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The role of the mast cell and the use of sodium cromoglycate in the management of allergic disease. 肥大细胞的作用和氨基糖酸钠在变应性疾病治疗中的应用。
Clinical allergy Pub Date : 1980-07-01
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引用次数: 0
Double-blind trial comparing two dosage schedules of beclomethasone dipropionate aerosol with a placebo in the treatment of perennial rhinitis for twelve months. Brompton Hospital/medical research council collaborative trial. 双盲试验比较二丙酸倍氯米松气雾剂和安慰剂治疗多年性鼻炎12个月的两种剂量方案。布朗普顿医院/医学研究委员会合作试验。
Clinical allergy Pub Date : 1980-05-01
{"title":"Double-blind trial comparing two dosage schedules of beclomethasone dipropionate aerosol with a placebo in the treatment of perennial rhinitis for twelve months. Brompton Hospital/medical research council collaborative trial.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A double-blind trial comparing two dosage schedules of beclomethasone dipropinate, 200 micrograms 400 micrograms, with a placebo in the treatment of perennial rhinitis for 12 months has been undertaken in 108 patients. Both schedules of beclomethasone dipropionate were therapeutically effective but the improvement in both the nasal and conjunctival symptoms was more marked with the higher dosage. Clinical candidiasis was not observed on inspection of the nose in any of the patients before or during the trial and in only one patient was clinical candidiasis observed on inspection of the throat. Epistaxes occurred in twelve of forty patients allocated to beclomethasone dipropionate and four of twenty-three allocated to placebo who had not had them before the trial. Most of the episodes were minor but four patients, all on beclomethasone dipropionate, reduced the aerosol dosage because of epistaxes.</p>","PeriodicalId":75708,"journal":{"name":"Clinical allergy","volume":"10 3","pages":"239-51"},"PeriodicalIF":0.0,"publicationDate":"1980-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18045730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PGF2 alpha challenge test in asthma and chronic bronchitis. 哮喘和慢性支气管炎患者PGF2 α激发试验。
Clinical allergy Pub Date : 1980-03-01
J Parantainen, K Ritala, A Lahdensuo
{"title":"PGF2 alpha challenge test in asthma and chronic bronchitis.","authors":"J Parantainen,&nbsp;K Ritala,&nbsp;A Lahdensuo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>PGF2 alpha challenge tests were performed in twenty-three patients with bronchial and six patients with chronic bronchitis; two patients with allergic rhinitis and four healthy volunteers also participated in the trial. FEV1 measurements were used in assessing the reactions. PGF2 alpha challenge proved safe and practical in clinical use. A wide scattering in PGF2 alpha reactivity was seen, but sensitivity to PGF2 alpha did not correlate to several clinical criteria. Comparison with an ordinary histamine challenge revealed that the sensitivity of the patients to PGF2 alpha and histamine was not uniform.</p>","PeriodicalId":75708,"journal":{"name":"Clinical allergy","volume":"10 2","pages":"181-6"},"PeriodicalIF":0.0,"publicationDate":"1980-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18398433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Report of a meeting on allergic diseases. Geneva, 24-28 July 1978. 过敏性疾病会议报告。日内瓦，1978年7月24日至28日。
Clinical allergy Pub Date : 1980-01-01
{"title":"Report of a meeting on allergic diseases. Geneva, 24-28 July 1978.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75708,"journal":{"name":"Clinical allergy","volume":"10 1","pages":"1-20"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18374824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro differences between the lymphocytes of normal subjects and atopics. 正常人和特应性患者淋巴细胞的体外差异。
Clinical allergy Pub Date : 1979-11-01
O Strannegård, I L Strannegård
