COVID-19 Incidence and Disease Course Among Patients at an Allergy Department.

0 OTORHINOLARYNGOLOGY
Louise E van der Aa, Inge S van Egmond, Martijn van der Sluijs, A A Sophie den Otter, Nadie H M Bosmans, Sabine E van Beek, Angela Hartman, Niels A D Guchelaar, Paul L A van Daele, Maurits S van Maaren, P Martin van Hagen, Maud A W Hermans, Saskia M Rombach
{"title":"COVID-19 Incidence and Disease Course Among Patients at an Allergy Department.","authors":"Louise E van der Aa,&nbsp;Inge S van Egmond,&nbsp;Martijn van der Sluijs,&nbsp;A A Sophie den Otter,&nbsp;Nadie H M Bosmans,&nbsp;Sabine E van Beek,&nbsp;Angela Hartman,&nbsp;Niels A D Guchelaar,&nbsp;Paul L A van Daele,&nbsp;Maurits S van Maaren,&nbsp;P Martin van Hagen,&nbsp;Maud A W Hermans,&nbsp;Saskia M Rombach","doi":"10.1177/27534030231172391","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Since the coronavirus pandemic in 2020, there is not much reported about the disease course of COVID-19 in patients with allergic diseases.</p><p><strong>Objectives: </strong>The aim of this study was to investigate the cumulative incidence and severity of COVID-19 among patients from the allergy department compared with the general Dutch population and people from their household.</p><p><strong>Design: </strong>We conducted a comparative longitudinal cohort study.</p><p><strong>Methods: </strong>In this study patients of the allergy department were included with their household members as a control group. Data from the beginning of the pandemic were systematically obtained through questionnaires by telephonic interviews and retrieved from electronic patient files between October 15, 2020 and January 29, 2021. Main outcomes were confirmed SARS-CoV-2 infection, disease duration, hospitalization, intensive care admission, and mortality. Questions regarding applied social distancing measures were inventoried as well.</p><p><strong>Results: </strong>Three hundred and eighty nine patients (median age 39.1 (18.7-84.7) years, 69.9% female) and 441 household members (median age 42.0 (18.0-91.5), 44.1% female) were included. The cumulative COVID-19 incidence in patients was higher compared with the general population (10.5% vs 5.6%, <i>P</i> < .001). In total, 41 (10.5%) patients attending the allergy clinic compared to 38 (8.6%) household members were infected with SARS-CoV-2 (<i>P</i> = .407). Median disease duration was 11.0 (0.0-61.0) days in patients compared to 10.5(1.0-232.0) days in household members (<i>P</i> = .996).</p><p><strong>Conclusion: </strong>The cumulative COVID-19 incidence in patients from the allergy cohort was higher compared with the general Dutch population, but similar compared with household members. There was no difference in symptoms, disease duration, or hospitalization rate between the allergy cohort and their household members.</p>","PeriodicalId":75217,"journal":{"name":"Therapeutic advances in allergy and rhinology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189845/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Therapeutic advances in allergy and rhinology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/27534030231172391","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"0","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Since the coronavirus pandemic in 2020, there is not much reported about the disease course of COVID-19 in patients with allergic diseases.

Objectives: The aim of this study was to investigate the cumulative incidence and severity of COVID-19 among patients from the allergy department compared with the general Dutch population and people from their household.

Design: We conducted a comparative longitudinal cohort study.

Methods: In this study patients of the allergy department were included with their household members as a control group. Data from the beginning of the pandemic were systematically obtained through questionnaires by telephonic interviews and retrieved from electronic patient files between October 15, 2020 and January 29, 2021. Main outcomes were confirmed SARS-CoV-2 infection, disease duration, hospitalization, intensive care admission, and mortality. Questions regarding applied social distancing measures were inventoried as well.

Results: Three hundred and eighty nine patients (median age 39.1 (18.7-84.7) years, 69.9% female) and 441 household members (median age 42.0 (18.0-91.5), 44.1% female) were included. The cumulative COVID-19 incidence in patients was higher compared with the general population (10.5% vs 5.6%, P < .001). In total, 41 (10.5%) patients attending the allergy clinic compared to 38 (8.6%) household members were infected with SARS-CoV-2 (P = .407). Median disease duration was 11.0 (0.0-61.0) days in patients compared to 10.5(1.0-232.0) days in household members (P = .996).

Conclusion: The cumulative COVID-19 incidence in patients from the allergy cohort was higher compared with the general Dutch population, but similar compared with household members. There was no difference in symptoms, disease duration, or hospitalization rate between the allergy cohort and their household members.

Abstract Image

Abstract Image

Abstract Image

某过敏科患者COVID-19发病率及病程
背景:自2020年冠状病毒大流行以来,关于过敏性疾病患者COVID-19病程的报道不多。目的:本研究的目的是调查过敏科患者中COVID-19的累积发病率和严重程度,并与荷兰普通人群及其家庭成员进行比较。设计:我们进行了一项比较纵向队列研究。方法:本研究将过敏科患者及其家庭成员作为对照组。在2020年10月15日至2021年1月29日期间,通过电话访谈和问卷调查系统地获取了大流行开始时的数据,并从患者电子档案中检索了数据。主要结局为确诊SARS-CoV-2感染、病程、住院、重症监护住院和死亡率。还列出了有关适用社会距离措施的问题。结果:纳入389例患者(中位年龄39.1(18.7 ~ 84.7)岁,女性占69.9%)和441例家庭成员(中位年龄42.0(18.0 ~ 91.5),女性占44.1%)。患者的COVID-19累积发病率高于普通人群(10.5% vs 5.6%, P P = .407)。患者的中位病程为11.0(0.0-61.0)天,而家庭成员的中位病程为10.5(1.0-232.0)天(P = 0.996)。结论:过敏队列患者的COVID-19累积发病率高于荷兰普通人群,但与家庭成员相似。过敏队列及其家庭成员在症状、疾病持续时间或住院率方面没有差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信