{"title":"Back to basics: fundamental cognitive therapy skills for keeping drug-dependent individuals in treatment.","authors":"B S Liese, A T Beck","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cognitive therapists who treat drug-dependent patients are likely to lose at least 50 percent of their patients to dropout. This chapter has presented a cognitive model for conceptualizing missed sessions and dropout, along with strategies for reducing the likelihood of missed sessions and dropout. The following should serve to highlight these strategies. 1. Therapists are encouraged to offer warm, empathetic, collaborative relationships in which drug-dependent patients can feel accepted, understood, and validated. 2. Therapists are encouraged to develop comprehensive, accurate case conceptualizations, with attention paid to the potential for missed sessions and dropout. Case conceptualizations should ultimately guide cognitive and behavioral techniques. 3. Therapists are encouraged to structure sessions and elicit feedback regarding their patient's thoughts and beliefs about therapy and the therapist. This feedback is facilitated by such questions as, \"What do you like most about therapy?\" \"What do you like least?\" \"What has changed in your life as a result of therapy?\" \"How do you view our relationship?\" 4. Therapists are encouraged to socialize patients in a timely, appropriate manner. 5. Similar to the process of socialization, therapists are encouraged to use cognitive and behavioral techniques in a timely, appropriate manner. It is unrealistic to think that the problems of missed sessions and dropout from drug treatment will ever be fully resolved. Nonetheless, the authors believe that the conceptual models and fundamental strategies presented in this chapter represent a significant step in addressing these problems.</p>","PeriodicalId":76229,"journal":{"name":"NIDA research monograph","volume":"165 ","pages":"207-32"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20187203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The use of the psychological laboratory to study sensitive survey topics.","authors":"G B Willis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Maximizing the tendency of the survey respondent to answer truthfully when sensitive questions are presented is critical issue in survey methodology. A recent development devoted generally to the reduction of response error in survey data is the use of cognitive laboratory techniques during the survey development phase. The chapter categorizes and describes the various cognitive techniques that have been applied, by Federal agencies and other researchers, to the study of sensitive questions. Based on this analysis and review, a number of recommendations are made concerning specific aspects of survey design, when sensitive questions are administered.</p>","PeriodicalId":76229,"journal":{"name":"NIDA research monograph","volume":"167 ","pages":"416-38"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20186281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inhalation studies with drugs of abuse.","authors":"Y Meng, A H Lichtman, D T Bridgen, B R Martin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76229,"journal":{"name":"NIDA research monograph","volume":"173 ","pages":"201-24"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20202251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antibodies as pharmacokinetic and metabolic modifiers of neurotoxicity.","authors":"S M Owens","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76229,"journal":{"name":"NIDA research monograph","volume":"173 ","pages":"259-72"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20202253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Ling, S. Shoptaw, D. Wesson, R. Rawson, Margaret A. Compton, Klett Cj
{"title":"Treatment effectiveness score as an outcome measure in clinical trials.","authors":"W. Ling, S. Shoptaw, D. Wesson, R. Rawson, Margaret A. Compton, Klett Cj","doi":"10.1037/e495552006-011","DOIUrl":"https://doi.org/10.1037/e495552006-011","url":null,"abstract":"A variety of measures are used for evaluating patients’ responses to substance abuse treatments. These range from physical measures (such as samples of urine, breath, hair, or blood), self-reports of drug use (such as the Addiction Severity Index (ASI) or the Time Line Follow-Back), self-reports of psychological or physiological functioning (such as symptom checklists or craving or mood ratings), and collateral reports. Physical indices of recent drug use, such as urine toxicology screens, are preferable to self-report or collateral reports for evaluating patients’ responses to drug abuse treatments because of their objectivity. In order to optimize the likelihood of both detecting individual episodes of problem drug use and correctly inferring drug abstinence based on urine toxicology results, guidelines have been suggested for collection procedures and timing for collection of urine specimens (Blaine et al. 1994; Cone and Dickerson 1992; Jain 1992). However, the difficult task of aggregating urine toxicology results remains, whether when interpreting the response of a single patient to a specific treatment or when evaluating a treatment’s effectiveness based on a group of patients’ responses in a clinical trial. Difficulties in aggregating urine toxicology results include, but certainly would not be limited to, such problems as the frequency and sensitivity of toxicology screens, early termination of some patients from treatment (or, conversely, the continued participation of some patients who respond poorly to treatment), and problems of analyzing a data matrix that contains a large number of missing datapoints. This chapter reviews the objective indices of treatment response that have traditionally been used and suggests three composite methods for evaluating these data: the Treatment Effectiveness Score (TES), the Joint Probability score (JP), and the Clinical Stabilization Score (CSS).","PeriodicalId":76229,"journal":{"name":"NIDA research monograph","volume":"175 1","pages":"208-20"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57798737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cognitive-neuromotor assessment of substance abuse: focus on issues related to cocaine abuse treatment.","authors":"E. Ellinwood, T. Lee","doi":"10.1037/E495552006-010","DOIUrl":"https://doi.org/10.1037/E495552006-010","url":null,"abstract":"Choice of the procedures and types of cognitive-neuromotor testing used in assessment of cocaine abusers and their treatment is dependent on a