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Padiatrie und Padologie. Supplementum最新文献

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[Plasma androgens and maturation of the hypothalamo-pituitary-gonadal axis in infants and children (author's transl)]. [血浆雄激素与婴儿和儿童下丘脑-垂体-性腺轴的成熟[作者译]。
Padiatrie und Padologie. Supplementum Pub Date : 1977-01-01
M G Forest
{"title":"[Plasma androgens and maturation of the hypothalamo-pituitary-gonadal axis in infants and children (author's transl)].","authors":"M G Forest","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The plasma androgens testosterone (T) and delta(4)-androstenedione (delta(4)) were measured by RIA in 245 children under 1 year of age, in 70 children of prepubertal age, and in 250 adolescents during puberty. The values presented in the tables, and their changing relation to each other, suggest, that 1. at birth T and delta(4) are of fetal origin demonstrating the important endocrine function of the fetal testis; 2. after 6 months of age there is no significant endocrine activity of the gonads any more; 3. the prepubertal activation of the adrenal androgens production (adrenarche) is similar in the 2 sexes but their chronology is different for each androgen: an increase is observed after age 8 for delta(4), after age 10 for T. 4. in puberty the increase of T- and delta(4)-values differs markedly according to the two sexes. So, while the gradual prepubertal maturation of androgen steroid production, passing the stage of \"adrenal puberty\", could be demonstrated convincingly, the role of the different androgens in the maturation of the \"gonadostat\" (hypothalamopituitary complex) still remains a matter of hypothesis.</p>","PeriodicalId":76299,"journal":{"name":"Padiatrie und Padologie. Supplementum","volume":" 5","pages":"13-28"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12099598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A new method for the determination of steroidal hormones in biological material (adrenal tissue) (author's transl)]. [一种测定生物材料(肾上腺组织)中甾体激素的新方法[作者译]。
Padiatrie und Padologie. Supplementum Pub Date : 1977-01-01
K Herkner, J Jörg, W Waldhäusl, H Haschek
{"title":"[A new method for the determination of steroidal hormones in biological material (adrenal tissue) (author's transl)].","authors":"K Herkner,&nbsp;J Jörg,&nbsp;W Waldhäusl,&nbsp;H Haschek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A rapid method is described for the determination of some steroidal hormones in adrenal tissue. The following steroids were measured: pregnenolone, progesterone, deoxycorticosterone, corticosterone, aldosterone, 17-alpha-OH-pregnenolone, deoxycortisol, cortisol, cortisone, 17-alpha-OH-progesterone, dehydroepiandrosterone, androstendione, and testosterone. After extraction of the steroids the purification steps were performed by thin layer chromatography. Gas chromatography was used for further separation and quantitative analysis of underivatized steroids. The GC-analysis of steroids without any derivatisation makes this procedure comparatively simple and exact. Recovery of the steroid content of the tissue ranged from 30% to 70%. This method described herewith has several advantages, and allows the analysis of two tissues at the same time for a large number of adrenal steroids within two weeks.</p>","PeriodicalId":76299,"journal":{"name":"Padiatrie und Padologie. Supplementum","volume":" 5","pages":"57-61"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12099602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Possibilities of treatment of maldescensus testis in the dog (author's transl)]. [犬睾丸下伸症治疗的可能性(作者译)]。
Padiatrie und Padologie. Supplementum Pub Date : 1977-01-01
G Schörner, H S Choi
{"title":"[Possibilities of treatment of maldescensus testis in the dog (author's transl)].","authors":"G Schörner,&nbsp;H S Choi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The diagnosis of inguinal retention of the testis can be made in the dog from the 10th week of life. Like in man, therapy of this condition can be done with gonadotropins or releasing hormones. In conditions with retention of the testicles in the upper inguinal region LH-RH proved to be more successful than gonadotropin. 10 out of 16 patients showed a complete descent of the testes. In addition the effect of plasmagonadotropin as well as urinary chorionic gonadotropin, and of LH-RH on the plasma testosterone levels of juvenile and adult dogs was studied. It could be seen that in the young dogs all 3 hormones caused an increase in plasma testosterone, while in the adult animal only LH-RH was able to produce a significant rise.</p>","PeriodicalId":76299,"journal":{"name":"Padiatrie und Padologie. Supplementum","volume":" 5","pages":"43-8"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11244415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Possibility of a TSH-Screening method for detection of hypothyroidism in the newborn (author's transl)]. [tsh筛查方法检测新生儿甲状腺功能减退的可能性[作者简介]。
Padiatrie und Padologie. Supplementum Pub Date : 1977-01-01
R Illig, C R de Vera Roda
