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Current topics in molecular endocrinology最新文献

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In vitro binding and autoradiographic localization of human chorionic gonadotropin and follicle stimulating hormone in rat testes during development. 人绒毛膜促性腺激素和促卵泡激素在大鼠睾丸发育过程中的体外结合和放射自显像定位。
Current topics in molecular endocrinology Pub Date : 1974-01-01 DOI: 10.1007/978-1-4684-2595-6_13
C Desjardins, A J Zeleznik, A R Midgley, L E Reichert
{"title":"In vitro binding and autoradiographic localization of human chorionic gonadotropin and follicle stimulating hormone in rat testes during development.","authors":"C Desjardins, A J Zeleznik, A R Midgley, L E Reichert","doi":"10.1007/978-1-4684-2595-6_13","DOIUrl":"https://doi.org/10.1007/978-1-4684-2595-6_13","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"1 ","pages":"221-35"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15480315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 32
Apparent positive cooperativity in the mechanism of action of luteinizng hormone. 促黄体生成素的作用机制有明显的正协同作用。
Current topics in molecular endocrinology Pub Date : 1974-01-01 DOI: 10.1007/978-1-4684-2595-6_4
D Rodbard, W Moyle, J Ramanchandran
{"title":"Apparent positive cooperativity in the mechanism of action of luteinizng hormone.","authors":"D Rodbard,&nbsp;W Moyle,&nbsp;J Ramanchandran","doi":"10.1007/978-1-4684-2595-6_4","DOIUrl":"https://doi.org/10.1007/978-1-4684-2595-6_4","url":null,"abstract":"<p><p>In vitro accumulation of cyclic AMP by rat Leydig cell preparation and mouse tumor Leydig cells in response to exogenous LH appears to display an apparent Hill coefficient of 2.5. This is suggestive of positive cooperativity at a level intermediate between binding and cyclic AMP production, although several alternative hypothesis cannot be excluded on the basis of these data alone. The Hill coefficient for testosterone is higher than unity, although it has not been established with adequate precision in these experiments.</p>","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"1 ","pages":"79-87"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15483936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The production of androgen binding protein by Sertoli Cells. 支持细胞雄激素结合蛋白的产生。
Current topics in molecular endocrinology Pub Date : 1974-01-01 DOI: 10.1007/978-1-4684-2595-6_9
D J Tindall, W T Schrader, A R Means
{"title":"The production of androgen binding protein by Sertoli Cells.","authors":"D J Tindall,&nbsp;W T Schrader,&nbsp;A R Means","doi":"10.1007/978-1-4684-2595-6_9","DOIUrl":"https://doi.org/10.1007/978-1-4684-2595-6_9","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"1 ","pages":"167-75"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15575350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 31
FSH receptors in rat testis: chemical properties and solubilization studies. 大鼠睾丸中卵泡刺激素受体:化学性质和增溶性研究。
Current topics in molecular endocrinology Pub Date : 1974-01-01 DOI: 10.1007/978-1-4684-2595-6_12
V K Bhalla, L E Reichert
{"title":"FSH receptors in rat testis: chemical properties and solubilization studies.","authors":"V K Bhalla,&nbsp;L E Reichert","doi":"10.1007/978-1-4684-2595-6_12","DOIUrl":"https://doi.org/10.1007/978-1-4684-2595-6_12","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"1 ","pages":"201-20"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15480314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
The effects of FSH on cell preparations from the rat testis. 卵泡刺激素对大鼠睾丸细胞制备的影响。
Current topics in molecular endocrinology Pub Date : 1974-01-01 DOI: 10.1007/978-1-4684-2595-6_14
J H Dorrington, N F Roller, I B Fritz
{"title":"The effects of FSH on cell preparations from the rat testis.","authors":"J H Dorrington,&nbsp;N F Roller,&nbsp;I B Fritz","doi":"10.1007/978-1-4684-2595-6_14","DOIUrl":"https://doi.org/10.1007/978-1-4684-2595-6_14","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"1 ","pages":"237-41"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15480316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 24
Evidence for multiple, cell specific, distinctive adenylate cyclase systems in rat testis. 大鼠睾丸中存在多种细胞特异性腺苷酸环化酶系统的证据。
Current topics in molecular endocrinology Pub Date : 1974-01-01 DOI: 10.1007/978-1-4684-2595-6_15
T Braun
