Vertex (Buenos Aires, Argentina)最新文献_第3页

Carlos Castilla del Pino: From Neuropsychiatry to Dialectical Anthropology 卡洛斯·卡斯蒂利亚·德尔皮诺：从神经精神病学到辩证人类学。

Vertex (Buenos Aires, Argentina) Pub Date : 2026-07-10 DOI: 10.53680/vertex.v37i172.1020

Norberto Aldo Conti

引用次数: 0

Editorial. 社论。

Vertex (Buenos Aires, Argentina) Pub Date : 2026-07-10

Silvia Mazaira, Juan Carlos Stagnaro

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Anhedonia as a Transdiagnostic Phenomenon: Neurobiological, Clinical, and Therapeutic Approaches 焦虑作为一种跨诊断现象：神经生物学、临床和治疗方法。

Vertex (Buenos Aires, Argentina) Pub Date : 2026-07-10 DOI: 10.53680/vertex.v37i172.1017

Paula Mirabel Révora, Mario Levin, Fernando Torrente, Pedro Damián Gargoloff, María Florencia Iveli

{"title":"Anhedonia as a Transdiagnostic Phenomenon: Neurobiological, Clinical, and Therapeutic Approaches","authors":"Paula Mirabel Révora, Mario Levin, Fernando Torrente, Pedro Damián Gargoloff, María Florencia Iveli","doi":"10.53680/vertex.v37i172.1017","DOIUrl":"10.53680/vertex.v37i172.1017","url":null,"abstract":"Anhedonia, classically defined as the inability to experience pleasure, was introduced in 1897 by the French philosopher and psychologist Théodule Armand Ribot. Although this term is still used, it has undergone conceptual modifications because the dichotomy of the original description is insufficient to capture the complexity of its components (Pérez Rincón, 2014). The hedonic experience is a dynamic and cyclical process that begins with a state with an individual reference range, known as hedonic tone, which determines each person’s capacity to experience pleasure and happiness.\u0000Currently, anhedonia is considered a transdiagnostic, multidimensional, and dynamic construct consisting of multiple attributes or valences whose combination determines a wide variety of behavioral phenotypes. These may be transiently altered or represent a more enduring trait. The presence of anhedonia in various psychopathological disorders is associated with greater severity, a worse prognosis, and an increased risk of suicide. For this reason, effective psychotherapeutic and pharmacological treatments are essential. The objective of this paper, a narrative review, was to offer an expert clinical opinion, summarizing the evidence on some anhedonia phenotypes and their potential treatments. Three adapted clinical vignettes are also included as examples.","PeriodicalId":75297,"journal":{"name":"Vertex (Buenos Aires, Argentina)","volume":"37 172, abr.-jun.","pages":"49-71"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148440467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Off-label prescription of antiepileptic drugs in psychiatric inpatients 精神病住院治疗中抗癫痫药物的标签外处方。

Vertex (Buenos Aires, Argentina) Pub Date : 2026-07-10 DOI: 10.53680/vertex.v37i172.1016

Pamela S Sacco

{"title":"Off-label prescription of antiepileptic drugs in psychiatric inpatients","authors":"Pamela S Sacco","doi":"10.53680/vertex.v37i172.1016","DOIUrl":"10.53680/vertex.v37i172.1016","url":null,"abstract":"Introduction: Off-label prescription of antiepileptic drugs (AEDs) is highly frequent in daily clinical practice. Most of these drugs have multiple mechanisms of action, which can explain their efficacy in the treatment of various non-epileptic central nervous system (CNS) disorders, both in neurological and psychiatric conditions.Objective: The objective of this study was to analyze the use of AEDs in patients admitted to psychiatric hospital.Methods: Clinical records of 205 patients were retrospectively reviewed to collect the following variables: demographic data, clinical diagnosis, associated comorbidities, and pharmacological treatments.Results: Antiepileptic drugs were prescribed to 43.9% of the patients (and 7.31% had more than one AED indicated). Off-label prescription was used in 65.55% of cases, and 10.00% of patients had dual prescriptions (co-occurrence of on-label and off-label indications). The most frequent diagnoses associated with off-label use were schizophrenia (33,33%), intellectual disability without epilepsy (31,11%), and psychosis associated with problematic substance use (17,78%). Valproic acid was the most frequently prescribed off-label drug (p<0.0001).Discussion: Despite emerging as promising options, it is essential to conduct further research to clarify the risks and benefits of using these drugs in the field of psychiatry.","PeriodicalId":75297,"journal":{"name":"Vertex (Buenos Aires, Argentina)","volume":"37 172, abr.-jun.","pages":"41-48"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148440535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuropsychological performance in euthymic bipolar disorder with and without suicide attempts: a comparative study with healthy controls 双相情感障碍在有或没有自杀企图的安乐死下的神经心理表现：与健康对照的比较研究。

Vertex (Buenos Aires, Argentina) Pub Date : 2026-07-10 DOI: 10.53680/vertex.v37i172.1012

