Josephine Villicana, Adam Joseph, Olivia Goldstein, Kyle Luu, Elias Matta, Derrick Ngo, Kenneth Nakawaki, Kara Siebein, Rachel Sustek, Kristen Tang, Michael Shiraishi, Alex Mayorga, Seong Hyun Moon, Sivakumar Rajagopal, Raj Kumar Chauhan, Rahul Soangra
{"title":"THE ROLE OF PERIPHERAL VISION IN ENHANCING BALANCE AND POSTURAL STABILITY: INSIGHTS FROM CENTRAL VISION OBSTRUCTION.","authors":"Josephine Villicana, Adam Joseph, Olivia Goldstein, Kyle Luu, Elias Matta, Derrick Ngo, Kenneth Nakawaki, Kara Siebein, Rachel Sustek, Kristen Tang, Michael Shiraishi, Alex Mayorga, Seong Hyun Moon, Sivakumar Rajagopal, Raj Kumar Chauhan, Rahul Soangra","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study examines the role of peripheral vision in maintaining postural stability, particularly when central vision is obstructed, using Sensory Organization Testing (SOT) with computer dynamic posturography. Ten participants (5 males, 5 females, aged 21-34 years) were tested under three conditions: full vision, full occlusion, and central vision obstruction allowing only peripheral vision access. Results revealed significantly better balance performance in the peripheral vision condition during somatosensory perturbations (Condition 4), with equilibrium scores higher than in the full vision condition (p = 0.02). Similarly, visual preference (VIS) scores, indicating reliance on visual input, were significantly elevated under peripheral vision conditions (p = 0.03). These findings highlight peripheral vision's critical role in improving postural sway and maintaining balance when central vision is impaired, as seen in conditions such as age-related macular degeneration (AMD). While central vision is vital for daily tasks requiring focused attention, peripheral vision provides crucial environmental cues for balance and stability. This research underscores the need for targeted interventions and balance training programs to mitigate fall risks in individuals with central vision loss. Future studies will explore these effects in populations with visual impairments to enhance clinical relevance and applicability of central vision on balance.</p>","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"61 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12211638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juaquin Acuna, Briana Kiphen, Alexander Lee, Amanda MacKinnon, Liz Manese, Austin Ngo, Nicole Oberhammer, Tommy Tran, Ethan Truong, Michael Shiraishi, Seong Hyun Moon, Sivakumar Rajagopal, Raj Kumar Chauhan, Rahul Soangra
{"title":"IMPACT OF NON-SKID SOCKS AND ANTERIOR WEIGHT ON POSTURAL RESPONSE AND STABILITY DURING PERTURBATION.","authors":"Juaquin Acuna, Briana Kiphen, Alexander Lee, Amanda MacKinnon, Liz Manese, Austin Ngo, Nicole Oberhammer, Tommy Tran, Ethan Truong, Michael Shiraishi, Seong Hyun Moon, Sivakumar Rajagopal, Raj Kumar Chauhan, Rahul Soangra","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Non-skid socks and external weight are commonly utilized in healthcare and training to improve stability and simulate real-world conditions. However, their combined effects on postural response during perturbation remain unclear. This study examined how non-skid socks and added anterior weight affect latency and amplitude responses during postural perturbations. Ten healthy participants (mean age 24.5 ± 4.38 years) underwent randomized perturbation conditions with and without non-skid socks and 10% body weight applied via weighted vests. Results from two-way ANOVA and mixed-effects models revealed no significant effects of socks, weight, or their interaction on latency (p > 0.05). However, amplitude analysis showed a significant interaction (p < 0.001), indicating that the combination of socks and weight increased postural instability. Specifically, conditions involving non-skid socks and weight resulted in higher amplitudes, suggesting greater deviations of the center of gravity and increased fall risk. Conversely, non-skid socks alone reduced amplitude, enhancing stability compared to barefoot conditions. These findings highlight the nuanced effects of non-skid socks and added weight on balance and stability. While socks alone may improve postural control, their combination with weight appears to elevate instability. Future research should include larger, diverse samples to confirm these findings and guide clinical practice regarding non-skid socks and weighted training protocols.</p>","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"61 1","pages":"16-22"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suraj Adefabi Ogunyemi, Busayo Onafowoke Oguntola, O. Ogunlade
{"title":"The Roles of Echocardiography in Teaching of Cardiovascular Physiology at Pre-Clinical Level of Undergraduate Medical Education","authors":"Suraj Adefabi Ogunyemi, Busayo Onafowoke Oguntola, O. Ogunlade","doi":"10.11648/j.bs.20230903.14","DOIUrl":"https://doi.org/10.11648/j.bs.20230903.14","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73965943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mogtaba Ahmed Mohammed, Alaa Abdalla Ibrahim, Ranya Adel Hamad, Jasim Mohamed Adam, Misson Shamsalfalah Ahmed, Musab Alsiddig Altayb, Mohammed Alhendi Ali, Amasi Abbas Idrees, Alaaeldeen Balal Ahmed
