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Gynecologic investigation最新文献

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Unbound unconjugated cortisol in umbilical cord and corresponding maternal plasma. Materno-fetal gradient: comparison of methods. 脐带和母体血浆中未结合的非共轭皮质醇。母胎梯度:方法的比较。
Gynecologic investigation Pub Date : 1974-01-01 DOI: 10.1159/000301652
H H Simmer, M V Frankland, M Greipel
{"title":"Unbound unconjugated cortisol in umbilical cord and corresponding maternal plasma. Materno-fetal gradient: comparison of methods.","authors":"H H Simmer, M V Frankland, M Greipel","doi":"10.1159/000301652","DOIUrl":"https://doi.org/10.1159/000301652","url":null,"abstract":"Unbound unconjugated cortisol was measured in cord venous and arterial plasma and in simultaneously obtained maternal venous plasma by equilibrium dialysis at 37 and 5 °C and by centrifugal ultrafiltration at 37 °C. Total cortisol was quantitated by a specific method based on chromatography and competitive protein binding. 67 cases were studied at cesarean section, 7 at vaginal delivery. Regardless of the method used, values of unbound cortisol in cord plasma were found to be much lower than previously reported. The values for unbound cortisol in the mothers exceed approximately 3-fold those in the newborn.","PeriodicalId":75889,"journal":{"name":"Gynecologic investigation","volume":"5 4","pages":"199-221"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000301652","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15566355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Recollections of my life with progesterone. 回忆我的黄体酮生活。
Gynecologic investigation Pub Date : 1974-01-01 DOI: 10.1159/000301649
W M Allen
{"title":"Recollections of my life with progesterone.","authors":"W M Allen","doi":"10.1159/000301649","DOIUrl":"https://doi.org/10.1159/000301649","url":null,"abstract":"This paper gives in narrative style those phases of the corpus luteum story in which the author was an active participant. The first part deals with the exciting days at the University of Rochester wh","PeriodicalId":75889,"journal":{"name":"Gynecologic investigation","volume":"5 3","pages":"142-82"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000301649","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15716640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
Experimental Mycoplasma hominis i infection in the pregnant rat. A possible model for studies of teratogenesis. 妊娠大鼠人支原体感染的实验研究。一个可能的畸胎症研究模型。
Gynecologic investigation Pub Date : 1974-01-01 DOI: 10.1159/000301633
M. Millar, C. Graber
{"title":"Experimental Mycoplasma hominis i infection in the pregnant rat. A possible model for studies of teratogenesis.","authors":"M. Millar, C. Graber","doi":"10.1159/000301633","DOIUrl":"https://doi.org/10.1159/000301633","url":null,"abstract":"Mycoplasma hominis I is known to spread systematically and to cause occasional illness in humans. M. hominis I a common commensal in the vagina of women, was used","PeriodicalId":75889,"journal":{"name":"Gynecologic investigation","volume":"5 2 1","pages":"73-82"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000301633","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65437667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The origin of human pregnancy serum oxytocinase. 人妊娠血清催产素酶的来源。
Gynecologic investigation Pub Date : 1974-01-01 DOI: 10.1159/000301660
M Oya, M Yoshino, S Mizutani, T Wakabayashi
{"title":"The origin of human pregnancy serum oxytocinase.","authors":"M Oya, M Yoshino, S Mizutani, T Wakabayashi","doi":"10.1159/000301660","DOIUrl":"https://doi.org/10.1159/000301660","url":null,"abstract":"Serial electrophoretic experiments concerning serum and placental oxytocinases were carried out with a direct staining method for cystine aminopeptidase activity. The pregnancy serum oxytocinase and the lysosomal oxytocinase in human placenta shared the same enzymatic characteristics, with regard to heat resistence, sensitivity to L-methionine inhibition and electrophoretic pattern. These similarities suggest that the possible site of production of pregnancy serum oxytocinase is the lysosomes of the placenta, from which the enzyme is released into maternal circulation during pregnancy. Absence of oxytocinase activity in fetal serum indicates that this enzyme does not leak into fetal circulation. The physiological significance of oxytocinase was discussed with special reference to the oxytocin-oxytocinase equilibrium during pregnancy and labor.","PeriodicalId":75889,"journal":{"name":"Gynecologic investigation","volume":"5 5-6","pages":"276-83"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000301660","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15563425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Growth of uterine oxygen and glucose uptakes during pregnancy in sheep. 绵羊妊娠期子宫氧和葡萄糖摄取的增长。
Gynecologic investigation Pub Date : 1974-01-01 DOI: 10.1159/000301654
F H Morriss, C R Rosenfeld, R Resnik, G Meschia, E L Makowski, F C Battaglia
{"title":"Growth of uterine oxygen and glucose uptakes during pregnancy in sheep.","authors":"F H Morriss, C R Rosenfeld, R Resnik, G Meschia, E L Makowski, F C Battaglia","doi":"10.1159/000301654","DOIUrl":"https://doi.org/10.1159/000301654","url":null,"abstract":"The growth of uterine oxygen and glucose uptakes (Qo2, Q glucose) throughout pregnancy was determined in sheep with chronically implanted uterine artery electromagnetic flow probes and arterial and uterine venous catheters. The flow probe measurements were corrected to total uterine blood flow by means of an equation based on simultaneous flow probe and radioactive microsphere determinations. Uterine Qo2, and Q glucose increased logarithmically as gestation progressed. During the last third of gestation, the mean Qo2 for twin pregnancies was 44% higher than Qo2 for single pregnancies. In the last 3 weeks of gestation the uterine glucose/oxygen quotient was 0.76 (95% confidence limits 0.65–0.87), which is significantly less than one and significantly greater than the 0.46 umbilical glucose/oxygen quotient determined in previous studies. This result indicates that substrates other than glucose are used in large amounts in order to satisfy the requirements of uterine oxidative metabolism in late pregnancy and that the placenta has a relatively high glucose/oxygen quotient. Uterine arteriovenous differences of fructose and pyruvate measured at intervals throughout gestation revealed that there is no significant uptake of these substrates by the pregnant uterus.","PeriodicalId":75889,"journal":{"name":"Gynecologic investigation","volume":"5 4","pages":"230-41"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000301654","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15566356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Use of ultrasound in the prenatal exclusion of primary microcephaly. 超声在产前排除原发性小头畸形中的应用。
