The Journal of biocommunication最新文献

{"title":"AMI Salon Winners - 2019: Milwaukee AMI Annual Meeting.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This JBC Gallery features the Salon award winners from AMI's 2019 annual meeting held in Milwaukee, Wisconsin. The annual meeting Salon exhibition represents the AMI's visual media competition showcasing some of the finest medical illustration, animation, graphics, and media in the life sciences and medicine.</p>","PeriodicalId":75049,"journal":{"name":"The Journal of biocommunication","volume":"43 2","pages":"e24"},"PeriodicalIF":0.0,"publicationDate":"2019-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139208/pdf/jbc-43-2-e24.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40503648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BCA BIOIMAGES Winners - 2019: Asilomar BCA Annual Meeting.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This JBC Gallery features the BioImages award winners from BIOCOMM 2019 held at Asilomar State Beach & Conference Center in Pacific Grove, California. BioImages represents the BCA's annual visual media competition that showcases the finest still imagery, graphics, and motion media in the life sciences and medicine.</p>","PeriodicalId":75049,"journal":{"name":"The Journal of biocommunication","volume":"43 2","pages":"e25"},"PeriodicalIF":0.0,"publicationDate":"2019-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9139007/pdf/jbc-43-2-e25.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40503646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Multimedia Principles to Reduce Visual Complexity of Transcriptional Regulation in Cancer","authors":"Dani E Bergey, Kevin Brennan, D. Milkowski, Christine D. Young","doi":"10.5210/jbc.v43i2.10228","DOIUrl":"https://doi.org/10.5210/jbc.v43i2.10228","url":null,"abstract":"Environmental factors can regulate gene expression without changing the genetic code itself, a process called epigenetics. One currently active area of genetic and epigenetic research is into the regulation of a tumor-inducing gene called Mylocytomatosis, or MYC, which is involved in many types of cancer. As genetic discoveries, such as the regulation of MYC, are generating more interest from the medical community and the public, creating effective visuals is of increasing importance. However, research studies on the general public's understanding of genetics have demonstrated a poor grasp of genetic concepts - a finding that also appears in similar studies of undergraduate genetics students, medical students, and practicing physicians. Fortunately, visual learning studies and multimedia design principles have established methods for improving comprehension of biomedical topics. Animation, in particular, has the benefit of pairing narration and dynamic visuals, which, when used together, benefit long-term memory more than the use of static images. Here, we employ visual design strategies (including content mapping, storyboarding, and user studies), multimedia learning principles, and 3D molecular animation to successfully improve the understanding of a complex genetic topic to an audience with a wide range of background knowledge. This study presents the first and most accurate animation of the complex interactions of transcription initiation and elongation on a molecular scale. The animation includes the initiation complex, the transcription elongation complex, MYC, Pol II, and the assortment of transcription factors that assist in modulating the rate of elongation of Pol II. The resulting product is a three-minute animation which uses audio, visuals, and a deep understanding of multimedia principles to significantly increase individuals' prior knowledge of a complex topic in molecular genetics.","PeriodicalId":75049,"journal":{"name":"The Journal of biocommunication","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81955237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Expertise on Perception and Understanding on Viewing a Molecular Animation of the Lung Endothelial Surface Layer and its Role in Inflammation","authors":"Chinami Michaels, Kevin Brennan, Leah A. Lebowicz, R. Dull, Christine D. Young","doi":"10.5210/jbc.v43i2.10227","DOIUrl":"https://doi.org/10.5210/jbc.v43i2.10227","url":null,"abstract":"A study of the effect of expertise on the perception and understanding of a 3D biomedical animation and the ability of a 3D animation of the lung endothelial surface layer to generate understanding of, and interest in, the lung endothelial surface layer was carried out using a mix of quantitative and qualitative approaches. The animation was tested using eye-tracking with five lung trauma researchers who were experts on the animation's topic, the lung endothelial surface layer, and with 15 biomedical visualization graduate students who lacked prior knowledge of the structure and science of the lung endothelial surface layer. Information on demographics, knowledge gain on the lung endothelial surface layer, eye-tracking recordings, cued-retrospective reports, and written open-ended feedback were collected from both groups. The eye-tracking results, cued-retrospective audio recordings, and surveys between the groups of experts and novices showed expertise influenced perception and understanding of the animation of the lung ESL. The group with high expertise on the lung endothelial surface layer rated the animation as very engaging. They gained knowledge on the lung