Advances in metabolic disorders最新文献

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The effects of neuropeptides on glucoregulation. 神经肽对血糖调节的作用。
Advances in metabolic disorders Pub Date : 1983-01-01 DOI: 10.1016/b978-0-12-027310-2.50022-0
A Iguchi, N Sakamoto, P D Burleson
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引用次数: 7
Positron emission tomographic studies of local cerebral glucose metabolism in humans in physiological and pathophysiological conditions. 人体在生理和病理生理条件下局部脑糖代谢的正电子发射断层扫描研究。
Advances in metabolic disorders Pub Date : 1983-01-01 DOI: 10.1016/b978-0-12-027310-2.50010-4
M Reivich, A Alavi
{"title":"Positron emission tomographic studies of local cerebral glucose metabolism in humans in physiological and pathophysiological conditions.","authors":"M Reivich, A Alavi","doi":"10.1016/b978-0-12-027310-2.50010-4","DOIUrl":"https://doi.org/10.1016/b978-0-12-027310-2.50010-4","url":null,"abstract":"","PeriodicalId":75445,"journal":{"name":"Advances in metabolic disorders","volume":"10 ","pages":"135-76"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17424322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 37
Coordinated responses of glucogenic hormones to central glucopenia: the role of the sympathoadrenal system. 糖原激素对中枢性血糖降低的协调反应:交感肾上腺系统的作用。
Advances in metabolic disorders Pub Date : 1983-01-01 DOI: 10.1016/b978-0-12-027310-2.50025-6
P E Cryer
{"title":"Coordinated responses of glucogenic hormones to central glucopenia: the role of the sympathoadrenal system.","authors":"P E Cryer","doi":"10.1016/b978-0-12-027310-2.50025-6","DOIUrl":"https://doi.org/10.1016/b978-0-12-027310-2.50025-6","url":null,"abstract":"<p><p>In normal humans glucagon plays a primary role in promoting glucose recovery from hypoglycemia, glucagon deficiency is largely compensated for by enhanced epinephrine secretion, and recovery from hypoglycemia fails to occur only in the absence of both glucagon and epinephrine. Defective glucose counterregulation is exemplified by patients with insulin-dependent diabetes. Although most such patients have deficient glucagon secretory responses to hypoglycemia, they counterregulate adequately because of intact epinephrine secretion. Some patients, however, become defenseless against hypoglycemia because of combined deficiencies of glucagon and epinephrine.</p>","PeriodicalId":75445,"journal":{"name":"Advances in metabolic disorders","volume":"10 ","pages":"469-83"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17425778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Insulin receptors in brain. 大脑中的胰岛素受体。
Advances in metabolic disorders Pub Date : 1983-01-01 DOI: 10.1016/b978-0-12-027310-2.50014-1
J Havrankova, J Roth, M J Brownstein
{"title":"Insulin receptors in brain.","authors":"J Havrankova,&nbsp;J Roth,&nbsp;M J Brownstein","doi":"10.1016/b978-0-12-027310-2.50014-1","DOIUrl":"https://doi.org/10.1016/b978-0-12-027310-2.50014-1","url":null,"abstract":"","PeriodicalId":75445,"journal":{"name":"Advances in metabolic disorders","volume":"10 ","pages":"259-68"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17721209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 30
The role of CCK-like peptides in appetite regulation. cck样肽在食欲调节中的作用。
Advances in metabolic disorders Pub Date : 1983-01-01 DOI: 10.1016/b978-0-12-027310-2.50023-2
R S Yalow, J Eng, E Straus
{"title":"The role of CCK-like peptides in appetite regulation.","authors":"R S Yalow,&nbsp;J Eng,&nbsp;E Straus","doi":"10.1016/b978-0-12-027310-2.50023-2","DOIUrl":"https://doi.org/10.1016/b978-0-12-027310-2.50023-2","url":null,"abstract":"<p><p>The physiological dose levels for the classically defined functions of CCK peptides, i.e., their effect on gall bladder contraction and release of pancreatic enzymes, are well established. However, the reported effects of peripheral administration of these peptides on regulation of satiety are achieved only at levels greatly in excess of the physiological range achieved in response to feeding. Thus, endogenous peripheral CCK alone would appear not to be the physiological satiety factor. The observations by Della-Fera et al. (1981) that lateral ventricular infusion into sheep of antibody to CCK results in increased feeding, if confirmed by other investigators and in other species, is the strongest evidence for a CSF-mediated role for CCK peptides in the regulation of satiety. However, numerous reports now delineate a variety of other CNS functions for these peptides. With so many effects reported, it is difficult at present to be certain which are real, which are direct or acting indirectly through another system, or which are the physiologically important functions. It can be expected that another decade will be required to sort out and define fully the multiple roles of CCK peptides that are synthesized independently in mucosal and in neuronal tissues.</p>","PeriodicalId":75445,"journal":{"name":"Advances in metabolic disorders","volume":"10 ","pages":"435-56"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17381770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Circumventricular organs: receptors and mediators of direct peptide hormone action on brain. 脑室周围器官:肽激素对大脑直接作用的受体和介质。
