Acta neuropathologica. Supplementum最新文献

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Neuropathological characteristics of beta irradiation induced brain edema. 辐照致脑水肿的神经病理特征。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_21
E Csanda, S Komoly, A Takáts, A Szücs
{"title":"Neuropathological characteristics of beta irradiation induced brain edema.","authors":"E Csanda, S Komoly, A Takáts, A Szücs","doi":"10.1007/978-3-642-81553-9_21","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_21","url":null,"abstract":"","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"67-9"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17986107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Some developmental aspects of morphology of submucosal and myenteric ganglia of alimentary tract. 消化道粘膜下节和肌肠神经节形态发育的一些方面。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_78
A Jedrzejewska, J Ortowska, M Kobuszewska-Faryna
{"title":"Some developmental aspects of morphology of submucosal and myenteric ganglia of alimentary tract.","authors":"A Jedrzejewska, J Ortowska, M Kobuszewska-Faryna","doi":"10.1007/978-3-642-81553-9_78","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_78","url":null,"abstract":"","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"268-70"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17987810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glucose utilization during chromatolysis: a 14C deoxyglucose study. 染色质溶解过程中的葡萄糖利用:一项14C脱氧葡萄糖研究。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_9
W Kreutzberg, H Emmert
{"title":"Glucose utilization during chromatolysis: a 14C deoxyglucose study.","authors":"W Kreutzberg,&nbsp;H Emmert","doi":"10.1007/978-3-642-81553-9_9","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_9","url":null,"abstract":"<p><p>After transection of the facial and hypoglossal nerves, rats were injected with 14C 2-deoxyglucose. Contact-autoradiographs of histological sections showed increased radioactivity in the motor nuclei of the operated side between 1 and 28 days post operation. This suggests an increase of glucose utilization and thus an enhanced energy supply to the facial and hypoglossal nuclei during the process of axonal reaction.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"29-30"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17987814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
An unusual case of meningeal gliomatosis. 罕见脑膜胶质瘤病1例。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_30
A Simonati, C Mazza, N Rizzuto
{"title":"An unusual case of meningeal gliomatosis.","authors":"A Simonati,&nbsp;C Mazza,&nbsp;N Rizzuto","doi":"10.1007/978-3-642-81553-9_30","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_30","url":null,"abstract":"<p><p>A case of meningeal gliomatosis following a primary spinal cord tumor is reported. The clinico-pathological features of this unusual extension of a spinal glioma are described. The rare incidence of this malignancy and its occurrence in young patients only are stressed. The possible pathophysiological events leading to the diffuse dissemination of the neoplastic cells are discussed.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"97-100"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17988504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Ophthalmoplegia plus: neuropathological and metabolic studies with a therapeutic trial in seven cases. 眼麻痹加:神经病理和代谢研究伴7例治疗试验。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_91
G Pellegrini, G Scarlato, M Moggio
{"title":"Ophthalmoplegia plus: neuropathological and metabolic studies with a therapeutic trial in seven cases.","authors":"G Pellegrini,&nbsp;G Scarlato,&nbsp;M Moggio","doi":"10.1007/978-3-642-81553-9_91","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_91","url":null,"abstract":"<p><p>Seven cases of chronic progressive external ophthalmoplegia (CPEO) have been studied. They all present palpebral ptosis, slowly progressive ophthalmoparesis without diplopia, descending myopathy and hypoacusia. Additional symptoms were small stature in 5 cases, vestibulo-cerebellar dysfunction in 4 cases, cardiac conductive defects in 6 cases, pigmentary degeneration of the retina in 2 cases, endocrine abnormalities in 2 cases. Muscle biopsy displays in all patients numerous ragged red fibers with typical mitochondrial changes, glycogen accumulation and abnormal amounts of lipid droplets. Metabolic studies reveal in all cases abnormal levels of pyruvic and lactic acid both in basal condition and after an oral glucose load. All the patients have been treated with pyridoxine-alpha-ketoglutarate (PAK). This substance is known to reduce pyruvic and lactic acid concentration in normal subjects after muscular exercise. Two months later a reduction of blood pyruvic and lactic acid both in normal condition and after oral glucose load was observed. The AA. discuss the possible physiological mechanism which can explain their findings.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"317-9"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Neuromuscular changes in hypertrophic cardiomyopathy. 肥厚性心肌病的神经肌肉改变。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_93
O Franch, A Cabello, J Iglesias
{"title":"Neuromuscular changes in hypertrophic cardiomyopathy.","authors":"O Franch,&nbsp;A Cabello,&nbsp;J Iglesias","doi":"10.1007/978-3-642-81553-9_93","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_93","url":null,"abstract":"<p><p>Clinical, electrophysiological and histological studies of skeletal muscle were performed in 12 patients with primary hypertrophic cardiomyopathy trying to add more information about the skeletal muscle affectation in this disease. Eight cases showed mild increase in serum enzymes. All of the patients showed slight abnormalities in the electrophysiologic studies: four had abnormal conduction velocities in peripheral nerve, another four a myopathic pattern in the EMG and four a mixed pattern. Histologically only 2 patients showed signs of a denervation atrophy. The most common alterations found were non-specific (isolated fibre atrophy, disorganization of the myofibrillar network and type II atrophy).</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"323-7"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuropathology of various types of Niemann-Pick disease. 不同类型尼曼-匹克病的神经病理学。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_60
