{"title":"Carbon tetrachloride hepatotoxicity: an example of lethal cleavage.","authors":"R O Rechnagel, E A Glende","doi":"10.3109/10408447309082019","DOIUrl":"https://doi.org/10.3109/10408447309082019","url":null,"abstract":"","PeriodicalId":75752,"journal":{"name":"CRC critical reviews in toxicology","volume":"2 3","pages":"263-97"},"PeriodicalIF":0.0,"publicationDate":"1973-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10408447309082019","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15461104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Control of potential hazards in the environment.","authors":"R Henderson","doi":"10.3109/10408447309082018","DOIUrl":"https://doi.org/10.3109/10408447309082018","url":null,"abstract":"","PeriodicalId":75752,"journal":{"name":"CRC critical reviews in toxicology","volume":"2 3","pages":"257-62"},"PeriodicalIF":0.0,"publicationDate":"1973-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10408447309082018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15686429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultraviolet radiation as a cause of skin tumors.","authors":"E A Emmett","doi":"10.3109/10408447309025703","DOIUrl":"https://doi.org/10.3109/10408447309025703","url":null,"abstract":"","PeriodicalId":75752,"journal":{"name":"CRC critical reviews in toxicology","volume":"2 2","pages":"211-55"},"PeriodicalIF":0.0,"publicationDate":"1973-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10408447309025703","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15691860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Placental metabolism in relation to toxicology.","authors":"M R Juchau","doi":"10.3109/10408447309025701","DOIUrl":"https://doi.org/10.3109/10408447309025701","url":null,"abstract":"","PeriodicalId":75752,"journal":{"name":"CRC critical reviews in toxicology","volume":"2 2","pages":"125-58"},"PeriodicalIF":0.0,"publicationDate":"1973-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10408447309025701","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15686905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interaction of bacterial toxins in the toxicity of chemotherapeutic agents.","authors":"W C Rose","doi":"10.3109/10408447309025702","DOIUrl":"https://doi.org/10.3109/10408447309025702","url":null,"abstract":"","PeriodicalId":75752,"journal":{"name":"CRC critical reviews in toxicology","volume":"2 2","pages":"159-209"},"PeriodicalIF":0.0,"publicationDate":"1973-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10408447309025702","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15691859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The new field of plastics toxicology--methods and results.","authors":"J Autian","doi":"10.1080/10408447309163830","DOIUrl":"https://doi.org/10.1080/10408447309163830","url":null,"abstract":"A large number of medical, dental, and pharmaceutical advancements have been made with the use of new plastic materials for a host of items and devices, ranging from artificial heart valves to specialized packaging systems for the storago and delivery of medications. In the past, many of these devices and items received little attention in regard to potential toxicologic effects upon patients. Since present medical devices are not considered to be “new drugs,” there is great confusion as to the types of preclinical tests which should be performed on these items to ensure the safety of the device. A proper program to evaluate the toxicogenic properties of a material to be used in a medical and paramedical application must, of course, consider the end use of the device. In general, however, test results are needed which will indicate that (1) no toxic ingredient from a plastic will be released to tissue, (2) the released ingredient will not produce an allergic response, and (3) the released agent will not b...","PeriodicalId":75752,"journal":{"name":"CRC critical reviews in toxicology","volume":"2 1","pages":"1-40"},"PeriodicalIF":0.0,"publicationDate":"1973-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10408447309163830","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15306883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The alveolar macrophage and its role in toxicology.","authors":"D H Bowden","doi":"10.1080/10408447309163832","DOIUrl":"10.1080/10408447309163832","url":null,"abstract":"","PeriodicalId":75752,"journal":{"name":"CRC critical reviews in toxicology","volume":"2 1","pages":"95-124"},"PeriodicalIF":0.0,"publicationDate":"1973-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10408447309163832","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15456561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The acceptable daily intake of food additives.","authors":"E J Bigwood","doi":"10.1080/10408447309163831","DOIUrl":"https://doi.org/10.1080/10408447309163831","url":null,"abstract":"The Joint FAGWHO Expert Committee on Food Additives has evaluated in the past 15 years the acceptable daily intake of more than 200 food additives. This outstanding piece of work of major importance has marked a turning point in the field of the national and international public health policies concerning the control of the use of food additives and consequently the control also of food quality. It is of major importance therefore that the validity of such evaluations be fully recognized in scientific quarters. Because of certain aspects of the concept, namely the double range of safety margin of acceptable tolerance levels of these constituents in food, one unconditional and the other conditional, some doubt regarding the validity of the concept is liable to arise. A critical analysis of this aspect of the question is made, leading to the suggestion that with the exception of possibly a few cases, this double range of acceptability of an additive might usefully be dropped. At the same time a few other as...","PeriodicalId":75752,"journal":{"name":"CRC critical reviews in toxicology","volume":"2 1","pages":"41-93"},"PeriodicalIF":0.0,"publicationDate":"1973-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10408447309163831","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15822752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The two faces of selenium--can selenophobia be cured?","authors":"D V Frost","doi":"10.3109/10408447209103467","DOIUrl":"https://doi.org/10.3109/10408447209103467","url":null,"abstract":"","PeriodicalId":75752,"journal":{"name":"CRC critical reviews in toxicology","volume":"1 4","pages":"467-514"},"PeriodicalIF":0.0,"publicationDate":"1972-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10408447209103467","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15667460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Old and new issues in the safety evaluation of cosmetics and toiletries.","authors":"R P Giovacchini","doi":"10.3109/10408447209103464","DOIUrl":"https://doi.org/10.3109/10408447209103464","url":null,"abstract":"","PeriodicalId":75752,"journal":{"name":"CRC critical reviews in toxicology","volume":"1 4","pages":"361-78"},"PeriodicalIF":0.0,"publicationDate":"1972-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10408447209103464","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15667459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}