The journal of climate change and health最新文献

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Heatwave health risk index for Karnataka, India 印度卡纳塔克邦热浪健康风险指数
The journal of climate change and health Pub Date : 2025-03-01 DOI: 10.1016/j.joclim.2025.100428
Vidhatri Thakkar , Vidya Srinivas , Pradeep Marula Siddhappanavara , Tashina Madappa , Anushiya Jeganathan , Indu K. Murthy
{"title":"Heatwave health risk index for Karnataka, India","authors":"Vidhatri Thakkar ,&nbsp;Vidya Srinivas ,&nbsp;Pradeep Marula Siddhappanavara ,&nbsp;Tashina Madappa ,&nbsp;Anushiya Jeganathan ,&nbsp;Indu K. Murthy","doi":"10.1016/j.joclim.2025.100428","DOIUrl":"10.1016/j.joclim.2025.100428","url":null,"abstract":"<div><h3>Introduction</h3><div>With the rise in global temperatures due to climate change, heatwaves are predicted to become more frequent, prolonged, and intense. Safeguarding people's health, well-being, and quality of life from the effects of climate change and its extremes is now a priority for policymakers and international and national governments. High-risk areas, zones, districts, and communities must be recognized ahead of time to better guide planning and preparedness. This study focused on assessing the heatwave occurrence and developing a heatwave health risk index (HHRI) at the district level in Karnataka.</div></div><div><h3>Materials &amp; Method</h3><div>A comprehensive framework by the Intergovernmental Panel on Climate Change on a climate change risk assessment methodology incorporating hazard, exposure, and vulnerability was employed to develop the HHRI under the current climate change scenario. Among the crucial determinants influencing the HHRI, 11 indicators were selected, encompassing heatwave occurrence, diurnal temperature ranges, population density, outdoor labor population, population commuting on foot, number of medical institutions, green cover, elderly population, people with disabilities, multidimensional poverty index, and health index.</div></div><div><h3>Results</h3><div>The districts with higher hazard, exposure, and vulnerability were identified and mapped along with their risk driving key factors. Among the 31 districts examined in our study, Bidar, Kalaburagi, Gadag, and Dharwad districts were classified in the very high-risk category, whereas 9 were classified in the high-risk category.</div></div><div><h3>Conclusion</h3><div>The study findings on the variations in heatwave health risks among districts will enable policymakers to prioritize and execute targeted strategies to successfully reduce climate impacts.</div></div>","PeriodicalId":75054,"journal":{"name":"The journal of climate change and health","volume":"22 ","pages":"Article 100428"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adaptation and mitigation for the planetary health crisis: A scoping review from the perspective of primary health care providers 适应和缓解全球健康危机:从初级卫生保健提供者的角度进行范围审查
The journal of climate change and health Pub Date : 2025-03-01 DOI: 10.1016/j.joclim.2025.100440
Jacqueline Avanthay Strus , Joshitha Sankam , Samantha Green , Mckenzie Piper , Sabrina Richards , Kasey Knowles , Katie North , Leslie Solomonian
{"title":"Adaptation and mitigation for the planetary health crisis: A scoping review from the perspective of primary health care providers","authors":"Jacqueline Avanthay Strus ,&nbsp;Joshitha Sankam ,&nbsp;Samantha Green ,&nbsp;Mckenzie Piper ,&nbsp;Sabrina Richards ,&nbsp;Kasey Knowles ,&nbsp;Katie North ,&nbsp;Leslie Solomonian","doi":"10.1016/j.joclim.2025.100440","DOIUrl":"10.1016/j.joclim.2025.100440","url":null,"abstract":"<div><div>Climate-related adverse health outcomes are on the rise worldwide, and primary health care providers are at the forefront of the growing climate-health crisis. There is an urgent need for a codification of solutions and strategies for adaptation, resilience, and transformation in primary health care. This scoping review sought to answer the following research question: \"What strategies are being implemented across all forms of primary health care to adapt to and address the climate crisis?” After iterative axial coding of the 94 retained papers, 15 themes emerged: community engagement; reaching vulnerable populations; transdisciplinary and intersectoral collaboration; clinical strategies; research, surveillance; pluralism; patient education; continuing education and community of practice; benefits of nature; infrastructure resilience; advocacy; conservation; redefining health; provider wellbeing; and impact of health care. It behooves primary health care practitioners, especially those within dominant systems, to advocate strategies that promote health in all systems and policies. The planetary health crisis is a health crisis. It is urgent, it is human-created, and it can be mitigated.