{"title":"Septic renal vein thrombosis complicated by septic pulmonary embolism.","authors":"Fahad M Iqbal, Kamel Sadat, Joel B Spear","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 36-year-old HIV-infected man admitted with a possible pyelonephritis of the left kidney and a 3.5 cm thrombus of the left renal vein developed sudden onset of dyspnea. Multiple cavitating nodules revealed under CT were aspirated yielding purulent fluid. MRSA isolates, from both the lung and blood had identical susceptibility patterns. The patient failed to respond to antibiotics until intravenous heparin was begun.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"36 ","pages":"14-7"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29594315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heparin-induced thrombocytopenia and thrombosis.","authors":"Abid Butt, Wilbert S Aronow, Dipak Chandy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Heparin-induced thrombocytopenia is an uncommon manifestation of a very commonly used drug. It can lead to catastrophic complications, especially if appropriate therapy is not initiated. This article reviews the pathophysiology, diagnosis, and management of this important topic.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"36 ","pages":"23-7"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29594319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chandra S Chilappa, Wilbert S Aronow, Deborah Shapiro, Kirk Sperber, Umesh Patel, Julia Y Ash
{"title":"Gout and hyperuricemia.","authors":"Chandra S Chilappa, Wilbert S Aronow, Deborah Shapiro, Kirk Sperber, Umesh Patel, Julia Y Ash","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hyperuricemia is an elevated uric acid level in blood. Gout is a common systemic metabolic disease characterized by deposition of monosodium urate monohydrate crystals with resultant acute intense inflammation of the involved joint. The clinical spectrum ranges from asymptomatic hyperuricemia to intermittent acute episodes of gouty arthritis to chronic tophaceous gout and chronic gouty arthropathy.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"36 ","pages":"3-13"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29594314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Genetics of cardiovascular disease.","authors":"Tyler Cymet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It is often assumed that cardiovascular disease is due to issues related to lifestyle. While lifestyle does contribute to the expression of cardiovascular issues, a genetic etiology to Marfan's syndrome, hypertrophic cardiomyopathy and long QT syndrome have been shown. It is unclear as to what role genetics plays in hypertension and hyperlipidemia, although it is felt that genetics contributes to these pathologies as well.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"36 ","pages":"18-9"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29594316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antiplatelet therapy in cardiovascular disease.","authors":"Syed M Ahmed, Edward L O'Leary, L A Innone","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Antiplatelet therapy has an essential role in the treatment of cardiovascular disease. In this article, we discuss the characteristics of current, new and emerging antiplatelet drugs, their mechanisms of action, and their role in the primary and secondary prevention of cardiovascular disease.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"36 ","pages":"20-2"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29594317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Comprehensive therapyPub Date : 2009-10-01DOI: 10.1378/CHEST.136.4_MEETINGABSTRACTS.106S-A
Sachin S. Sule, W. Aronow
{"title":"Therapy of patients hospitalized for heart failure with abnormal versus normal left ventricular ejection fraction.","authors":"Sachin S. Sule, W. Aronow","doi":"10.1378/CHEST.136.4_MEETINGABSTRACTS.106S-A","DOIUrl":"https://doi.org/10.1378/CHEST.136.4_MEETINGABSTRACTS.106S-A","url":null,"abstract":"We investigated treatment of 200 consecutive patients hospitalized for heart failure (HF). Of the 200 patients, 100 (50%) had an abnormal left ventricular ejection fraction (LVEF) and 100 (50%) had a normal LVEF. Although in-hospital mortality was significantly increased in patients with HF and an abnormal LVEF, the duration of hospitalization and the NYHA class at discharge were similar in patients with HF and abnormal or normal LVEF.","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"35 1 1","pages":"50-4"},"PeriodicalIF":0.0,"publicationDate":"2009-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1378/CHEST.136.4_MEETINGABSTRACTS.106S-A","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66801731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hypersensitivity pneumonitis: evaluation and management.","authors":"Lisa Paul, Stuart G Lehrman, Wilbert S Aronow","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hypersensitivity pneumonitis consists of a group of diseases resulting from inhalation of organic particles causing an immunopathological reaction of the lungs in susceptible individuals. The diagnosis requires a detailed and careful history that would include social, environmental, and occupational status, pulmonary function tests, serum precipitins, bronchoalveolar lavage, imaging, and lung biopsy. Early recognition and avoidance of the causative agent is important although the use of corticosteroids hastens improvement of symptoms.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"35 3-4","pages":"177-87"},"PeriodicalIF":0.0,"publicationDate":"2009-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28621749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kaushang A Gandhi, Wilbert S Aronow, Majid Dudha, Stuart G Lehrman
{"title":"Hemoptysis in a patient with tracheopathia osteochondroplasia.","authors":"Kaushang A Gandhi, Wilbert S Aronow, Majid Dudha, Stuart G Lehrman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Tracheopathia osteochondroplasia is a rare slowly progressive benign disease of unknown etiology characterized by submucosal nodules protruding in the airway. Most patients are asymptomatic but with progression of disease, symptoms of cough, hemoptysis, dyspnea, wheezing, hoarseness, and rarely airway compromise have been reported. Management is symptomatic with control of cough, prophylaxis with antibiotics, and rarely surgery.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"35 3-4","pages":"196-8"},"PeriodicalIF":0.0,"publicationDate":"2009-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28621832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}