Advances in internal medicine最新文献

{"title":"Author Guidelines JAIM","authors":"U. Shrestha","doi":"10.3126/jaim.v8i2.28582","DOIUrl":"https://doi.org/10.3126/jaim.v8i2.28582","url":null,"abstract":"Author Guidelines for the Journal of Advances in Internal Medicine.","PeriodicalId":75443,"journal":{"name":"Advances in internal medicine","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43767193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organophosphorous poisoning complicated with intermediate syndrome- A case report","authors":"H. Asraf, P. Ansari, K. Adhikari, S. Bista, J. Khirhari","doi":"10.3126/jaim.v8i2.28005","DOIUrl":"https://doi.org/10.3126/jaim.v8i2.28005","url":null,"abstract":"introduction according to a WHO stat approximately three million pesticide poisoning occurs worldwide and cause more than 40000 deaths per year.(1) newer review articles report that number of deaths and casualties attributed to organophosphate pesticide worldwide is about 300000.(2) Developing countries report alarming rates of toxicity and death. this is probably because of easy availability of highly toxic pesticides at the moment of stress.(3,4) Poisoning is a very common cause of medical admissions and deaths in nepalese hospitals.(5-12) Organophosphorus compounds are most common form of poisoning in nepal.(13-14)","PeriodicalId":75443,"journal":{"name":"Advances in internal medicine","volume":"8 1","pages":"33-34"},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3126/jaim.v8i2.28005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46220385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peripheral arterial disease.","authors":"W. Hiatt, M. Nehler","doi":"10.1007/0-387-22621-4_42","DOIUrl":"https://doi.org/10.1007/0-387-22621-4_42","url":null,"abstract":"","PeriodicalId":75443,"journal":{"name":"Advances in internal medicine","volume":"47 1","pages":"89-110"},"PeriodicalIF":0.0,"publicationDate":"2019-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/0-387-22621-4_42","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42511395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atrial fibrillation.","authors":"J. Kastor","doi":"10.1891/9780826194985.0041","DOIUrl":"https://doi.org/10.1891/9780826194985.0041","url":null,"abstract":"","PeriodicalId":75443,"journal":{"name":"Advances in internal medicine","volume":"41 1","pages":"365-97"},"PeriodicalIF":0.0,"publicationDate":"2019-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45738982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pancreatic Pseudocyst","authors":"Sophia L Fu","doi":"10.1002/9781119376293.ch100","DOIUrl":"https://doi.org/10.1002/9781119376293.ch100","url":null,"abstract":"","PeriodicalId":75443,"journal":{"name":"Advances in internal medicine","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/9781119376293.ch100","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50765731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lyme disease","authors":"James Lingard, A. Keeley, J. Douglas","doi":"10.1177/1755738019835244","DOIUrl":"https://doi.org/10.1177/1755738019835244","url":null,"abstract":"Lyme disease (LD) is the most common tick-borne infectious disease in the Northern hemisphere. LD can present with a wide range of symptoms depending on time since infection; from localised skin reactions such as erythema migrans, to widespread multi-system involvement. There may be non-specific symptoms of malaise, aching joints and muscles, and cognitive effects. Treatment with antibiotics is effective, especially if started in the early stages of infection. There is rising awareness of LD by the general public through media coverage and high-profile celebrity cases. Greater awareness has benefits, such as increased diagnosis and treatment of LD. However, cases in the media tend to highlight delays in diagnosis and complications of LD, which can lead to high levels of patient anxiety about the risks of LD.","PeriodicalId":75443,"journal":{"name":"Advances in internal medicine","volume":"12 1","pages":"304 - 309"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1755738019835244","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65524989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathogenesis and treatment of renal lithiasis; newer concepts.","authors":"Butt Aj","doi":"10.3126/JAIM.V7I1.19577","DOIUrl":"https://doi.org/10.3126/JAIM.V7I1.19577","url":null,"abstract":"Background and aim: Hypertension is a major risk factor for cardiovascular disease. Hypertension evolved as a major public problem in urban populations of many countries including Nepal, but little is known about its prevalence and risk factors in rural areas. The objective of our study was to assess the prevalence of and risk factors associated with hypertension.Methods: A community-based cross-sectional survey was carried out in November 2017 in a four days health camp where peoples from ward number eight of Suklagandaki municipality of Tanahu district were called for screening of diabetes mellitus. No prior notice was given to the population about screening of hypertension. We screened total of 568 participants. Demographics, anthropometry and two independent blood pressure (BP) readings were taken. The data was analyzed using descriptive and inferential statistics using SPSS version 18.0.Results: A total of 568 individuals were interviewed and taken complete BP, weight and height measurements. More than 1/3rd (36.26%) of the respondents were in age group 18- 39 years with mean age 47.49 ± 16.61. Nearly, 60% of the respondents were female. Whilst 17.3% were smokers and 20% reported drinking alcohol. Overall prevalence of hypertension was 41.55% and this was significantly associated with age, gender, education, size of family, smoking habits, intake of alcohol, presence of diabetes mellitus.Conclusion: The prevalence of hypertension was found to be high and it has become a important public health issue even in rural part of Nepal. Community screening program, timely detection, lifestyle modification, treatment and prevention are all important to deal","PeriodicalId":75443,"journal":{"name":"Advances in internal medicine","volume":"7 