</div></div>","PeriodicalId":75054,"journal":{"name":"The journal of climate change and health","volume":"22 ","pages":"Article 100440"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143885977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring neighborhood racial and socioeconomic heterogeneity in the short-term effects of air pollution and extreme heat on medical emergencies 探索社区种族和社会经济异质性在空气污染和极端高温对医疗紧急情况的短期影响
The journal of climate change and health Pub Date : 2025-03-01 DOI: 10.1016/j.joclim.2025.100414
Karl Vachuska
{"title":"Exploring neighborhood racial and socioeconomic heterogeneity in the short-term effects of air pollution and extreme heat on medical emergencies","authors":"Karl Vachuska","doi":"10.1016/j.joclim.2025.100414","DOIUrl":"10.1016/j.joclim.2025.100414","url":null,"abstract":"<div><h3>Introduction</h3><div>As climate change continues to affect society, understanding how adverse climatic conditions impact different communities differently is essential to equitable climate change mitigation. While research has identified the potential for climate change to impact public health in terms of air quality and extreme heat, less research has explored <em>inequality</em> regarding how these events impact public health. This paper explores inequality in the effects of climatic events on short-term health based on air pollution and severe heat.</div></div><div><h3>Methods</h3><div>Using two-way fixed-effects models, racial and socioeconomic heterogeneity in the effects of air pollution and extreme heat on the incidence of medical emergencies are examined.</div></div><div><h3>Results</h3><div>Results suggest that poor air quality predominantly affects the incidence of medical emergencies in poor, non-White neighborhoods and has minimal effects in affluent White neighborhoods. Neighborhoods with more impoverished residents experience more medical emergencies on days with extreme heat.</div></div><div><h3>Conclusion</h3><div>Overall, the results suggest that extreme heat has substantial effects on medical emergencies, but there is little racial heterogeneity in these effects. Notably, the results provide little evidence of an interaction effect between poor air quality and extreme heat. The results show the need for climate change mitigation strategies that are equitable for all communities.</div></div>","PeriodicalId":75054,"journal":{"name":"The journal of climate change and health","volume":"22 ","pages":"Article 100414"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143628669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impacts of climate change on the global spread and habitat suitability of Coxiella burnetii: Future projections and public health implications 气候变化对伯氏杆菌全球传播和生境适宜性的影响:未来预测和公共卫生影响
The journal of climate change and health Pub Date : 2025-03-01 DOI: 10.1016/j.joclim.2025.100442
Abdallah Falah Mohammad Aldwekat , Niloufar Lorestani , Farzin Shabani
{"title":"Impacts of climate change on the global spread and habitat suitability of Coxiella burnetii: Future projections and public health implications","authors":"Abdallah Falah Mohammad Aldwekat ,&nbsp;Niloufar Lorestani ,&nbsp;Farzin Shabani","doi":"10.1016/j.joclim.2025.100442","DOIUrl":"10.1016/j.joclim.2025.100442","url":null,"abstract":"<div><h3>Introduction</h3><div><em>Coxiella burnetii</em>, an intracellular zoonotic bacterium, affectsing various livestock and wildlife species and poses significant risks to human health. This study aims to assess how climate change could impact the global distribution and habitat suitability of <em>Coxiella burnetii</em>, the pathogen responsible for Q fever.