{"title":"Microscopic pathology of liver of capuchin monkey (Cebus albifrons) infected with Athesmia foxi (dicrocoelidae : trematoda) : a pictorial illustration.","authors":"V Kumar, W De Meurichy, L Van Peer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Histopathological changes in the livers of two white fronted capuchin monkeys, Cebus albifrons, associated with Athesmia foxi (Dicrocoelidae : Trematoda) infection are illustrated through photomicrographic plates. The lesions are confined in and around the hepatic biliary system. The bile ducts are greatly distended and thickened because of fibroblastic activity and collagen deposit in its walls. In one of the livers desquamative, necrotic and reorganizational changes are found to be well marked. At places the bile duct lumen contains infiltrating inflammatory cells and shed pieces of biliary epithelia mixed in a scanty necrotic tissue while elsewhere the necrotic changes are more pronounced and the bile duct contents are presented only by homogeneous amorphous debris. The overall picture is that of chronic cholangitis coupled with cholangiectasis.</p>","PeriodicalId":75428,"journal":{"name":"Acta zoologica et pathologica Antverpiensia","volume":" 75","pages":"71-7"},"PeriodicalIF":0.0,"publicationDate":"1980-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18269751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Glossina, domestic livestock and wild fauna: is a conciliation possible?].","authors":"J Gruvel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Animal trypanosomiasis is one of the major obstacles to livestock production in Africa. South of the Sahara. Tsetse fly control is considered to be the best method of overcoming the disease. The adverse effect of Glossina on cattle rearing and their role in the protection of the environment in West Africa is discussed. Meat production possibilities in infested areas, difficulties encountered in tsetse control and related problems are reviewed. Lastly solutions which would assure both livestock development and at the same time protection of the wildlife are examined.</p>","PeriodicalId":75428,"journal":{"name":"Acta zoologica et pathologica Antverpiensia","volume":" 75","pages":"29-48"},"PeriodicalIF":0.0,"publicationDate":"1980-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18210530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacterial systems for mutagenicity testing.","authors":"G R Mohn","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75428,"journal":{"name":"Acta zoologica et pathologica Antverpiensia","volume":" 75","pages":"133-48"},"PeriodicalIF":0.0,"publicationDate":"1980-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18067928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Legislation on the control and toxicity of chemical products].","authors":"M J Mercier","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Concern about the possible health and environmental hazards that may arise from exposure to an increasingly number of chemicals has resulted recently in new laws and regulations aimed at protecting human and its environment from an unreasonable risk. The Commission of the European Economic Community has recently passed legislation to control chemical substances. The essential prerequisites for safety evaluations of chemicals which are intended to be put on the market include the following background informations - physico-chemical properties - toxicological studies designed to evaluate human health effects - ecological studies designed to evaluate environmental fate - ecotoxicological studies designed to evaluate environmental effects.</p>","PeriodicalId":75428,"journal":{"name":"Acta zoologica et pathologica Antverpiensia","volume":" 75","pages":"99-115"},"PeriodicalIF":0.0,"publicationDate":"1980-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18269752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Estimation of the teratogenic effects of therapeutic drugs].","authors":"R Marsboom","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Therapeutics may induce embryological abnormalities in the laboratory animal, Now, it is known from experience that the currently applied experimental procedures allow to detect potential teratogenic risks in animals. There is only a slight possibility that a new therapeutic would be highly teratogenic as very special conditions are fundamental for the exteriorisation of the teratogenic effect, such as the sensibility and the developmental stage of the embryo, its genetic constitution and the physiology and pathology of the mother. The wellknown difficulties associated with the extrapolation of experimental results require that more species are used and that historical control data for each species and strains are kept allowing a global assessment of the results which better weighs the potential risk against the therapeutic activity of each new therapeutic.</p>","PeriodicalId":75428,"journal":{"name":"Acta zoologica et pathologica Antverpiensia","volume":" 75","pages":"165-73"},"PeriodicalIF":0.0,"publicationDate":"1980-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18269748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The choice of animals in toxicological screening: inbred strains and the factorial design of experiment.","authors":"M F Festing","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Most toxicological screening is currently carried out using genetically variable \"outbred\" stocks, though the Carcinogenesis Bioassay Programme run by the National Cancer Institute uses a single inbred or F1 hybrid strain of mice and rats. The use of several inbred of F1 hybrid strains in a factorial experiment design would have a number of advantages over either of the current designs. The factorial experiment would need to be no larger, and would therefore not be significantly more expensive, but it would be statistically and biologically more powerful. It should lead to fewer false positive and false negative results, and it offers improved methods of interpreting the results of their significance to man. Eventually, inbred strains will become as widely accepted in toxicology as they are at present in immunology.