{"title":"[Possibility of a TSH-Screening method for detection of hypothyroidism in the newborn (author's transl)].","authors":"R Illig,&nbsp;C R de Vera Roda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In congenital hypothyroidism the TSH level reaches at age 5 days values about 100-times of the normal. Due to this fact, and having a good RIA-method for TSH in the own lab at hand, the possibility of TSH-determination in dried wholeblood on a filter-paper was examined. Control studies with normal blood-samples proved that the values of dried-blood samples had sufficient accuracy. On the 5th day of life the normal TSH-values were below 20 muU/ml while values above 100 muU/ml were suspicious for hypothyroidism. In 1200 newborns the TSH-screening was performed in combination with the routine Guthrie-test. Among them one child with a value above 100 muU/ml proved to have hypothyroidism. The results show that the determination of TSH in dried blood is possible, and that the method described is a useful tool for the early diagnosis of primary hypothyroidism.</p>","PeriodicalId":76299,"journal":{"name":"Padiatrie und Padologie. Supplementum","volume":" 5","pages":"129-34"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12099597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Plasma prolactin in different age groups (author's transl)]. [不同年龄组血浆催乳素(作者译)]。
Padiatrie und Padologie. Supplementum Pub Date : 1977-01-01
W H Weiske, J Frick
{"title":"[Plasma prolactin in different age groups (author's transl)].","authors":"W H Weiske,&nbsp;J Frick","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After a detailed introduction to the problems of radioimmunological measurement of Prolactin and a review of the possible connections between PRL and urological and andrological diseases, respectively, the results of Prolactin measurements carried out with a Prolactin Radioimmunoassay Kit (Cea-Ire-Sorin) will be described. This Kit makes use of the \"double antibody\" method. In 99 healthy male subjects the plasma levels of Prolactin in 3 age groups were ascertained. These were as follows: Group I ages 10 to 20: 2.4+/-1.2 ng/ml; group II ages 20 to 40: 3.9+/-1.5 ng/ml; group III ages 50 to 80: 5.2+/-3.8 ng/ml. In the cases of 4 patients suffering from prostate cancer stage D, treated with hormones at various intervals and after orchiectomy the range of PRL levels was 13.1--18.7 ng/ml.</p>","PeriodicalId":76299,"journal":{"name":"Padiatrie und Padologie. Supplementum","volume":" 5","pages":"49-55"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12099601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Screening for hypothyroidism in the newborn with a total T 4-RIA method (author's transl)]. [全t4 - ria法筛查新生儿甲状腺功能减退[作者简介]。
Padiatrie und Padologie. Supplementum Pub Date : 1977-01-01
H Fritzsche, M Weissel, R Höfer, H Frisch, O Thalhammer, H Kolbe
{"title":"[Screening for hypothyroidism in the newborn with a total T 4-RIA method (author's transl)].","authors":"H Fritzsche,&nbsp;M Weissel,&nbsp;R Höfer,&nbsp;H Frisch,&nbsp;O Thalhammer,&nbsp;H Kolbe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A screening method for detection of congenital hypothyroidism is presented in detail in cooperation with the \"Austrian Program for Inborn Errors of Metabolism\". Screening is performed by measuring the total T4-content of 1/8 inch filter paper dots filled with dried blood of newborns. The strategy for recall of newborns with borderline or pathological T4-values used, results in a definite diagnosis on day 55 of life. The advantages of additional TSH determination in the filter paper dots are discussed. So far (Sept. 1976) 8645 newborns have been investigated, covering the regions of Vienna and Carinthia (Austria). Preliminary studies reveal a slight dependency of the measured T4-values on the day of sampling. Two congenitally hypothyroid children have been diagnosed so far, corresponding fairly well with the reported frequency in the literature (1 : 6000).</p>","PeriodicalId":76299,"journal":{"name":"Padiatrie und Padologie. Supplementum","volume":" 5","pages":"135-43"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12099599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Investigations of the urinary cAMP-excretion in pseudohypoparathyroidism (author's transl)]. 假性甲状旁腺功能低下患者尿camp排泄的研究[作者译]。
Padiatrie und Padologie. Supplementum Pub Date : 1977-01-01
W Stögmann
{"title":"[Investigations of the urinary cAMP-excretion in pseudohypoparathyroidism (author's transl)].","authors":"W Stögmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pseudohypoparathyroidism (PHP) is a hereditary disorder with typical dysmorphic signs and clinical and laboratory symptoms of hypoparathyroidism which is resistant however to parathyroid extract. ALBRIGHT and coworkers supposed that this resistance was caused by an inability of the renal tubules to respond to parathyroid hormone. On three children, suffering from PHP, we could demonstrate that parathyroid extract-resistance disappears during treatment with vitamin D. Measurements of urinary excretion of cAMP, the second messenger for parathyroid hormone, in the same patients showed low basal levels of this nucleotide, which could not be stimulated by parathyroid extract either before or during vitamin D-treatment. This constantly low and by parathyroid extract not stimulable cAMP-excretion is now the symptom with the most diagnostic value for PHP. Beyond this the finding of this defective urinary excretion of cAMP in PHP was able to explain the hitherto unknown pathogenesis of this disorder: the parathyroid hormone -- sensitive adenylcyclase system is here unable to mediate the action of parathyroid hormone on its target cells, so causing a peripheral block of parathyroid-hormone activity. Therefore GREENBERG and coworkers justly term PHP a disease of the second messenger.