British journal of diseases of the chest最新文献_第5页

A short exercise and living course for ashtmatics 数学短练习与生活课程

British journal of diseases of the chest Pub Date : 1988-01-01 Epub Date: 2004-05-19 DOI: 10.1016/0007-0971(88)90036-8

M. Dean, E. Bell, C.R. Kershaw, B.M. Guyer, D.W. Hide

引用次数: 16

Bronchoalveolar lavage sampling of airway and alveolar cells 支气管肺泡灌洗取样气道和肺泡细胞

British journal of diseases of the chest Pub Date : 1988-01-01 Epub Date: 2004-05-19 DOI: 10.1016/0007-0971(88)90007-1

Bruce W.S. Robinson, Allan James, Alison H. Rose, Gregory F. Sterrett, Arthur W. Musk

{"title":"Bronchoalveolar lavage sampling of airway and alveolar cells","authors":"Bruce W.S. Robinson, Allan James, Alison H. Rose, Gregory F. Sterrett, Arthur W. Musk","doi":"10.1016/0007-0971(88)90007-1","DOIUrl":"10.1016/0007-0971(88)90007-1","url":null,"abstract":"<div><p>Bronchoalveolar lavage (BAL) cell counts are used to assess ‘alveolitis’ in patients with interstitial lung diseases (ILD) but inflammatory cells from airways can contribute to the differential cell count. To determine what BAL volume samples airway cells in patients with ILD we measured the proportion of bronchial epithelial cells (BECs) in four successive 25 ml aliquots in a single lung subsegment in 23 patients with ILD (cryptogenic fibrosing alveolitis (CFA) four, rheumatoid lung (RL) three, asbestosis (ASB) 11, sarcoidosis (SARC) five). Cells recovered from the first two 25 ml lavages exhibited higher proportions of BECs (15±14% and 9±2% respectively) than those from the rermaining two aliquots (3±1%, 3±1%, each <em>P</em><0.01), suggesting that the first 50 ml BAL preferentially sampled airway cells compared to the second 50 ml BAL. To evaluate airway and alveolar inflammatory cell proportions in ILD we performed two separate 50 ml BALs (samples I and II) in a single subsegment in 38 patients with ILD (CFA seven, RL five, ASB 19, SARC seven) and measured the proportions of recovered cells in each sample separately and combined. Seven control individuals were also studied. Sample I contained 1–67% (mean 26±3%) of the total recovered cells. Neutrophil (PMN) proportions were higher in sample I compared to sample II in CFA (20±6 vs 8±2%), RL (30±9 vs 8±2%) and ASB (12±2 vs 7±1%), <em>P</em><0.05 for each, but were similar in samples I and II in patients with SARC (3±1 vs 2±1%) and controls (2±1 vs 2±1%). In combined samples (I+II), absolute PMN proportions were up to 8% higher than in sample II alone whereas absolute lymphocyte proportions were up to 8% less than in sample II alone. These data suggest that separate processing of the fluid recovered from the first 50 ml BAL in ILD patients provides information on the location of inflammatory cells and improves the accuracy of BAL cell counts.</p></div>","PeriodicalId":75618,"journal":{"name":"British journal of diseases of the chest","volume":"82 ","pages":"Pages 45-55"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0007-0971(88)90007-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14296512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

Giant cell arteritis with pulmonary involvement 巨细胞动脉炎伴肺部受累

British journal of diseases of the chest Pub Date : 1988-01-01 Epub Date: 2004-05-19 DOI: 10.1016/0007-0971(88)90014-9

L. Doyle, L. McWilliam, P.S. Hasleton

引用次数: 31

Respiratory muscles and their neuromotor control (volume 26 of nuerology and neurobiology) 呼吸肌及其神经运动控制(神经病学和神经生物学第26卷)

British journal of diseases of the chest Pub Date : 1988-01-01 Epub Date: 2004-05-19 DOI: 10.1016/0007-0971(88)90055-1

S. Freedman

引用次数: 3

Cryptogenic bilateral fibrosing pleuritis 隐源性双侧纤维化性胸膜炎

British journal of diseases of the chest Pub Date : 1988-01-01 Epub Date: 2004-05-19 DOI: 10.1016/0007-0971(88)90042-3

D.R. Buchanan , I.D.A. Johnston , I.H. Kerr , M.R. Hetzel , B. Corrin , M. Turner-Warwick

