Therapeutic advances in allergy and rhinology最新文献

{"title":"COVID-19 Incidence and Disease Course Among Patients at an Allergy Department.","authors":"Louise E van der Aa,&nbsp;Inge S van Egmond,&nbsp;Martijn van der Sluijs,&nbsp;A A Sophie den Otter,&nbsp;Nadie H M Bosmans,&nbsp;Sabine E van Beek,&nbsp;Angela Hartman,&nbsp;Niels A D Guchelaar,&nbsp;Paul L A van Daele,&nbsp;Maurits S van Maaren,&nbsp;P Martin van Hagen,&nbsp;Maud A W Hermans,&nbsp;Saskia M Rombach","doi":"10.1177/27534030231172391","DOIUrl":"https://doi.org/10.1177/27534030231172391","url":null,"abstract":"<p><strong>Background: </strong>Since the coronavirus pandemic in 2020, there is not much reported about the disease course of COVID-19 in patients with allergic diseases.</p><p><strong>Objectives: </strong>The aim of this study was to investigate the cumulative incidence and severity of COVID-19 among patients from the allergy department compared with the general Dutch population and people from their household.</p><p><strong>Design: </strong>We conducted a comparative longitudinal cohort study.</p><p><strong>Methods: </strong>In this study patients of the allergy department were included with their household members as a control group. Data from the beginning of the pandemic were systematically obtained through questionnaires by telephonic interviews and retrieved from electronic patient files between October 15, 2020 and January 29, 2021. Main outcomes were confirmed SARS-CoV-2 infection, disease duration, hospitalization, intensive care admission, and mortality. Questions regarding applied social distancing measures were inventoried as well.</p><p><strong>Results: </strong>Three hundred and eighty nine patients (median age 39.1 (18.7-84.7) years, 69.9% female) and 441 household members (median age 42.0 (18.0-91.5), 44.1% female) were included. The cumulative COVID-19 incidence in patients was higher compared with the general population (10.5% vs 5.6%, <i>P</i> < .001). In total, 41 (10.5%) patients attending the allergy clinic compared to 38 (8.6%) household members were infected with SARS-CoV-2 (<i>P</i> = .407). Median disease duration was 11.0 (0.0-61.0) days in patients compared to 10.5(1.0-232.0) days in household members (<i>P</i> = .996).</p><p><strong>Conclusion: </strong>The cumulative COVID-19 incidence in patients from the allergy cohort was higher compared with the general Dutch population, but similar compared with household members. There was no difference in symptoms, disease duration, or hospitalization rate between the allergy cohort and their household members.</p>","PeriodicalId":75217,"journal":{"name":"Therapeutic advances in allergy and rhinology","volume":"14 ","pages":"27534030231172391"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9868981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nasal Cavity Length or Analyzed Nasal Segment of Acoustic Rhinometry in Thai Adults.","authors":"Paraya Assanasen,&nbsp;Triphoom Suwanwech,&nbsp;Bannapuch Pinkaew,&nbsp;Anupa Khongsri,&nbsp;Phawin Keskool","doi":"10.1177/27534030231171089","DOIUrl":"https://doi.org/10.1177/27534030231171089","url":null,"abstract":"<p><strong>Background: </strong>Nasal cavity length (NCL) is important for determining analyzed nasal segment (ANS) of acoustic rhinometry (AR). AR is a technique for nasal airway assessment which nasal cross-sectional areas and nasal volume (NV) are obtained. NCL or ANS is the important parameter to determine NV measured by AR. The ANS used to calculate NV in previous literatures vary from 4 to 8 cm. However, there has not been any study regarding NCL of Asians which is probably different from that of Western countries.</p><p><strong>Objectives: </strong>To measure NCL in Thai adults using nasal telescope and compared NCL between left and right sides as well as male and female as well as among age groups.</p><p><strong>Design: </strong>Prospective study.</p><p><strong>Methods: </strong>This study was performed on patients, aged 18-95 years, who underwent nasal telescopy under local anesthesia at the Department of Otorhinolaryngology, Siriraj Hospital. Baseline characteristics (sex and age) of patients were collected. NCL (from anterior nasal spine to posterior edge of nasal septum) of both nasal cavities was measured using rigid nasal telescope of 0 degree. Mean NCL length of both nasal cavities was calculated.</p><p><strong>Results: </strong>There were 1277 patients, with 498 (39%) male and 779 (61%) female. The mean ± standard deviation (SD) of NCL of male was 6 ± 0.6 cm whereas that of female was 5.7 ± 0.5 cm. There were no significant differences in NCL between left and right sides as well as among age groups in each gender (p > 0.05 all). However, male had significantly longer NCL compared with that of female (p < 0.001). The mean ± SD of NCL of total population was 5.9 ± 0.6 cm.</p><p><strong>Conclusion: </strong>The NCL of Thais was approximately 6 cm. These data are useful to determine ANS used to calculate NV when AR is performed.</p><p><strong>Plain language summaries: </strong>The length of nasal cavity (LNC) is important variable for acoustic rhinometry (AR) which is the instrument to measure nasal volume (NV). We use AR in clinical researches to diagnose and monitor the results of treatment of nose and sinus diseasesThe LNC used to calculate NV in previous studies vary from 4 to 8 cm. However, there has not been any study of LNC of Asians which is probably different from that of Western countriesWe measured LNC in 1277 Thai adults, aged 18-95 years, with 498 (39%) male and 779 (61%) female using nasal rigid endoscope and compared LNC between male and female.The average of LNC was 5.9 cm. Male had longer LNC compared with that female. The LNC of Thais was approximately 6 cm. These data are useful for AR to calculate NV.</p>","PeriodicalId":75217,"journal":{"name":"Therapeutic advances in allergy and rhinology","volume":"14 ","pages":"27534030231171089"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f0/2c/10.1177_27534030231171089.PMC10159236.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10297849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}