</p>","PeriodicalId":75428,"journal":{"name":"Acta zoologica et pathologica Antverpiensia","volume":" 75","pages":"117-31"},"PeriodicalIF":0.0,"publicationDate":"1980-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18269746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Comparative study of the chemical composition of excrement from some large African herbivorous mammals].","authors":"G Nibaruta, M Desiere, R Debaere","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the course of an ecological and comparative study concerning the beetle and fly communities inhabiting the droppings of some large African grass-eating mammals, we analysed the chemical composition of fresh dung dropped in winter 1977-1978 and in spring 1978. The mammals concerned are : Blesbok (Damaliscus pygargus albifrons Pallas), Impala (Aepyceros melampus Licht.), Bongo (Boocerus euryceros Ogilby), Nyala (Tragelaphus angasi Angas), Eland from Cap (Taurotragus oryx Pallas), Eland of Lloyd Derby (Taurotragus derbianus Gray) and Zebu (Bos indicus Lin). The results of these chemical analysis were treated by a statistical method based upon the different multivariate analysis, largely used in mathematical taxonomy. This method allowed to draw up dendrograms showing the affinities between the different types of excrements. The affinities stated appeared to be related to the systematic position of the species so far studied.</p>","PeriodicalId":75428,"journal":{"name":"Acta zoologica et pathologica Antverpiensia","volume":" 75","pages":"59-70"},"PeriodicalIF":0.0,"publicationDate":"1980-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18269750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Methods used for the in vivo study of the mutagenic properties of chemical substances].","authors":"A Leonard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Since man is much more closely related to other mammals than to bacteria fungi, plants or Drosophila, information obtained from mammals have obviously a much greater relevance to man than those from lower animals. Only the intact mammal can be utilized to obtain information on pharmacokinetic aspects such as absorption, elimination, biotransformation both inside and outside the target cells. Most mammalian assay systems employed for routine screening of mutagenic action rely on the detection of chromosome breaks in bone marrow, testis or in the dominant lethal test. In conclusion, it can be stated that in all cases, on should be guided by the consideration that no genetic risk whatsoever is acceptable when the mutagenic compound presents no clear benefit or when an alternative is available. Is this not the case, risks must be carefully balanced against possible benefits of the application of the mutagenic agent in question.</p>","PeriodicalId":75428,"journal":{"name":"Acta zoologica et pathologica Antverpiensia","volume":" 75","pages":"149-64"},"PeriodicalIF":0.0,"publicationDate":"1980-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18269747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of the urine of the okapi (Okapia johnstoni).","authors":"A R Glatston, S Smit","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The urine of six adult and two juvenile okapis housed in The Royal Rotterdam Zoological and Botanical Gardens were analysed qualitatively for the presence of protein, glucose, bilirubin, nitrite, blood and ketones and the pH was measured. Quantitative analyses were undertaken for osmolality, urea, creatinine and glucose. The results of the analyses were generally unremarkable with the exceptions of pH, glucose and in some cases the urea/creatinine ratios. However, with the exception of the glucose these other results are physiologically normal. One possible explanation for the presence of glucose in the urine of the okapis is dietary. In the wild these animals are folivorous and thus they may not be able to cope with the high level of sugar presented to them in their captive diet. However, it must be emphasised that this condition has no apparent ill effects on the animals which are in good health and are breeding successfully.</p>","PeriodicalId":75428,"journal":{"name":"Acta zoologica et pathologica Antverpiensia","volume":" 75","pages":"49-58"},"PeriodicalIF":0.0,"publicationDate":"1980-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18269749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The LOUVAIN rat and its importance in cancerology].","authors":"H Bazin, A Beckers, B Platteau, J P Kints","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The LOUVAIN rat model is characterized by a high incidence of spontaneous tumors which is extremely rare in animals. Presently, the spectrum of monoclonal immunoglobulins synthetized by these tumors is the largest ever discovered in animals. Particularly, the LOUVAIN rat tumors produced the only IgD and IgE monoclonal immunoglobuling discovered in an animal species up to now. The contributions of this model to experimental cancerology were multiple: some of them originate in its high incidence, its anatomopathological type or its production of homogenous proteins, others, in the antigenic properties of the monoclonal immunoglobulins synthetized by these tumors, allowing the study of their natural analogues in absolutely new experimental conditions.</p>","PeriodicalId":75428,"journal":{"name":"Acta zoologica et pathologica Antverpiensia","volume":" 72","pages":"35-44"},"PeriodicalIF":0.0,"publicationDate":"1979-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11700226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}