Biomedical sciences instrumentation最新文献

UTILITY OF CHEST ULTRASONOGRAPHY IN QUANTIFYING CLOT AND PLEURAL EFFUSION VOLUME IN PRECLINICAL MODELS OF PLEURAL DISEASE. 胸部超声在胸膜疾病临床前模型中定量血凝块和胸腔积液量的应用。

Biomedical sciences instrumentation Pub Date : 2025-10-01

Christian J De Vera, Jincy Jacob, Sunil Christudas, Krishna Sarva, Elizabeth V Bailey, Andrey A Komissarov, Ali O Azghani, Steven Idell, Galina Florova

{"title":"UTILITY OF CHEST ULTRASONOGRAPHY IN QUANTIFYING CLOT AND PLEURAL EFFUSION VOLUME IN PRECLINICAL MODELS OF PLEURAL DISEASE.","authors":"Christian J De Vera, Jincy Jacob, Sunil Christudas, Krishna Sarva, Elizabeth V Bailey, Andrey A Komissarov, Ali O Azghani, Steven Idell, Galina Florova","doi":"","DOIUrl":"","url":null,"abstract":"Early detection and monitoring of pleural disease is critical in guiding appropriate treatment decisions. In the United States, chest radiography and computed tomography (CT) are the most employed imaging techniques to assess pleural disease for diagnosis and management. However, repeated imaging using these modalities exposes patients to cumulative ionizing radiation. In contrast, chest ultrasonography offers a safer, cost-effective, and portable alternative that could be of advantage to pediatric, rural, or resource-limited hospital settings. In addition, ultrasonography brings great utility to preclinical research where advanced imaging is limited. In this study, we developed and validated an ultrasound-based tool that enabled pleural effusion and clot volume quantification in our preclinical models of disease (early-stage empyema, advanced-stage empyema, and retained hemothorax). Four methods were tested for estimating pleural effusion and of the two of these most accurate methods were used to quantify clot volume. Across three animal models of pleural disease, both the Predicted Pleural Effusion and Clot Volume (mL) were closest to the actual volume (gold standard, mL) when area volumetry (pleural effusion or clot) was conducted in the coronal view of the pleural space of the subjects. Lastly, ultrasonographic imaging was able to distinguish the difference in clot dissolution (Predicted Clot Volume, mL) between subjects treated with vehicle control or fibrinolytic therapy, providing evidence of its utility in our preclinical model. These findings support the potential applications of these volumetric tools for preclinical and potential clinical use.","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"61 2","pages":"287-299"},"PeriodicalIF":0.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13148432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE ROLE OF PERIPHERAL VISION IN ENHANCING BALANCE AND POSTURAL STABILITY: INSIGHTS FROM CENTRAL VISION OBSTRUCTION. 周边视觉在增强平衡和姿势稳定性中的作用：来自中央视觉障碍的见解。

Biomedical sciences instrumentation Pub Date : 2025-04-01

Josephine Villicana, Adam Joseph, Olivia Goldstein, Kyle Luu, Elias Matta, Derrick Ngo, Kenneth Nakawaki, Kara Siebein, Rachel Sustek, Kristen Tang, Michael Shiraishi, Alex Mayorga, Seong Hyun Moon, Sivakumar Rajagopal, Raj Kumar Chauhan, Rahul Soangra

{"title":"THE ROLE OF PERIPHERAL VISION IN ENHANCING BALANCE AND POSTURAL STABILITY: INSIGHTS FROM CENTRAL VISION OBSTRUCTION.","authors":"Josephine Villicana, Adam Joseph, Olivia Goldstein, Kyle Luu, Elias Matta, Derrick Ngo, Kenneth Nakawaki, Kara Siebein, Rachel Sustek, Kristen Tang, Michael Shiraishi, Alex Mayorga, Seong Hyun Moon, Sivakumar Rajagopal, Raj Kumar Chauhan, Rahul Soangra","doi":"","DOIUrl":"","url":null,"abstract":"This study examines the role of peripheral vision in maintaining postural stability, particularly when central vision is obstructed, using Sensory Organization Testing (SOT) with computer dynamic posturography. Ten participants (5 males, 5 females, aged 21-34 years) were tested under three conditions: full vision, full occlusion, and central vision obstruction allowing only peripheral vision access. Results revealed significantly better balance performance in the peripheral vision condition during somatosensory perturbations (Condition 4), with equilibrium scores higher than in the full vision condition (p = 0.02). Similarly, visual preference (VIS) scores, indicating reliance on visual input, were significantly elevated under peripheral vision conditions (p = 0.03). These findings highlight peripheral vision's critical role in improving postural sway and maintaining balance when central vision is impaired, as seen in conditions such as age-related macular degeneration (AMD). While central vision is vital for daily tasks requiring focused attention, peripheral vision provides crucial environmental cues for balance and stability. This research underscores the need for targeted interventions and balance training programs to mitigate fall risks in individuals with central vision loss. Future studies will explore these effects in populations with visual impairments to enhance clinical relevance and applicability of central vision on balance.","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"61 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12211638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IMPACT OF NON-SKID SOCKS AND ANTERIOR WEIGHT ON POSTURAL RESPONSE AND STABILITY DURING PERTURBATION. 防滑袜和前部重量对摄动时姿势反应和稳定性的影响。

Biomedical sciences instrumentation Pub Date : 2025-04-01

Juaquin Acuna, Briana Kiphen, Alexander Lee, Amanda MacKinnon, Liz Manese, Austin Ngo, Nicole Oberhammer, Tommy Tran, Ethan Truong, Michael Shiraishi, Seong Hyun Moon, Sivakumar Rajagopal, Raj Kumar Chauhan, Rahul Soangra

