AIDS最新文献

{"title":"Analysis of HIV transmission characteristics and intervention effects in Guangxi based on molecular networks.","authors":"Xianwu Pang, Jie Ma, Qin He, Kailing Tang, Jinghua Huang, Ningye Fang, Haomin Xie, Guanghua Lan, Shujia Liang","doi":"10.1097/QAD.0000000000004123","DOIUrl":"10.1097/QAD.0000000000004123","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluates changes in HIV transmission and the effectiveness of interventions after two rounds of the Guangxi AIDS Conquering Project (GACP) in Guangxi, China.</p><p><strong>Methods: </strong>Samples and epidemiological data from newly diagnosed people with HIV (PWH) between 2014 and 2020 were analyzed. Molecular networks were constructed using nested PCR amplification and sequencing of the pol region, and multivariable logistic regression identified factors associated with clustering and high-degree nodes.</p><p><strong>Results: </strong>A total of 4227 valid sequences (73.12% inclusion rate) were analyzed. Demographic changes included an increasing proportion of individuals aged at least 50 years (49.66%), with lower education (50.51%), peasants (76.82%), and heterosexual transmission (90.29%). The overall clustering rate was 86.89%, with higher clustering among individuals aged at least 50 years (92.57%), those with primary school or below (89.09%), peasants (88.11%), and CRF08_BC infections (91.48%). Annual declines in cluster growth rate and clustering rates were observed, particularly among individuals aged less than 30 years, college graduates, MSM, and people who inject drugs (PWID). Key transmission hotspots were identified in Lingshan, particularly among older, less-educated individuals, and peasants. Factors associated with clustering included being male (aOR: 1.27), aged at least 50 years (aOR: 3.84), and infected with CRF08_BC (aOR: 2.12). From 2017 to 2020, the risk of clustering and high-degree nodes was lower compared to 2014-2016, suggesting the effectiveness of interventions.</p><p><strong>Conclusion: </strong>Interventions in Guangxi effectively reduced HIV transmission among younger, high-degree populations. However, older, less-educated individuals remain at high risk, necessitating targeted strategies to address their specific needs and achieve better HIV control.</p>","PeriodicalId":7502,"journal":{"name":"AIDS","volume":" ","pages":"719-727"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepcidin modifies the relationship between anemia, erythrocyte indices, and neurocognitive performance in virally suppressed people with HIV.","authors":"Azin Tavasoli, Oluwakemi K Okwuegbuna, Bin Tang, Jennifer E Iudicello, Asha R Kallianpur, Ronald J Ellis, Scott L Letendre","doi":"10.1097/QAD.0000000000004110","DOIUrl":"10.1097/QAD.0000000000004110","url":null,"abstract":"<p><strong>Objective: </strong>Neurocognitive impairment in people with HIV (PWH) is associated with erythrocyte indices, which may serve as indicators of iron metabolism, inflammation, and related factors. Erythropoiesis requires iron, regulated by a multifaceted system of peptide hormones, including hepcidin. This study postulated that hepcidin might modify the relationship between erythrocyte indices and neurocognitive performance in PWH.</p><p><strong>Methods: </strong>Plasma hepcidin and erythrocyte indices were quantified in 88 virally suppressed PWH who underwent comprehensive neurocognitive assessments. Global neurocognitive performance was summarized by global T -scores. Associations of global T -scores with anemia and erythrocyte indices were determined in univariable analyses. To examine the influence of hepcidin on the relationship between neurocognitive performance and erythrocyte indices, we evaluated interactions between these covariates in relation to global T -scores and then performed stratified analyses.