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[Transfer of delayed type hypersensitivity in guinea pigs]. 豚鼠延迟型超敏反应的转移。
Problemy medycyny wieku rozwojowego Pub Date : 1990-01-01
E Smogorzewska
{"title":"[Transfer of delayed type hypersensitivity in guinea pigs].","authors":"E Smogorzewska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the first description of transfer factor in 1955, Lawrence defined it as \"the active principle in viable leukocytes, leukocyte extracts and leukocyte dialysates obtained from immune human donors which has the capacity to transfer cutaneous delayed-type hypersensitivity (DTH) in vivo to nonimmune recipients\". The dialysates are reported to contain a number of antigen-independent activities affecting monocytes, macrophages and lymphocytes. In some cases these \"nonspecific\" activities separate out with the fraction causing skin test conversion, but it has not been shown that the same molecule is responsible for both effects. Chemical structure of transfer factor (TF) has not been defined, yet. Its m.w. is 2000-3500. TF has been used to treat a wide range of clinical disorders, including immunodeficiency diseases, neoplasms, chronic fungal, viral and bacterial infections with varying degrees of reported success. The reports on the efficacy of TF in the prevention of varicella in childhood leukemia evoked renewed interest in possible clinical applications of this leukocyte derived material. There is no convenient animal in vivo model of TF activity investigations, and there is no sensitive and reproducible in vitro assay in regard to its activity and specificity. In presented paper the passive transfer of DTH to tuberculin in guinea pigs was reported, both by intact lymphocytes as well as by its crude homogenate. Sephadex column fractionation of crude leukocyte extract have been done. Attempts to define the in vitro activity of leukocyte extract as well as its fractions by leukocyte migration inhibition test have been made.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"16 ","pages":"167-88"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13306639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Clinical-bioelectric correlation of spastic seizures in children--prospective study]. 儿童痉挛发作的临床-生物电相关性——前瞻性研究。
Problemy medycyny wieku rozwojowego Pub Date : 1990-01-01
A Koślacz-Folga, M Pakszys, W Zdanowska
{"title":"[Clinical-bioelectric correlation of spastic seizures in children--prospective study].","authors":"A Koślacz-Folga,&nbsp;M Pakszys,&nbsp;W Zdanowska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serial electroencephalographic (EEG) records were registered in 63 children (38 boys and 25 girls) at the age between 1 month to 7 years in 1981-1987. Examinations were done while awake and during spontaneous sleep. Evaluation was performed in relation to the age and physiological status during examination. Three hundred ninety two EEGs recorded. The following types were found in the initial EEG records in 63 children: 1-normal, 29-hypo-arrythmic, 16 with generalized paroxysmal abnormalities, 12 with localized abnormalities, and 4 with generalized abnormalities. Table 1--illustrates types of the disorders in initial EEG records. Table 2--evolution of the disorders. Table 3--evolution of the disorders in EEG records in relation to the clinical data. Evaluated data concerning types of EEG records, their evolution during observation, as well as their correlation with some clinical data showed: the most significant relation between types of the initial EEG records and clinical data--occurrence of other types of seizures before infantile spasms, abnormal neurological status and delayed psychomotor development--in relation to hypo-arrythmic records was found. The most significant tendency towards normalization of the initial EEG records was found in relation to generalized paroxysmal abnormalities whereas the least significant tendency was found in relation to initial EEG records with localized abnormalities, and less significant with hypo-arrythmic, normalization of EEG records is most significantly related to: disappearance of infantile spasms and occurrence of this type of seizures as the only spasms, less frequent neurological abnormalities and also delayed psychomotor development.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"16 ","pages":"93-102"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13305868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Appearance of mast cells in the placenta of pregnancies delivered at and before term]. [足月或足月前分娩的孕妇胎盘中肥大细胞的外观]。
Problemy medycyny wieku rozwojowego Pub Date : 1990-01-01
S Soszka, W Kazanowska, K Leoniak
