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Acta neuropathologica. Supplementum最新文献

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Immunohistochemical demonstration of viral antigens in paraffin embedded autopsy specimens of virally infected central nervous system. 病毒感染中枢神经系统尸体石蜡包埋标本中病毒抗原的免疫组织化学证实。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_41
J Löhler
{"title":"Immunohistochemical demonstration of viral antigens in paraffin embedded autopsy specimens of virally infected central nervous system.","authors":"J Löhler","doi":"10.1007/978-3-642-81553-9_41","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_41","url":null,"abstract":"<p><p>Viral antigens are preserved in routinely processed and paraffin embedded CNS tissue to an extent that they can be traced by the highly sensitive and specific unlabeled antibody method. Using this method, it was possible to visualize antigens of measles, influenza A, polio, varicella-zoster, herpes simplex, cytomegalo, parainfluenza I, lymphocytic choriomeningitis, Moloney, and Friend virus.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"139-41"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18059815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Endothelial surface charge: blood-brain barrier opening to horseradish peroxidase induced by the polycation protamin sulfate. 内皮表面电荷:血脑屏障向多阳离子硫酸维生素诱导的辣根过氧化物酶开放。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_2
Z Nagy, H Peters, I Hüttner
{"title":"Endothelial surface charge: blood-brain barrier opening to horseradish peroxidase induced by the polycation protamin sulfate.","authors":"Z Nagy,&nbsp;H Peters,&nbsp;I Hüttner","doi":"10.1007/978-3-642-81553-9_2","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_2","url":null,"abstract":"<p><p>Perfusion of rat brain with the polycation protamin sulfate caused a decrease in the stainability of luminal surface of cerebral endothelium to positively charged colloidal iron. This change reflecting a decrease in the anionic sites of the endothelial plasma membrane was accompanied by opening of the blood-brain barrier to horseradish peroxidase. The polyanion heparin reversed colloidal iron binding but failed to prevent permeability alteration of the cerebral endothelium.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"7-9"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17986108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 44
Uncommon oligodendrogliomas. 罕见的少突胶质瘤。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_29
J Escalona-Zapata
{"title":"Uncommon oligodendrogliomas.","authors":"J Escalona-Zapata","doi":"10.1007/978-3-642-81553-9_29","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_29","url":null,"abstract":"","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"94-6"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17988503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Sträussler's disease. Straussler的疾病。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01
F Seitelberger
{"title":"Sträussler's disease.","authors":"F Seitelberger","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"341-3"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histopathological findings in adrenoleukodystrophy autopsy report of a boy aged 11 years and 11 months. 11岁11个月男孩肾上腺脑白质营养不良的尸检报告。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_64
R Schnabel, C Gerhard
{"title":"Histopathological findings in adrenoleukodystrophy autopsy report of a boy aged 11 years and 11 months.","authors":"R Schnabel,&nbsp;C Gerhard","doi":"10.1007/978-3-642-81553-9_64","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_64","url":null,"abstract":"<p><p>Clinical and pathohistological findings of a boy who died of adrenoleukodystrophy at the age of 11 years and 11 months are reported. Special features are the advanced diffuse demyelination of cerebral and cerebellar white matter as well as the \"burnt-out\" stage of myelin breakdown with fibrous gliosis. The leukodystrophic process is accompanied by secondary loss of axons with marked atrophy of grey matter in the whole of the brain stem, dentates and cerebellar cortex of the Purkinje cell type. The degeneration of nerve fibres is considered as a complex mechanism, which is not restricted to the Wallerian type. -- Only free cholesterol was shown by histochemical tests in the preserved myelin sheaths. Free and esterified cholesterol was found in the adrenal cortical cells. The lack of detectable cholesteryl esters in the sparse sudanophilic macrophages was unexpected. This finding may be attributed to the sensitivity of the histochemical method or to interference by achromogenic 7-ketocholesterol.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"215-8"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Ultrastructural variability of demyelinating lesions in experimental allergic encephalomyelitis and multiple sclerosis. 实验性过敏性脑脊髓炎和多发性硬化症脱髓鞘病变的超微结构变异性。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_52
H Lassmann, K Kitz, H M Wisniewski