</p><p><strong>Results: </strong>In multivariable analyses, hepcidin detectability interacted with age ( P  = 0.007) and mean corpuscular volume (MCV; P  = 0.031) in relation to the global T -score. Interactions between anemia and erythrocyte indices on global T -scores were significant (anemia × MCV, P  = 0.008; anemia × MCH, P  = 0.011). Stratified analyses identified that lower global T -scores were associated with older age ( P  = 0.001) and higher MCV ( P  = 0.0046) and mean corpuscular hemoglobin (MCH, P  = 0.026) only when hepcidin was undetectable. Among the anemic, worse global T -score was associated with higher MCV ( P  = 0.001) and MCH ( P  = 0.002).</p><p><strong>Conclusion: </strong>Findings suggest that iron-related factors (hepcidin, anemia, MCV, MCH) and age influence neurocognitive health. This cross-sectional study underscores hepcidin as an effect modifier in the associations of erythrocyte indices, anemia, and age with neurocognitive function in PWH.</p>","PeriodicalId":7502,"journal":{"name":"AIDS","volume":" ","pages":"658-666"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term non-progression in children with HIV: estimates from international cohort data.","authors":"Charlotte Jackson, Siobhan Crichton, Ali Judd, Alasdair Bamford, Philip Goulder, Nigel Klein, Laura Marques, Paolo Paioni, Andrew Riordan, Vana Spoulou, Vinicius Adriano Vieira, Santa Ansone, Elena Chiappini, Sophie Le Coeur, Luminita Ene, Luisa Galli, Carlo Giaquinto, Tessa Goetghebuer, Claudia Fortuny, Suparat Kanjanavanit, Magda Marczynska, Marisa Navarro, Lars Naver, Nicole Ngo-Giang-Huong, Yulia K Plotnikova, Aleksey A Plynskey, Jose Tomas Ramos, Irina Raus, Vladimir Y Rozenberg, Anna V Samarina, Elisabeth H Schölvinck, Natalia Vasylenko, Alla Volokha, Intira Jeannie Collins, Ruth Goodall","doi":"10.1097/QAD.0000000000004136","DOIUrl":"10.1097/QAD.0000000000004136","url":null,"abstract":"<p><strong>Objectives: </strong>To estimate the probability of long-term nonprogression (LTNP) in the absence of antiretroviral treatment (ART) in children with perinatally acquired HIV, and the impact of LTNP definitions on these estimates.</p><p><strong>Design: </strong>Analysis of longitudinal routine care data (follow-up to 2016) collected through a collaboration of cohorts of children in routine HIV care across Europe and Thailand.</p><p><strong>Methods: </strong>LTNP was defined as reaching age 8 years without disease progression (defined as an AIDS diagnosis or immunosuppression based on WHO immunosuppression-for-age thresholds, age-adjusted CD4 +z -scores or CD4 + counts). ART initiation was treated as a competing risk (children initiating ART before age 8 were not considered to have LTNP). We included children born domestically in six national HIV cohorts ( n  = 2481). Additional analyses included domestic-born children enrolled in national cohorts in infancy (aged <12 months, n  = 1144, six cohorts), or all domestic-born children in national and nonnational cohorts ( n  = 4542, 18 cohorts). Results were stratified by birth year.</p><p><strong>Results: </strong>Among children born domestically in national cohorts in 2004-2007, the probability [95% confidence interval (CI)] of LTNP at age 8 years was 10% (6-15%) based on WHO immunosuppression-for-age criteria. This was lower for children born earlier when ART use was less frequent. Results were similar using other immunosuppression thresholds. Estimates were lower when restricted to domestic-born children in national cohorts enrolled in infancy, and higher when including all domestic-born children.</p><p><strong>Conclusion: </strong>Up to 10% of children born during 2004-2007 had LTNP at age 8. Our findings may help identify participants with LTNP for research into posttreatment control and HIV cure.