Gynecologic investigation Pub Date : 1974-01-01 DOI: 10.1159/000301664
L E Karp, D W Smith, G S Omenn, S L Johnson, K Jones
{"title":"Use of ultrasound in the prenatal exclusion of primary microcephaly.","authors":"L E Karp, D W Smith, G S Omenn, S L Johnson, K Jones","doi":"10.1159/000301664","DOIUrl":"https://doi.org/10.1159/000301664","url":null,"abstract":"There are no chromosomal or biochemical abnormalities that can be used for the prenatal diagnosis of primary microcephaly. However, since scalp hair directional patterning is determined between 10 and 16 weeks of fetal life, and since at least 85% of patients with primary microcephaly show aberrant scalp hair patterning, it may be concluded that a deficit of brain growth and consequently also of head size exists by the 17th week of pregnancy. Thus, ultrasonic determination of fetal head size may permit the diagnosis or exclusion of primary microcephaly in the early second trimester of pregnancy.","PeriodicalId":75889,"journal":{"name":"Gynecologic investigation","volume":"5 5-6","pages":"311-6"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000301664","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15563428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Hormonal regulation of myometrial calcium transport. 子宫肌层钙转运的激素调节。
Gynecologic investigation Pub Date : 1974-01-01 DOI: 10.1159/000301659
M E Carsten
{"title":"Hormonal regulation of myometrial calcium transport.","authors":"M E Carsten","doi":"10.1159/000301659","DOIUrl":"https://doi.org/10.1159/000301659","url":null,"abstract":"Purified preparations of fragmented sarcoplasmic reticulum from non-pregnant bovine uterus bind calcium from a medium containing ATP and Mg++. This calcium binding was enhanced in the presence of progesterone, while it is decreased in the presence of oxytocin. In the presence of both hormones there was an intermediate effect. PGF2Α, when added to preparations that had previously bound calcium in the presence of progesterone, caused release of limited amounts of calcium. Under these conditions calcium binding was much higher than that observed in the presence of PGF2Α alone. Three steroid analogs showed no effect on ATP-dependent calcium binding.","PeriodicalId":75889,"journal":{"name":"Gynecologic investigation","volume":"5 5-6","pages":"269-75"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000301659","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15563424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 36
Fetal lung maturation. I. Phosphatidic acid phosphohydrolase in rabbit lung. 胎儿肺成熟。1 .兔肺磷脂酸磷酸水解酶。
Gynecologic investigation Pub Date : 1974-01-01
F M Schultz, J M Jimenez, P C MacDonald, J M Johnston
{"title":"Fetal lung maturation. I. Phosphatidic acid phosphohydrolase in rabbit lung.","authors":"F M Schultz, J M Jimenez, P C MacDonald, J M Johnston","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75889,"journal":{"name":"Gynecologic investigation","volume":"5 4","pages":"222-9"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15481048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of sympathetic denervation of the rabbit oviduct on normal ovum transport and on transport modified by estrogen and progesterone. 兔输卵管交感神经去支配对正常卵子运输及雌激素、黄体酮介导的转运的影响。
Gynecologic investigation Pub Date : 1974-01-01 DOI: 10.1159/000301646
C J Pauerstein, B J Hodgson, B D Fremming, J E Martin
{"title":"Effects of sympathetic denervation of the rabbit oviduct on normal ovum transport and on transport modified by estrogen and progesterone.","authors":"C J Pauerstein, B J Hodgson, B D Fremming, J E Martin","doi":"10.1159/000301646","DOIUrl":"https://doi.org/10.1159/000301646","url":null,"abstract":"Oviducts were depleted of endogenous sympathetic neurotransmitter by either surgical denervation, or intraluminal infusion of 6-OH-dopamine or systemic administration of reserpine. Functional denervation was confirmed by histochemical examination of the oviducts. These procedures failed to disrupt normal transport rates of ova as indicated by oviductal ovum recovery rates at 48 and 72 h following HCG injection. However, estrogen-induced ‘tube-locking’ of ova and progesterone-induced acceleration of ovum transport were partially antagonized by depletion of neurotransmitter from the intrinsic adrenergic nerves of the oviduct. These data suggest that the effects of sex steroids on ovum transport are partially mediated through adrenergic processes.","PeriodicalId":75889,"journal":{"name":"Gynecologic investigation","volume":"5 3","pages":"121-32"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000301646","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15264349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
The early history of progesterone. 黄体酮的早期历史。
Gynecologic investigation Pub Date : 1974-01-01 DOI: 10.1159/000301641
G W Corner
{"title":"The early history of progesterone.","authors":"G W Corner","doi":"10.1159/000301641","DOIUrl":"https://doi.org/10.1159/000301641","url":null,"abstract":"The corpus luteum was first clearly described by Regner de Graaf (1672). That it is an organ of internal secretion was suggested by Louis-Auguste Prenant in 1898 and by Gustav Born about the same time","PeriodicalId":75889,"journal":{"name":"Gynecologic investigation","volume":"5 2","pages":"106-12"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000301641","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15712185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 33
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