{"title":"In vitro differences between the lymphocytes of normal subjects and atopics.","authors":"O Strannegård,&nbsp;I L Strannegård","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recently evidence has accumulated that atopic disease is associated with a deficiency of thymus-derived (T) cells. This deficiency appears to be primary, rather than secondary to treatment or manifestations of the disease. Results of in vitro studies indicate that the deficiency is most pronounced in certain subpopulations of T cells, and therefore a disturbance of the balance between subsets of T cells, notably suppressor and helper T cells, may develop in vivo in atopics. Some results suggest that there is indeed a relative deficiency of suppressor T cells in atopic diseases, and thus the hyperproduction of IgE which is associated with these diseases may be explained. The cause of the T cell deficiency in atopy may be a basal cellular abnormality, manifested e.g. as increased sensitivity to inactivation by physiological substances, notably to agents which increase intracellular levels of cyclic AMP. It is equally possible that the T cell deficiency is a direct consequence of subnormal production of certain thymic hormones.</p>","PeriodicalId":75708,"journal":{"name":"Clinical allergy","volume":"9 6","pages":"637-43"},"PeriodicalIF":0.0,"publicationDate":"1979-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11445018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methods of quantifying circulating IgE. 循环IgE定量方法。
Clinical allergy Pub Date : 1979-11-01
P L Bruynzeel, L Berrens
{"title":"Methods of quantifying circulating IgE.","authors":"P L Bruynzeel,&nbsp;L Berrens","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75708,"journal":{"name":"Clinical allergy","volume":"9 6","pages":"605-6"},"PeriodicalIF":0.0,"publicationDate":"1979-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11723378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is mite hypersensitivity sex linked in children? 螨虫过敏与儿童的性别有关吗?
Clinical allergy Pub Date : 1979-09-01
G de Montis
{"title":"Is mite hypersensitivity sex linked in children?","authors":"G de Montis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75708,"journal":{"name":"Clinical allergy","volume":"9 5","pages":"543"},"PeriodicalIF":0.0,"publicationDate":"1979-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11701492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blood groups and reaginic hypersensitivity. 血型和皮肤过敏。
Clinical allergy Pub Date : 1979-09-01
G de Montis, M Balage, P Molkhou
{"title":"Blood groups and reaginic hypersensitivity.","authors":"G de Montis,&nbsp;M Balage,&nbsp;P Molkhou","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75708,"journal":{"name":"Clinical allergy","volume":"9 5","pages":"543-4"},"PeriodicalIF":0.0,"publicationDate":"1979-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11335702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacologic activity of histamine. 组胺的药理活性。
Clinical allergy Pub Date : 1979-03-01
L S Girsh
{"title":"Pharmacologic activity of histamine.","authors":"L S Girsh","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75708,"journal":{"name":"Clinical allergy","volume":"9 2","pages":"211-2"},"PeriodicalIF":0.0,"publicationDate":"1979-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11651785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum IgE in atopic dermatitis: relationship to severity of cutaneous involvement and course of disease as well as coexistence of atopic respiratory diseases. 特应性皮炎血清IgE:与皮肤受累程度、病程以及特应性呼吸系统疾病共存的关系
Clinical allergy Pub Date : 1978-05-01
B Wüthrich
{"title":"Serum IgE in atopic dermatitis: relationship to severity of cutaneous involvement and course of disease as well as coexistence of atopic respiratory diseases.","authors":"B Wüthrich","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serum IgE concentrations were determined according to the radioimmunosorbent technique (RIST, Phadebas) on 116 adult patients with atopic dermatitis of varying severity and activity. Geometric mean IgE levels of patients with atopic dermatitis were significantly higher compared with the mean level of ninety-three non-atopic adult subjects without parasitic infestation. Severity of the atopic dermatitis was highly correlated to the levels of serum IgE. Severe chronic cases with ever-recurrent exacerbations show the most extreme values. In the moderate forms of atopic dermatitis, coexistent bronchial asthma causes a greater increase in the IgE values. Among the mild or abortive forms higher IgE levels were found in cases with allergic rhinitis than in the cases with 'pure' atopic dermatitis. Other findings in connection with IgE in atopic dermatitis are summarized. The pathogenetic significance of IgE in the cutaneous changes is briefly discussed.</p>","PeriodicalId":75708,"journal":{"name":"Clinical allergy","volume":"8 3","pages":"241-8"},"PeriodicalIF":0.0,"publicationDate":"1978-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11869681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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