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Bibliotheca haematologica最新文献

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Resealed red blood cells as a new blood transfusion product. 再密封红细胞作为一种新的输血产品。
Bibliotheca haematologica Pub Date : 1985-01-01 DOI: 10.1159/000410231
C Ropars, M Chassaigne, M C Villereal, G Avenard, C Hurel, C Nicolau
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引用次数: 23
Incorporation of allosteric effectors of hemoglobin in red blood cells. Physiological effects. 血红蛋白在红细胞中的变构效应。生理的影响。
Bibliotheca haematologica Pub Date : 1985-01-01 DOI: 10.1159/000410232
C Nicolau, B P Teisseire, C Ropars, M O Vallez, R A Herigault
{"title":"Incorporation of allosteric effectors of hemoglobin in red blood cells. Physiological effects.","authors":"C Nicolau, B P Teisseire, C Ropars, M O Vallez, R A Herigault","doi":"10.1159/000410232","DOIUrl":"https://doi.org/10.1159/000410232","url":null,"abstract":"","PeriodicalId":75590,"journal":{"name":"Bibliotheca haematologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000410232","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15118234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Encapsulation and targeting of drugs in electrically hemolysed red cells. 电溶血红细胞中药物的包封和靶向。
Bibliotheca haematologica Pub Date : 1985-01-01 DOI: 10.1159/000410234
K P Mishra, M C Patel, R D Ganatra, B B Singh
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引用次数: 1
Erythrocyte encapsulated thiosulfate sulfurtransferase. 红细胞包封硫代硫酸盐硫转移酶。
Bibliotheca haematologica Pub Date : 1985-01-01 DOI: 10.1159/000410230
J L Way, P Leung, L Ray, C Sander
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引用次数: 14
Entrapment of DNA and fluorescent compounds in erythrocyte carriers by endocytosis. 内吞作用在红细胞载体中捕获DNA和荧光化合物。
Bibliotheca haematologica Pub Date : 1985-01-01 DOI: 10.1159/000410235
M G Ihler
{"title":"Entrapment of DNA and fluorescent compounds in erythrocyte carriers by endocytosis.","authors":"M G Ihler","doi":"10.1159/000410235","DOIUrl":"https://doi.org/10.1159/000410235","url":null,"abstract":"","PeriodicalId":75590,"journal":{"name":"Bibliotheca haematologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000410235","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15118222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Comparison and potential of hypo-osmotic and iso-osmotic erythrocyte ghosts and carrier erythrocytes as drug and enzyme carriers. 低渗透和等渗透红细胞鬼和载体红细胞作为药物和酶载体的比较和潜力。
Bibliotheca haematologica Pub Date : 1985-01-01 DOI: 10.1159/000410223
R A Chalmers
{"title":"Comparison and potential of hypo-osmotic and iso-osmotic erythrocyte ghosts and carrier erythrocytes as drug and enzyme carriers.","authors":"R A Chalmers","doi":"10.1159/000410223","DOIUrl":"https://doi.org/10.1159/000410223","url":null,"abstract":"<p><p>Preparation, characteristics and properties of the three types of erythrocyte ghost are compared. These include light scattering properties, morphology, retention of cellular components and biochemical function including membrane transport. In vivo studies in the BALB/c mouse and Beagle dog have allowed the potential to be assessed of these erythrocyte ghosts as drug and enzyme cellular carriers in the treatment of human diseases. The development of the carrier erythrocyte with restored cellular ATP content and properties, including in vivo survival, that are closely similar to those of the normal erythrocyte is also described and its potential discussed.</p>","PeriodicalId":75590,"journal":{"name":"Bibliotheca haematologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000410223","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15118225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
G6PD encapsulation and metabolic properties of loaded erythrocytes. 负载红细胞的G6PD包封和代谢特性。
Bibliotheca haematologica Pub Date : 1985-01-01 DOI: 10.1159/000410228
G Fiorelli, T Ploner, W Berardi, C Manoussakis
{"title":"G6PD encapsulation and metabolic properties of loaded erythrocytes.","authors":"G Fiorelli,&nbsp;T Ploner,&nbsp;W Berardi,&nbsp;C Manoussakis","doi":"10.1159/000410228","DOIUrl":"https://doi.org/10.1159/000410228","url":null,"abstract":"<p><p>Two different dialysis methods were used to G6PD load the erythrocytes of G6PD deficient subjects. With both methods the yield of entrapment was about 30-40% of the added G6PD. The functional behaviour of these G6PD loaded erythrocytes was evaluated by HMS either in resting conditions or under oxidative stimulation. An increase of the metabolic activity of the G6PD loaded erythrocytes was found. This model provides an useful approach in studying the hemolytic activity of a variety of agents.</p>","PeriodicalId":75590,"journal":{"name":"Bibliotheca haematologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000410228","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15118231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Red cell-mediated microinjection of antibodies. 红细胞介导的抗体显微注射。
Bibliotheca haematologica Pub Date : 1985-01-01 DOI: 10.1159/000410236
R A Schlegel
{"title":"Red cell-mediated microinjection of antibodies.","authors":"R A Schlegel","doi":"10.1159/000410236","DOIUrl":"https://doi.org/10.1159/000410236","url":null,"abstract":"<p><p>Macromolecules can be introduced into cultured mammalian cells by fusing recipients with red cells, loaded by hypotonic hemolysis with the macromolecule of interest. This technique is called red cell-mediated microinjection. If recipient cells are in mitosis at the time of fusion, introduced macromolecules have access to nuclear components. When antibodies are introduced by this technique, they retain their specificity and are able to neutralize both cytoplasmic and nuclear molecules, thus providing a useful system for studying cellular functions within living cells.</p>","PeriodicalId":75590,"journal":{"name":"Bibliotheca haematologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000410236","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15118223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Entrapment of normal and mutant glucose 6-phosphate dehydrogenase (G6PD) within G6PD deficient erythrocytes. 正常和突变的葡萄糖6-磷酸脱氢酶(G6PD)在G6PD缺陷红细胞中的包埋。
Bibliotheca haematologica Pub Date : 1985-01-01 DOI: 10.1159/000410227
A De Flora, A Morelli, U Benatti
{"title":"Entrapment of normal and mutant glucose 6-phosphate dehydrogenase (G6PD) within G6PD deficient erythrocytes.","authors":"A De Flora,&nbsp;A Morelli,&nbsp;U Benatti","doi":"10.1159/000410227","DOIUrl":"https://doi.org/10.1159/000410227","url":null,"abstract":"<p><p>G6PD-deficient erythrocytes (Mediterranean type of this enzyme disorder) were loaded with a) normal G6PD purified to homogeneity from human erythrocytes, b) G6PD Mediterranean purified from deficient granulocytes. The first set of experiments led to complete normalization of biochemical properties of erythrocytes, as assessed by evaluating their metabolic competence under steady state conditions and under oxidative stress as well. The second type of experiment allowed us to conclude that mutant G6PD is not appreciably destroyed within the affected erythrocytes.</p>","PeriodicalId":75590,"journal":{"name":"Bibliotheca haematologica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000410227","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15118230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Red blood cells as carriers for drugs. A method for disseminating chemotherapeutics, hormones, enzymes and other therapeutic agents via the circulatory system. First International Conference on Red Blood Cell Carriers. Bellagio (Italy), February 27-March 2, 1984. 红细胞作为药物的载体。一种通过循环系统散布化疗药物、激素、酶和其他治疗剂的方法。第一届国际红血球载体会议。贝拉吉奥(意大利)，1984年2月27日至3月2日。
Bibliotheca haematologica Pub Date : 1985-01-01
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引用次数: 0
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