Spartan medical research journal最新文献

{"title":"Evaluating The Glasgow Blatchford Score for Upper Gastrointestinal Bleeding Risk Stratification in A Community Hospital: A Retrospective Study.","authors":"Hind H Neamah, Alexandra Davies, Anthony Teta, Grace D Brannan, Sami Abdelaziz, Bruce Kovan","doi":"10.51894/001c.137546","DOIUrl":"https://doi.org/10.51894/001c.137546","url":null,"abstract":"<p><strong>Introduction: </strong>Upper gastrointestinal bleeding (UGIB) is the most common emergency in gastroenterology. The Glasgow Blatchford Score (GBS) is a validated tool used for risk stratification. The cutoff values for GBS to predict the need for clinical intervention, endoscopic treatment, and mortality, are not consistent. To determine the relationship between mean GBS score and the need for hemostatic intervention, and blood transfusion, and to evaluate quality of care and proper allocation of resources at our midwestern community hospital.</p><p><strong>Methods: </strong>In this cross-sectional study, we retrospectively extracted records for patients ≥18 years who were admitted for UGIB and underwent esophagogastroduodenoscopy between July 2018 and July 2020. GBS was calculated for each observation. Multivariate analysis and a logistic regression model were performed to predict the GBS score, and the odds ratio, associated with the need for hemostatic intervention and blood transfusion while controlling for confounding factors.</p><p><strong>Results: </strong>The GBS sample mean score was 11.17. Those who required hemostatic intervention and blood transfusion scored significantly higher GBS (13.18 versus 10.79) and (13.57 versus 9.21), respectively. A GBS of >10 was associated with higher odds at 21.84 (CI: 10.324,46.185, P<0.001) and 5.085 (CI: 1.864, 13.872, P=0.001) for receiving blood transfusion and hemostatic intervention, respectively. A cutoff of 10 was 22.41% sensitive and 95.41% specific for requiring hemostatic interventions and 66.67% sensitive and 89.91% specific for receiving blood transfusion.</p><p><strong>Conclusion: </strong>There is a clinical role to using the GBS even at a score higher than 2 to further stratify the severity of UGIB and determine the need for intervention. The sensitivity of a score of 10 on the GBS in this dataset was low. A cutoff with higher sensitivity is needed to stratify a life-threatening condition such as UGIB.</p>","PeriodicalId":74853,"journal":{"name":"Spartan medical research journal","volume":"10 1","pages":"15-22"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of Combining a Simulation-Based Method with Lecture for Retinopathy Training in Emergency Medicine Residency.","authors":"Kevin Durell, Arlen Hooley","doi":"10.51894/001c.137284","DOIUrl":"https://doi.org/10.51894/001c.137284","url":null,"abstract":"<p><strong>Introduction: </strong>Funduscopic examination is a critical skill for diagnosing eye-related pathologies but has witnessed a decline in proficiency over recent decades. Simulation-based training is proposed as a solution to enhance emergency medicine residents' funduscopic examination skills. We hypothesized that a combination of lecture and simulation would improve residents' diagnostic abilities, with senior residents potentially outperforming junior counterparts.</p><p><strong>Methods: </strong>This study aimed to assess the effectiveness of simulation-based training in improving the funduscopic examination skills of emergency medicine residents and whether factors such as seniority or prior ophthalmology rotation influenced the results. Residents participated in a 10-question image-based exam, with alternating pairs viewing images and answering questions. Simulation equipment, including digital eye examination retinopathy trainers, was utilized for the study. A lecture covering possible answers was provided, followed by a second round of testing.</p><p><strong>Results: </strong>A total of 20 participants in this pilot study took both the pre- and post-lecture tests. Test scores significantly improved after supplemental education, indicating the effectiveness of simulation-based training in enhancing funduscopic diagnostic skills. Interestingly, resident year and prior completion of an ophthalmology rotation did not significantly impact test scores, underscoring the importance of supplemental education. Notably, participants demonstrated high accuracy in identifying Normal Fundus and several specific pathologies post-training.</p><p><strong>Conclusion: </strong>Simulation-based training, supplemented by lectures, offers a promising avenue for improving funduscopic examination proficiency among emergency medicine residents. This study's findings highlight the potential for standardized training methods to benefit residents across different levels of experience. Future research could explore the long-term retention of these skills and their translation into clinical practice. In an era where technological advancements are reshaping medical education, simulation-based training offers a promising avenue for ensuring that essential clinical skills are not lost but rather strengthened among medical professionals.</p>","PeriodicalId":74853,"journal":{"name":"Spartan medical research journal","volume":"10 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065451/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Porosities of 3D Printed Titanium Implants on the Tensile Properties: Correspondence.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.51894/001c.127958","DOIUrl":"10.51894/001c.127958","url":null,"abstract":"","PeriodicalId":74853,"journal":{"name":"Spartan medical research journal","volume":"10 1","pages":"127958"},"PeriodicalIF":0.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11717371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical predictors of hospital-acquired bloodstream infections: A healthcare system analysis.","authors":"Harjinder Singh, Radhika Sheth, Mehakmeet Bhatia, Abdullah Muhammad, Candi Bachour, David Metcalf, Vivek Kak","doi":"10.51894/001c.123414","DOIUrl":"https://doi.org/10.51894/001c.123414","url":null,"abstract":"<p><strong>Introduction: </strong>This study was performed to identify patient factors associated with hospital-acquired bloodstream infections (HABSI) to guide blood culture collection and empiric antibiotic therapy.