{"title":"Ultrastructural variability of demyelinating lesions in experimental allergic encephalomyelitis and multiple sclerosis.","authors":"H Lassmann,&nbsp;K Kitz,&nbsp;H M Wisniewski","doi":"10.1007/978-3-642-81553-9_52","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_52","url":null,"abstract":"","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"173-5"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Tissue alterations induced by radio- and chemotherapy in brain with malignant gliomas. 脑恶性胶质瘤放化疗所致的组织改变。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_33
D Schiffer, R Soffietti, M T Giordana, L Tarenzi
{"title":"Tissue alterations induced by radio- and chemotherapy in brain with malignant gliomas.","authors":"D Schiffer,&nbsp;R Soffietti,&nbsp;M T Giordana,&nbsp;L Tarenzi","doi":"10.1007/978-3-642-81553-9_33","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_33","url":null,"abstract":"<p><p>35 brains with malignant gliomas treated by surgery, radiotherapy and chemotherapy and processed by means of the \"complete study\" technique have been studied. The preliminary results are reported. Many types of changes have been observed. Areas of coagulative necrosis with vessel alterations and teleangectasias are present around the tumor in many cases. Different pathologic aspects are observed distant from the tumor. Edema both in the homo - and contralateral hemisphere is constantly present. Severe edema with demyelination, axon disappearance and loss of cells is frequently found associated with prolonged survival. Often it is accompanied by wide or small areas filled with macrophages. Spongio-necrosis in the white matter of contralateral temporal lobe has been observed in two cases and telangiectasias areas have been found in another one. The relation between changes and treatment is discussed.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"109-10"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Morphological diagnosis of Niemann-Pick disease type C by skin and conjunctival biopsies. 皮肤及结膜活检对C型尼曼-匹克病的形态学诊断。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_61
M L Arsénio-Nunes, F Goutières
{"title":"Morphological diagnosis of Niemann-Pick disease type C by skin and conjunctival biopsies.","authors":"M L Arsénio-Nunes,&nbsp;F Goutières","doi":"10.1007/978-3-642-81553-9_61","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_61","url":null,"abstract":"<p><p>Skin and conjunctival biopsies were performed in six children with mental deterioration, incoordination, involuntary movements and discrete visceromegaly. Two main types of inclusions were observed: 1) intracytoplasmic bodies containing membranous profiles loosely disposed in concentric or parallel arrays, lying in clear cells of eccrine sweat glands, hair follicles and cells of the basal layer of skin and 2) pleomorphous membrane bound bodies with a multivesicular aspect which are formed by vacuoles, stacks of lamellae and amorphous electron dense material. Subsequent biochemical studies showing a slight increase of sphingomyelin in liver and normal sphingomyelinase in leukocytes supported the morphological diagnosis of Niemann-Pick disease type C. The qualitative regional diversity of storage is stressed and the interest of both skin and conjunctival biopsies in the diagnosis of this affection is discussed.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"204-7"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17323455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Neuropathology of primary generalized epilepsies with awakening grand mal. 原发性全身性癫痫伴觉醒大发作的神经病理学。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_108
H J Meencke, D Janz, J Cervos-Navarro
{"title":"Neuropathology of primary generalized epilepsies with awakening grand mal.","authors":"H J Meencke,&nbsp;D Janz,&nbsp;J Cervos-Navarro","doi":"10.1007/978-3-642-81553-9_108","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_108","url":null,"abstract":"","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"378-80"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17836590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Melanosis cerebelli. 脑黑变病。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_114
C Bianchi, G Grandi, N Berti, L Di Bonito
{"title":"Melanosis cerebelli.","authors":"C Bianchi,&nbsp;G Grandi,&nbsp;N Berti,&nbsp;L Di Bonito","doi":"10.1007/978-3-642-81553-9_114","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_114","url":null,"abstract":"<p><p>Melanosis cerebelli (melanic pigmentation involving the dentate nuclei and the granular layer of the cerebellar cortex) is described in three patients, aged between 72 and 99 years. In two cases atrophic changes of the Alzheimer type co-existed in the cerebral cortex. One patient had a history of tremors, possibly cerebellar in origin.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"400-2"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17986100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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