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Acta neuropathologica. Supplementum最新文献

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Immunohistochemical demonstration of viral antigens in paraffin embedded autopsy specimens of virally infected central nervous system. 病毒感染中枢神经系统尸体石蜡包埋标本中病毒抗原的免疫组织化学证实。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_41
J Löhler
{"title":"Immunohistochemical demonstration of viral antigens in paraffin embedded autopsy specimens of virally infected central nervous system.","authors":"J Löhler","doi":"10.1007/978-3-642-81553-9_41","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_41","url":null,"abstract":"<p><p>Viral antigens are preserved in routinely processed and paraffin embedded CNS tissue to an extent that they can be traced by the highly sensitive and specific unlabeled antibody method. Using this method, it was possible to visualize antigens of measles, influenza A, polio, varicella-zoster, herpes simplex, cytomegalo, parainfluenza I, lymphocytic choriomeningitis, Moloney, and Friend virus.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"139-41"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18059815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Endothelial surface charge: blood-brain barrier opening to horseradish peroxidase induced by the polycation protamin sulfate. 内皮表面电荷:血脑屏障向多阳离子硫酸维生素诱导的辣根过氧化物酶开放。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_2
Z Nagy, H Peters, I Hüttner
{"title":"Endothelial surface charge: blood-brain barrier opening to horseradish peroxidase induced by the polycation protamin sulfate.","authors":"Z Nagy,&nbsp;H Peters,&nbsp;I Hüttner","doi":"10.1007/978-3-642-81553-9_2","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_2","url":null,"abstract":"<p><p>Perfusion of rat brain with the polycation protamin sulfate caused a decrease in the stainability of luminal surface of cerebral endothelium to positively charged colloidal iron. This change reflecting a decrease in the anionic sites of the endothelial plasma membrane was accompanied by opening of the blood-brain barrier to horseradish peroxidase. The polyanion heparin reversed colloidal iron binding but failed to prevent permeability alteration of the cerebral endothelium.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"7-9"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17986108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 44
Uncommon oligodendrogliomas. 罕见的少突胶质瘤。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_29
J Escalona-Zapata
{"title":"Uncommon oligodendrogliomas.","authors":"J Escalona-Zapata","doi":"10.1007/978-3-642-81553-9_29","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_29","url":null,"abstract":"","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"94-6"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17988503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Sträussler's disease. Straussler的疾病。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01
F Seitelberger
{"title":"Sträussler's disease.","authors":"F Seitelberger","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"341-3"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histopathological findings in adrenoleukodystrophy autopsy report of a boy aged 11 years and 11 months. 11岁11个月男孩肾上腺脑白质营养不良的尸检报告。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_64
R Schnabel, C Gerhard
{"title":"Histopathological findings in adrenoleukodystrophy autopsy report of a boy aged 11 years and 11 months.","authors":"R Schnabel,&nbsp;C Gerhard","doi":"10.1007/978-3-642-81553-9_64","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_64","url":null,"abstract":"<p><p>Clinical and pathohistological findings of a boy who died of adrenoleukodystrophy at the age of 11 years and 11 months are reported. Special features are the advanced diffuse demyelination of cerebral and cerebellar white matter as well as the \"burnt-out\" stage of myelin breakdown with fibrous gliosis. The leukodystrophic process is accompanied by secondary loss of axons with marked atrophy of grey matter in the whole of the brain stem, dentates and cerebellar cortex of the Purkinje cell type. The degeneration of nerve fibres is considered as a complex mechanism, which is not restricted to the Wallerian type. -- Only free cholesterol was shown by histochemical tests in the preserved myelin sheaths. Free and esterified cholesterol was found in the adrenal cortical cells. The lack of detectable cholesteryl esters in the sparse sudanophilic macrophages was unexpected. This finding may be attributed to the sensitivity of the histochemical method or to interference by achromogenic 7-ketocholesterol.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"215-8"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Ultrastructural variability of demyelinating lesions in experimental allergic encephalomyelitis and multiple sclerosis. 实验性过敏性脑脊髓炎和多发性硬化症脱髓鞘病变的超微结构变异性。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_52
H Lassmann, K Kitz, H M Wisniewski
{"title":"Ultrastructural variability of demyelinating lesions in experimental allergic encephalomyelitis and multiple sclerosis.","authors":"H Lassmann,&nbsp;K Kitz,&nbsp;H M Wisniewski","doi":"10.1007/978-3-642-81553-9_52","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_52","url":null,"abstract":"","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"173-5"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Tissue alterations induced by radio- and chemotherapy in brain with malignant gliomas. 脑恶性胶质瘤放化疗所致的组织改变。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_33
D Schiffer, R Soffietti, M T Giordana, L Tarenzi
