Environmental physiology & biochemistry最新文献_第4页

Biochemical effects of di-2-ethylhexyl phthalate. 邻苯二甲酸二-2-乙基己酯的生化效应。

Environmental physiology & biochemistry Pub Date : 1975-01-01

S P Srivastava, P K Seth, D K Agarwal

引用次数: 0

Glutamine synthetase, glutaminase and phosphodiesterase activities in brain under hypoxia: in vitro effect of cortisol, GABA and serotonin on glutamine synthetase. 缺氧条件下脑内谷氨酰胺合成酶、谷氨酰胺酶和磷酸二酯酶活性:皮质醇、GABA和血清素对谷氨酰胺合成酶的体外影响

Environmental physiology & biochemistry Pub Date : 1975-01-01

V P Chandrasekaran, R Viswanathan, T A Venkitasubramanian

引用次数: 0

Steroidogenesis in vitro in the harp seal (Pagophilus groenlandicus) without and with methyl mercury treatment in vivo. 在体内不加甲基汞处理和加甲基汞处理的竖琴海豹体外甾体形成。

Environmental physiology & biochemistry Pub Date : 1975-01-01

H C Freeman, G Sangalang, J F Uthe, K Ronald

{"title":"Steroidogenesis in vitro in the harp seal (Pagophilus groenlandicus) without and with methyl mercury treatment in vivo.","authors":"H C Freeman, G Sangalang, J F Uthe, K Ronald","doi":"","DOIUrl":"","url":null,"abstract":"Tissue from a harp seal given methyl mercury at a concentration of 0.25 mg/kg in its diet for 61 days, was highly contaminated with mercury. Over 70% of the mercury in the seal's liver (64.0 p.p.m.) was in the inorganic form indicating a demethylating system in this organ. Most of the mercury in the liver, spleen and kidney of an untreated seal was also in the inorganic form. In contrast, over 75% of the mercury in the adrenals and gonads (14.2 and 13.0 p.p.m., respectively) of the treated seal was methyl mercury. Mercury was not detectable in the gonads and not analyzed in the adrenals of the untreated seal. Biosynthesized (in vitro) cortisol, corticosterone, cortisone, and 11-ketotestosterone were isolated and identified from the adrenal incubations, and delta4-androstene-3,17-dione and testosterone were isolated and identified from ovarian incubations from both untreated and methyl mercury (in vivo) treated seals. The ovaries and adrenals from both seals appeared to be normal under the light microscope. The ovaries from both seals were in the same follicular phase, but in vitro incubations of tissue from these organs indicated that the methyl mercury and treatment caused a marked alteration of steroid biosynthesis in tissue from the treated seal. The altered pattern of steroid biosynthesis was also demonstrated by autoradiography, and it is suggested that this technique could be used as an indicator of incipient contamination by a pollutant.","PeriodicalId":75826,"journal":{"name":"Environmental physiology & biochemistry","volume":"5 6","pages":"428-39"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12388669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The distribution and biological half-time of 203Hg in the human body according to a modified whole-body counting technique. 根据改进的全身计数技术研究203Hg在人体内的分布和生物半衰期。

Environmental physiology & biochemistry Pub Date : 1975-01-01

T Hattula, T Rahola

{"title":"The distribution and biological half-time of 203Hg in the human body according to a modified whole-body counting technique.","authors":"T Hattula, T Rahola","doi":"","DOIUrl":"","url":null,"abstract":"The distribution and biological half-life of 203Hg in the human body was investigated using 203Hg-labeled compounds and a regional whole-body counting technique. Fifteen volunteers were administered methylmercury as a labeled fish proteinate. A single serving of the proteinate contained an average of 1.8 uCi of 203Hg-activity and 22 mug of total mercury. Inorganic mercury was given to eight volunteers as labeled calf liver paste containing 4-8 muCi of inorganic 203Hg-activity and 6 mug of total mercury. The radiomercury determinations were performed in a steel room equipped with the standard chair geometry and one 4 inch x 8 inch NaI(Tl) crystal. For determinations of 203Hg-activity in the head a 3 inch x 3 inch NaI(Tl) crystal was used. A lead collar was utilized as a shield in order to absorb any disturbing radiation that might originate in the stomach region. The effectiveness of the Pb collar was determined using phantoms. The activities in the whole-body, the head, the legs and the liver were determined. About 20% of the methylmercury activity in the whole-body was found to be localized in the head 30 d after administration. No significant amounts of 203Hg-activity were found in the head during the first 58 d after administration of inorganic mercury. An average value of 10-15% methylmercury activity was found in the legs 30 d after administration. A control mean value of 13% was determined by measuring five of the same volunteers the next day in Sweden. Not more than 1% of inorganic mercury was found in leg muscle after 39 d in one male volunteer. The biological half-life of protein-bound inorganic mercury in the liver region, studied in one male volunteer, was estimated at 53 +/- 15 d.","PeriodicalId":75826,"journal":{"name":"Environmental physiology & biochemistry","volume":"5 4","pages":"252-7"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11996975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiac anoxia tolerance of carbon monoxide-poisoned, hypoxia-exposed and normal rats. 一氧化碳中毒、低氧暴露及正常大鼠心脏缺氧耐受性。

Environmental physiology & biochemistry Pub Date : 1975-01-01

D Penney, M Benjamin, L Bugaisky

引用次数: 0

Effect of dieldrin toxicity on acetate and palmitate metabolism in rat liver. 狄氏剂毒性对大鼠肝脏醋酸酯和棕榈酸酯代谢的影响。

Environmental physiology & biochemistry Pub Date : 1975-01-01

K K Kohli, S C Bhatia, T A Venkitasubramanian

引用次数: 0

Effects of a polychlorinated biphenyl (PCB) on sleeping times, plasma corticosteroids, and testicular activity of white-footed mice. 多氯联苯(PCB)对白足小鼠睡眠时间、血浆皮质激素和睾丸活性的影响。

Environmental physiology & biochemistry Pub Date : 1975-01-01

O T Sanders, R L Kirkpatrick