</div></div><div><h3>Materials and methods</h3><div>An ensemble species distribution modelling approach, integrating regression-based and machine-learning algorithms (GLM, GBM, RF, MaxEnt), was used to project habitat suitability (Current time and by 2050, 2070, and 2090). Climate variables were obtained from five global circulation models (GCMs) under two climate change scenarios (SSP2-4.5 and SSP5-8.5). The study evaluated the models’ performance using the area under the curve (AUC) and true skill statistics (TSS).</div></div><div><h3>Results</h3><div>Results show that under current climate conditions, <em>C. burnetii</em> is widespread across regions like North and South America, Europe, and parts of Africa, Asia, and Australia. Future projections indicate a northward shift in habitat suitability, especially under the severe SSP5-8.5 scenario, with significant expansions into Russia, northern Europe, and Canada. Conversely, regions in South America, Africa, and Australia may see declines in suitable habitats. By 2090, a 44.56 % (range: 33–57.9 %) across the models, increase in suitable habitat is predicted, accompanied by a 27.66 % (range: 22.4–31.7 %) loss of current habitats.</div></div><div><h3>Discussion</h3><div>Findings indicate that temperature seasonality and precipitation of the driest month are the most influential climatic variables shaping the distribution of <em>C. burnetii</em>. These results underscore the importance of climate variability in influencing the pathogen's global distribution and highlight the critical role of environmental factors in predicting future habitat shifts.</div></div><div><h3>Conclusion</h3><div>The study highlights the profound impact climate change could have on the global distribution of <em>C. burnetii</em>. It underscores the need for proactive public health strategies in emerging high-risk areas and emphasizes the importance of mitigating risks in regions experiencing habitat declines. These findings offer valuable insights for public health planning and livestock management under future climate scenarios. In interpreting these results, it is important to consider modelling uncertainties, including assumptions and data limitations.</div></div>","PeriodicalId":75054,"journal":{"name":"The journal of climate change and health","volume":"22 ","pages":"Article 100442"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of household-like waste discarded by health institutions in Chile: A descriptive study 智利卫生机构丢弃的家庭类废物分析:一项描述性研究
The journal of climate change and health Pub Date : 2025-03-01 DOI: 10.1016/j.joclim.2025.100437
Fernanda Olive , M.Bernardita Sanhueza , Andres Giglio , Andres Ferre
{"title":"Analysis of household-like waste discarded by health institutions in Chile: A descriptive study","authors":"Fernanda Olive ,&nbsp;M.Bernardita Sanhueza ,&nbsp;Andres Giglio ,&nbsp;Andres Ferre","doi":"10.1016/j.joclim.2025.100437","DOIUrl":"10.1016/j.joclim.2025.100437","url":null,"abstract":"<div><h3>Background</h3><div>Healthcare institutions generate significant amounts of household-like waste, with international evidence suggesting that up to 60 % is potentially recyclable. In Chile, comprehensive data on healthcare waste management and recycling practices are lacking.</div></div><div><h3>Objective</h3><div>To assess general waste management practices in Chilean healthcare institutions and evaluate the extent of implementation of waste recycling programs across the country.</div></div><div><h3>Methods</h3><div>We analyzed open data from the National Waste Generation Service (SINADER) for 2018–2022, focusing on healthcare institutions. Waste management practices were categorized as either disposal or valorization (recycling/pre-treatment). We evaluated the total waste volume, valorization rates, institutional characteristics, and geographical distribution of the waste management practices.</div></div><div><h3>Results</h3><div>Of the 4,586 registered healthcare institutions in Chile, 162 (3.6 %) reported waste data, generating 291,325 tons during the study period. Only 42 institutions reported recycling activities, with the highest valorization rate of 13.6 %. Public institutions comprised 38 % of the recycling centers, with 54 % located outside the Metropolitan Region. Paper and cardboard constituted 49 % of the recycled materials, followed by organic waste (22.7 %). The national healthcare waste valorization rate increased from 0.92 % to 2.14 % between 2018 and 2022.