{"title":"[Oral cancer. Prognostic aspects].","authors":"M Bryne, P S Thrane, O Schreurs, E Dabelsteen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The present knowledge regarding growth and progression of intraoral squamous cell carcinoma is still fragmentary. The 5-year survival for these patients is poor. In order to improve the prognosis in this highly lethal cancer, it is important to gain more knowledge about its biological behaviour. In the present paper we suggest that certain cells at the invasive margins of the tumors are most important for prognostic evaluation of the cancer. We have studied the expression of a group of cell membrane bound carbohydrates (blood group antigens) on these deep, invasive cells and found an association between loss of expression of one of these structures and invasion and spread of the cancer cells. Furthermore, we have found a hitherto not reported prognostic value of Rhesus blood groups. We suggest that chromosome instability reported to occur on chromosome 1 in some oral squamous cell carcinomas in some way involve the Rhesus gene that is located in the same area of chromosome 1.</p>","PeriodicalId":75780,"journal":{"name":"Den Norske tannlaegeforenings tidende","volume":"101 10","pages":"338-42"},"PeriodicalIF":0.0,"publicationDate":"1991-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13105510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Calcium fluoride or not? That is the question!].","authors":"B Ogaard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The relative cariostatic effect of fluoride as fluorapatite, calcium fluoride-like material, loosely bound fluoride or KOH-soluble fluoride is debated. The present study was carried out to investigate this further in an intraoral caries model. Pair of premolars extracted for orthodontic reasons were used. Enamel from one tooth of each pair was used as controls (untreated). Two slabs were cut from the enamel of the other contralateral premolar. These slabs were treated with 2% NaF for 24 h. One slab was then treated with 1 mol/L KOH for 24 h to remove all loosely bound fluoride. The slabs treated with 2% NaF and then 1 mol/L KOH would contain the KOH-insoluble fluoride. Those treated with only 2% NaF would, in addition, contain KOH-soluble fluoride. Each slab, control, KOH-insoluble F and KOH-soluble and insoluble F, was mounted on different upper removable appliances. The slabs were covered with orthodontic banding material, allowing space for plaque accumulation. Five individuals wore the appliances in 3 separate 4-week periods. The slabs were analyzed by quantitative microradiography. The average mineral loss (delta Z) was 1680 +/- 1000 vol% z microns in the control teeth, 620 +/- 76 vol% . microns in the KOH-soluble and insoluble F teeth and 2167 +/- 1278 vol% . microns in the KOH-insoluble F teeth. The average lesion depths were 90 +/- 41 microns in the control teeth, 35.3 +/- 5.5 microns in the KOH-soluble F teeth and 88 +/- 35 microns in the KOH-insoluble F teeth. It was concluded that only KOH-soluble fluoride reduced mineral loss and lesion depths significantly compared with the untreated teeth.</p>","PeriodicalId":75780,"journal":{"name":"Den Norske tannlaegeforenings tidende","volume":"101 9","pages":"304-7"},"PeriodicalIF":0.0,"publicationDate":"1991-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13105514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The mentally retarded and the dental health services. Treatment needs and preventive strategies].","authors":"K Storhaug","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Mentally retarded individuals are, since 1984 a priority group for the Norwegian public dental health service. This group of patients may have many problems which affect oral health. Difficulties with feeding are common, as are various oral motor problems like rumination, bruxism, mouth breathing and drooling. The impaired oral function may cause retention of food, reduced self-cleaning from lips and tongue and long-term use of puree food. Obstipation is a common problem which is often treated with prunes, raisins or sweetened laxatives. In behaviour modification programs sweets are often used as rewards. Tooth cleaning may cause problems for many parents and caretakers due to lack of cooperation or anatomical malformation of oral structures or teeth. Dental treatment may also be difficult to perform. Recent research in Nordic countries supports earlier reports that mentally retarded individuals have a high incidence of plaque, periodontal disease and malocclusion. Caries does not seem to be a problem. Nevertheless, older individuals with mental retardation have more untreated caries and missing teeth than average. Early intervention with oral motor training and frequent regular preventive treatment (4 x per year) will reduce caries, periodontal disease, early tooth loss and the need for treatment under general anesthesia in the future.</p>","PeriodicalId":75780,"journal":{"name":"Den Norske tannlaegeforenings tidende","volume":"101 8","pages":"262-5"},"PeriodicalIF":0.0,"publicationDate":"1991-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12996260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The mentally retarded dental patients. Who are they?].","authors":"K Storhaug","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>More than 30,000 Norwegians are mentally retarded and about 50% of them are severely retarded and often multihandicapped. Before 1975 the majority of the severely retarded resided in large institutions. New legislation has led to an increasing emphasis on decentralization and integration in local communities. Mental retardation is caused by prenatal brain damage in 90% of the cases. Chromosomal aberrations like Down and Fragile-X syndromes are the most common causes. A high proportion of individuals with autism, cerebral palsy, epilepsy and sensory defects are mentally retarded, and the most common additional diagnoses in mental retardation are speech defects, epilepsy, cerebral palsy, congenital heart disease, sight and hearing impairment and hydrocephalus. Almost 1/3 of the mentally retarded adults have developed psychiatric disturbances. Families with mentally retarded children are affected emotionally, socially and economically, and the burden increases as the mentally retarded individual grows older.