R L Goldenberg, C A Hickey, S P Cliver, S Gotlieb, T W Woolley, H J Hoffman
{"title":"Abbreviated scale for the assessment of psychosocial status in pregnancy: development and evaluation.","authors":"R L Goldenberg, C A Hickey, S P Cliver, S Gotlieb, T W Woolley, H J Hoffman","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Data from five existing psychosocial scales were used to develop an abbreviated scale for the assessment of psychosocial status during pregnancy.</p><p><strong>Methods: </strong>Scales were self-administered by 842 black and 381 white low-income multiparous women at risk for poor pregnancy outcome. Trait anxiety (Speilberger), self-esteem (Rosenberg), mastery (Pearlin), and depression (CES-D) were assessed at 24-26 weeks' gestation; subjective stress (Schar) was assessed at 30-32 weeks' gestation. The 59 pooled items were examined for redundancy and the discernment of primary factors using principal factor analysis. Regression analysis was used to determine if the resulting abbreviated scale (28 items) would provide information similar to that obtained with the 59 item pool (full scale) in predicting gestational age (GA), birth weight (BW), fetal growth restriction (FGR), and preterm delivery (PTD).</p><p><strong>Results: </strong>The abbreviated scale was highly correlated (r = 0.97) with the 59-item pool and the six factors isolated were generally compatible with the major characteristics assessed by the five original scales. The distribution of FGR and PTD by scale quartile was similar for the abbreviated and the combined scales. Logistic regression analysis of scores for all women revealed that poor (high) scores on both the full (p = 0.0151) and the abbreviated scales (p = 0.0131) were positively associated with FGR, but not with PTD. In linear regression analysis poor (high) scores on both the full (p = 0.0024) and the abbreviated scale (p = 0.0019) were negatively related to BW, but not to GA. When data for black and white women were examined separately, the two scales provided comparable information.</p><p><strong>Conclusions: </strong>The abbreviated psychosocial scale provided information similar to that obtained with 59 pooled items in predicting GA, BW, FGR, and PTD.</p>","PeriodicalId":75400,"journal":{"name":"Acta obstetricia et gynecologica Scandinavica. Supplement","volume":"165 ","pages":"19-29"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20164310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L S Bakketeig, H J Hoffman, G Jacobsen, J A Hagen, B E Storvik
{"title":"Intrauterine growth pattern by the tendency to repeat small-for-gestational-age births in successive pregnancies.","authors":"L S Bakketeig, H J Hoffman, G Jacobsen, J A Hagen, B E Storvik","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Fetuses of women who repeat small-for-gestational-age births in successive pregnancies may have a different intrauterine growth pattern than SGA birth of non-repeater mothers. Also repeated SGA births may grow differently depending on whether the tendency to repeat is due to some external factors such as cigarette smoking (\"false repeaters\") or due to genetic or intrinsic factors (\"true repeaters\").</p><p><strong>Material and methods: </strong>Fetal growth were compared in a \"nested case-control\" study within a longitudinal (cohort) study, comparing three types of SGA births, 23 of \"true repeater\" mothers, 46 of \"false repeater\" mothers and 65 of non-repeater mothers, and these were compared with 1017 non-SGA births. Fetal growth was compared using a regression analysis based on repeated measurements (four for each woman).</p><p><strong>Results: </strong>For mean abdominal diameter the \"true repeater\" SGA births grew more slowly towards the end of pregnancy. However, the growth curves show only minor differences between the three types of SGA births, but the patterns are grossly different from the growth of non-SGA births (controls).</p><p><strong>Conclusion: </strong>The intrauterine growth retardation starts early in pregnancy, and is not strikingly different between births of repeater and non-repeater mothers.</p>","PeriodicalId":75400,"journal":{"name":"Acta obstetricia et gynecologica Scandinavica. Supplement","volume":"165 ","pages":"3-7"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20164460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"XV FIGO World Congress of Gynecology and Obstetrics. Copenhagen, Denmark, 3-8 August 1997. Abstracts. Part 4.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75400,"journal":{"name":"Acta obstetricia et gynecologica Scandinavica. Supplement","volume":"167 Pt 4 ","pages":"1-103"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20227782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"XV FIGO World Congress of Gynecology and Obstetrics. Copenhagen, Denmark, 3-8 August 1997. Abstracts. Part 5.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75400,"journal":{"name":"Acta obstetricia et gynecologica Scandinavica. Supplement","volume":"167 Pt 5 ","pages":"1-96"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20227783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The possible use of antiprogestins for contraception.","authors":"M Bygdeman, K G Danielsson, M L Swahn","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>A number of compounds, antiprogestins, e.g. mifepristone, onapristone and lilopristone, have been developed which compete with progesterone at the receptor level. One of these, mifepristone, is in combination with a prostaglandin analogue currently in use for termination of early pregnancy. The possibility to use these compounds for contraceptive purposes is presently under evaluation.</p><p><strong>Methods: </strong>The possible contraceptive effect of antiprogestins has been evaluated in both clinical and experimental studies.