</div></div><div><h3>Conclusions</h3><div>This first comprehensive analysis revealed a substantial recycling gap in Chilean healthcare institutions, with current practices falling significantly below international benchmarks. The low reporting rate (3.6 %) and limited valorization highlight the urgent need for improved waste reporting systems and the implementation of comprehensive recycling programs. Achieving Chile's 2040 environmental goals will require coordinated efforts to increase healthcare waste recycling rates by at least five-fold to meet international standards.</div></div>","PeriodicalId":75054,"journal":{"name":"The journal of climate change and health","volume":"22 ","pages":"Article 100437"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integration and use of climate data by the national health system in Mozambique 莫桑比克国家卫生系统对气候数据的整合和使用
The journal of climate change and health Pub Date : 2025-03-01 DOI: 10.1016/j.joclim.2024.100368
Judite Pinto , Nelson Cossa , Mara Ferrari , Patricia S. Coffey , Melanie Picolo , Tatiana Marrufo , Ana Paula Cardoso
{"title":"Integration and use of climate data by the national health system in Mozambique","authors":"Judite Pinto ,&nbsp;Nelson Cossa ,&nbsp;Mara Ferrari ,&nbsp;Patricia S. Coffey ,&nbsp;Melanie Picolo ,&nbsp;Tatiana Marrufo ,&nbsp;Ana Paula Cardoso","doi":"10.1016/j.joclim.2024.100368","DOIUrl":"10.1016/j.joclim.2024.100368","url":null,"abstract":"<div><h3>Introduction</h3><div>Mozambique is increasingly affected by extreme weather events and associated infectious disease outbreaks, highlighting a significant gap in knowledge on use of data to better inform health system preparedness and response.</div></div><div><h3>Methods</h3><div>In this qualitative study, we collected data from 29 key informants using customized semi-structured questionnaires. Data were then triangulated and analyzed using content and thematic methods.</div></div><div><h3>Results</h3><div>The National Institute of Meteorology is primarily responsible for producing and supplying weather data to the national health system (NHS). NHS has access only to weather data, and there is no specific platform or system for integrating weather or climate data and health data. Other notable barriers to sharing and using climate data include poor geographical coverage of the meteorological network and lack of systematic records on the impact of extreme events. Facilitating factors include multiple policies that mention the link between climate change and health, and the existence of health data management platforms and an early warning system piloted by the National Institute of Health.</div></div><div><h3>Conclusion</h3><div>Ongoing work to develop a health sector climate change adaptation plan and revitalize the Public Health Emergency Operations Center could be key to accelerating efforts to improve climate data use to inform infectious disease outbreak preparedness and response. Results from piloting of the early warning system could be used to advocate for climate data integration into the NHS to help in identifying the impact of climate change on health and designing effective plans to address climate-related infectious disease outbreaks.</div></div>","PeriodicalId":75054,"journal":{"name":"The journal of climate change and health","volume":"22 ","pages":"Article 100368"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143512653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Towards youth-inclusive strategies for research on climate change and health in sub-saharan Africa 制定撒哈拉以南非洲气候变化与健康研究的青年包容性战略
The journal of climate change and health Pub Date : 2025-03-01 DOI: 10.1016/j.joclim.2025.100418
Adelaide M Lusambili , Kizito L Muchanga , Laurie Maria Vusolo , Constance S Shumba