</p>","PeriodicalId":75780,"journal":{"name":"Den Norske tannlaegeforenings tidende","volume":"101 8","pages":"258-61"},"PeriodicalIF":0.0,"publicationDate":"1991-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12996259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Possible limitations in the caries preventive effect of fluorides?].","authors":"B Ogaard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The cariostatic effect of fluoride at different levels of pH in the plaque fluid is discussed. At the pH level 5.5 to 4.5 the plaque fluid is undersaturated with respect to hydroxyapatite and supersaturated with respect to fluorapatite (3). The hydroxyapatite of the enamel then dissolves. With fluoride present in the liquid phase a fluoridated apatite is precipitated in the surface zone of the lesion. In acidic, old plaque the plaque fluid is very likely undersaturated also with respect to fluorapatite (pH less than 4.5) (11). When the liquid phase is undersaturated with respect to fluorapatite no redeposition of mineral lost can occur. In due time an erosion will develop. It is speculated that one reason for the minor effect of fluoride in some caries active patients and in fissures as well is that the plaque fluid is undersaturated with respect to fluorapatite for extended periods.</p>","PeriodicalId":75780,"journal":{"name":"Den Norske tannlaegeforenings tidende","volume":"101 6","pages":"176-80"},"PeriodicalIF":0.0,"publicationDate":"1991-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12816487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Allogeneic transplantation--two case reports].","authors":"K Bjorvatn, A G Grönningsaeter, H Vindenes","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After a brief discussion on the transplantation of teeth, two cases of allogeneic transplantation, respectively from brother to sister, and from daughter to mother, are presented. Based on the two cases and a limited number of case histories found in dental literature, it is suggested that immunological screening of donor and recipient may help improve the prognosis of allogeneic transplantation of teeth.</p>","PeriodicalId":75780,"journal":{"name":"Den Norske tannlaegeforenings tidende","volume":"101 6","pages":"182-7"},"PeriodicalIF":0.0,"publicationDate":"1991-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13022302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Cariological conditions in patients in a psychiatric hospital in Norway].","authors":"B Ogaard, I J Koxvig","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The caries status was recorded for 107 patients in a Norwegian psychiatric hospital in 1988. The number of edentulous patients was highest among patients older than 50 years (42%). Only two patients below 50 years of age were edentulous (5%). The average DMFT was 21.5 in the age group below 50 years and 26.8 in the age group above 50 years. The percentage number of patients with carious teeth (DT greater than 0) was 42% in those above 50 years and 60% in those below 50 years of age. On average, each patients used nearly 3 medicaments regularly. Most of the medicaments belonged to the antidepressiva and neuroleptica group which give nearly complete xerostomia. It is speculated that the reason for the high caries activity in the hospitalized psychiatric patients is due to irregular eating and oral hygiene habits in combination with complete or partial xerostomia. It is suggested that fluoride therapy (topical and tablets) and professional plaque control would be the most appropriate preventive measures.</p>","PeriodicalId":75780,"journal":{"name":"Den Norske tannlaegeforenings tidende","volume":"101 5","pages":"144-7"},"PeriodicalIF":0.0,"publicationDate":"1991-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12991525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Dental health and the use of dental services among Norwegian recruits in 1988].","authors":"O Asmyhr, J V Nielsen, P W Norheim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of the present study was to describe dental health and dental health behaviour among Norwegian recruits. Data were collected by questionnaires and clinical and radiological examinations among 1067 recruits in 1988. 23.7% of all recruits had no decayed teeth. The average DMFT score was 12.1 (SD = 4.69) and the number of decayed surfaces was 4.1 (SD = 5.97), 46.1% of all recruits had visited the dentist during the last year. The clinical findings (except x-ray scores) were compared with findings from similar studies in 1968 and 1978. The results showed that the dental health improved from 1968 to 1988, while the treatment need was similar in 1978 and 1988. There was little change in the regular dental attendance pattern from 1968 to 1988.</p>","PeriodicalId":75780,"journal":{"name":"Den Norske tannlaegeforenings tidende","volume":"101 4","pages":"108-10"},"PeriodicalIF":0.0,"publicationDate":"1991-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13022300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Heyden, S P Lyngstadaas, P S Thrane, P Brandtzaeg
{"title":"[Can virus cause oral cancers?].","authors":"A Heyden, S P Lyngstadaas, P S Thrane, P Brandtzaeg","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Tumour viruses are thought to contribute to the development of one fifth of all human cancers, although the mechanisms involved are still obscure. Human papilloma virus (HPV) is a DNA virus associated with oral carcinomas. It has been shown that virus DNA has to become integrated into cellular DNA in order to transform normal to malignant cells. Cellular oncogenes and tumour suppressor genes are potential cancer genes. They are involved in the control of growth and differentiation of normal cells. It is known that structural or regulatory changes (activation) of these genes will lead to malignant transformation. Virus integration will sometimes take place in close relation to cellular oncogenes. Such incorporation may result in oncogene activation. Other cellular factors that may contribute to the development of oral squamous cell carcinoma are also discussed.</p>","PeriodicalId":75780,"journal":{"name":"Den Norske tannlaegeforenings tidende","volume":"101 4","pages":"104-7"},"PeriodicalIF":0.0,"publicationDate":"1991-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12816486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Loss of permanent upper incisors--orthodontic treatment].","authors":"K Thunold","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After loss of permanent central incisors the treatment of choice could be either orthodontic closure or maintenance of the gap for a replacement-prosthetic, autotransplantation or implant. Cases suitable for orthodontic closure are Angle C1 I space deficiency cases and some C1 II cases, all of these requiring normal size and shape of the lateral. C1 III cases, cases with completely developed ideal occlusion and cases with excess of space are unsuitable for orthodontic closure, as are small pegshaped laterals. Different treatment alternatives are presented, illustrated with treated cases. When one or two central incisors are missing, there will be no treatment alternative giving a 100% satisfactory result. Orthodontic closure, however, proves to be a favourable solution, concerning both long-term prognosis, esthetics and function.</p>","PeriodicalId":75780,"journal":{"name":"Den Norske tannlaegeforenings tidende","volume":"101 5","pages":"134-42"},"PeriodicalIF":0.0,"publicationDate":"1991-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13022301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}