{"title":"Evidence for multiple, cell specific, distinctive adenylate cyclase systems in rat testis.","authors":"T Braun","doi":"10.1007/978-1-4684-2595-6_15","DOIUrl":"https://doi.org/10.1007/978-1-4684-2595-6_15","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"1 ","pages":"243-64"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15480317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Gonadotroping binding and activation of the interstitial cells of the testis. 促性腺激素结合和睾丸间质细胞的活化。
Current topics in molecular endocrinology Pub Date : 1974-01-01 DOI: 10.1007/978-1-4684-2595-6_1
K J Catt, T Tsuruhara, C Mendelson, J M Ketelslegers, M L Dufau
{"title":"Gonadotroping binding and activation of the interstitial cells of the testis.","authors":"K J Catt,&nbsp;T Tsuruhara,&nbsp;C Mendelson,&nbsp;J M Ketelslegers,&nbsp;M L Dufau","doi":"10.1007/978-1-4684-2595-6_1","DOIUrl":"https://doi.org/10.1007/978-1-4684-2595-6_1","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"1 ","pages":"1-30"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15480306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 50
Studies on the correlation between androgen binding and activation of rat epididymal tubules in culture. 雄激素结合与培养大鼠附睾小管活化的相关性研究。
Current topics in molecular endocrinology Pub Date : 1974-01-01 DOI: 10.1007/978-1-4684-2595-6_20
J A Blaquier, M S Cameo, R Calandra
{"title":"Studies on the correlation between androgen binding and activation of rat epididymal tubules in culture.","authors":"J A Blaquier,&nbsp;M S Cameo,&nbsp;R Calandra","doi":"10.1007/978-1-4684-2595-6_20","DOIUrl":"https://doi.org/10.1007/978-1-4684-2595-6_20","url":null,"abstract":"<p><p>Rat epididymal tubules maintained in organ culture for 3 or 7 days in media containing androgen showed a marked increase in the incorporation of radioactive amino acids and uridine into acid insoluble material. When the tubules were exposed to these hormones for brief periods, the incorporation of precursors was inhibited initially. In studying the time course of binding of 3H testosterone to the cytoplasmic receptor, a significant amount of radioactivity bound to the receptor was detected only after 12 hr of exposure to the hormone which increased three-fold after 24 hr. The time lag in the binding corresponded closely to the shortest times of observed hormone action wherein a significant increase in the incoporation of uridine (16 hr) and amino acids (24 hr) was produced. Evidence is presented demonstrating that testosterone is bound with high affinity by components of the fetal calf serum present in the culture medium.</p>","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"1 ","pages":"329-41"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15579615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Functional groups in ovine luteinizing hormone and their receptor site interactions-a chemical study. 羊黄体生成素中的官能团及其受体位点相互作用的化学研究。
Current topics in molecular endocrinology Pub Date : 1974-01-01 DOI: 10.1007/978-1-4684-2595-6_5
W K Liu, K P Yang, B D Burleigh, D N Ward
{"title":"Functional groups in ovine luteinizing hormone and their receptor site interactions-a chemical study.","authors":"W K Liu,&nbsp;K P Yang,&nbsp;B D Burleigh,&nbsp;D N Ward","doi":"10.1007/978-1-4684-2595-6_5","DOIUrl":"https://doi.org/10.1007/978-1-4684-2595-6_5","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"1 ","pages":"89-108"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15483937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Computer analysis of the binding reaction between hCG and gonadotropin receptors of the rat testis. 大鼠睾丸hCG与促性腺激素受体结合反应的计算机分析。
Current topics in molecular endocrinology Pub Date : 1974-01-01 DOI: 10.1007/978-1-4684-2595-6_2
J M Ketelslegers, G D Knott, K J Catt
{"title":"Computer analysis of the binding reaction between hCG and gonadotropin receptors of the rat testis.","authors":"J M Ketelslegers,&nbsp;G D Knott,&nbsp;K J Catt","doi":"10.1007/978-1-4684-2595-6_2","DOIUrl":"https://doi.org/10.1007/978-1-4684-2595-6_2","url":null,"abstract":"","PeriodicalId":75766,"journal":{"name":"Current topics in molecular endocrinology","volume":"1 ","pages":"31-45"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15480318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
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