{"title":"Towards youth-inclusive strategies for research on climate change and health in sub-saharan Africa","authors":"Adelaide M Lusambili ,&nbsp;Kizito L Muchanga ,&nbsp;Laurie Maria Vusolo ,&nbsp;Constance S Shumba","doi":"10.1016/j.joclim.2025.100418","DOIUrl":"10.1016/j.joclim.2025.100418","url":null,"abstract":"<div><div>Globally, young people are effecting significant changes in the field of climate change through various means, such as advocacy, education and awareness campaigns, litigation, innovative solutions, and volunteering. These youth-led initiatives are essential, considering that they will face the long-term health effects of climate change. The need to address disparities in climate and health-related research, policy, and program responses in sub-Saharan Africa (SSA) has never been greater, considering the increasingly pronounced effects of climate change on human health. Within the African continent, where research, policies and programs are predominantly shaped by older people, the inclusion of youth is vital to contribute effectively to the discourse on climate change. In this short communication, we reflect on the limited representation of young people as researchers within the African academy studying the links between climate change and health. We provide a rationale emphasizing the urgent need to build a robust community of researchers that encompasses youth. Our argument advocates for gender-responsive investments in training young researchers in climate change and health to deepen their understanding and address the disproportionate impacts on vulnerable populations. We propose strategies to enhance their meaningful involvement in research and knowledge production in these fields.</div></div>","PeriodicalId":75054,"journal":{"name":"The journal of climate change and health","volume":"22 ","pages":"Article 100418"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143724742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“Impacts of extreme heat on mental health: Systematic review and qualitative investigation of the underpinning mechanisms” 极端高温对心理健康的影响:基础机制的系统回顾和定性调查
The journal of climate change and health Pub Date : 2025-03-01 DOI: 10.1016/j.joclim.2025.100446
Lea Baecker, Udita Iyengar, Maria Chiara Del Piccolo, Andrea Mechelli
{"title":"“Impacts of extreme heat on mental health: Systematic review and qualitative investigation of the underpinning mechanisms”","authors":"Lea Baecker,&nbsp;Udita Iyengar,&nbsp;Maria Chiara Del Piccolo,&nbsp;Andrea Mechelli","doi":"10.1016/j.joclim.2025.100446","DOIUrl":"10.1016/j.joclim.2025.100446","url":null,"abstract":"<div><h3>Introduction</h3><div>We are living on an increasingly hot planet, with negative impacts for the mental health of affected individuals and communities. A better understanding of the physiological, psychological, behavioral, and social mechanisms which underlie these impacts could inform the development of effective interventions. Here, we conducted a mixed-method study combining a systematic review and qualitative investigation to explore these mechanisms.</div></div><div><h3>Methods</h3><div>Adhering to the PRISMA guidelines, we searched PubMed for publications related to extreme heat, mental health, and mechanisms. Peer-reviewed studies reporting original data on mechanisms explaining the impact of extreme heat on mental health were included. In addition, we conducted six focus groups on extreme heat and mental health with a total of 33 participants (<em>n</em> = 21 people with lived experience, <em>n</em> = 12 healthcare professionals). Transcripts were analyzed using thematic content analysis.</div></div><div><h3>Results</h3><div>Out of 241 articles identified by the literature search, four studies were eligible for inclusion. These provided limited evidence for activation of the hypothalamic-pituitary-adrenal axis, increased psychological stress, reduced exercise, and sleep disruption. The analysis of the focus groups expanded these findings by highlighting additional themes related to physical (e.g., fatigue), psychological (e.g., health anxiety), behavioral (e.g., reduced access to usual coping strategies), and social mechanisms (e.g., social isolation).</div></div><div><h3>Conclusion</h3><div>There is a dearth of reliable data on the mechanisms underpinning the impacts of extreme heat on mental health. Our mixed-method approach identified a range of promising physiological, psychological, behavioral, and social mechanisms, and highlights the importance of including people with lived experience in the conversation.