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Applied neurophysiology最新文献

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Introduction to Second International Symposium on Dorsal Root Entry Zone (DREZ) lesions. 第二届背根进入区(DREZ)病变国际研讨会简介。
Applied neurophysiology Pub Date : 1988-01-01 DOI: 10.1159/000099950
B S Nashold
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引用次数: 17
Investigation on cerebrospinal fluid opioids and neurotransmitters related to spinal cord stimulation. 脊髓刺激相关脑脊液阿片样物质和神经递质的研究。
Applied neurophysiology Pub Date : 1988-01-01 DOI: 10.1159/000099977
L Tonelli, T Setti, A Falasca, E Martignoni, E Torcia, F M Calcaterra, G A Merli, F Facchinetti
{"title":"Investigation on cerebrospinal fluid opioids and neurotransmitters related to spinal cord stimulation.","authors":"L Tonelli,&nbsp;T Setti,&nbsp;A Falasca,&nbsp;E Martignoni,&nbsp;E Torcia,&nbsp;F M Calcaterra,&nbsp;G A Merli,&nbsp;F Facchinetti","doi":"10.1159/000099977","DOIUrl":"https://doi.org/10.1159/000099977","url":null,"abstract":"<p><p>The purpose of this study was to assess the biochemical mechanisms underlying spinal cord stimulation (SCS). Seventeen patients with chronic pain were investigated by measuring cerebrospinal fluid concentrations of endogenous opioids and biogenic amines before and during dorsal column stimulation. Basal cerebrospinal fluid beta-endorphin levels were below the normal range. No significant change of norepinephrine, epinephrine, dopamine, beta-endorphin, beta-lipotropin, or adrenocorticotropic hormone levels were found after SCS. A 50% increase of cerebrospinal beta-endorphin and beta-lipotropin levels occurred in 6 out of 16 patients, namely those where SCS gave the major pain relief. These data confirm the derangement of the endogenous opioid system in chronic pain conditions and suggest that the beta-endorphin response to SCS could have clinical value in predicting the success of treatment.</p>","PeriodicalId":75525,"journal":{"name":"Applied neurophysiology","volume":"51 6","pages":"324-32"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000099977","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14038493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 42
Anatomic examination of human dorsal root entry zone lesions. 人背根进入区病变的解剖检查。
Applied neurophysiology Pub Date : 1988-01-01 DOI: 10.1159/000099967
R P Iacono, M L Aguirre, B S Nashold
{"title":"Anatomic examination of human dorsal root entry zone lesions.","authors":"R P Iacono,&nbsp;M L Aguirre,&nbsp;B S Nashold","doi":"10.1159/000099967","DOIUrl":"https://doi.org/10.1159/000099967","url":null,"abstract":"<p><p>The anatomic delineation of radiofrequency dorsal root entry zone lesions using the Nashold thermocouple electrode is presented. The sharply delineated lesions involve a major portion of the dorsal horn of the spinal cord including Rexed's lamina V and part of VI. The extent of these lesions is appropriate, based on the currently understood mechanisms of spinal generators of chronic deafferentation pain.</p>","PeriodicalId":75525,"journal":{"name":"Applied neurophysiology","volume":"51 2-5","pages":"225-9"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000099967","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14515251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
The Hopkins experience with lesions of the dorsal horn (Nashold's operation) for pain from avulsion of the brachial plexus. 霍普金斯对臂丛撕脱性疼痛的背角病变(纳什德手术)的经验。
Applied neurophysiology Pub Date : 1988-01-01 DOI: 10.1159/000099960
J N Campbell, C T Solomon, C S James
{"title":"The Hopkins experience with lesions of the dorsal horn (Nashold's operation) for pain from avulsion of the brachial plexus.","authors":"J N Campbell,&nbsp;C T Solomon,&nbsp;C S James","doi":"10.1159/000099960","DOIUrl":"https://doi.org/10.1159/000099960","url":null,"abstract":"<p><p>Lesions of the dorsal horn (DREZ operation) have been reported to be useful in reducing pain secondary to avulsion of the brachial plexus. Ten patients had the DREZ operation for this condition at The Johns Hopkins Hospital by one of us (JNC) between 1981 and 1985. Radiofrequency heat lesions were made. The patients were interviewed 7-52 months after the operation by one of two individuals not involved in the procedure to assess pain relief and postoperative complications. The mean pain relief was 85%, and there were no significant complications. It is concluded that the DREZ operation is the treatment of choice for treatment of severe pain that results from avulsion of the brachial plexus.</p>","PeriodicalId":75525,"journal":{"name":"Applied neurophysiology","volume":"51 2-5","pages":"170-4"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000099960","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14516172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 39
Experimental deafferentation syndromes. 实验性神经分离综合征。
Applied neurophysiology Pub Date : 1988-01-01 DOI: 10.1159/000099955
M Levitt