{"title":"Impact of COVID-19 on Liver Function Tests Among Sudanese Patients: A Cross-Sectional Study of Khartoum State","authors":"Mogtaba Ahmed Mohammed, Alaa Abdalla Ibrahim, Ranya Adel Hamad, Jasim Mohamed Adam, Misson Shamsalfalah Ahmed, Musab Alsiddig Altayb, Mohammed Alhendi Ali, Amasi Abbas Idrees, Alaaeldeen Balal Ahmed","doi":"10.11648/j.bs.20230903.12","DOIUrl":"https://doi.org/10.11648/j.bs.20230903.12","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74670322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Positively Charged Water as a Tumor Growth Stimulator","authors":"Yuri Pivovarenko","doi":"10.11648/j.bs.20230903.13","DOIUrl":"https://doi.org/10.11648/j.bs.20230903.13","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73779306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of the Mechanism of <i>Salvia miltiorrhiza</i> in the Treatment of Pancreatic Cancer Based on Network Pharmacology","authors":"X. Tan, Jiajun Chen, Yuting Bai, Xin Chen","doi":"10.11648/j.bs.20230903.11","DOIUrl":"https://doi.org/10.11648/j.bs.20230903.11","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87423778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dikosso Claire Astrid, Voundi-Voundi Esther, Well a Well a Koul Pascal Blaise, Moubitang Matomba Christine, Ntchimou Tochie Juliana Vinciane, Mbiandjeu Tchoumke Marius, Romaric de Manfouo Tuono, Fotsing Kwetche Pierre Rene
{"title":"Serological Status of Viral Hepatitis B and Associated Factors Among Sex Workers in Douala (Littoral-Cameroon)","authors":"Dikosso Claire Astrid, Voundi-Voundi Esther, Well a Well a Koul Pascal Blaise, Moubitang Matomba Christine, Ntchimou Tochie Juliana Vinciane, Mbiandjeu Tchoumke Marius, Romaric de Manfouo Tuono, Fotsing Kwetche Pierre Rene","doi":"10.11648/j.bs.20230902.13","DOIUrl":"https://doi.org/10.11648/j.bs.20230902.13","url":null,"abstract":"Serological Status of Viral Hepatitis B and Associated Factors Among Sex Workers in Douala (Littoral-Cameroon","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"29 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88898667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kang Yi-fan, Gao Qing-zhuo, Yin Zhao-fang, Wang Zhi-hong, Liang Hui-zhi, Yang Yuan, Yang Pan, Duan Xia
{"title":"Comparison of Pregnancy Outcomes in Thyroid Antibody-Positive Women with Different Fertilization Methods","authors":"Kang Yi-fan, Gao Qing-zhuo, Yin Zhao-fang, Wang Zhi-hong, Liang Hui-zhi, Yang Yuan, Yang Pan, Duan Xia","doi":"10.11648/j.bs.20230902.11","DOIUrl":"https://doi.org/10.11648/j.bs.20230902.11","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88511912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juliana Vinciane Ntchimou Tochie, Pascal Blaise Well a Well a Koul, Esther Voundi-Voundi, Claire Astrid Dikosso, Christine Moubitang Matomba, Marius Mbiandjeu Tchoumke, Romaric de Manfouo Tuono, Pierre Rene Fotsing Kwetche
{"title":"Serological Status of Hepatitis B Virus Among Pregnant Women in the Mifi District (West Cameroon)","authors":"Juliana Vinciane Ntchimou Tochie, Pascal Blaise Well a Well a Koul, Esther Voundi-Voundi, Claire Astrid Dikosso, Christine Moubitang Matomba, Marius Mbiandjeu Tchoumke, Romaric de Manfouo Tuono, Pierre Rene Fotsing Kwetche","doi":"10.11648/j.bs.20230902.12","DOIUrl":"https://doi.org/10.11648/j.bs.20230902.12","url":null,"abstract":"","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"104 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80868889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zongxin Li, Yihan Xiao, Yuanhai Zhou, Ting Tang, Ping Yang, Long Sun, Xiuji Cui
{"title":"Hepatitis B Virus A1762T/G1764A Mutation Has a Minor Effect on the Viral Spliced DNA Expression","authors":"Zongxin Li, Yihan Xiao, Yuanhai Zhou, Ting Tang, Ping Yang, Long Sun, Xiuji Cui","doi":"10.11648/j.bs.20230901.15","DOIUrl":"https://doi.org/10.11648/j.bs.20230901.15","url":null,"abstract":": Background: Hepatitis B virus (HBV) is the major cause of chronic hepatitis B, which can lead to liver cirrhosis and hepatocellular carcinoma. During HBV replication, splicing of viral RNA frequently occurs, and the spliced RNA or DNA has been reported to be related to the development of liver disease. HBV transcription is mainly regulated by core promoter ranging from nucleotide 1613 to 1849 and the A1762T/G1764A mutation, which can increase the viral transcription, is frequently detected in this region. Objective: The study aimed to analyze the effect of the A1762T/G1764A mutation in the core promoter of HBV on viral RNA splicing. Methods: The wild type (WT) and the A1762T/G1764A mutant HBV genome were cloned into the pCDNA3.1 vector, which was then transiently transfected into HepG2 cells. The intracellular HBV DNA and core protein were determined by the Southern blot and the Western blot, respectively. The relative level of HBSD was examined by quantitative PCR using TB green reagent. Results: the A1762T/G1764A mutation could enhance the ability of viral replication, however, had a minor effect on HBSD expression. Conclusion: The double mutation in CP could regulate the viral transcription, but was not involved in the viral RNA splicing.","PeriodicalId":75599,"journal":{"name":"Biomedical sciences instrumentation","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90980728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}