</p>","PeriodicalId":7502,"journal":{"name":"AIDS","volume":" ","pages":"746-759"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143254017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What happened with preexposure prophylaxis uptake among female sex workers in Zimbabwe? Implications for future prevention programmes.","authors":"Joanna Busza, Fortunate Machingura, Tatenda Kujeke, Memory Makamba, Gracious Madimutsa Jumali, Primrose Matambanadzo, Sungai Chabata, Frances Mary Cowan","doi":"10.1097/QAD.0000000000004109","DOIUrl":"https://doi.org/10.1097/QAD.0000000000004109","url":null,"abstract":"","PeriodicalId":7502,"journal":{"name":"AIDS","volume":"39 6","pages":"771-773"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The future of HIV: challenges in meeting the 2030 Ending the HIV Epidemic in the US (EHE) reduction goal.","authors":"Amanda M Bleichrodt, Justin T Okano, Isaac C H Fung, Gerardo Chowell, Sally Blower","doi":"10.1097/QAD.0000000000004122","DOIUrl":"10.1097/QAD.0000000000004122","url":null,"abstract":"<p><strong>Objectives: </strong>To predict the burden of HIV in the United States (US) nationally and by region, transmission type, and race/ethnicity through 2030.</p><p><strong>Methods: </strong>Using publicly available data from the CDC NCHHSTP AtlasPlus dashboard, we generated 11-year prospective forecasts of incident HIV diagnoses nationally and by region (South, non-South), race/ethnicity (White, Hispanic/Latino, Black/African American), and transmission type (Injection-Drug Use, Male-to-Male Sexual Contact (MMSC), and Heterosexual Contact (HSC)). We employed weighted (W) and unweighted (UW) n -sub-epidemic ensemble models, calibrated using 12 years of historical data (2008-2019), and forecasted trends for 2020-2030. We compared results to identify persistent, concerning trends across models.</p><p><strong>Results: </strong>We projected substantial decreases in incident HIV diagnoses nationally (W: 27.9%, UW: 21.9%), and in the South (W:18.0%, UW: 9.2%) and non-South (W: 21.2%, UW: 19.5%) from 2019 to 2030. However, concerning nondecreasing trends were observed nationally in key sub-populations during this period: Hispanic/Latino persons (W: 1.4%, UW: 2.6%), Hispanic/Latino MMSC (W: 9.0%, UW: 9.9%), people who inject drugs (PWID) (W: 25.6%, UW: 9.2%), and White PWID (W: 3.5%, UW: 44.9%). The rising trends among Hispanic/Latino MMSC and overall PWID were consistent across the South and non-South regions.</p><p><strong>Conclusions: </strong>Although the forecasted national-level decrease in the number of incident HIV diagnoses is encouraging, the US is unlikely to achieve the Ending the HIV Epidemic in the US goal of a 90% reduction in HIV incidence by 2030. Additionally, the observed increases among specific subpopulations highlight the importance of a targeted and equitable approach to effectively combat HIV in the US.</p>","PeriodicalId":7502,"journal":{"name":"AIDS","volume":" ","pages":"708-718"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11968241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and incidence of human papilloma virus-related dysplasia of oropharyngeal, cervical, and anal mucosae in Spanish people with HIV.","authors":"Carmen Hidalgo-Tenorio, Inmaculada Calle-Gómez, Raquel Moya, Mohamed Omar, Javier Lopez-Hidalgo, Javier Rodriguez-Granges, Leopoldo Muñoz, Carmen García-Martinez","doi":"10.1097/QAD.0000000000004113","DOIUrl":"10.1097/QAD.0000000000004113","url":null,"abstract":"<p><strong>Background: </strong>Objectives were to determine the prevalence/incidence of HPV-related dysplasia and clearance/acquisition rates of high-risk HPV (HR-HPV) genotypes in genital mucosa of women with HIV (WWHIV) and oropharyngeal and anal mucosa of people with HIV (PWH) and to evaluate factors related to HR-HPV infection in oropharyngeal mucosa at 12-months.