clear definition of the purposes of testing and the characteristics of the individual tests. This chapter will first discuss published studies of testing in cocaine abusers and pharmacodynamic effects of stimulants and withdrawal. The types of tests available and their characteristics will be discussed in terms of the purpose of testing. The case will be made for the value of computerized cognitiveneuromotor testing when repeated assessment is needed in a busy clinical setting.","PeriodicalId":76229,"journal":{"name":"NIDA research monograph","volume":"175 1","pages":"192-207"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57799170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Goals and rationale for pharmacotherapeutic approach in treating cocaine dependence: insights from basic and clinical research.","authors":"M. Kreek","doi":"10.1037/e495552006-002","DOIUrl":"https://doi.org/10.1037/e495552006-002","url":null,"abstract":"The early research conducted in the author’s laboratory from 1975 onward stemmed from the even earlier work, beginning in 1964 when the author was a member of the laboratory of Professor Vincent P. Dole at the Rockefeller Institute for Biomedical Research (now the Rockefeller University) (Dole et al. 1966; Kreek 1972, 1973a; Kreek et al. 1972). At that time, scientists were challenged to develop a treatment for opiate dependency, a problem that is still being addressed, but for which there are now three different pharmacotherapeutic approaches approved by the Food and Drug Administration (FDA), and a fourth under investigation. This chapter will review briefly some of the early concepts because they are relevant for the current major problem: developing a new medication (and possibly a variety of medications) for treating cocaine dependency.","PeriodicalId":76229,"journal":{"name":"NIDA research monograph","volume":"8 1","pages":"5-35"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57798197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis With Missing Data in Prevention Research","authors":"J. Graham, S. Hofer, A. Piccinin","doi":"10.1037/10222-010","DOIUrl":"https://doi.org/10.1037/10222-010","url":null,"abstract":"Missing data problems have been a thorn in the side of prevention researchers for years. Although some solutions for these problems have been available in the statistical literature, these solutions have not found their way into mainstream prevention research. This chapter is meant to serve as an introduction to the systematic application of the missing data analysis solutions presented recently by Little and Rubin (1987) and others. The chapter does not describe a complete strategy, but it is relevant for (1) missing data analysis with continuous (but not categorical) data, (2) data that are reasonably normally distributed, and (3) solutions for missing data problems for analyses related to the general linear model in particular, analyses that use (or can use) a covariance matrix as input. The examples in the chapter come from drug prevention research. The chapter discusses (1) the problem of wanting to ask respondents more questions than most individuals can answer; (2) the problem of attrition and some solutions; and (3) the problem of special measurement procedures that are too expensive or time consuming to obtain for all subjects. The authors end with several conclusions: Whenever possible, researchers should use the Expectation-Maximization (EM) algorithm (or other maximum likelihood procedure, including the multiple-group structural equation-modeling procedure or, where appropriate, multiple imputation, for analyses involving missing data [the chapter provides concrete examples]); If researchers must use other analyses, they should keep in mind that these others produce biased results and should not be relied upon for final analyses; When data are missing, the appropriate missing data analysis procedures do not generate something out of nothing but do make the most out of the data available; When data are missing, researchers should work hard (especially when planning a study) to find the cause of missingness and include the cause in the analysis models; and Researchers should sample the cases originally missing (whenever possible) and adjust EM algorithm parameter estimates accordingly.","PeriodicalId":76229,"journal":{"name":"NIDA research monograph","volume":"142 1","pages":"13-63"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57476962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Network Theory: A Model for Understanding Drug Abuse Among African-American and Hispanic Youth","authors":"M. Krohn, T. Thornberry","doi":"10.3109/10826089709035606","DOIUrl":"https://doi.org/10.3109/10826089709035606","url":null,"abstract":"No significant differences are found in the density or multiplexity of friendship networks of adolescent drug users and non-users. However, users are more likely than non-users to have friends from the same neighborhood, to have more intimate friendship networks, and to change friends over time. Users are less likely to have friends from the same school and to have parents involved in extracurricular activities. Networks of White users and non-users are more similar than those of Hispanics or African Americans.","PeriodicalId":76229,"journal":{"name":"NIDA research monograph","volume":"32 1","pages":"1931-1936"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10826089709035606","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69564825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Sayre, D. Engelhart, D. Nadkarni, M. K. Manoj Babu, A. M. Flammang, G. Mccoy
{"title":"The role of iminium-enamine species in the toxication and detoxication of cyclic tertiary amines.","authors":"L. Sayre, D. Engelhart, D. Nadkarni, M. K. Manoj Babu, A. M. Flammang, G. Mccoy","doi":"10.1037/e495572006-009","DOIUrl":"https://doi.org/10.1037/e495572006-009","url":null,"abstract":"Aliphatic cyclic tertiary amines constitute a major class of naturally occurring and synthetic drugs directed at central biogenic amine receptors. Microsomal metabolism of these amines is known to be associated with low levels of covalent binding and/or suicide inactivation of the pertinent metabolizing P-450 isozymes; two of the more notorious examples are phencyclidine (1-(1phenylcyclohexyl)piperidine) (PCP) (Hoag et al. 1984) and nicotine (Shigenaga et al. 1988).","PeriodicalId":76229,"journal":{"name":"NIDA research monograph","volume":"173 1","pages":"106-27"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"57799776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}