{"title":"Neuropathological findings in autonomic nervous system of alimentary tract of rat after application of catecholamines.","authors":"A Jedrzejewska, M Ostenda","doi":"10.1007/978-3-642-81553-9_80","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_80","url":null,"abstract":"","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"273-5"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17987812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Alpha-bungarotoxin-induced motor end-plate sprouting.","authors":"M Swash, M S Schwartz, M K Sargeant","doi":"10.1007/978-3-642-81553-9_88","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_88","url":null,"abstract":"","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"308-9"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G Meola, E Scarpini, L Manfredi, C Mariani, G Scarlato
{"title":"Pentazocine-blocked myogenesis in human foetal muscle cultures.","authors":"G Meola, E Scarpini, L Manfredi, C Mariani, G Scarlato","doi":"10.1007/978-3-642-81553-9_89","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_89","url":null,"abstract":"<p><p>A critical review of the published cases reports suggests that the muscle changes could be induced by Pentazocine by mechanisms other than local myotoxicity. The mechanism of myotoxicity in Pentazocine-myopathy remains uncertain and for this reason a tissue culture study was performed in order to investigate the close relationship between myopathy and Pentazocine. The effects of Pentazocine on the extent of myogenesis in human foetal muscle cultures were investigated. The phase contrast study, the light microscopy the quantitative assessment of myogenesis (the number of nuclei incorporated into myotubes were counted and expressed as a percentage of the total number of nuclei) showed a complete block of myogenesis in Pentazocine treated culture and a delayed fusion process was present in D-arabinofuranosylcytosine (Ara-C)-Pentazocine-treated cultures. The present preliminary data, however, suggest that muscle stem cells could participate in the replacement of skeletal muscle by fibrous tissue in neuromuscular syndrome induced by Pentazocine.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"310-2"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of lactic acidosis in the ischemic nerve cell injury.","authors":"H Kalimo, S Rehncrona, B Söderfeldt","doi":"10.1007/978-3-642-81553-9_6","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_6","url":null,"abstract":"<p><p>Severe incomplete cerebral ischemia of 30 min duration with CBF below 5% of normal was induced in rats by clamping both carotids and lowering BP. One group of rats were fasting (f-rats), while the other was infused with glucose before induction of the ischemia (g-rats). In f-rats the lactate accumulating in the cerebral cortex was about 15 mumol . g-1, whereas in g-rats it rose to about 35 mumol . g-1. In f-rats considerable recovery of the energy state and electrical activity occurred during recirculation, whereas in g-rats the energy failure persisted with no electrical activity reappearing. In f-rats the structural alterations were of minor severity, but in g-rats extensive progressive tissue damage was seen. The data indicate that the degree of tissue lactic acidosis has pronounced effects on the development of irreversible ischemic nerve cells injury.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"20-2"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Imported lyssa in Hungary.","authors":"A Guseo, G Nádor, G Pálffy","doi":"10.1007/978-3-642-81553-9_45","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_45","url":null,"abstract":"<p><p>A 14 year old male lived for 5 years in Nigeria, 5 weeks after returning to Hungary he became ill and died within 3 days after a sudden cardiac arrest. Neuropathology revealed rabies. No contamination with animals or infected persons could be detected. The possibility of rabies related (Mokola) virus disease couldn't be excluded.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"150-1"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abnormalities in the macroscopically normal white matter in cases of mild or spinal multiple sclerosis (MS).","authors":"I V Allen, G Glover, R Anderson","doi":"10.1007/978-3-642-81553-9_53","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_53","url":null,"abstract":"<p><p>In a study of a series of mild and spinal varieties of multiple sclerosis the following histological changes have been found in the macroscopically normal white matter: 1. Marked astrocytic proliferation. 2. Some sclerosis of blood vessels. 3. Some perivascular inflammation. 4. Occasional unsuspected demyelination.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"176-8"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Morphological studies in malignant tumors of the peripheral nervous system (neurofibrosarcoma, malignant schwannoma, schwann cell sarcoma).","authors":"R Flossdorf, V Reinhardt, L Gerhard","doi":"10.1007/978-3-642-81553-9_39","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_39","url":null,"abstract":"<p><p>9 cases of malignant tumors of the peripheral nerve sheaths have been observed and their morphology including ultrastructures have been studied. 5 cases could be classified as neurofibrosarcomas, I as a Schwann cell sarcoma. Another cases may be grouped with the melaninproducing Schwann cell sarcomas and 2 cases with the \"epitheloid Schwann cell sarcomas\". The latter group, their separation or their connection to soft tissue sarcomas and to the \"medullo-epitheliomas\" of peripheral nerves are discussed.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"129-33"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Calzetti, F Gemignani, A Lechi, V Pietrini, F Tagliavini
{"title":"Progressive supranuclear palsy in the course of subclavian steal syndrome.","authors":"S Calzetti, F Gemignani, A Lechi, V Pietrini, F Tagliavini","doi":"10.1007/978-3-642-81553-9_106","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_106","url":null,"abstract":"<p><p>A 70-year-old man manifested during four years a progressive clinical picture consisting in palsy of gaze, axial rigidity, disorders of standing and gait, dysarthria, dysphagia. Neuroradiological investigations demonstrated proximal thrombosis of the left subclavian artery with subclavian steal. At necropsy, degenerative changes in several areas of the basal ganglia and brain stem, with presence of globose neurofibrillary tangles, were found, consistently with the pathologic pattern of the Progressive Supranuclear Palsy (PSP). The association of PSP and subclavian steal syndrome has not been previously reported, to our knowledge. We hypothesize that chronic ischemia, due to subclavian steal syndrome, in the vertebral basilar system and its watershed versus carotid system may have favoured the appearance, in these same areas, of the changes of the PSP.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"372-4"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17990143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Morphological changes in the brains of female patients who died in connection with pregnancy or delivery.","authors":"M Majak, J Majak, W Papierz","doi":"10.1007/978-3-642-81553-9_107","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_107","url":null,"abstract":"<p><p>The authors examined 23 brains of female patients who died during pregnancy or after delivery. Four clinical groups were distinguished: 1. sepsis, 2. gestosis, 3. patients with cardiac diseases, 4. other cases of death. General autopsy on all the dead patients was performed. Macroscopically the brain revealed the signs of oedema and herniationes. Microscopic findings showed in the sepsis and gestosis groups, distinct changes in small blood vessels. Their walls were often statified and impregnated with fibrin. In the cases with the DIC syndrome microthrombosis could be seen. Only in 2 patients cerebral arterial occlusion was noted. Neurons revealed the secondary changes described as anoxic encephalopathy.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"375-5"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17990144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}