</p><p><strong>Results: </strong>Administration of antiprogestin during the follicular phase has an inhibitory effect on follicular development and ovulation, and on endometrial development and function if administered during the secretory phase of the menstrual cycle. A high dose of mifepristone, 200 mg, administered immediately following ovulation is highly effective in preventing implantation, most likely due to an effect on endometrial receptivity. It seems that the endometrium is more sensitive to antiprogestin than is the ovulatory process. Low weekly, 2.5 mg to 5 mg, and daily doses, 0.5 mg, of mifepristone did not inhibit ovulation, but a significant effect on endometrial development and especially endometrial function judged from measurement of the expression of a number of markers for endometrial receptivity could be demonstrated.</p><p><strong>Conclusion: </strong>The effect of mifepristone on the endometrium may be sufficient to prevent implantation, and if so, an oral contraceptive method could be developed which has no effect on ovarian function.</p>","PeriodicalId":75400,"journal":{"name":"Acta obstetricia et gynecologica Scandinavica. Supplement","volume":"164 ","pages":"75-7"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20170654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Can pre-eclampsia be predicted and prevented?","authors":"R Erkkola","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Pre-eclampsia is still a condition which worldwide kills many mothers and is the cause of a great number of perinatal deaths and one of the leading causes of perinatal morbidity even in developed countries. The definition of pre-eclampsia still varies in the literature, thus making the comparison of results difficult and the issue obscure. Nevertheless, recent advances in research into the pathophysiology of pre-eclampsia has greatly enhanced our understanding of his condition. Therefore, new strategies to predict and prevent this disorder are sought for and emerging.</p>","PeriodicalId":75400,"journal":{"name":"Acta obstetricia et gynecologica Scandinavica. Supplement","volume":"164 ","pages":"98-100"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20170037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Gardner, Robert L. Goldenberg, Cliver Sp, L. Boots, Hoffman Hj
{"title":"Maternal serum concentrations of human placental lactogen, estradiol and pregnancy specific beta 1-glycoprotein and fetal growth retardation.","authors":"M. Gardner, Robert L. Goldenberg, Cliver Sp, L. Boots, Hoffman Hj","doi":"10.1016/0002-9378(95)90801-3","DOIUrl":"https://doi.org/10.1016/0002-9378(95)90801-3","url":null,"abstract":"","PeriodicalId":75400,"journal":{"name":"Acta obstetricia et gynecologica Scandinavica. Supplement","volume":"165 1","pages":"56-8"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0002-9378(95)90801-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53259146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Birth weight of relatives by maternal tendency to repeat small-for-gestational-age (SGA) births in successive pregnancies.","authors":"P Magnus, L S Bakketeig, H Hoffman","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background and method: </strong>Small-for-gestational-age (SGA) infants represent a heterogeneous group of normal and growth-retarded children. To assess the familial aggregation of reduced fetal growth, birth weights in both maternal and paternal relatives of 1246 index children in the Scandinavian SGA Study were compared across groups defined by the SGA outcome of the index child as well as that of earlier siblings.</p><p><strong>Results: </strong>Mean maternal birth weight +/- SEM was 3127 +/- 54 g for mothers who had experienced two SGA births as opposed to 3424 +/- 22 for mothers with no SGA births. Mean paternal birth weight was 3497 +/- 88 g and 3665 +/- 24 in the same two groups. The odds ratio (with 95% confidence interval) for having a mother with birth weight below the 10th percentile was 1.74 (0.85-3.58) for the group where two SGA births had occurred compared to no SGA births and it was 2.49 (1.22-5.07) for having a father with birth weight below the 10th percentile. There was no correlation between maternal and paternal birth weights.</p><p><strong>Conclusions: </strong>The association also to paternal birth weight suggests the presence of genetic or common environmental factors in explaining the tendency to have SGA children. Although taking parental birth weights into consideration will aid in diagnosing growth-retardation in a SGA child, SGA remains a heterogeneous group where familial and non-familial cases will be difficult to separate.</p>","PeriodicalId":75400,"journal":{"name":"Acta obstetricia et gynecologica Scandinavica. Supplement","volume":"165 ","pages":"35-8"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20164312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Obstetric interventions and perinatal asphyxia in growth retarded term infants.","authors":"J Langhoff-Roos, G Lindmark","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The monitoring of fetal growth during pregnancy is usually justified because of the increased perinatal risk of these babies.</p><p><strong>Methods: </strong>In 1552 infants from the Scandinavian Small for Gestational Age Study the need for obstetric interventions, risk of fetal asphyxia and immediate neonatal outcome at term have been studied in relation to different types of fetal growth retardation, including sub-groups with low ponderal index or low amount of subcutaneous fat.</p><p><strong>Results: </strong>The need for obstetric intervention indicated by suspected fetal asphyxia before or during labor was increased 3-fold (6-8%) for growth retarded infants both in SGA infants in general and infants with asymmetric body proportions. The immediate perinatal outcome, however, was favorable with Apgar below 8 at 5 min in only 2% irrespective of the type of growth retardation, in spite of the fact that less than 25% of the SGA pregnancies and 10% of those with asymmetric fetal growth had been eligible for close antenatal fetal monitoring.</p><p><strong>Conclusion: </strong>With a moderate increase in interventions at delivery, perinatal outcome was highly favorable for term infants with a weight for gestational age, weight for length or skinfold for weight below the 10th percentile in this population of Scandinavian parous mothers.</p>","PeriodicalId":75400,"journal":{"name":"Acta obstetricia et gynecologica Scandinavica. Supplement","volume":"165 ","pages":"39-43"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20164314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}