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The Journal of the Oklahoma State Medical Association最新文献

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President's Page. 总统的页面。
The Journal of the Oklahoma State Medical Association Pub Date : 2016-03-01
Woody Jenkins
{"title":"President's Page.","authors":"Woody Jenkins","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75127,"journal":{"name":"The Journal of the Oklahoma State Medical Association","volume":"109 3","pages":"85-7"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34550597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Question: In adult patients on warfarin, does-home-self-testing of prothrombin time and/or international normalized ratio provide the same outcomes compared to testing by a home health nurse or in a clinical setting? 临床问题:在华法林治疗的成年患者中，家庭自测凝血酶原时间和/或国际标准化比率与家庭保健护士或临床环境检测的结果相同吗?
The Journal of the Oklahoma State Medical Association Pub Date : 2016-03-01
May Kou Heu, Toney Welborn, Zsolt Nagykaldi
{"title":"Clinical Question: In adult patients on warfarin, does-home-self-testing of prothrombin time and/or international normalized ratio provide the same outcomes compared to testing by a home health nurse or in a clinical setting?","authors":"May Kou Heu, Toney Welborn, Zsolt Nagykaldi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75127,"journal":{"name":"The Journal of the Oklahoma State Medical Association","volume":"109 3","pages":"99-100"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900684/pdf/nihms765776.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34550598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of PACT and MHIC Programs in the Evolution of Patient Centered Mental Health Care in OkIahoma. 俄克拉何马州PACT和MHIC计划在以患者为中心的精神卫生保健发展中的影响。
The Journal of the Oklahoma State Medical Association Pub Date : 2016-02-01
Amy Liu, Phebe Tucker
{"title":"The Impact of PACT and MHIC Programs in the Evolution of Patient Centered Mental Health Care in OkIahoma.","authors":"Amy Liu, Phebe Tucker","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75127,"journal":{"name":"The Journal of the Oklahoma State Medical Association","volume":"109 2","pages":"55-8"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34384638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PRESIDENT'S PAGE. 总统的页面。
The Journal of the Oklahoma State Medical Association Pub Date : 2016-02-01
Woody Jenkins
{"title":"PRESIDENT'S PAGE.","authors":"Woody Jenkins","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75127,"journal":{"name":"The Journal of the Oklahoma State Medical Association","volume":"109 2","pages":"49-50"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34384637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bracing for reality.... 迎接现实....
The Journal of the Oklahoma State Medical Association Pub Date : 2016-02-01
J Michael Pontious
{"title":"Bracing for reality....","authors":"J Michael Pontious","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75127,"journal":{"name":"The Journal of the Oklahoma State Medical Association","volume":"109 2","pages":"47-8"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34384636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Question: In adults with COPD does roflumilast reduce the frequency of exacerbations compDared to standard therapies aIone? 临床问题:在成人COPD患者中，罗氟米司特与单独标准治疗相比是否能降低急性加重的频率?
The Journal of the Oklahoma State Medical Association Pub Date : 2016-02-01
John Marshall Huser, Jeffrey Dean Hodgden
{"title":"Clinical Question: In adults with COPD does roflumilast reduce the frequency of exacerbations compDared to standard therapies aIone?","authors":"John Marshall Huser, Jeffrey Dean Hodgden","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75127,"journal":{"name":"The Journal of the Oklahoma State Medical Association","volume":"109 2","pages":"59-60"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896480/pdf/nihms779942.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34384639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RE: November 2015 Smoking Issue. 回复:2015年11月吸烟问题。
The Journal of the Oklahoma State Medical Association Pub Date : 2016-02-01
Patrick D Lester
{"title":"RE: November 2015 Smoking Issue.","authors":"Patrick D Lester","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75127,"journal":{"name":"The Journal of the Oklahoma State Medical Association","volume":"109 2","pages":"63"},"PeriodicalIF":0.0,"publicationDate":"2016-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34384640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of In Vivo DNA Damage Induced by Very Low Doses of Mainstream and Sidestream Smoke Extracts Using a Novel Assay. 用一种新的方法检测极低剂量主流和侧流烟提取物引起的体内DNA损伤。
The Journal of the Oklahoma State Medical Association Pub Date : 2015-11-01
Vengateah Ganapathy, Ilangovan Ramachandran, David A Rubenstein, Lurdes Queimado
{"title":"Detection of In Vivo DNA Damage Induced by Very Low Doses of Mainstream and Sidestream Smoke Extracts Using a Novel Assay.","authors":"Vengateah Ganapathy, Ilangovan Ramachandran, David A Rubenstein, Lurdes Queimado","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Mainstream (MS) smoke, the main smoke inhaled by active smokers, and sidestream (SS) smoke, the main component of secondhand smoke, induce a wide range of DNA lesions. Owing to technical limitations, the in vivo levels of tobacco-induced DNA damage are unknown. Recently, the authors developed a highly sensitive primer-anchored DNA damage detection assay (PADDA) to quantify endogenous and induced DNA damage.</p><p><strong>Purpose: </strong>To quantify the in vivo levels of DNA damage induced by MS and SS smoke extracts in human cells using PADDA and define the strand-specific patterns of DNA damage and repair following exposure to diverse doses of MS and SS smoke.</p><p><strong>Methods: </strong>Human epithelial cells were exposed to escalating doses of hydrogen peroxide (H2O2), MS; or SS smoke. TP53 gene DNA damage was quantified using PADDA at various time points. DNA double-strand breaks were detected by immunofluorescence analysis of phosphorylated histone H2AX (γ-H2AX). Cell viability was determined by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay. Data were collected and analyzed by t-test in 2012-2014.</p><p><strong>Results: </strong>A dose-dependent increase in DNA damage was detected in vivo with increasing doses of H2O2, MS, and SS smoke. Even 1 hour of exposure to very low doses of MS or SS smoke resulted in significant DNA damage (p < 0.01). MS and SS smoke induced distinctive strand-specific patterns of DNA damage and DNA repair kinetics.</p><p><strong>Conclusions: </strong>Very low concentrations of MS and SS smoke induce significant DNA damage in human cells. Application of PADDA to population studies has major potential to establish biomarkers of susceptibility to tobacco-induced diseases.</p>","PeriodicalId":75127,"journal":{"name":"The Journal of the Oklahoma State Medical Association","volume":"108 11","pages":"500-8"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient Pages. HEALTH RISKS OF SMOKELESS TOBACCO. 病人的页面。无烟烟草的健康风险。
The Journal of the Oklahoma State Medical Association Pub Date : 2015-11-01
{"title":"Patient Pages. HEALTH RISKS OF SMOKELESS TOBACCO.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75127,"journal":{"name":"The Journal of the Oklahoma State Medical Association","volume":"108 11","pages":"518-20"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GUIDE TO QUITTING SMOKING. 戒烟指南。
The Journal of the Oklahoma State Medical Association Pub Date : 2015-11-01
{"title":"GUIDE TO QUITTING SMOKING.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75127,"journal":{"name":"The Journal of the Oklahoma State Medical Association","volume":"108 11","pages":"521-56"},"PeriodicalIF":0.0,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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