endothelial surface layer from the animation and would recommend the animation to their colleagues as an introduction to their research. Their eye-tracking results and cued-retrospective reporting showed greater attention paid to areas of high scientific relevancy in the animation. They also showed a viewing pattern of switching to one modality (audio or visual) to seek new information when shown familiar representations similar to schematics in the science literature. The group without prior knowledge of the lung endothelial surface layer focus also gained in knowledge of the lung endothelial surface layer after watching the animation. They paid more attention to aspects of how the animation was created and less to the scientifically relevant areas. They rated the animation on average as moderately engaging. These results demonstrate how important designing for a target audience is in order to maximize multimedia's potential to fully engage and generate interest, as prior expertise greatly influences how an audience perceives and understands biomedical animations.","PeriodicalId":75049,"journal":{"name":"The Journal of biocommunication","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84133352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative Modeling and Visualization of Exosomes.","authors":"Julia Jiménez, Ludovic Autin, Inmaculada Ibáñez de Cáceres, David S Goodsell","doi":"10.5210/jbc.v43i2.10331","DOIUrl":"10.5210/jbc.v43i2.10331","url":null,"abstract":"<p><p>Information from proteomics, microscopy, and structural biology are integrated to create structural models of exosomes, small vesicles released from cells. Three visualization methods are employed and compared: 2D painting of a cross section using traditional media, manual creation of a cross section using the mesoscale 2.5D digital painting software cellPAINT, and generation of a 3D atomic model using the mesoscale modeling program cellPACK.</p>","PeriodicalId":75049,"journal":{"name":"The Journal of biocommunication","volume":"43 2","pages":"e10"},"PeriodicalIF":0.0,"publicationDate":"2019-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/45/00/jbc-43-2-e10.PMC9139774.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40503649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Drawing as an Active Engagement Tool to Empower Learners and Promote Teaching of Health Topics","authors":"Arianna Selagea, Leah A. Lebowicz, Samantha Bond, John Daugherty","doi":"10.5210/jbc.v43i2.10172","DOIUrl":"https://doi.org/10.5210/jbc.v43i2.10172","url":null,"abstract":"Particular barriers to health care and the lack of proper health education causes many community members of Lagos, Nigeria to suffer from diseases because they do not know how to prevent their development, contraction and/or spread. Hypertension is one such disease that may remain undetected until it is too late, since many community members cannot correctly define blood pressure, its causes, and the impact certain values have upon health. By educating the community of Lagos of the importance of taking their blood pressure and interpreting values correctly, members are encouraged to seek proper help to make the disease's management more successful. At the basis of understanding hypertension is knowing the anatomy, which can be learned most effectively using an active engagement method, like drawing. The target audience is two fold: Community Health Educators (CHEs), who are volunteers trained through Northwestern's current Access to Health initiative, and low-literacy community members who lack access to health care/ information and are educated by the CHEs. Active engagement can help improve learning and retention of information by the CHEs and similar audiences who intend to teach others. Through an active engagement such as drawing, the CHEs can be educated and empowered to teach low-literacy community members health topics. Drawing can be applied in all settings and has been found to increase knowledge gain, retention, and problem-solving skills. Viewing and following the process of drawing is beneficial in understanding how structures are related and how they function.5 Providing a partially drawn base image to complete also aids learning by reducing cognitive load and increasing accuracy of the final image. By incorporating a warm-up exercise and simple drawing steps in a video, CHEs and similar populations can learn how to draw health concepts and become empowered to educate lower-literacy community members using drawing at any place and time of need.","PeriodicalId":75049,"journal":{"name":"The Journal of biocommunication","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80507623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Visual Scientific Data on Comprehension and Perception of Educational Animations for Biomedical Researchers","authors":"Isabel Romero Calvo, Leah A. Lebowicz, Christine D. Young, Kevin Brennan","doi":"10.5210/jbc.v43i2.10223","DOIUrl":"https://doi.org/10.5210/jbc.v43i2.10223","url":null,"abstract":"Due to the rapid evolution of biomedical research, it is crucial to effectively communicate new technological advances in topics such as organoid models in cancer therapeutics to help improve health outcomes. Visual communication, including animation, has been shown to improve cognition and understanding of complex biological processes. However, there is contradictory information about the amount of detail that should be used for