M Elleder, A Jirásek
{"title":"Neuropathology of various types of Niemann-Pick disease.","authors":"M Elleder,&nbsp;A Jirásek","doi":"10.1007/978-3-642-81553-9_60","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_60","url":null,"abstract":"<p><p>A comparative neuropathological and histochemical study was performed on the brains of seven cases of NPD. In type A (two cases), besides the neuronal storage of SM, a widespread endothelial storage of a neutral glycosphingolipid was found. In one case a pseudosystemic lesion of the pallido-nigral system was observed. In type B (one case) the only finding was the endothelial storage of SM. In type C (four cases) the degree of neuronal storage distension contrasted considerably with a very low amount of lipid demonstrable histochemically in fixed brains. Only in one case, focal neuronal storage of a phosphoglyceride could be proved. However, in peripheral neurons (of unfixed appendix) the phosphoglycerides were clearly predominating (one case). A remarkable and constant finding in each case of the series was a widespread neuroaxonal dystrophy with various topical maxima (thalamus, dentate nuclei). The significance of the findings are discussed in relation to the present status of knowledge of this type.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"201-3"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Fatty acid patterns in brain, fibroblast, leukocyte and body fluid lipids in adrenoleukodystrophy. 肾上腺脑白质营养不良患者脑、成纤维细胞、白细胞和体液脂质的脂肪酸模式。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_63
B Molzer, H Bernheimer, K Toifl
{"title":"Fatty acid patterns in brain, fibroblast, leukocyte and body fluid lipids in adrenoleukodystrophy.","authors":"B Molzer,&nbsp;H Bernheimer,&nbsp;K Toifl","doi":"10.1007/978-3-642-81553-9_63","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_63","url":null,"abstract":"<p><p>Fatty acid patterns of certain tissue and body fluid lipids of ALD and control cases were investigated by thin layer and gas chromatography. A high percentage (55.2%) of VLFA was found in the ALD brain white matter cholesterol esters; this was mainly due to increased proportions of 26:0, 25:0, 26:1 and greater than 26 C fatty acids. The percentage of VLFA in the white matter cholesterol esters of pathological controls with myelin breakdown of different etiology was low (0.4-7.1%). In the fibroblast total lipids of an ALD patient an increase of 26:0 and 25:0 fatty acids was found. Moderately increased proportions of hexacosanoic acid were observed in the leukocyte total lipids of 2 severely affected ALD patients, but not in a slightly as well as in a possible affected case. No accumulation of VLFA was detected in cholesterol ester, triglyceride and free fatty acid fractions in the CSF of an ALD patient and in ALD serum sphingomyelin. Our results substantiate the specificity of VLFA accumulation in the white matter cholesterol esters of ALD brain and lend some further evidence to the view that a generalized impairment of VLFA metabolism seems to be present in this disease.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"211-4"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Biochemical and morphological studies on a case of systemic carnitine deficiency. 1例系统性肉碱缺乏症的生化及形态学研究。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_65
C Cerri, G Meola, G Scarlato
{"title":"Biochemical and morphological studies on a case of systemic carnitine deficiency.","authors":"C Cerri,&nbsp;G Meola,&nbsp;G Scarlato","doi":"10.1007/978-3-642-81553-9_65","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_65","url":null,"abstract":"<p><p>The authors report a patient with systemic carnitine deficiency in which, despite restoration of normal serum carnitine level by therapy, the fatal course of the disease progressed. Postmortem studies of cardiac muscle with Oil red O failed to show lipid accumulation which was still present in muscle and liver. Carnitine level in liver was less than 10% of the controls values; total carnitine in muscle was 50% of the controls with differences in its esterification pattern; whereas the free carnitine was 1/10 of normal, the long chain esterified one was 3 times higher than the control. Heart carnitine content was normal. The authors suggest that although no therapeutic effects were detected in skeletal muscle, the normal carnitine content and the absence of lipidosis in the heart suggest that carnitine therapy may have been beneficial in our patient enabling the heart to utilize fatty acids.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"219-20"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Germinomas of the brain. Light and electron microscopic study. A report of seven cases. 大脑的生殖细胞瘤。光学和电子显微镜研究。报告七个病例。
Acta neuropathologica. Supplementum Pub Date : 1981-01-01 DOI: 10.1007/978-3-642-81553-9_32
J Hassoun, D Gambarelli, J F Pellissier, D Henin, M Toga
{"title":"Germinomas of the brain. Light and electron microscopic study. A report of seven cases.","authors":"J Hassoun,&nbsp;D Gambarelli,&nbsp;J F Pellissier,&nbsp;D Henin,&nbsp;M Toga","doi":"10.1007/978-3-642-81553-9_32","DOIUrl":"https://doi.org/10.1007/978-3-642-81553-9_32","url":null,"abstract":"<p><p>The authors report seven cases of intracerebral germinomas studied on autopsy and/or biopsy material. Electron microscopy was done in five cases. Tumors were located on the middle line of the brain (pineal area, suprasellar region, third ventricle). Light microscopic features were stereotyped with PAS + round tumor cells and inflammatory mononuclear cells. By electron microscopy, fenestrated nucleoli, glycogen storage and annulate lamellae were always found, as well as a striking macrophagic activity of histiocytes. This immune reaction is supposed to contribute to the relatively favorable prognosis of these original brain tumors.</p>","PeriodicalId":75397,"journal":{"name":"Acta neuropathologica. Supplementum","volume":"7 ","pages":"105-8"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17989764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
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