{"title":"Cryptogenic bilateral fibrosing pleuritis","authors":"D.R. Buchanan , I.D.A. Johnston , I.H. Kerr , M.R. Hetzel , B. Corrin , M. Turner-Warwick","doi":"10.1016/0007-0971(88)90042-3","DOIUrl":"10.1016/0007-0971(88)90042-3","url":null,"abstract":"<div><p>We describe four patients with bilateral pleural effusions progressing to diffuse progressing to diffuse pleural thickening for which we have been unable to find any evidence of an infective, embolic or occupational aetiology. In order to avoid confusion with diffuse pleural thickening attributable to asbestos-related disease, the term cryptogenic bilateral fibrosing pleuritis is suggested.</p><p>The patients differed from those with pleural shadowing due to asbestos in that none of them gave a history of asbestos exposure, all were ill, presented with chest pain which was not always pleuritic in character, and had dyspnoea, cough or malaise. They had pleural effusions of variable size, pleural shadowing radiographically and raised sedimentation rates. Computed tomography revealed bilateral extensive pleural thickening in all cases. All four were HLA B44 positive.</p><p>Histology showed that in all cases the pleura was thickned by fibrous tissue. Both layers were affected and the pleural space was often obliterated. Otherwise the plaural surface was covered by organizing fibrin. Focal collections of lymphocytes were often present when the fibrous tissue abutted on the subpleural fat. No asbestos bodies were seen in any of the cases and in one patient electron microscopic fibre counts showed no excess of asbestos.</p><p>Pleural decortication was successful in three patients. In one of these, contralateral disease was successfully controlled with corticosteroids, but the fourth patient has not improved on corticosteroids.</p></div>","PeriodicalId":75618,"journal":{"name":"British journal of diseases of the chest","volume":"82 ","pages":"Pages 186-193"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0007-0971(88)90042-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14298070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 36

Diagnosis and management of respiratory diseases 呼吸系统疾病的诊断和管理

British journal of diseases of the chest Pub Date : 1988-01-01 Epub Date: 2004-05-19 DOI: 10.1016/0007-0971(88)90016-2

Nigel Bateman

引用次数: 2

Residua of Thoracic Trauma 胸部创伤残余

British journal of diseases of the chest Pub Date : 1988-01-01 Epub Date: 2004-05-19 DOI: 10.1016/0007-0971(88)90023-X

K.M. Pagliero

引用次数: 0

The effect of nifedipine on bronchial reactivity to inhaled histamine and methacholine: a comparative study in normal and asthmatic subjects 硝苯地平对吸入组胺和甲胆碱支气管反应性的影响:正常和哮喘受试者的比较研究

British journal of diseases of the chest Pub Date : 1988-01-01 Epub Date: 2004-05-19 DOI: 10.1016/0007-0971(88)90091-5

A.F. Henderson, J.F. Costello

{"title":"The effect of nifedipine on bronchial reactivity to inhaled histamine and methacholine: a comparative study in normal and asthmatic subjects","authors":"A.F. Henderson, J.F. Costello","doi":"10.1016/0007-0971(88)90091-5","DOIUrl":"10.1016/0007-0971(88)90091-5","url":null,"abstract":"<div><p>The effect of pretreatment with nifedipine 20 mg sublingually on the bronchoconstrictor response to inhaled histamine and methacholine in asthmatic and normal subjects has been studied. For each agonist the provocation concentration required to produce a 15% fall in FEV<sub>1</sub> (PC15) and a 35% fall in specific conductance (PC35) was determined. In the group of asthmatic subjects the responses to histamine were significantly attenuated by histamine, PC15 increasing from 0.29 mg/ml to 0.68 mg/ml (<em>P</em><0.001) and PC35 increasing from 0.25 mg/ml to 0.58 mg/ml (<em>P</em><0.001). Responses to methacholine showed less modification by nifedipine. PC15 increased from 0.23 mg/ml to 0.32 mg/ml (<em>P</em><0.05). Changes in PC35 were not significant. In the group of normal subjects no attenuation of the response to methacholine was produced by nifedipine but significant increases of PC15 (<em>P</em><0.002) and PC35 (<em>P</em><0.005) were produced by the agent. The results are consistent with nifedipine exerting an effect principally on mediators dependent on external calcium sources for stimulus-contraction coupling in the airways. The magnitude of change in the histamine response of the two groups was similar, suggesting calcium dependent mechanisms are not involved in asthmatic hyper-responsiveness.</p></div>","PeriodicalId":75618,"journal":{"name":"British journal of diseases of the chest","volume":"82 ","pages":"Pages 374-381"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0007-0971(88)90091-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14209468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Evaluation of directed coughing in cystic fibrosis 囊性纤维化患者定向咳嗽的评价

British journal of diseases of the chest Pub Date : 1988-01-01 Epub Date: 2004-05-19 DOI: 10.1016/0007-0971(88)90034-4

J. Bain , J. Bishop , A. Olinsky

引用次数: 34

The use of high dose inhaled beclomethasone dipropionate as a means of assessing steroid responsiveness in obstructive airways disease 使用大剂量吸入二丙酸倍氯米松作为评估阻塞性气道疾病中类固醇反应性的手段

British journal of diseases of the chest Pub Date : 1988-01-01 Epub Date: 2004-05-19 DOI: 10.1016/0007-0971(88)90038-1

A.G. Wardman, F.G. Simpson, A.J. Knox, R.L. Page, N.J. Cooke

引用次数: 18