Salah Saber Mabrouk, Essam El-Din Abd El-Azim El-Desouky, Abd El-Fattah Morsy Saeid
{"title":"COMPARATIVE STUDY BETWEEN PANCREATICOJEJUNOSTOMY AND PANCREATICOGASTROSTOMY FOLLOWING PANCREATICODUODENECTOMY","authors":"Salah Saber Mabrouk, Essam El-Din Abd El-Azim El-Desouky, Abd El-Fattah Morsy Saeid","doi":"10.21608/amj.2023.326883","DOIUrl":"https://doi.org/10.21608/amj.2023.326883","url":null,"abstract":"Background: Pancreaticojejunostomy and pancreaticogastrostomy are the two techniques for pancreatic anastomosis that are widely established for the reconstruction after pancreaticoduodenectomy. Aim: To study the effect of the type of pancreaticoenteric reconstruction pancreaticojejunostomy versus pancreaticogastrostomy (PJ versus PG) after pancreaticoduodenectomy regarding the post-operative mortality and morbidity particularly pancreatic fistula (PF). Patients and Methods: A prospective cohort study included 40 patients with pancreatic or periampullary cancer who undergone pancreaticoduodenectomy. The patients divided randomizly into two groups; Group (A)included 20 patients who had undergone pancreaticojejunostomy reconstruction while group (B) included 20 patients who had undergone pancreaticogastrostomy reconstruction. Results: Mean operative time in group A and B was 7.6 ± 2.2 and 7.2 ± 2.7, mean blood loss 984.7 ± 253.2 and 852.5 ± 152.6, in most of the cases there was a Drains in contact with anastomosis was 85% and 70%, respectively. Also, there is no significant difference between both groups regarding intraoperative data. Considering postoperative complications, there was significant difference between both groups regarding","PeriodicalId":7627,"journal":{"name":"Al-Azhar Medical Journal","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139325320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed Fawzi Gabena, Mohamed Nabil Rafaat, Hendawy Abd El-Moaty Zidan, Abd El-Raouf Mahmoud Abo Nar
{"title":"ASSESSMENT OF SERUM AUTOTAXIN AS NOVEL BIOMARKER OF LIVER CIRRHOSIS","authors":"Ahmed Fawzi Gabena, Mohamed Nabil Rafaat, Hendawy Abd El-Moaty Zidan, Abd El-Raouf Mahmoud Abo Nar","doi":"10.21608/amj.2023.326111","DOIUrl":"https://doi.org/10.21608/amj.2023.326111","url":null,"abstract":"Background: Autotaxin and its product lysophosphatidic acid are considered to be involved in the development of liver cirrhosis and elevated levels of serum autotaxin have been found in patients with hepatitis C virus associated liver disease. Objective: The clinical role of systemic autotaxin in the stages of liver cirrhosis was unknown. So, in our study we investigated the utility of serum autotaxin level as a marker of liver cirrhosis. Methods: Patients with liver cirrhosis were prospectively enrolled. Blood samples drawn at the day of inclusion in the study were assessed for autotaxin content by an enzyme-linked immunosorbent assay. Autotaxin levels were correlated with liver cirrhosis. The diagnostic value of autotaxin was investigated by analyses. Results: 60 subjects were enrolled. Cirrhotic group had highest level of serum Autotaxin (105.86 ± 14.85 mg/l, p1<0.001) compared to hepatitis C virus non cirrhotic group (81.98 ± 11.31 mg/l, p2<0.001) and to control group (42.52 ± 4.95 mg/l, p3<0.001) with statistically significant difference and also hepatitis c non cirrhotic group had higher level compared to Control group by using of one-way ANOVA test. Conclusion: Our findings supported that serum Autotaxin level is a valuable test for detection of cirrhosis and associated with the severity of liver cirrhosis","PeriodicalId":7627,"journal":{"name":"Al-Azhar Medical Journal","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139330972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mosab El-Khair Abdul-Azeem Ghaitah, Abdul-Nabi Byoumi Mohammed, Mahmoud Ibrahim El-Shamy