</p><p><strong>Material and methods: </strong>Prospective, longitudinal study with 12-month follow-up, enrolled PWH between December 2022 and April 2023. At baseline and 12 months, HIV-related clinical and analytical variables were recorded, oropharyngeal mucosa exudates were taken for PCR studies for human papilloma virus (HPV) and other sexually transmitted infections, whereas anal and female genital samples were self-sampled for HPV detection and genotyping by PCR and thin-layer cytology.</p><p><strong>Results: </strong>Two hundred and seventy-six PWH with mean age of 45.3 years, 79% men, 24.3% with history of AIDS, 100% under antiretroviral therapy (ART), and 30.1% with completed HPV vaccination. HPV infection prevalence in oropharyngeal mucosa was 11.6% at baseline, most frequently by genotype 16 (2.2%), without dysplasia. No oropharyngeal dysplasia was observed at 12 months, and HR-HPV clearance and acquisition rates were 5.5 and 4.4%, respectively. Incidence of anal high grade squamous intraepithelial lesion (HSIL) was 1811.6 cases × 100 000 people-year, and HR-HPV clearance and acquisition rates were 16.2 and 25.6%, respectively. Incidence of CIN2/CIN3 or cervical cancer was zero, and HR-HPV clearance and acquisition rates were 11.3 and 7.5%. HIV-RNA viral load less than 50 copies/ml protected against HPV infection in oropharyngeal mucosa [97.2 vs. 87%, hazard ratio 0.044; 95% confidence interval (95% CI 0.042 - 0.956)].</p><p><strong>Conclusion: </strong>Among PWH, HSIL incidence and HR-HPV acquisition rate are higher in anal versus oropharyngeal and genital mucosae. Nondetectability protects against oropharyngeal HPV infection.</p>","PeriodicalId":7502,"journal":{"name":"AIDS","volume":" ","pages":"649-657"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"'Suffer the little children …' Lessons from the EPPICC study, concern about the future, and a call to action.","authors":"Dean L Winslow","doi":"10.1097/QAD.0000000000004164","DOIUrl":"https://doi.org/10.1097/QAD.0000000000004164","url":null,"abstract":"","PeriodicalId":7502,"journal":{"name":"AIDS","volume":"39 6","pages":"766-767"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A refusal to abandon HIV science.","authors":"Abigail M Hatcher, Nicholas Metheny, K L Dunkle, Rebecca Fielding-Miller","doi":"10.1097/QAD.0000000000004188","DOIUrl":"https://doi.org/10.1097/QAD.0000000000004188","url":null,"abstract":"","PeriodicalId":7502,"journal":{"name":"AIDS","volume":"39 6","pages":"768-770"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Racial disparities in cancer risk among MSM with HIV in the United States.","authors":"Benton G Meldrum, Jennifer K McGee-Avila, Qianlai Luo, Jesse Milan, Ruth M Pfeiffer, Tyler Adamson, Tabassum Insaf, Eric A Engels, Meredith S Shiels, Cameron B Haas","doi":"10.1097/QAD.0000000000004125","DOIUrl":"10.1097/QAD.0000000000004125","url":null,"abstract":"<p><strong>Background: </strong>Greater immunosuppression is associated with an elevated risk of virus-associated cancers among people with HIV. We investigated racial and ethnic disparities in cancer risk among MSM with HIV (MSMWH).</p><p><strong>Methods: </strong>Among MSMWH from 2001 to 2019 in the HIV/AIDS Cancer Match Study, we examined Kaposi sarcoma, non-Hodgkin lymphoma (NHL), liver cancer, anal cancer, and Hodgkin lymphoma. Within racial/ethnic groups, we estimated cancer rates relative to the general population with standardized incidence ratios (SIRs). We calculated incidence rate ratios (IRRs) comparing cancer risk between racial/ethnic groups among MSMWH using Poisson regression. We stratified these calculations according to prior AIDS diagnosis to assess whether differences persisted after accounting for AIDS.