were mainly influenced by age of animals. 6-MP total distribution volume (VD) increased from 26.4 ml in 2 week old animals to 60.2 ml and 55.5 ml in 4-week-old and adult rats, respectively. However, the relative volume of distribution (delta, per cent of body weight) decreased from 1019 ml/kg in 2 week old rats to 317 ml/kg in adult rats. Similar relationships between total body clearance and the age of animals were observed. One may suspect that the changes in the distribution processes are connected both with the increased extracellular water content and the changed protein binding in young animals.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"13 ","pages":"207-12"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17599671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Interferon].","authors":"E Smogorzewska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Twenty five years ago Isaas and Lindenmann discovered that virus-infected cells may release a protein capable of reacting with normal cells and render them resistant to infection by a variety of viruses. That protein, a major mediator of viral interference was called interferon. Three main types of interferon have been identified and originally designated as fibroblast, leukocyte and immune interferon. According to the newly adopted nomenclature (as defined by the International Committee on Interfern Nomenclature) these interferons are now called beta, alpha and gamma interferon, respectively. The use of interferon as a therapeutic agent for tumor-bearing patients has gained considerable interest after reports demonstrated potent enhancing effects of interferon on the immunologic system. Thus, besides its direct effect on tumor cell multiplication, interferon may influence the host-tumor relationship by activating cells with potential antitumor activity such as natural-killer (NK) cells, killer (K) cells or macrophages. Interferon can also modify the metabolism of molecules involved in immunologic functions, such as antigen receptors, histocompatibility antigens or receptors for Fc fragment of immunologlobulins. Systematic clinical trials with interferon have been greatly expanded over the last three or four years. At this time the data support a cautious optimism for the therapeutic value of interferon in both viral and neoplastic diseases.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"13 ","pages":"176-84"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17151990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Electrophysiological studies on the adaptation of eutrophic mature newborn infants during sleep in the first week of life].","authors":"M Pakszys","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of the study was: elaboration of behaviour characteristics of eutrophic healthy newborns during adaptation (first 5 days) by determination of sleep states and interrelation of particular sleep states as well as characteristics of respiratory function in active and quiet sleep. Material comprised 50 eutrophic healthy newborns born at term between 38-41 weeks of conceptional age with body weight 2800-4300 g. 33 newborns were born by spontaneous delivery (SpD) and 17 by primary cesarean section (CS). Normal state of all clinically investigated newborns immediately after delivery and in the newborns period was noted. According to the aim of study polygraphic sleep records were performed in all newborns and they included EEG, chin electromyogram, respiratory and cardiac rates, eye movements and body movements. Recordings time was 2-3 hours. All records were taken during day sleep between 2 feedings (at 9 and 12). From all polygraphic investigations 75 records were selected for detailed analysis. Among them there was 50 records of newborns delivered by SpD and 25 records of newborns delivered by CS. In each consecutive 5 days of life there were analysed 10 records of SpD and 5 of CS. These records were the subject of investigation of behavioural patterns of newborn including sleep and respiratory function in sleep in the first 5 consecutive days of life. Each sleep state (active, quiet and indeterminate) was classified using 4 electropolygraphic parameters (EEG, respiration, eye and body movements). Characteristics of behavioural newborn pattern were determined in consecutive 5 days of life considering the kind of delivery and using quantitative and qualitative analysis of obtained data. Qualitative analysis concerned the occurrence of particular sleep states and the type of the first sleep state beginning the sleep. Quantitative analysis comprised: time duration of wakefulness, time duration of each sleep state--expressed by total time duration of each sleep state and by longest time duration of each sleep state, calculated during 100 minutes of sleep. These values were determined by quantitative analysis of individual records as well as by medium values received from all records in every day of life. Characteristics of respiratory function were analysed analogically in the same 5 days of life with regard to the kind of delivery, independently of active and quiet sleep state.(ABSTRACT TRUNCATED AT 400 WORDS)</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"13 ","pages":"7-28"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17588264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Metabolic balance of zinc in infants and children].","authors":"J Skorkowska-Zieleniewska,&nbsp;W Szotowa,&nbsp;Z Rudzka-Kańtoch,&nbsp;Z Wachnik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Zinc metabolism in infants and children was evaluated on the basis of chemical balance studies of this element. The zinc intake chemically measured oscillated in the broad limits from 0,2 to 17,1 mg/d according to the age and to the manner of feeding; the highly positive zinc retentions were obtained only in infants with high intake of this element. Zinc in the diet of infants in some part derived from water. Low positive retentions were observed by intake in the limits of daily allowances (3-5 mg/d) and by the low content of calcium in the diet. About one half of zinc balances was negative because of relatively low zinc intake and the high calcium intake. The negative zinc balances could be caused also by the suggested presence of antinutritive substances in the diet. The low zinc intake founded in older children (3-10 years) and the low retention of this element could be the reason zinc deficiency states in children of different age.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"13 ","pages":"103-9"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17588520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Preliminary elaboration of the method of specimen collection using fine-needle biopsy in the diagnosis of rhabdomyosarcoma in children].","authors":"J Bozek,&nbsp;W Czerwiński,&nbsp;W Woźniak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fine needle punction proposed by Martin and Ellis in 1931, is a safe method of diagnosis by means of cytology making possible tumoral verification. In group of 24 children with RMS treated in Clinical Department of Child Oncology, Institute of Mother and Child Warsaw during last 2 years, fine needle punction was made in 7 cases. Precise diagnosis was possible after cytological examination in 2 cases. Non-precise diagnosis confirming malignant tumor only, was done in 3 cases. In resting 2 cases there were no material for evaluation, by means of cytology. Anyhow there was tissue material for histopathological examination. No complications in our material was observed. Fine needle punction is a safe method but requires personal experience of the surgeon and pathologist who performed cytological examination. Method seems to useful in advanced tumors when surgery is limited. Precise diagnosis is possible in short time, and early treatment can be done.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"13 ","pages":"150-3"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17588366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Ceruloplasmin, haptoglobin and transferrin levels in bronchial secretions of children with chronic respiratory tract diseases].","authors":"J Gaweł,&nbsp;T Herman,&nbsp;J Zebrak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bronchial secretions from 191 children with various respiratory diseases and from 7 healthy controls were tested for concentration of ceruloplasmin, haptoglobin and transferrin. Highest protein levels were observed in children with bronchiectasis and cystic fibrosis. The protein levels were correlated with the intensity of the inflammatory process.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"13 ","pages":"84-90"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17588266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Preliminary elaboration of the method of complex treatment of rhabdomyosarcoma].","authors":"J Bozek,&nbsp;W Czerwiński,&nbsp;W Woźniak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>24 children with rhabdomyosarcoma were treated in Clinical Department of Pediatric Oncology of the Institute of Mother and Child, Warsaw during last 2 years. Complex therapy consisted of surgery, chemotherapy, radiotherapy and rehabilitation. Choice method of the treatment depends of stagging by Intergroup RMS Study. Basic method is surgery (radical excision with margin of neighbouring tissue). Modern multi-drug chemotherapy has changed strategy of the treatment by means of less extended surgery. Radiotherapy in RMS has to be mega-voltage what gives short time of irradiation and less complication. Rehabilitation as a component of complex therapy of RMS has to preserve function of treated organ and in cases after mutilated surgery becomes rehabilitated procedure.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"13 ","pages":"154-63"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17606819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}