Perspectives in nephrology and hypertension最新文献_第2页

Urine amine excretion in pregnancy-induced hypertension. 妊娠高血压尿胺排泄的研究。

Perspectives in nephrology and hypertension Pub Date : 1976-01-01

F P Zuspan, C Kawada

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The differential diagnosis between preeclamptic toxemia and glomerulonephritis in patients with proteinuria during pregnancy. 妊娠期蛋白尿患者子痫前期毒血症与肾小球肾炎的鉴别诊断。

Perspectives in nephrology and hypertension Pub Date : 1976-01-01

P Kincaid-Smith, K F Fairley

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The effect of estrogens on renal sodium excretion in the dog. 雌激素对犬肾钠排泄的影响。

Perspectives in nephrology and hypertension Pub Date : 1976-01-01

J A Johnson, J O Davis

{"title":"The effect of estrogens on renal sodium excretion in the dog.","authors":"J A Johnson, J O Davis","doi":"","DOIUrl":"","url":null,"abstract":"The effects of estrogens on electrolyte balances were studied in dogs. In doses of 1 mg or 250 mug/day, 17 beta-estradiol produced moderate sodium retention, whereas 100 mug/day produced only slight sodium retention. Estriol produced about the same degree of sodium retention as did estradiol. The administration of estradiol during the injection of large doses of DOCA produced the same degree of sodium retention as estradiol administered alone. Also, the injection of DOCA to estrogen-treated dogs resulted in a transitory sodium retention, followed by a sodium escape and a return to the previous balance level. Estradiol given to dogs with an arteriovenous shunt that had failed previously to show sodium escape during treatment with DOCA produced the same degree of sodium retention as that observed during estradiol administration to normal dogs. Five adrenalectomized dogs maintained on cortisone and DOCA had normal sodium balances during the control period but showed a retention of sodium during the administration of estradiol; administration. Four adrenalectomized dogs maintained only on cortisone were in negative sodium balance during the control period, but during estradiol treatment they showed a retention of sodium. These studies provide evidence that estrogens promote sodium retention in dogs by mechanisms other than by decreasing the glomerular filtration rate, increasing the secretion rates of adrenal steroids, or affecting the sodium escape mechanism. It is suggested that estrogens might act directly on the renal tubules at receptors other than those for the adrenal mineralocorticoids to produce sodium retention.","PeriodicalId":76319,"journal":{"name":"Perspectives in nephrology and hypertension","volume":"5 ","pages":"239-48"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12188295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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The renin-angiotensin system in mother and fetus at cesarean section: a preliminary communication. 剖宫产术中母体与胎儿肾素-血管紧张素系统的初步交流。

Perspectives in nephrology and hypertension Pub Date : 1976-01-01

S Oparil, J Low, E N Ehrlich, M D Lindheimer

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Morphological and immunological evidence of coagulopathy in renal complications of pregnancy. 妊娠肾并发症凝血功能障碍的形态学和免疫学证据。

Perspectives in nephrology and hypertension Pub Date : 1976-01-01

A E Seymour, O M Petrucco, A R Clarkson, W D Haynes, J R Lawrence, B Jackson, A J Thompson, N M Thomson

{"title":"Morphological and immunological evidence of coagulopathy in renal complications of pregnancy.","authors":"A E Seymour, O M Petrucco, A R Clarkson, W D Haynes, J R Lawrence, B Jackson, A J Thompson, N M Thomson","doi":"","DOIUrl":"","url":null,"abstract":"Renal biopsies in 14 patients with P.E.T. or eclampsia showed constant I.F. reactions for IgM and fibrin, with frequent reactions for C1q and C3. The glomeruli showed reversible mesangial proliferation and swelling, with characterictic E.M. deposits, and segmental lesions were present in seven patients. Similar I.F. reactions occurred in three other patients with clinical diagnoses of P.E.T. whose biopsies demonstrated coexistent glomerular disease. Serum complement studies showed a significant rise in C3 in the third trimester of normal pregnancies and a further significant elevation in C1q and C3 in the third trimester of a series of unselected P.E.T. patients. In contrast, four patients from the biopsy series with eclampsia or severe P.E.T. showed profound depression of serum C3 and C4, at the time of maximum clinical severity, which was shown to return to normal in two patients. The I.F. findings confirm those of Petrucco et al (6), and, with the other data, suggest that immune-complex deposition and activation of the classical complement pathway could interrect with intravascular coagulation to produce the glomerular lesions of P.E.T. and eclampsia.","PeriodicalId":76319,"journal":{"name":"Perspectives in nephrology and hypertension","volume":"5 ","pages":"139-53"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11285880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Renal involvement in systemic diseases in childhood. 儿童全身性疾病的肾脏受累。

Perspectives in nephrology and hypertension Pub Date : 1976-01-01

L B Travis, L Street, E Smith, B Chipps

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Uric acid and the kidney. 尿酸和肾脏。

Perspectives in nephrology and hypertension Pub Date : 1976-01-01

E J Weinman

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Lupus nephritis: natural history and therapy. 狼疮性肾炎:自然史与治疗。

Perspectives in nephrology and hypertension Pub Date : 1976-01-01

B Hecht, N J Siegel, M Kashgarian, J P Hayslett

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Urinary kallikrein in normal and hypertensive pregnancies. 尿钾激肽在正常妊娠和高血压妊娠中的作用。

Perspectives in nephrology and hypertension Pub Date : 1976-01-01

O A Elebute, I H Mills

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Proteinuria and the renal lesion in preeclampsia and abruptio placentae. 蛋白尿与子痫前期和胎盘早剥的肾脏损害。

Perspectives in nephrology and hypertension Pub Date : 1976-01-01

J S Robson

{"title":"Proteinuria and the renal lesion in preeclampsia and abruptio placentae.","authors":"J S Robson","doi":"","DOIUrl":"","url":null,"abstract":"The defect in glomerular permeability that leads to proteinuria can be assessed by determining the relative clearance of macromolecules of known but different dimensions, that is, glomerular selectivity. Such estimates can be made using naturally occurring plasma proteins and dextran or polyvinylpyrrolidone injected into the circulation. In preeclampsia, protein and dextran selectivities show good concordance. The proteinuria is intermediate in its selectivity. These findings confirm that proteinuria is glomerular in origin and that the glomerular abnormality is uniform throughout the majority of functioning glomeruli. In abruptio, protein selectivity is very low and dextran selectivity is high. This pattern is seen also in acute ischemic renal failure and suggests that the true glomerular functional defect is actually less severe than in preeclampsia and that much of the protein in the urine in abruptio is postglomerular in origin. The structural lesion in preeclampsia is \"characteristic\" only in the sense that a number of individual components of glomerular injury, which are themselves commonly seen in other glomerular disorders, occur in a particular balance, and not because of any single unique or specific feature. The important components--that is, endothelial swelling, mesangial cytoplasmic activity, subendothelial deposits, and occational thrombosis of the afferent arterioles--all occur, albeit to a lesser degree, in abruptio placentae, as well as in other glomerular disorders in which intravascular coagulation is a primary cause or plays a major role.","PeriodicalId":76319,"journal":{"name":"Perspectives in nephrology and hypertension","volume":"5 ","pages":"61-73"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12186667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0