Ester Romero, Lucila Tannenhaus, Gustavo Vázquez

{"title":"Neuropsychological performance in euthymic bipolar disorder with and without suicide attempts: a comparative study with healthy controls","authors":"Ester Romero, Lucila Tannenhaus, Gustavo Vázquez","doi":"10.53680/vertex.v37i172.1012","DOIUrl":"10.53680/vertex.v37i172.1012","url":null,"abstract":"Objective: To compare the neuropsychological performance of euthymic bipolar patients with (CIS) and without suicide attempts (SIS), relative to healthy controls (HC).Methods: This cross-sectional study included 31 patients (CIS n=15; SIS n=16) and 46 independent HC. The battery comprised RAVLT, Rey Complex Figure, WAIS-III Digit Span, TMT-A/B, WCST, Stroop, and COWAT-FAS. CIS–SIS comparisons were conducted with Student’s t tests; CIS/SIS vs HC with Welch’s t tests; two-tailed p values uncorrected for multiplicity.Results: CIS and SIS showed broadly similar performance in episodic memory, forward working memory, Stroop, and verbal fluency; the only significant between-patient difference was a lower number of WCST categories in CIS. Compared with HC, both groups performed worse on verbal memory (RAVLT) and showed slowing on TMT-B. However, a differential pattern emerged: CIS displayed additional deficits in TMT-A and backward digits, whereas SIS did not differ from HC in these tests. Overall, CIS showed significant impairment relative to HC in three of four measures (RAVLT, TMT-A, and backward digits), while SIS differed in two (RAVLT and TMT-B).Conclusions: Direct CIS–SIS differences were modest (only WCST categories), but contrasts with controls revealed partially distinct profiles. The findings suggest that deficits in processing speed and working memory may be more pronounced in patients with a history of suicide attempts. These results should be interpreted as exploratory, and replication in larger samples and longitudinal designs is warranted.","PeriodicalId":75297,"journal":{"name":"Vertex (Buenos Aires, Argentina)","volume":"37 172, abr.-jun.","pages":"7-14"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148440463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychiatric adverse effects in hemodialysis patients with chronic kidney disease: a clinical dimension with prognostic implications 慢性肾脏疾病血液透析患者的精神不良影响：具有预后影响的临床维度。

Vertex (Buenos Aires, Argentina) Pub Date : 2026-07-10

Jorge Andrés Hernández Navas, Juliana Gelvez Mantilla, Valentina Hernández Navas

引用次数: 0

Impact of social media usage time on depression and generalized anxiety in medical students in Bolivia 社交网络使用时间对玻利维亚医科学生普遍抑郁和焦虑的影响。

Vertex (Buenos Aires, Argentina) Pub Date : 2026-07-10 DOI: 10.53680/vertex.v37i172.1015

José Luis Villca Villegas, Alvaro Andre Vargas Aguilar, Natália Velasquez Oliveira, Maria Vitoria Rodrigues Magalhães, Andrei Jair Nuñez Albornoz, Ingrid Nayara Rodrigues Da Fonseca

{"title":"Impact of social media usage time on depression and generalized anxiety in medical students in Bolivia","authors":"José Luis Villca Villegas, Alvaro Andre Vargas Aguilar, Natália Velasquez Oliveira, Maria Vitoria Rodrigues Magalhães, Andrei Jair Nuñez Albornoz, Ingrid Nayara Rodrigues Da Fonseca","doi":"10.53680/vertex.v37i172.1015","DOIUrl":"10.53680/vertex.v37i172.1015","url":null,"abstract":"Introduction: Social media has transformed global communication, but excessive use is linked to mental health issues\u0000such as depression and anxiety. Medical students are a vulnerable group due to the inherent stressors of their academic training. This study examines the relationship between social media use and depressive-anxious symptoms in medical students at Franz Tamayo University.Methods: A cross-sectional study was conducted with 210 students. The Beck Depression and Anxiety Inventory was used, along with questionnaires on daily social media use and platform preferences. Descriptive statistics and regression models were applied to assess the association between usage time and symptoms.Results: Participants used social media for an average of 5.29 hours per day, with TikTok being the most used app (79.52%). Mean depression and anxiety scores were 15.6 (SD = 13.2) and 15.4 (SD = 13.0), respectively.\u0000Each additional hour of use was associated with 0.51 more points in depression (p = 0.030) and 0.72 more points\u0000in anxiety (p = 0.002). Students with a history of anxiety scored 8.59 points higher in anxiety (p = 0.012), and those with a history of depression scored 14.47 points higher (p < 0.001). The explained variance was 8.2% for anxiety (R² = 0.082) and 12.3% for depression (R² = 0.123).Discussion: A significant association was found between excessive social media use and poor mental health, although other factors also play a role.Conclusion: Excessive social media use is associated with higher levels of anxiety and depression. Universities should promote digital well-being initiatives to improve medical students' mental health.","PeriodicalId":75297,"journal":{"name":"Vertex (Buenos Aires, Argentina)","volume":"37 172, abr.-jun.","pages":"33-40"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148440521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abnormal (disturbed) self-experiences in schizophrenia spectrum disorders: the qualitative aspect 精神分裂症谱系中的自我异常经历（改变）：定性方面。