{"title":"MRI ASSESSMENT OF CSF FLOW AND DIAGNOSIS OF NORMAL PRESSURE HYDROCEPHALUS","authors":"Mosab El-Khair Abdul-Azeem Ghaitah, Abdul-Nabi Byoumi Mohammed, Mahmoud Ibrahim El-Shamy","doi":"10.21608/amj.2023.326102","DOIUrl":"https://doi.org/10.21608/amj.2023.326102","url":null,"abstract":"Background: Normal-pressure Hydrocephalus is a clinical triad of gait disturbance, subcortical dementia, and urinary incontinence in a patient who has communicating hydrocephalus. Objective: To reveal the role of phase-contrast MR imaging in the detection of normal pressure hydrocephalus among patients with ventriculomegaly. Patient and Methods: The study group included 40 patients with ventriculomegaly. Patients were referred to the multiple MRI centers (including Nile Scan Radiology Center and Watani Scan Radiology Center), Radiology Department of AL Mokatam Hospital. The consensus about final diagnosis in the ventriculomegaly group was reached on the light of the typical clinical findings and typical conventional MRI findings. The study was done between January 2018 and June 2020. The study was performed on 1.5 Tesla imager, using pulse -gated, cine-phase-contrast MRI technique and CSF quantification software. Results: This study revealed that the surest phase contrast MRI parameters in predicting normal pressure hydrocephalus was a CSF aqueductal stroke volume greater than 42 μL having a positive predictive value100%. Conclusion: The study yielded considerable information on the physiology of the normal CSF circulation, and in the evaluation of pathological CSF flow dynamics in normal pressure hydrocephalus that provided a better method of selecting those patients with hydrocephalus who gain benefit most from shunt operation.","PeriodicalId":7627,"journal":{"name":"Al-Azhar Medical Journal","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139329624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed El-Haddad Ali Moussa, Ahmed Abd El-Fattah Abu-Rashed, Mohamed Fathy Fahmy Al-Halawany
{"title":"ULTRASONOGRAPHY AND MR ARTHROGRAM IN DETECTION OF SHOULDER JOINT DISORDERS","authors":"Mohamed El-Haddad Ali Moussa, Ahmed Abd El-Fattah Abu-Rashed, Mohamed Fathy Fahmy Al-Halawany","doi":"10.21608/amj.2023.326105","DOIUrl":"https://doi.org/10.21608/amj.2023.326105","url":null,"abstract":"Background: Ultrasonography and Magnetic Resonance Imaging (MRI) are widely used to detect a lot of the shoulder joint pathologies as rotator cuff, labral, and capsular abnormalities. Objective: to detect role of ultrasonography and MR Arthrogram in detection of shoulder joint disorders in comparison to conventional MRI. Patients and methods: Thirty patients underwent ultrasound examination, conventional MR imaging of the shoulder and MR shoulder arthrography for clinically suspected labral or rotator cuff abnormalities. This study was done at the Radiodiagnosis Department, Al-Azhar University Hospitals during the period between October 2019 and October 2020. Results: MR arthrography was found superior over conventional MRI in its sensitivity regarding specifically labral tears Whereas 0% of patients were found positive by conventional MRI, 10% of patients were detected by magnetic resonance arthrography (MRA), followed by bankert lesion being positive in 7% by conventional MRI, whereas 27% were proved positive by MRA, anterior labrum periosteal sleeve avulsion (ALPSA) was negative in 100% of patients who underwent conventional MRI, 3% positive result was detected by Magnetic Resonance Angiogram (MRA), and finally compared to 3% positive superior labral anterior posterior (SLAP) cases detected by conventional MRI, 7% positive cases were proved by MRA. Conclusion: Ultrasound together with MR arthrography enhanced the accuracy of MR in the evaluation of the glenoid labrum and rotator cuff tendon.","PeriodicalId":7627,"journal":{"name":"Al-Azhar Medical Journal","volume":"293 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139328370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abd El-Aziz Mohammed Abo-Youssef, Ahmed Mostafa Kamal, Wahed Yousre Mohammed Abd El-Aziz