{"title":"Experimental deafferentation syndromes.","authors":"M Levitt","doi":"10.1159/000099955","DOIUrl":"https://doi.org/10.1159/000099955","url":null,"abstract":"<p><p>Animal models of dysesthesias have been established, and reveal the following major points. Dysesthesias of peripheral nerve or dorsal root origin have a central neural cause. Chronic dysesthesias of spinal origin have a cause which resides in the brain. The origins of these effects are lesions in the spinothalamic system. The causes of these effects are abnormal functionings among opiate, catecholamine, and purine pathways. Denervation supersensitivity is suggested.</p>","PeriodicalId":75525,"journal":{"name":"Applied neurophysiology","volume":"51 2-5","pages":"128-35"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000099955","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14417983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
As I saw it. 正如我所看到的。
Applied neurophysiology Pub Date : 1988-01-01 DOI: 10.1159/000099378
A E Walker
{"title":"As I saw it.","authors":"A E Walker","doi":"10.1159/000099378","DOIUrl":"https://doi.org/10.1159/000099378","url":null,"abstract":"","PeriodicalId":75525,"journal":{"name":"Applied neurophysiology","volume":"51 1","pages":"7-9"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000099378","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14417981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurosurgical technique of the dorsal root entry zone operation. 背根进入区手术的神经外科技术。
Applied neurophysiology Pub Date : 1988-01-01 DOI: 10.1159/000099956
B S Nashold
{"title":"Neurosurgical technique of the dorsal root entry zone operation.","authors":"B S Nashold","doi":"10.1159/000099956","DOIUrl":"https://doi.org/10.1159/000099956","url":null,"abstract":"<p><p>The dorsal root entry zone operation was introduced in 1976 to relieve the pain of brachial plexus avulsion. Since then it has been applied to pain treatment in paraplegia, postherpetic pain, phantom limb pain and other types of of deafferentation pain. Over 400 operations have been done at the Duke University Medical Center with overall good results in 60% of pain patients.</p>","PeriodicalId":75525,"journal":{"name":"Applied neurophysiology","volume":"51 2-5","pages":"136-45"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000099956","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14417984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 28
Confinia Neurologica/Applied Neurophysiology. 50 years. 应用神经生理学，50年。
Applied neurophysiology Pub Date : 1988-01-01
P L Gildenberg
{"title":"Confinia Neurologica/Applied Neurophysiology. 50 years.","authors":"P L Gildenberg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75525,"journal":{"name":"Applied neurophysiology","volume":"51 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14419829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary cultures of human caudate nucleus. 人尾状核的原代培养。
Applied neurophysiology Pub Date : 1988-01-01 DOI: 10.1159/000099379
V Silani, G Pezzoli, E Motti, A Falini, A Pizzuti, C Ferrante, A Zecchinelli, F Marossero, G Scarlato
{"title":"Primary cultures of human caudate nucleus.","authors":"V Silani,&nbsp;G Pezzoli,&nbsp;E Motti,&nbsp;A Falini,&nbsp;A Pizzuti,&nbsp;C Ferrante,&nbsp;A Zecchinelli,&nbsp;F Marossero,&nbsp;G Scarlato","doi":"10.1159/000099379","DOIUrl":"https://doi.org/10.1159/000099379","url":null,"abstract":"<p><p>It is possible to grow functional primary dissociated cultures and explants from stereotactic biopsies of human parkinsonian caudate nuclei. Two major classes of cells were identified on morphological grounds. The culture cells appear to be stimulated by an unidentified soluble factor(s) obtained from human fetal neuronal cells in vitro. Culture of primary neuronal and glial cells from human adult cerebral nuclei seems to be a useful tool for several research purposes and in particular for studying both trophic factor action and target effects on afferent neurons for prospective human brain grafting.</p>","PeriodicalId":75525,"journal":{"name":"Applied neurophysiology","volume":"51 1","pages":"10-20"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000099379","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14516167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Intraoperative electrical stimulation of the brain in patients with obsessive-compulsive neurosis. 强迫性神经症患者术中脑电刺激的研究。
Applied neurophysiology Pub Date : 1988-01-01 DOI: 10.1159/000099976
L V Laitinen, E Singounas
{"title":"Intraoperative electrical stimulation of the brain in patients with obsessive-compulsive neurosis.","authors":"L V Laitinen,&nbsp;E Singounas","doi":"10.1159/000099976","DOIUrl":"https://doi.org/10.1159/000099976","url":null,"abstract":"<p><p>Twenty patients with intractable obsessive-compulsive neurosis were operated under local anesthesia. Each patient had a lesion produced in 1 of the 4 brain targets: anterior internal capsule, rostral cingulum, middle cingulum, and genu of the corpus callosum. Before destructive permanent lesions were produced, the target area was stimulated electrically. Stimulation gave subjective or objective reactions in 30% of the patients: diminished anxiety, 3 patients; increased anxiety, 1 patient, and motor responses, 2 patients. None experienced an obsessive reaction to stimulation. The clinical effect of surgery was usually good.</p>","PeriodicalId":75525,"journal":{"name":"Applied neurophysiology","volume":"51 6","pages":"317-23"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000099976","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14180741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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