{"title":"IMPACT OF NON-SKID SOCKS AND ANTERIOR WEIGHT ON POSTURAL RESPONSE AND STABILITY DURING PERTURBATION.","authors":"Juaquin Acuna, Briana Kiphen, Alexander Lee, Amanda MacKinnon, Liz Manese, Austin Ngo, Nicole Oberhammer, Tommy Tran, Ethan Truong, Michael Shiraishi, Seong Hyun Moon, Sivakumar Rajagopal, Raj Kumar Chauhan, Rahul Soangra","doi":"","DOIUrl":"","url":null,"abstract":"Non-skid socks and external weight are commonly utilized in healthcare and training to improve stability and simulate real-world conditions. However, their combined effects on postural response during perturbation remain unclear. This study examined how non-skid socks and added anterior weight affect latency and amplitude responses during postural perturbations. Ten healthy participants (mean age 24.5 ± 4.38 years) underwent randomized perturbation conditions with and without non-skid socks and 10% body weight applied via weighted vests. Results from two-way ANOVA and mixed-effects models revealed no significant effects of socks, weight, or their interaction on latency (p > 0.05). However, amplitude analysis showed a significant interaction (p < 0.001), indicating that the combination of socks and weight increased postural instability. Specifically, conditions involving non-skid socks and weight resulted in higher amplitudes, suggesting greater deviations of the center of gravity and increased fall risk. Conversely, non-skid socks alone reduced amplitude, enhancing stability compared to barefoot conditions. These findings highlight the nuanced effects of non-skid socks and added weight on balance and stability. While socks alone may improve postural control, their combination with weight appears to elevate instability. Future research should include larger, diverse samples to confirm these findings and guide clinical practice regarding non-skid socks and weighted training protocols.","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"61 1","pages":"16-22"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Roles of Echocardiography in Teaching of Cardiovascular Physiology at Pre-Clinical Level of Undergraduate Medical Education 超声心动图在医学本科临床前期心血管生理学教学中的作用

Biomedical sciences instrumentation Pub Date : 2023-09-06 DOI: 10.11648/j.bs.20230903.14

Suraj Adefabi Ogunyemi, Busayo Onafowoke Oguntola, O. Ogunlade

引用次数: 0

Impact of COVID-19 on Liver Function Tests Among Sudanese Patients: A Cross-Sectional Study of Khartoum State COVID-19对苏丹患者肝功能检测的影响:喀土穆州的横断面研究

Biomedical sciences instrumentation Pub Date : 2023-08-28 DOI: 10.11648/j.bs.20230903.12

Mogtaba Ahmed Mohammed, Alaa Abdalla Ibrahim, Ranya Adel Hamad, Jasim Mohamed Adam, Misson Shamsalfalah Ahmed, Musab Alsiddig Altayb, Mohammed Alhendi Ali, Amasi Abbas Idrees, Alaaeldeen Balal Ahmed

引用次数: 0

Positively Charged Water as a Tumor Growth Stimulator 带正电的水作为肿瘤生长刺激剂

Biomedical sciences instrumentation Pub Date : 2023-08-28 DOI: 10.11648/j.bs.20230903.13

Yuri Pivovarenko

引用次数: 0

Analysis of the Mechanism of Salvia miltiorrhiza in the Treatment of Pancreatic Cancer Based on Network Pharmacology 基于网络药理学的丹参治疗胰腺癌的作用机制分析

Biomedical sciences instrumentation Pub Date : 2023-07-27 DOI: 10.11648/j.bs.20230903.11

X. Tan, Jiajun Chen, Yuting Bai, Xin Chen

引用次数: 0

Serological Status of Viral Hepatitis B and Associated Factors Among Sex Workers in Douala (Littoral-Cameroon) 喀麦隆沿海地区杜阿拉性工作者乙型病毒性肝炎血清学状况及相关因素分析

Biomedical sciences instrumentation Pub Date : 2023-05-17 DOI: 10.11648/j.bs.20230902.13

Dikosso Claire Astrid, Voundi-Voundi Esther, Well a Well a Koul Pascal Blaise, Moubitang Matomba Christine, Ntchimou Tochie Juliana Vinciane, Mbiandjeu Tchoumke Marius, Romaric de Manfouo Tuono, Fotsing Kwetche Pierre Rene

引用次数: 0

Comparison of Pregnancy Outcomes in Thyroid Antibody-Positive Women with Different Fertilization Methods 甲状腺抗体阳性妇女不同受精方式妊娠结局的比较

Biomedical sciences instrumentation Pub Date : 2023-04-11 DOI: 10.11648/j.bs.20230902.11

Kang Yi-fan, Gao Qing-zhuo, Yin Zhao-fang, Wang Zhi-hong, Liang Hui-zhi, Yang Yuan, Yang Pan, Duan Xia

引用次数: 0

Serological Status of Hepatitis B Virus Among Pregnant Women in the Mifi District (West Cameroon) 喀麦隆西部Mifi地区孕妇乙型肝炎病毒血清学分析

Biomedical sciences instrumentation Pub Date : 2023-04-11 DOI: 10.11648/j.bs.20230902.12

Juliana Vinciane Ntchimou Tochie, Pascal Blaise Well a Well a Koul, Esther Voundi-Voundi, Claire Astrid Dikosso, Christine Moubitang Matomba, Marius Mbiandjeu Tchoumke, Romaric de Manfouo Tuono, Pierre Rene Fotsing Kwetche

引用次数: 0