1","pages":"11-32"},"PeriodicalIF":0.0,"publicationDate":"2018-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3126/JAIM.V7I1.19577","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45224977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of fasting and postprandial hypertriglyceridemia and its association with carotid intima media thickness in Type II diabetes patients","authors":"R. Pathak, P. Adhikari, U. Pathak","doi":"10.3126/JAIM.V7I1.19578","DOIUrl":"https://doi.org/10.3126/JAIM.V7I1.19578","url":null,"abstract":"Background and aim: Type 2 diabetes mellitus is associated with the development of premature arteriosclerosis and a higher cardiovascular morbidity and mortality. Diabetic dyslipidaemia is believed to play an important role in the pathogenesis of accelerated atherosclerosis in this condition. B-mode ultrasound enables non-invasive, direct visualization of the arterial wall. The aim of this study was to correlate intima media thickness of the carotid artery (CIMT) quantification as a reliable marker of atherosclerotic burden in diabetes patients.Method: It was a Cross Sectional Study done on 50 patients in the age group of 30-70 years with type II Diabetes Mellitus of more than 5 years duration without hypertension. Carotid Intima Media Thickness (CIMT) was measured using an echotomographic system with a 7.5-MHz linear transducer probe. With the carotid bulb and the longitudinal projection of the common carotid artery 2cmx from carotid bulb, the site of the greatest thickness including a plaque lesion was sought along both near and far walls bilaterally.Results: The mean CIMT of subjects with fasting triglyceride level less than 150 mg/ dL was 13.2±0.48 mm with a range of 0.6-2.4 mm. Similarly the level between 150- 200 mg/dL was 1.89±0.54 mm with a range of 1.3-2.6 mm and level more than 200 mg/dL was 2.00±0.63 mm with a range of 0.8-2.6 mm. From the present study, it is clearly evident that age, duration of disease, fasting triglycerides and postprandial triglycerides have a significant impact on the CIMT, whereas other variables are having any significant impact on CIMT.Conclusion: The present study concludes both fasting and postprandial triglyceride levels correlate significantly with carotid intima media thickness. But, the correlation of postprandial triglyceride levels with carotid intima media thickness is better than that of fasting triglyceride levels with carotid intima media thickness, the postprandial hypertriglyceridemia despite normal fasting triglyceride level can be considered as an independent risk factor for atherosclerosis in type 2 diabetes mellitus.","PeriodicalId":75443,"journal":{"name":"Advances in internal medicine","volume":"7 1","pages":"17-22"},"PeriodicalIF":0.0,"publicationDate":"2018-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3126/JAIM.V7I1.19578","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41688387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late presentation of Ellis van Creveld Syndrome with Common atrium anomaly: A case report in a Nepalese Adult","authors":"A. Hirachan, K. Bishal, A. Maskey, Madhu Roka, G. Hirachan","doi":"10.3126/JAIM.V7I1.19580","DOIUrl":"https://doi.org/10.3126/JAIM.V7I1.19580","url":null,"abstract":"Ellis Van Creveld syndrome (EVC) is a rare genetic disorder having autosomal recessive inheritance characterized by chondrodystrophy, polydactyly, ectodermal dysplasia, and various cardiac anomalies. Acromelic shortening of upper and lower limbs, genu valgum, deformed teeth, short ribs and narrow thorax and other systemic anomalies complete the picture of this syndrome. The patients with the syndrome rarely survive into adulthood. Here, we report a 30 year old male with EVC presenting for the first time in middle age with Common atrium anomaly.","PeriodicalId":75443,"journal":{"name":"Advances in internal medicine","volume":"7 1","pages":"26-29"},"PeriodicalIF":0.0,"publicationDate":"2018-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3126/JAIM.V7I1.19580","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48323642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iron Deficiency Anemia: A profile of a tertiary care hospital","authors":"R. Joshi, D. Shrestha, D. Shah, S. Khadka","doi":"10.3126/jaim.v7i1.19575","DOIUrl":"https://doi.org/10.3126/jaim.v7i1.19575","url":null,"abstract":"Background and aim: Iron deficiency refers to the reduction of iron stores that precedes overt iron deficiency anemia. Iron deficiency anemia (IDA) is the commonest nutritional deficiency around the globe. Though etiology of IDA is multifaceted, and results from the iron demands which is not met by iron absorption in the body, regardless of the reason. This study was aimed to observe the several hematologic parameters among IDA cases presented to a tertiary level referral hospital of Nepal army.Methods: This prospective hospital based study was conducted among cases of iron deficiency anemia presented to a hematology clinic for six-month duration. With the help of semi-structured questionnaire demographic variables, presenting complaints, baseline laboratory parameters, iron profile and etiology of iron deficiency anemia were recorded. The collected data were entered in SPSS version 22 and analyzed.Results: In the six-month study period, there were 175 IDA cases who presented to hematology clinic. IDA was more common in females accounting 78% of 175 cases while rest were male. Mean value of parameters of iron profile were all significantly lower than normal range except TIBC which was significantly raised clinching the diagnosis of IDA. Weakness was the commonest mode of presentation (83, 47.4%). Poor intake was the main culprit of IDA (88, 50.3%). Most of the cases (82, 46.9%) belonged to moderate anemia group. Severity of anemia was associated with platelet count and total leucocyte count (p 0.05).Conclusion: In adult group, IDA is more common in women and non-specific symptoms like weakness is the commonest mode of presentation. Poor dietary intake is the main cause of IDA in our context. Among IDA cases, most of them belonged to moderate anemia.","PeriodicalId":75443,"journal":{"name":"Advances in internal medicine","volume":"7 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3126/jaim.v7i1.19575","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47069156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}