Acta paediatrica Scandinavica. Supplement最新文献_第8页

Growth hormone treatment in adults with growth hormone deficiency: effect on muscle fibre size and proportions. 生长激素缺乏症成人的生长激素治疗:对肌纤维大小和比例的影响。

Acta paediatrica Scandinavica. Supplement Pub Date : 1989-01-01 DOI: 10.1111/j.1651-2227.1989.tb11246.x

H M Whitehead, J S Gilliland, I V Allen, D R Hadden

引用次数: 34

Clinical experience with recombinant somatropin: German collaborative study. 重组生长激素的临床经验:德国合作研究。

Acta paediatrica Scandinavica. Supplement Pub Date : 1988-01-01

J R Bierich

引用次数: 0

Prediction of adult height: methods and problems. 成人身高预测:方法与问题。

Acta paediatrica Scandinavica. Supplement Pub Date : 1988-01-01

M A Preece

引用次数: 0

Surgical correction of short stature. 身材矮小的外科矫正

Acta paediatrica Scandinavica. Supplement Pub Date : 1988-01-01

G Trivella, R Aldegheri

引用次数: 0

Clinical relevance of serum measurements of insulin-like growth factors and somatomedin binding proteins. 胰岛素样生长因子和生长抑素结合蛋白血清测定的临床意义。

Acta paediatrica Scandinavica. Supplement Pub Date : 1988-01-01

M B Ranke, W F Blum, J R Bierich

引用次数: 0

Contemporary tools for the analysis of episodic growth hormone secretion and clearance in vivo. 用于分析体内偶发性生长激素分泌和清除的当代工具。

Acta paediatrica Scandinavica. Supplement Pub Date : 1988-01-01

J D Veldhuis, A Faria, M L Vance, W S Evans, M O Thorner, M L Johnson

{"title":"Contemporary tools for the analysis of episodic growth hormone secretion and clearance in vivo.","authors":"J D Veldhuis, A Faria, M L Vance, W S Evans, M O Thorner, M L Johnson","doi":"","DOIUrl":"","url":null,"abstract":"The evaluation of episodic GH release is made difficult by the apparently random nature of GH secretory bursts, the frequent occurrence of minimally detectable plasma GH concentrations, the relatively rapid plasma disappearance rate of endogenous GH, and the large number of metabolic and environmental cues that alter GH dynamics. Nonetheless, the development of objective, statistically based, and reproducible computerized algorithms to quantify episodic GH release has offered new insights into the pathophysiological regulation of GH secretion in health and disease. Moreover, the recent formulation of algebraically explicit biophysical models of GH secretion and clearance has made possible a complete quantitative description of GH secretory and clearance dynamics over a full 24 hours of observation. Such analytical tools allow investigators to enumerate with statistically bounded confidence limits the number, amplitude, durations, and temporal locations of all significant underlying secretory bursts and simultaneously calculate the half-life of endogenous GH disappearance from all GH concentrations and their variances considered together. Accordingly, in conjunction with contemporary refinements in GH assay techniques, such novel approaches to dissecting the temporal structure of GH secretion and clearance in vivo should result in significantly enhanced understanding of GH dynamics in health and disease.","PeriodicalId":75408,"journal":{"name":"Acta paediatrica Scandinavica. Supplement","volume":"347 ","pages":"63-82"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14208169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Growth and growth disorders. Proceedings of an international symposium. Paris, France, 6-7 November 1987. 生长和生长障碍。国际研讨会论文集。1987年11月6日至7日，法国巴黎。

Acta paediatrica Scandinavica. Supplement Pub Date : 1988-01-01

引用次数: 0

Urinary IGF-I measurement and its clinical application. 尿igf - 1测定及其临床应用。

Acta paediatrica Scandinavica. Supplement Pub Date : 1988-01-01

N Hizuka, K Takano, K Asakawa, I Sukegawa, R Horikawa, Y Yoshizawa, S Saito, K Shizume

{"title":"Urinary IGF-I measurement and its clinical application.","authors":"N Hizuka, K Takano, K Asakawa, I Sukegawa, R Horikawa, Y Yoshizawa, S Saito, K Shizume","doi":"","DOIUrl":"","url":null,"abstract":"Immunoreactive and receptor-reactive IGF-I was found to be present in human urine; 30% of the IGF-I immunoreactivity in urine was in its free form and the remainder was a high molecular weight form (approximately 40,000 MW). Urinary IGF-I was quantified by radioimmunoassay after extraction by Sep-Pak C18 cartridge, a method that measures only the free form of IGF-I. Daily (24-hour) urinary IGF-I excretion was measured in 3 hypopituitary children and 16 short normal children. The IGF-I level in the 24-hour urine samples correlated with the plasma IGF-I level and the mean 24-hour plasma GH concentration. The mean 24-hour plasma GH concentration, however, correlated better with the GH level in the 24-hour urine samples and the plasma IGF-I level than with the urinary IGF-I value. The mean IGF-I levels in single urine samples from normal subjects lay between those from patients with acromegaly (which were high) and those from patients with hypopituitarism (which were low). There were overlaps, however, in individual values between the normal and hypopituitary patients. These data indicate that urinary IGF-I values are altered by the GH secretion state, though the clinical application of urinary IGF-I measurement may be limited.","PeriodicalId":75408,"journal":{"name":"Acta paediatrica Scandinavica. Supplement","volume":"347 ","pages":"127-33"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14380900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Age, sex and growth hormone dependent changes in urinary IGF-I. 年龄、性别和生长激素依赖性尿igf - 1的变化。

Acta paediatrica Scandinavica. Supplement Pub Date : 1988-01-01

S Yokoya, S Suwa, H Maesaka, T Tanaka

引用次数: 0

Cow's milk allergy in the first year of life. An Italian Collaborative Study. 一岁后对牛奶过敏。一项意大利合作研究。

Acta paediatrica Scandinavica. Supplement Pub Date : 1988-01-01

{"title":"Cow's milk allergy in the first year of life. An Italian Collaborative Study.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"The diagnosis of Cow's Milk Protein Allergy was considered in 303 infants aged less than 1 year, who presented with one or more of the following symptoms: acute reaction related to cow's milk proteins (CMP) ingestion, severe colics, persisting vomiting, protracted diarrhea with or without blood and mucus, failure to thrive, eczema, respiratory symptoms, such as chronic rhinitis and wheezing. A diagnosis of CMPA was confirmed in 148 cases (60%): 125 relapsed on milk challenge, 23 were not challenged because of acute reactions at onset, presence of specific IgE (RAST and prick), and improvement on milk free diet. Familial atopy, familial history of CMPA and previous acute gastroenteritis were significantly more frequent in cases than in 191 age matched controls. Breast feeding was not more common or of longer duration in controls, compared to cases. Mean IgE serum levels were higher (46.3 U/ml) in cases than in controls (17 U/ml), while specific Cow's Milk Protein IgE were found in 71/148 cases (48%). 15 infants entered the study while on breast milk, because of the confirmed relation between their symptoms and CMP on the maternal diet. These infants had a higher prevalence of IgE mediated problems. All cases improved on a milk free diet but in 26 (17.8%) a further modification of the diet was required after the first prescription. Milk challenge was monitored by simple laboratory tests: all cases who had symptoms on challenge showed at least one test modification. Six infants, with no history of acute reaction, showed severe self-limited clinical symptoms at challenge. Key words: cow's milk allergy, milk, allergy, prick test, eczema, diarrhea.","PeriodicalId":75408,"journal":{"name":"Acta paediatrica Scandinavica. Supplement","volume":"348 ","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14202727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0