{"title":"[Appearance of mast cells in the placenta of pregnancies delivered at and before term].","authors":"S Soszka,&nbsp;W Kazanowska,&nbsp;K Leoniak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Histologic material included 90 placentas of normal pregnancy and 36 of preterm deliveries. The particular attention was paid to mast cells in connective tissue of placental villi. Samples were fixed in 4% acid formaline and stained both with acridine organ and routine technique. Mast cells were found adjacent chorionic vessels in placentas delivered at term. The same feature was observed in preterm delivered placentas.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"16 ","pages":"125-9"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13307326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Characteristics of "high risk" group in carcinomas of the uterine body]. 【子宫体癌“高危”人群的特点】。
Problemy medycyny wieku rozwojowego Pub Date : 1990-01-01
W Kazanowska, M J Karpowicz, P Knapp
{"title":"[Characteristics of \"high risk\" group in carcinomas of the uterine body].","authors":"W Kazanowska,&nbsp;M J Karpowicz,&nbsp;P Knapp","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Forty nine patients with carcinoma of the uterine body were examined. Four hundred ninety one normal females served as controls. The risk factors included: age over 30, premenstrual tension syndrome and postmenopausal uterine bleeding, advanced age at first pregnancy, infertility, hormonal treatment, mammary gland disorders, irregular prophylactic follow-up.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"16 ","pages":"149-54"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13307330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Infectious complications from intraventricular route of administration in cancer patients]. [癌症患者脑室内给药途径引起的感染并发症]。
Problemy medycyny wieku rozwojowego Pub Date : 1990-01-01
D Perek, J R Commers, D G Poplack, P A Pizzo
{"title":"[Infectious complications from intraventricular route of administration in cancer patients].","authors":"D Perek,&nbsp;J R Commers,&nbsp;D G Poplack,&nbsp;P A Pizzo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Intraventricular drug administration via the IR is often used in the therapy of leukemic and carcinomatous meningitis. We reviewed our 10-year experience with 32 patients, with IR placed for intraventricular chemotherapy to characterize infectious complications associated with IR. Infectious complications occurred in 9 patients (27.1%). Local cellulitis (S. aureus) occurred at the site of IR in 2 patients. Seven patients (21.8%) had 12 episodes of bacteriologically proven or clinically suspected meningitis, or positive IR CSF cultures without symptoms (4-P. acnes). While patients with local infection may require IR removal, more than half of those with meningitis may be treated with antibiotics alone without IR removal. Patients with positive cultures in the absence of symptoms may require no therapy at all.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"16 ","pages":"45-53"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13306646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The concentration of uric acid in twenty-four hour urine collections of health children in various age groups]. [不同年龄组健康儿童24小时尿液尿酸浓度分析]。
Problemy medycyny wieku rozwojowego Pub Date : 1990-01-01
D Banaś, B Gołabek
{"title":"[The concentration of uric acid in twenty-four hour urine collections of health children in various age groups].","authors":"D Banaś,&nbsp;B Gołabek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The concentration of uric acid in a 24-hour urine of 94 healthy children was determined. The concentrations of uric acid and numbers of children of various groups of age are presented in table I and II.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"16 ","pages":"31-5"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13306644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Evaluation of results after treatment of children with Ewing's sarcoma during a presentation of the material at the clinical pediatric oncology department of the Oncology Institute of Mother and Child during 1962--1982]. 【在1962年至1982年期间，在母亲和儿童肿瘤研究所临床儿科肿瘤科的一次报告中，对尤因氏肉瘤儿童治疗后的结果进行评估】。
Problemy medycyny wieku rozwojowego Pub Date : 1990-01-01
W Woźniak