</p>","PeriodicalId":76299,"journal":{"name":"Padiatrie und Padologie. Supplementum","volume":" 5","pages":"63-9"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11415822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Dietetic adaptation with semi-digested food--parenteral nutrition, chemically defined diet, formula diet]. [饮食适应与半消化食物-肠外营养，化学定义饮食，配方饮食]。
Padiatrie und Padologie. Supplementum Pub Date : 1975-01-01
K Schultis
{"title":"[Dietetic adaptation with semi-digested food--parenteral nutrition, chemically defined diet, formula diet].","authors":"K Schultis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The fundamentals of parenteral nutrition and the possibilities of oral nutrition with chemically defined diets are described. The possibilities are discussed against the background of a review of nutritional pathophysiology and the use of the available preparations set out.</p>","PeriodicalId":76299,"journal":{"name":"Padiatrie und Padologie. Supplementum","volume":"3 ","pages":"70-84"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11995915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Clinical aspects of chromosomal aberrations - problems of semiotics and nosography]. 【染色体畸变的临床方面——符号学和分类学问题】。
Padiatrie und Padologie. Supplementum Pub Date : 1975-01-01
B Leiber
{"title":"[Clinical aspects of chromosomal aberrations - problems of semiotics and nosography].","authors":"B Leiber","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Despite intense clinical and cytogenetic research for more than 15 years we are far from knowing any definite relations between karyotype and phenotype. Both cytogeneticists and clinicians are working on the methodological improvements which are still necessary. In the methods of clinical recording there is still very great weakness of exact documentation of findings. Above all there is a lack of reproducible qualitative, and especially quantitative standards which constitute the basis of any practicable nosography. Some procedures for quantifying dysplastic facial features which have hardly been described so far (graphic statistics) are reported briefly. Also the summation of symptoms, a method currently used in the field of chromosomopathy syndromes, is subject to critical consideration. In this group of diseases a total list of symptoms of about 250 items can be obtained which includes multilocular minor stigmata, dysplasias, errors of differentiation and gross malformations of organs. An extraordinarily high degree of overlapping of symptoms is characteristic of these syndromes and makes accurate diagnosis difficult. However, for the trisomy-syndromes we succeeded in working out a diagnostic guideline by differentiating between an unspecified basic symptomatology concerning all trisomias and a pattern-forming additional symptomatology of each single syndrome. Thereby the diverse total symptomatology is reduced to the crucial and the recognition of patterns in daily practice is facilitated considerably. The comparatively specific additional symptomatologies of trisomy 13 -- 14 (Patau), trisomy 17 -- 18 (EDWARDS), and trisomy 21 (DOWN) are demonstrated in graphic views.</p>","PeriodicalId":76299,"journal":{"name":"Padiatrie und Padologie. Supplementum","volume":"4 ","pages":"32-47"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11346649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[On the mental structure of mongolism (author's transl)]. [论蒙古族心理结构(作者译)]。
Padiatrie und Padologie. Supplementum Pub Date : 1975-01-01
M Heumayer-Skritek
{"title":"[On the mental structure of mongolism (author's transl)].","authors":"M Heumayer-Skritek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Forty-nine mongol and 48 non-mongol test persons of equivalent age and intelligence were selected and investigated with respect to intelligence components (S-I-T), motoricity (LOS), fine motoricity (KP), memorizing capacity (BA), working tempo (BS) and organization of the perceptual field (MZT). There were significant differences in S-I-T in favor of non-mongols in verbal tasks and in the LOS in favor of the mongoloids in rhythmic tasks. There was a tendency for the mongoloids to have poorer results for working tempo and fine motoricity. The differences in capacity to memorize and organization of perception were not significant.</p>","PeriodicalId":76299,"journal":{"name":"Padiatrie und Padologie. Supplementum","volume":"4 ","pages":"70-82"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11346652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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