effective communication when utilizing animation. Although it is known that the inclusion of detailed references increases the scientific community's perceived credibility of the visualization, the effect of including visual scientific data is unknown. This research examines the impact of including visual scientific data in an educational animation by analyzing biomedical researchers' perception of credibility and learning outcomes with respect to cancer organoid research.","PeriodicalId":75049,"journal":{"name":"The Journal of biocommunication","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75541538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autopsy Brain Removal Training Using Virtual Reality Simulation","authors":"I. Choi","doi":"10.5210/jbc.v43i2.10225","DOIUrl":"https://doi.org/10.5210/jbc.v43i2.10225","url":null,"abstract":"Hospital autopsy is the only method of confirming diagnoses for neurodegenerative disease such as Alzheimer's and Lewy body disease, despite advanced diagnostic technologies. However, the number of hospital autopsies has steadily declined, due to changes in hospital accreditation requirements, lack of reimbursement, and other factors. Consequently, it is challenging to train autopsy assistants, pathology residents and neuropathology fellows to become competent in evisceration and dissection techniques, as there are few opportunities to observe and perform hospital autopsies. The procedure for autopsy brain removal is particularly challenging because: (i) incorrect cutting planes and depth of cut during opening of the cranium can lead to inadequate exposure of, or damage to, brain tissue, and (ii) there may be initial hesitation to perform the procedure due to proximity to the face. These challenges are compounded because current teaching resources are limited to drawings (which lack key spatial and volumetric cues) and photographs (which provide only a single view, and may have superfluous information); no physical practice of the procedure is involved. To address this deficit, a virtual reality (VR) simulation application was developed to teach proper methodology in performing steps of the autopsy brain removal, and as a proof-of-concept for a complete hospital autopsy VR simulation. The simulation provides an immersive VR interactive experience within an Oculus Rift platform. It uses realistic virtual patient models created from surface 3D scans of a real person, data-driven 3D models of anatomy, sound effects, and haptic responses within a VR autopsy suite. The simulation also features real-time visual feedback and evaluation of user performance, to assist improvement of skills and knowledge during the step of opening the cranium with an oscillating saw. This thesis documents the process of developing the VR simulation, in particular the creation and use of i) 3D models of patient, cranium and brain, ii) interactions between instruments and patient in VR, iii) in-game feedback: visual, sound and haptic, and iv) user interface (UI) interaction in VR.","PeriodicalId":75049,"journal":{"name":"The Journal of biocommunication","volume":"112 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84918439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Publisher's Comment.","authors":"Gary W Schnitz","doi":"10.5210/jbc.v43i2.10169","DOIUrl":"https://doi.org/10.5210/jbc.v43i2.10169","url":null,"abstract":"<p><p>Welcome to the Journal of Biocommunication issue 43-2. The issue represents our second issue of 2019 and our seventh issue designed for our new mixed publishing format that offers our authors traditional publishing as well as open access options. Our Journal is dedicated to the dissemination of high-quality research, and we accept manuscripts, which are of interest to the broader bioscience community. We welcome authors reporting on their high-impact discoveries, cutting-edge research, and new imaging methodologies. Our professional organizations and the Journal are critical for generating open access content of scholarly, intellectual, and creative merit.</p>","PeriodicalId":75049,"journal":{"name":"The Journal of biocommunication","volume":"43 2","pages":"e8"},"PeriodicalIF":0.0,"publicationDate":"2019-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/da/07/jbc-43-2-e8.PMC9138818.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40503644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Professional Clinical Photography to Assist Patients with Pectus Carinatum.","authors":"John A Yeats","doi":"10.5210/jbc.v43i2.10230","DOIUrl":"https://doi.org/10.5210/jbc.v43i2.10230","url":null,"abstract":"<p><p>A photographic clinical role has been realized in our institution in the care of patients with Pectus Carinatum. A series of clinical photographs along with 3D imaging are now presented by our photographers to each patient in clinic to demonstrate changes over time in the size and shape of their chest wall defects associated with this condition. This interaction has increased patient compliance for treatment and subsequently reinforces the relevance and importance of clinical photographers in patient care.</p>","PeriodicalId":75049,"journal":{"name":"The Journal of biocommunication","volume":"43 2","pages":"e12"},"PeriodicalIF":0.0,"publicationDate":"2019-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/82/3d/jbc-43-2-e12.PMC9140316.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40503645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}