</div></div>","PeriodicalId":75054,"journal":{"name":"The journal of climate change and health","volume":"22 ","pages":"Article 100446"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143816245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary on: Wong YL, Wong SW, Ting DSJ, Muralidhar A, Sen S, Schaff O, et al. Impacts of climate change on ocular health: A scoping review. J Clim Chang Heal. 2024 Jan 1;15:100296. doi: 10.1016/j.joclim.2023.100296. 评论:王玉玲,王士文,丁德杰,Muralidhar A, Sen S, Schaff O,等。气候变化对眼健康的影响:范围综述。[J] .中国科学院学报(自然科学版);doi: 10.1016 / j.joclim.2023.100296。
The journal of climate change and health Pub Date : 2025-03-01 DOI: 10.1016/j.joclim.2025.100441
Seth Dhillon , Baljean Dhillon
{"title":"Commentary on: Wong YL, Wong SW, Ting DSJ, Muralidhar A, Sen S, Schaff O, et al. Impacts of climate change on ocular health: A scoping review. J Clim Chang Heal. 2024 Jan 1;15:100296. doi: 10.1016/j.joclim.2023.100296.","authors":"Seth Dhillon ,&nbsp;Baljean Dhillon","doi":"10.1016/j.joclim.2025.100441","DOIUrl":"10.1016/j.joclim.2025.100441","url":null,"abstract":"","PeriodicalId":75054,"journal":{"name":"The journal of climate change and health","volume":"22 ","pages":"Article 100441"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of climate change on adipose-derived stem cells: A molecular and histological study 气候变化对脂肪干细胞的影响:一项分子和组织学研究
The journal of climate change and health Pub Date : 2025-03-01 DOI: 10.1016/j.joclim.2024.100367
Saeed Motesaddi Zarandi , Rasoul Yarahmadi , Rasul Nasiri , Mohammad Bayat , Hossein Nasiri , Abdollah Amini , Mohammad Esmaeil Motlagh , Hassan Rasoulzadeh
{"title":"Impact of climate change on adipose-derived stem cells: A molecular and histological study","authors":"Saeed Motesaddi Zarandi ,&nbsp;Rasoul Yarahmadi ,&nbsp;Rasul Nasiri ,&nbsp;Mohammad Bayat ,&nbsp;Hossein Nasiri ,&nbsp;Abdollah Amini ,&nbsp;Mohammad Esmaeil Motlagh ,&nbsp;Hassan Rasoulzadeh","doi":"10.1016/j.joclim.2024.100367","DOIUrl":"10.1016/j.joclim.2024.100367","url":null,"abstract":"<div><h3>Background</h3><div>Climate change, particularly temperature and humidity fluctuations, can affect biological systems. This study specifically investigates the impact of these two key aspects of climate change on adipose-derived stem cells (ADSCs) as a pilot study and starting point for further examinations into the biological effects of climate change-associated conditions.</div></div><div><h3>Methods</h3><div>One-month-old male rats were kept for 4 months (equal to a 10-year climatic period) in 4 groups and exposed to conditions based on climatic data from Tehran's synoptic stations. Rats in the control group were exposed to conditions based on climatic data from 1991, and groups 2–4 were exposed to conditions based on climatic data from 1991 to 2000, 2001–2010, and 2011–2020, respectively. Monthly temperature, humidity, and day/night cycle averages were selected for animal exposure. After exposure, fat-derived stem cells were taken from each subject and assays assessing reactive oxygen species (ROS), cell viability and proliferation, and apoptosis were performed.</div></div><div><h3>Results</h3><div>From 1991 to 2020, Tehran experienced an average temperature increase of 1.5 °C and a 15 % decrease in average humidity, conditions which when replicated in rodent models were associated with increased rates of ROS and caspase-3 expression, a reduction in Ki-67 antigen expression and in the duration of the life of cells, and an increase in the rate of apoptosis, such that apoptosis in ADSCs reached 25.51 %.</div></div><div><h3>Conclusion</h3><div>The study demonstrates that environmental conditions similar to those from climate change are associated with significant changes in ADSCs and emphasizes the need for further research to understand their impact on health.</div></div>","PeriodicalId":75054,"journal":{"name":"The journal of climate change and health","volume":"22 ","pages":"Article 100367"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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