{"title":"Tissue alterations induced by radio- and chemotherapy in brain with malignant gliomas.","authors":"D Schiffer,&nbsp;R Soffietti,&nbsp;M T Giordana,&nbsp;L Tarenzi","doi":"10.1007/978-3-642-81553-9_33","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_33","url":null,"abstract":"<p><p>35 brains with malignant gliomas treated by surgery, radiotherapy and chemotherapy and processed by means of the \"complete study\" technique have been studied. The preliminary results are reported. Many types of changes have been observed. Areas of coagulative necrosis with vessel alterations and teleangectasias are present around the tumor in many cases. Different pathologic aspects are observed distant from the tumor. Edema both in the homo - and contralateral hemisphere is constantly present. Severe edema with demyelination, axon disappearance and loss of cells is frequently found associated with prolonged survival. Often it is accompanied by wide or small areas filled with macrophages. Spongio-necrosis in the white matter of contralateral temporal lobe has been observed in two cases and telangiectasias areas have been found in another one. The relation between changes and treatment is discussed.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"109-10"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Ultrastructural and morphometric investigations on the mechanism of neurotransmitter release from synaptic vesicles. 突触小泡释放神经递质机制的超微结构和形态学研究。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_109
J Dymecki, M Walski, E Medyńska
{"title":"Ultrastructural and morphometric investigations on the mechanism of neurotransmitter release from synaptic vesicles.","authors":"J Dymecki,&nbsp;M Walski,&nbsp;E Medyńska","doi":"10.1007/978-3-642-81553-9_109","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_109","url":null,"abstract":"<p><p>The mechanism of neurotransmitter release from synaptic vesicles as the results of neuron excitation is not quite clear. It is believed, that this process may occur by way of exocytosis into the synaptic cleft directly from the cytosol to the cleft. Ultrastructural-morphometric analysis was attempted of the synaptic vesicles from the motor cortex of mice. As stimulation model an audiogenic epileptic seizure was used. The method of ZIO impregnation was applied, which according to Kawana (7) allowed to visualise the presence of a neurotransmitter in synaptic vesicles. Morphometric analysis consisted in counting the synaptic vesicles ZIO-positive, filled with neurotransmitter, and ZIO-negative, empty ones, in 3 successive zones of the synaptic bouton in the initial and end phases of seizures. As the result of excitation the number of ZIO-positive-synaptic vesicles diminished significantly whereas the number of ZIO-negative ones did not increase proportionally. This indicates that the \"dark\" vesicles do not change into the \"clear\" ones, but they disappear completely. The applied method did not allow us to precisely establish vesicle translocation toward the synaptic cleft. Nevertheless the considerable reduction of their number with the percentual distribution of vesicles remaining the same within the particular zones of bouton, may indicate, under the assumption of translocation of vesicles, that they disappear close to the cleft, probably by way of exocytosis.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"381-5"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17178540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Pentazocine-induced neuromuscular syndromes: clinical, immunological and histopathological studies in two cases. pentazocine诱导的神经肌肉综合征:两例临床、免疫学和组织病理学研究。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_72
C Mariani, G Meola, P L Meroni, C Guaita, G Scarlato
{"title":"Pentazocine-induced neuromuscular syndromes: clinical, immunological and histopathological studies in two cases.","authors":"C Mariani,&nbsp;G Meola,&nbsp;P L Meroni,&nbsp;C Guaita,&nbsp;G Scarlato","doi":"10.1007/978-3-642-81553-9_72","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_72","url":null,"abstract":"<p><p>Two cases of pentazocine-induced neuromuscular syndrome in addicted patients are reported. Histochemical and quantitative histographic analyses of muscle biopsies performed in areas distant from site of injection, disclosed type 2 atrophy. A generalized myotoxic effect of pentazocine is suggested.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"246-8"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-3-642-81553-9_72","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17511261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Congenital neuromuscular disorder with predominant mitochondrial changes in type II muscle fibers. 先天性神经肌肉疾病，主要是II型肌纤维线粒体改变。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_81
M Fardeau, F M Tomé, J C Rolland
{"title":"Congenital neuromuscular disorder with predominant mitochondrial changes in type II muscle fibers.","authors":"M Fardeau,&nbsp;F M Tomé,&nbsp;J C Rolland","doi":"10.1007/978-3-642-81553-9_81","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_81","url":null,"abstract":"<p><p>The muscle biopsy of a young boy presenting a marked hypotrophy of stature and weight, proximal muscle weakness, uncertain gait, and partial hearing loss, showed an abnormal distribution of the mitochondrial activities in type II muscle fibers by histochemical methods. Electron microscopy confirmed the presence of giant mitochondria in these muscle fibers, and at a lesser degree in some type I fibers. These findings contrast with the usual type I predominance of the mitochondrial changes in the different \"mitochondrial\" myopathies.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"279-82"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17511262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
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