{"title":"THE POSSIBLE PROTECTIVE ROLE OF N-ACETYLCYSTEINE AGAINST TRAMADOL- INDUCED NEPHROTOXICITY IN THE ADULT ALBINO RATS (LIGHT AND ELECTRON MICROSCOPIC STUDY)","authors":"Abd El-Aziz Mohammed Abo-Youssef, Ahmed Mostafa Kamal, Wahed Yousre Mohammed Abd El-Aziz","doi":"10.21608/amj.2023.326108","DOIUrl":"https://doi.org/10.21608/amj.2023.326108","url":null,"abstract":"Background: Tramadol is nephrotoxic in over doses N-acetylcysteine is effective against inflammatory processes and oxidative stress. Objective: Study of tramadol-induced nephrotoxicity on the rats and assess the possible protection of N-acetylcysteine. Material and Methods: Forty adult albino rats were obtained from the breading animal house of Faculty of Pharmacy, Al-Azhar University. The rats were housed in the animal house at Faculty of Pharmacy, Al-Azhar University under the suitable and standard conditions of temperature and feeding from January, 2021 till February, 2021. The rats were divided into four groups Group I (control group): the rats of this group was given 30 ml /kg saline daily for thirty days orally; group II (treated with tramadol): the rats of this group were given l5.5 mg /kg tramadol orally daily for thirty days; Group III (Toxic dose tramadol): The rats of this group were given 30 mg /kg tramadol orally daily for thirty days; Group IV (treated with toxic dose of tramadol and N-acetyl cysteine): The rats of this group were given 30 mg /kg tramadol and N-acetylcysteine 100 mg/kg orally daily for thirty days. The rats at the last day of the experiment were killed and their kidneys were collected for histological evaluation using hematoxylin and eosin and Masson trichrome, and examined under light and transmission electron microscope. Also, Blood samples were taken for measurement of urea and creatinine. The data obtained from biochemical results for all groups were expressed as means and subjected to statistical analysis. Results: Treatment of rats with toxic dose of tramadol (group III) showed marked damage in the renal tissues, The damage in the renal tissues was improved in rats that were given N-acetylcysteine together with tramadol (group IV). However, tramadol that was given in a therapeutic dose (Group II) did not cause any damage in the kidney. Conclusion: N-acetylcysteine partially improves the tramadol –induced nephrotoxicity.","PeriodicalId":7627,"journal":{"name":"Al-Azhar Medical Journal","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139328742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COMPARISON OF CORONARY ARTERY PLAQUE COMPOSITION BETWEEN DIABETIC TYPE II AND NON-DIABETIC PATIENTS USING MULTISLICE CT ANGIOGRAPHY","authors":"","doi":"10.21608/amj.2023.315117","DOIUrl":"https://doi.org/10.21608/amj.2023.315117","url":null,"abstract":"","PeriodicalId":7627,"journal":{"name":"Al-Azhar Medical Journal","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135805346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A STUDY OF GLYPICAN 3 LEVELS IN PATIENTS OF HEPATO-CELLULAR CARCINOMA","authors":"","doi":"10.21608/amj.2023.315123","DOIUrl":"https://doi.org/10.21608/amj.2023.315123","url":null,"abstract":"","PeriodicalId":7627,"journal":{"name":"Al-Azhar Medical Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135805797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DETECTION OF MYOCARDIAL ISCHEMIA IN ASYMPTOMATIC PATIENTS WITH DOCUMENTED TRANSIENT ISCHEMIC ATTACKS","authors":"","doi":"10.21608/amj.2023.315125","DOIUrl":"https://doi.org/10.21608/amj.2023.315125","url":null,"abstract":"","PeriodicalId":7627,"journal":{"name":"Al-Azhar Medical Journal","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135805321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COMPARATIVE STUDY BETWEEN CONVENTIONAL AND DISTAL RADIAL ARTERY APPROACHES FOR CORONARY ANGIOGRAPHY AND/OR INTERVENTION; IMMEDIATE AND SHORT-TERM FOLLOW UP","authors":"","doi":"10.21608/amj.2023.315121","DOIUrl":"https://doi.org/10.21608/amj.2023.315121","url":null,"abstract":"","PeriodicalId":7627,"journal":{"name":"Al-Azhar Medical Journal","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135805344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Silent central nervoussystem affectionincasesofsubclinical hypothyroidism","authors":"","doi":"10.21608/amj.2023.315132","DOIUrl":"https://doi.org/10.21608/amj.2023.315132","url":null,"abstract":"","PeriodicalId":7627,"journal":{"name":"Al-Azhar Medical Journal","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135805807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}