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Acta Universitatis Palackianae Olomucensis Facultatis Medicae最新文献

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Experiences with the therapy of the malignant diseases of the thyroid gland. 甲状腺恶性疾病的治疗体会。
Acta Universitatis Palackianae Olomucensis Facultatis Medicae Pub Date : 2000-01-01
R Kralik, J Knotek, R Seman, V Casnocha
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引用次数: 0
CDT transferrin level as an aspect in choice of immunosuppressants after kidney transplantation. CDT转铁蛋白水平作为肾移植后免疫抑制剂选择的一个方面。
Acta Universitatis Palackianae Olomucensis Facultatis Medicae Pub Date : 2000-01-01
M Hrabalová, T Grosmanová, P Bachleda
{"title":"CDT transferrin level as an aspect in choice of immunosuppressants after kidney transplantation.","authors":"M Hrabalová, T Grosmanová, P Bachleda","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75423,"journal":{"name":"Acta Universitatis Palackianae Olomucensis Facultatis Medicae","volume":"143 ","pages":"85-7"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21965016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemokine receptors. 趋化因子受体。
Acta Universitatis Palackianae Olomucensis Facultatis Medicae Pub Date : 2000-01-01 DOI: 10.5507/bp.2000.001
Agáta Gibejová
{"title":"Chemokine receptors.","authors":"Agáta Gibejová","doi":"10.5507/bp.2000.001","DOIUrl":"https://doi.org/10.5507/bp.2000.001","url":null,"abstract":"Chemokines mediate their multiple effects by binding to a variety of specific receptors, that comprise a subfamily of rhodopsin-like, 7-transmembrane domain receptors, coupled to G proteins. Some of these receptors serve as coreceptors for HIV, some of them could be expressed as markers for T lymphocyte functional differentiation. This review aims at summarising data on chemokine receptors, their function in vivo, their target cells and it also mentions association of chemokine receptor polymorphisms with human disease.","PeriodicalId":75423,"journal":{"name":"Acta Universitatis Palackianae Olomucensis Facultatis Medicae","volume":"143 1","pages":"9-18"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70742247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The results of liver surgery for malignant tumors. 肝脏恶性肿瘤手术的结果。
Acta Universitatis Palackianae Olomucensis Facultatis Medicae Pub Date : 2000-01-01
V Treska, T Skalický
{"title":"The results of liver surgery for malignant tumors.","authors":"V Treska, T Skalický","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75423,"journal":{"name":"Acta Universitatis Palackianae Olomucensis Facultatis Medicae","volume":"143 ","pages":"103-4"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21965063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concept of surgical oncology in the Czech Republic. 捷克共和国外科肿瘤学的概念。
Acta Universitatis Palackianae Olomucensis Facultatis Medicae Pub Date : 2000-01-01
J Zaloudík
{"title":"Concept of surgical oncology in the Czech Republic.","authors":"J Zaloudík","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75423,"journal":{"name":"Acta Universitatis Palackianae Olomucensis Facultatis Medicae","volume":"143 ","pages":"109"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21965069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgery therapy in cancer patients of the south Moravia with respect of their trends according to data processed by Czech Cancer Registry. 根据捷克癌症登记处处理的数据，南摩拉维亚癌症患者的手术治疗趋势。
Acta Universitatis Palackianae Olomucensis Facultatis Medicae Pub Date : 2000-01-01
V Kolcová, E Geryk, V Zácek, J Zaloudík, M Jechová
{"title":"Surgery therapy in cancer patients of the south Moravia with respect of their trends according to data processed by Czech Cancer Registry.","authors":"V Kolcová, E Geryk, V Zácek, J Zaloudík, M Jechová","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75423,"journal":{"name":"Acta Universitatis Palackianae Olomucensis Facultatis Medicae","volume":"143 ","pages":"90-1"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21966982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oncological problems associated with Barrett's oesophagus. 与巴雷特食管相关的肿瘤问题。