Vertex (Buenos Aires, Argentina) Pub Date : 2026-07-10 DOI: 10.53680/vertex.v37i172.1018

Marco Fierro, Abel Guerrero, Juan Toro

{"title":"Abnormal (disturbed) self-experiences in schizophrenia spectrum disorders: the qualitative aspect","authors":"Marco Fierro, Abel Guerrero, Juan Toro","doi":"10.53680/vertex.v37i172.1018","DOIUrl":"10.53680/vertex.v37i172.1018","url":null,"abstract":"Over the past 30 years, psychopathology has shown a growing interest in the study of the self and its alterations from a phenomenological perspective, and a number of studies have appeared on the anomalous experience in schizophrenia. Publications on these topics are scarce in Spanish-language psychiatry. For this reason, this article presents a narrative review, first, of the concept of the basic or minimal self and, second, of the qualitative aspects of alterations in the basic self in schizophrenia spectrum disorders and the prodrome of schizophrenia. The basic or minimal self has a similar structure in all human beings. It corresponds to an implicit sense of self-presence previous to any reflection or elaborate cognitive process, to being immersed in the world from a first-person perspective, to the point of reference and belonging of all mental phenomena. It is pre-reflective, non-verbal, and immediately present in each and every experience. Anomalous self-experiences, or self-disturbances, are considered core phenotypic features of schizophrenia spectrum disorders. They are experiences in which the first-person perspective or one's status as the subject of experience or\u0000action is somehow distorted.","PeriodicalId":75297,"journal":{"name":"Vertex (Buenos Aires, Argentina)","volume":"37 172, abr.-jun.","pages":"72-81"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148440547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eric David Wittkower: los estudios psicosomáticos entre Europa y América. Eric David Wittkower：欧洲和美国之间的身心研究。

Vertex (Buenos Aires, Argentina) Pub Date : 2026-04-10 DOI: 10.53680/vertex.v37i171.981

Norberto Aldo Conti

引用次数: 0

Evaluación de los estereotipos negativos hacia la vejez en población mayor de 60 años en el ámbito de la Ciudad de Buenos Aires. 评估布宜诺斯艾利斯市60岁以上人口对老年的负面刻板印象。

Vertex (Buenos Aires, Argentina) Pub Date : 2026-04-10 DOI: 10.53680/vertex.v37i171.972

Cecilia M Serrano, Josefina Barber Otero, Lucía Brolese, Marcos G Sorbara

{"title":"Evaluación de los estereotipos negativos hacia la vejez en población mayor de 60 años en el ámbito de la Ciudad de Buenos Aires.","authors":"Cecilia M Serrano, Josefina Barber Otero, Lucía Brolese, Marcos G Sorbara","doi":"10.53680/vertex.v37i171.972","DOIUrl":"10.53680/vertex.v37i171.972","url":null,"abstract":"Introducción: El edadismo o discriminación por edad implica actitudes negativas hacia las personas mayores, incluidas creencias, emociones y conductas. Es una construcción social inconsciente, presente desde edades tempranas y entre los mayores, que dificulta su erradicación. Limita la integración social y laboral, incrementa la soledad y constituye un factor de riesgo para el deterioro cognitivo. Este estudio utiliza el Cuestionario de Estereotipos Negativos hacia la Vejez (CENVE) para evaluar edadismo en adultos mayores de 60 años. Materiales y métodos: Estudio observacional transversal aprobado por el CEI institucional. Se distribuyó digitalmente el CENVE, que evalúa estereotipos relacionados con salud, motivación-social y carácter-personalidad, asignando puntajes según creencias negativas. También se recopilaron datos demográficos, de escolaridad y formación académica en envejecimiento. Se analizaron diferencias entre subgrupos. Resultados: Participaron 329 adultos mayores (77.8 % mujeres): 41.6 % tenían entre 60-70 años, 36.3 % entre 70-80 años, y 9.9 % más de 80 años. Un 77.8 % tenía más de 12 años de escolaridad y 16.1 % formación académica en envejecimiento. Las medianas de CENVE fueron: salud, 10 (RIC 5); motivación-social, 10 (RIC 5); carácter-personalidad, 11 (RIC 5.25). Discusión y conclusiones: La mayor escolaridad y formación académica sobre envejecimiento se asociaron con menores puntajes de CENVE. Esto sugiere que la educación podría contrarrestar estereotipos negativos. Difundir conocimiento podría reducir el auto estigma, mejorar la calidad de vida y disminuir el riesgo de deterioro en adultos mayores.","PeriodicalId":75297,"journal":{"name":"Vertex (Buenos Aires, Argentina)","volume":"37 171, ene.-mar.","pages":"7-13"},"PeriodicalIF":0.0,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147663513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0