{"title":"[Evaluation of results after treatment of children with Ewing's sarcoma during a presentation of the material at the clinical pediatric oncology department of the Oncology Institute of Mother and Child during 1962--1982].","authors":"W Woźniak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Forty seven cases of Ewing's sarcoma in children are discussed. This group was divided in two subgroups. The first (23 children) included patients treated with radiotherapy and monodrug chemotherapy non systematically--1 patient alive. The second (24 children) included patients treated with multidrug chemotherapy systematically and radiotherapy. Good results of the treatment was obtained in 8 patients from the second group with localised neoplastic disease.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"16 ","pages":"69-74"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13306647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Degradation and consumption of one's own glycogen in placental tissue in pregnancy complicated by gestosis and anemia]. [妊娠期胎盘组织自身糖原的降解和消耗，并发妊娠和贫血]。
Problemy medycyny wieku rozwojowego Pub Date : 1990-01-01
M Jóźwik, A Sledziewski, A Jasiewicz, G Sajewska, A Kozanecki
{"title":"[Degradation and consumption of one's own glycogen in placental tissue in pregnancy complicated by gestosis and anemia].","authors":"M Jóźwik,&nbsp;A Sledziewski,&nbsp;A Jasiewicz,&nbsp;G Sajewska,&nbsp;A Kozanecki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We estimated in vitro degradation and consumption of glycogen by placental tissue derived from pregnancies complicated by gestosis and anemia. Placental tissue was incubated in suitable medium. Glycogen concentration either before or after incubation was assayed. Glycogen consumption was expressed as micromoles of glucose per 1 g of wet tissue, the percentage of glycogen consumption has been shown in tables. It is concluded that in advanced gestosis and severe anemia of pregnancy the consumption of native glycogen is increased, consequently it may lead to metabolic insufficiency of human placenta.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"16 ","pages":"131-5"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13307327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Health status of 11- year old pupils depending on their school maturity determined at the age of 6 years]. [11岁学生的健康状况，取决于他们在6岁时的学业成熟度]。
Problemy medycyny wieku rozwojowego Pub Date : 1990-01-01
B Ignar-Golinowska, H Cerańska-Goszczyńska, M Pułtorak
{"title":"[Health status of 11- year old pupils depending on their school maturity determined at the age of 6 years].","authors":"B Ignar-Golinowska,&nbsp;H Cerańska-Goszczyńska,&nbsp;M Pułtorak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The results of follow-up studies in 323 children, examined by extended health balance method in 1977 and 1981 are prescuted. In repeated examination of 11-year old pupils health status changes during the first years of school were analysed, depending on their school maturity groups in the I examination at the age of 6 years. Increasing number of disorders in children's health status both in the group with full and partial school maturity was observed. The incidence of these disorders, was however significant in the group with partial school maturity.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"16 ","pages":"155-61"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13307331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Morphologic examination of ovaries and liver after repeated administration of cyclophosphamide in therapeutic low doses to immature experimental rodents in various stages of individual maturity]. [个体成熟不同阶段的未成熟实验啮齿动物反复给予低剂量环磷酰胺治疗后卵巢和肝脏的形态学检查]。
Problemy medycyny wieku rozwojowego Pub Date : 1990-01-01
M Liebhart, I Koch, E Kaczkowska
{"title":"[Morphologic examination of ovaries and liver after repeated administration of cyclophosphamide in therapeutic low doses to immature experimental rodents in various stages of individual maturity].","authors":"M Liebhart,&nbsp;I Koch,&nbsp;E Kaczkowska","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Liver and ovarian tissue samples of the immature healthy Wistar rats were examined histologically after administration of the repeated low doses of cyclophosphamide. The youngest experimental group was at the age of 7/14 days. Morphologic examination involved histochemical, histoenzymatic, morphometric and ultrastructural techniques. The observed changes in the liver tissue were minimal and totally reversible at time of animals maturity. Pathomorphological changes in ovaries were more evident and complex, concerning all structures of the gland. The dominant features of the damage included the disturbances of the physiological morphological maturation and the widespread hyperluteinization of all structures. In spite of the morphological changes, the activity of the hydroxysteroid dehydrogenases in ovaries remained unchanged.</p>","PeriodicalId":76348,"journal":{"name":"Problemy medycyny wieku rozwojowego","volume":"16 ","pages":"197-203"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13306640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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