Acta Universitatis Palackianae Olomucensis Facultatis Medicae Pub Date : 2000-01-01
R Aujeský, C Neoral, V Král, J Klein
{"title":"Oncological problems associated with Barrett's oesophagus.","authors":"R Aujeský,&nbsp;C Neoral,&nbsp;V Král,&nbsp;J Klein","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Reflux oesophagitis does not represent only an isolated collection of symptoms affecting the patients' quality of life but the risk of serious complications including the benign stenosis and carcinoma of oesophagus, too. Barrett's oesophagus (BO) has the highest risk for development of the neoplasia due to reflux oesophagitis.</p>","PeriodicalId":75423,"journal":{"name":"Acta Universitatis Palackianae Olomucensis Facultatis Medicae","volume":"143 ","pages":"77"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21965007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extended lung resections after inductive chemotherapy. 诱导化疗后延长肺切除。
Acta Universitatis Palackianae Olomucensis Facultatis Medicae Pub Date : 2000-01-01
J Klein, V Král, C Neoral, V Kolek, T Bohanes, R Aujeský, M Herman
{"title":"Extended lung resections after inductive chemotherapy.","authors":"J Klein,&nbsp;V Král,&nbsp;C Neoral,&nbsp;V Kolek,&nbsp;T Bohanes,&nbsp;R Aujeský,&nbsp;M Herman","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75423,"journal":{"name":"Acta Universitatis Palackianae Olomucensis Facultatis Medicae","volume":"143 ","pages":"88-9"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21965019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemokine receptors. 趋化因子受体。
Acta Universitatis Palackianae Olomucensis Facultatis Medicae Pub Date : 2000-01-01
A Gibejová
{"title":"Chemokine receptors.","authors":"A Gibejová","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chemokines mediate their multiple effects by binding to a variety of specific receptors, that comprise a subfamily of rhodopsin-like, 7-transmembrane domain receptors, coupled to G proteins. Some of these receptors serve as coreceptors for HIV, some of them could be expressed as markers for T lymphocyte functional differentiation. This review aims at summarising data on chemokine receptors, their function in vivo, their target cells and it also mentions association of chemokine receptor polymorphisms with human disease.</p>","PeriodicalId":75423,"journal":{"name":"Acta Universitatis Palackianae Olomucensis Facultatis Medicae","volume":"143 ","pages":"9-18"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21966981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of colchicine and its derivatives on the expression of selected isoforms of cytochrome P450 in primary cultures of human hepatocytes. 秋水仙碱及其衍生物对人肝细胞原代培养细胞色素P450特定亚型表达的影响。
Acta Universitatis Palackianae Olomucensis Facultatis Medicae Pub Date : 2000-01-01
Z Dvorák, J Ulrichová, M Modrianský, P Maurel
{"title":"Effect of colchicine and its derivatives on the expression of selected isoforms of cytochrome P450 in primary cultures of human hepatocytes.","authors":"Z Dvorák,&nbsp;J Ulrichová,&nbsp;M Modrianský,&nbsp;P Maurel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The study addressed the effect of colchicine and its derivatives on the protein levels of cytochrome P450 (CYP) 1A2, 2A6, 3A4, 2C9/19, and 2E1 isoforms. Primary human hepatocyte culture was the model of choice. Levels of individual CYP isoforms were detected using immunoblotting. Colchicine caused an increase of CYP2E1 protein content, colchiceine and N-deacetylcolchiceine induced isoforms CYP2C9, 2E1 and 3A4 whereas colchicoside induced CYP2C9 and 2E1. The levels of CYP1A2 and 2A6 were unaffected by any of tested compounds. Demecolcine and 3-demethylcolchicine had no effect on any studied P450 isoform. Since colchicine is an exclusive substrate of CYP3A4 whereas it induces CYP2E1, there is a suspicion rather at protein stabilization than at gene induction concerning induction origin.</p>","PeriodicalId":75423,"journal":{"name":"Acta Universitatis Palackianae Olomucensis Facultatis Medicae","volume":"143 ","pages":"47-50"},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21965002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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