Advances in metabolic disorders Pub Date : 1983-01-01 DOI: 10.1016/b978-0-12-027310-2.50015-3
M Van Houten, B I Posner
{"title":"Circumventricular organs: receptors and mediators of direct peptide hormone action on brain.","authors":"M Van Houten,&nbsp;B I Posner","doi":"10.1016/b978-0-12-027310-2.50015-3","DOIUrl":"https://doi.org/10.1016/b978-0-12-027310-2.50015-3","url":null,"abstract":"<p><p>The concept of the brain as an endocrine target organ is not new, nor is it novel to consider the circumventricular organs as receptive regions of the brain for circulating substances. However, in this review we have emphasized the relatively novel concept that CVOs mediate exclusively the direct feedback actions of circulating peptide hormones on brain function. In addition we have presented speculations concerning the neural mechanisms by which signals arising from peptide hormone-receptor interaction might be relayed into the CNS, and indicated the possible involvement of CVO receptors in endocrine disorders. We hope that this analysis provides a conceptual framework for evaluating the functional relationship of circulating peptides to brain and inspires interest in this fascinating area of neuroendocrinology.</p>","PeriodicalId":75445,"journal":{"name":"Advances in metabolic disorders","volume":"10 ","pages":"269-89"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17381769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 66
CNS regulation of glucagon secretion. 中枢神经系统调节胰高血糖素分泌。
Advances in metabolic disorders Pub Date : 1983-01-01 DOI: 10.1016/b978-0-12-027310-2.50013-x
A B Steffens, J H Strubbe
{"title":"CNS regulation of glucagon secretion.","authors":"A B Steffens,&nbsp;J H Strubbe","doi":"10.1016/b978-0-12-027310-2.50013-x","DOIUrl":"https://doi.org/10.1016/b978-0-12-027310-2.50013-x","url":null,"abstract":"","PeriodicalId":75445,"journal":{"name":"Advances in metabolic disorders","volume":"10 ","pages":"221-57"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17424325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 26
Insulin in brain and other extrapancreatic tissues of vertebrates and nonvertebrates. 脊椎动物和非脊椎动物的脑和其他胰腺外组织中的胰岛素。
Advances in metabolic disorders Pub Date : 1983-01-01 DOI: 10.1016/b978-0-12-027310-2.50017-7
D Le Roith, S A Hendricks, M A Lesniak, S Rishi, K L Becker, J Havrankova, J L Rosenzweig, M J Brownstein, J Roth
{"title":"Insulin in brain and other extrapancreatic tissues of vertebrates and nonvertebrates.","authors":"D Le Roith,&nbsp;S A Hendricks,&nbsp;M A Lesniak,&nbsp;S Rishi,&nbsp;K L Becker,&nbsp;J Havrankova,&nbsp;J L Rosenzweig,&nbsp;M J Brownstein,&nbsp;J Roth","doi":"10.1016/b978-0-12-027310-2.50017-7","DOIUrl":"https://doi.org/10.1016/b978-0-12-027310-2.50017-7","url":null,"abstract":"","PeriodicalId":75445,"journal":{"name":"Advances in metabolic disorders","volume":"10 ","pages":"303-40"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17424327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 61
Insulin injected into CNS structures or into the carotid artery: effect on carbohydrate homeostasis of the intact animal. 胰岛素注射到中枢神经系统结构或颈动脉:对完整动物碳水化合物稳态的影响。
Advances in metabolic disorders Pub Date : 1983-01-01 DOI: 10.1016/b978-0-12-027310-2.50020-7
A J Szabo, O Szabo
{"title":"Insulin injected into CNS structures or into the carotid artery: effect on carbohydrate homeostasis of the intact animal.","authors":"A J Szabo,&nbsp;O Szabo","doi":"10.1016/b978-0-12-027310-2.50020-7","DOIUrl":"https://doi.org/10.1016/b978-0-12-027310-2.50020-7","url":null,"abstract":"<p><p>A synopsis is presented of studies (anatomical, immunohistological, immunochemical, and physiological) that suggested the presence of insulin receptors, native insulin, insulin-responsive cells, and insulin-sensitive glucoregulatory regions (centers) in the CNS. Evidence and consideration at variance with the above were also briefly listed. The controversies related to this new field of investigations are far from settled; they will provide a fertile field for exciting pioneering work for many investigators in the near future.</p>","PeriodicalId":75445,"journal":{"name":"Advances in metabolic disorders","volume":"10 ","pages":"385-400"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17425776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 28
Central nervous system regulation of insulin secretion. 中枢神经系统对胰岛素分泌的调节。
Advances in metabolic disorders Pub Date : 1983-01-01 DOI: 10.1016/b978-0-12-027310-2.50012-8
F Rohner-Jeanrenaud, E Bobbioni, E Ionescu, J F Sauter, B Jeanrenaud
{"title":"Central nervous system regulation of insulin secretion.","authors":"F Rohner-Jeanrenaud,&nbsp;E Bobbioni,&nbsp;E Ionescu,&nbsp;J F Sauter,&nbsp;B Jeanrenaud","doi":"10.1016/b978-0-12-027310-2.50012-8","DOIUrl":"https://doi.org/10.1016/b978-0-12-027310-2.50012-8","url":null,"abstract":"","PeriodicalId":75445,"journal":{"name":"Advances in metabolic disorders","volume":"10 ","pages":"193-220"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17424324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 66
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