</p><p><strong>Results: </strong>We evaluated 358 023 MSMWH followed for 3.2 million person-years. The SIRs for KS for Hispanic/Latino MSMWH [887; 95% confidence interval (95% CI) = 833-943] and Black MSMWH (772; 95% CI = 727-819) were higher than White MSMWH (417; 95% CI = 392-443). Among MSMWH, risk of Kaposi sarcoma was higher for Hispanic/Latino and Black MSMWH compared to White MSMWH (IRR = 1.40 and 1.24, respectively). We did not detect differences in IRRs when stratified by AIDS diagnosis. While the SIR for anal cancer was lower among Black MSMWH (24.1; 95% CI = 22.3-26.0) compared to White MSMWH (38.4; 95% CI = 36.3-40.6), incidence was not statistically different (IRR = 0.98; 95% CI = 0.89-1.08).</p><p><strong>Conclusion: </strong>Incidence rates and relative risks for several virus-related cancers were greater for Hispanic/Latino and Black MSMWH than White MSMWH, even when examined exclusively among those with or without AIDS. These disparities in cancer risk point to inequities in access to HIV care and disease burden.</p>","PeriodicalId":7502,"journal":{"name":"AIDS","volume":"39 6","pages":"728-736"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduced bone density accrual among peripubertal boys with HIV in Zimbabwe.","authors":"Lisha Jeena, Rashida A Ferrand, Victoria Simms, Cynthia Kahari, Tsitsi Bandason, Ruramayi Rukuni, Andrea M Rehman, Sarah Rowland-Jones, Anthony Y Y Hsieh, Celia L Gregson","doi":"10.1097/QAD.0000000000004134","DOIUrl":"10.1097/QAD.0000000000004134","url":null,"abstract":"<p><strong>Objective: </strong>To investigate bone density accrual over 1 year among peripubertal children with HIV (CWH) compared to children without infection (CWOH); and risk factors associated with bone density accrual among CWH.</p><p><strong>Design: </strong>A prospective cohort study in urban Zimbabwe.</p><p><strong>Methods: </strong>CWH on antiretroviral therapy aged 8-16 years, and CWOH, frequency-matched by age were recruited in Zimbabwe. Z -scores for height-adjusted total-body less-head bone mineral content for lean mass (TBLH-BMC LBM ) and size-adjusted lumbar spine bone mineral apparent density (LS-BMAD) were calculated from dual X-ray absorptiometry (DXA) scan measurements. Linear regression compared bone density accrual by HIV status.</p><p><strong>Results: </strong>Of 609 participants, 492 (80.7%) completed a follow-up visit (50.2% boys, 49.6% CWH). Mean baseline age was 12.5 years. More girl CWH than CWOH were in Tanner stages I/II at baseline. Bone density accrual (Δ) adjusted for age, Tanner stage and baseline DXA Z -score was less in boy CWH than boy CWOH {adjusted mean (95% confidence interval (CI)] ΔLS-BMAD Z -score -0.14 (-0.25 to -0.02) vs. 0.01 (-0.09 to 0.12), P  = 0.020, and ΔTBLH-BMC LBMZ -score -0.19 (-0.33 to -0.04) vs. 0.07 (-0.07 to 0.20), P  = 0.015}, but similar in girls with and without HIV [ΔLS-BMAD Z -score 0.05 (-0.07 to 0.17) vs. -0.01 (-0.09 to 0.07), P  = 0.416, and ΔTBLH-BMC LBMZ -score 0.08 (-0.07 to 0.22) vs. -0.03 (-0.12 to 0.07), P  = 0.295]. Viral load greater than 1000 copies/ml and tenofovir disoproxil fumarate use were associated with less gain in LS-BMAD Z -score among boys, whereas Tanner stage IV and V were associated with greater gains in LS-BMAD and TBLH-BMC LBMZ -scores among CWH.</p><p><strong>Conclusion: </strong>Among boys only, CWH had impaired bone accrual, associated with high viral load and tenofovir use. Bone density gains were greater in later puberty among CWH suggesting potential to correct deficits.</p>","PeriodicalId":7502,"journal":{"name":"AIDS","volume":" ","pages":"683-694"},"PeriodicalIF":3.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143254021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}