</p><p><strong>Methods: </strong>A retrospective case-control study reviewed the medical records of 350 patients admitted to our health system from September 2017 to April 2020. The patients were 18 years and older and had at least one set of new positive non-contaminant blood cultures collected after 48 hours of admission, defined as HABSI. We developed clinical variables through a literature review associated with it. Univariate relationships between each variable and bacteremia were evaluated by chi-square test. A predictive model was developed through stepwise multivariate logistic regression.</p><p><strong>Results: </strong>The univariate analysis and stepwise regression analysis showed that temperature >100.4° F (OR: 1.9, CI 1.1 to 3.4), male sex (OR: 1.8, CI 1.0 to 3.0), and platelet count <150,000/µL (OR: 1.8, CI 1.0 to 3.2) were statistically associated with a positive blood culture.</p><p><strong>Conclusions: </strong>This model helps identify patients with clinical characteristics associated with the likelihood of HABSI. This model can help guide the appropriate initiation of empiric antibiotics in clinical situations and assist with antibiotic stewardship.</p>","PeriodicalId":74853,"journal":{"name":"Spartan medical research journal","volume":"9 3","pages":"123414"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11402462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging Innovation and Clinical Insights: Reflections on Healthcare Research and Emergency Medicine.","authors":"Francis O Akenami, Rana Ismail, Andrea Amalfitano","doi":"10.51894/001c.124544","DOIUrl":"10.51894/001c.124544","url":null,"abstract":"","PeriodicalId":74853,"journal":{"name":"Spartan medical research journal","volume":"9 3","pages":"124544"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corticosteroid Prescribing Patterns in the Emergency Department for Acute COPD Exacerbations: A Retrospective Analysis Following an Educational Intervention.","authors":"Christopher Nedzlek, Jacob Blanchett, Zachary Illg, Geoffrey DiGiacinto, Kathryn Cunningham, Samuel J Wisniewski, Jacob Tuttle","doi":"10.51894/001c.124542","DOIUrl":"10.51894/001c.124542","url":null,"abstract":"<p><strong>Introduction: </strong>COPD is a progressive lung disease with marked airflow limitation. It has a large global prevalence and is managed with antibiotics, bronchodilators, and corticosteroids. Despite the prevalence, corticosteroid prescribing regimens differ widely amongst providers. This study aims to evaluate baseline corticosteroid prescribing patterns, the ability to change corticosteroid prescribing patterns with the utilization of an educational initiative, and to evaluate the effect of corticosteroid dose on length of stay, 30-day hospital readmission, mortality, and total hospital insulin dosing.</p><p><strong>Methods: </strong>This study was conducted via a retrospective observational study. Providers at a single institution answered a baseline questionnaire on COPD corticosteroid prescribing patterns and subsequently received an educational presentation regarding evidence-based corticosteroid recommendations. Data were then retrospectively obtained and analyzed evaluating corticosteroid prescribing patterns both pre- and post-educational intervention. Data were analyzed using IBM SPSS Version 25.</p><p><strong>Results: </strong>The provider survey revealed that most (95.3%) administered 125 mg of methylprednisolone to patients treated for AECOPD. The most common reason a particular dose of corticosteroid was administered was due to previous teaching or practice patterns. The mean initial steroid dose of methylprednisolone decreased following the educational initiative from 114.24 mg to 72.8 mg (p < 0.01). This corresponded to a 69% (n=41) decrease of providers using 125 mg methylprednisolone (p < 0.01), and increased prescribing of 62.5 mg methylprednisolone by 42.6% (n=66). The mean LOS following hospital admission for AECOPD in the pre-intervention group was 5.80 days, while the mean LOS following the targeted educational intervention decreased to 4.82 days (p = 0.01).</p><p><strong>Conclusions: </strong>The implementation of an educational intervention may change provider corticosteroid prescribing patterns. Additionally, lower corticosteroid dose in the Emergency Department may decrease patient length of stay. Keywords: Corticosteroid, COPD, LOS, recommendations, steroid.</p>","PeriodicalId":74853,"journal":{"name":"Spartan medical research journal","volume":"9 3","pages":"124542"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11487341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Pharmacologic Options and Emerging Therapeutic Approaches for the Management of Ulcerative Colitis: A Narrative Review.","authors":"Sneha Annie Sebastian, Oroshay Kaiwan, Edzel L Co, Meghana Mehendale, Babu P Mohan","doi":"10.51894/001c.123397","DOIUrl":"https://doi.org/10.51894/001c.123397","url":null,"abstract":"<p><strong>Introduction: </strong>Ulcerative colitis (UC) is a chronic inflammatory bowel disorder (IBD) with periods of relapse and remission. Current advancements in clinical research have led to the development of more refined and effective medical therapy for UC.</p><p><strong>Summary of the evidence: </strong>Traditional therapeutic agents such as 5-aminosalicylates (5-ASAs), sulfasalazine (SASP), corticosteroids, and immunomodulatory drugs have remained the gold standard for decades. However, their novel formulations and dosage regimens have changed their sequences in the medical management of UC. Several other novel drugs are in the final phases of clinical development or have recently received regulatory approval designed to target specific mechanisms involved in the inflammatory cascade for UC.</p><p><strong>Conclusions: </strong>This narrative review sought to provide a comprehensive knowledge of the potential benefits of standard and emerging therapies, including novel formulations, new chemical entities, and novel therapeutic approaches in managing UC. Keywords: Ulcerative colitis, 5- Aminosalicylic acid, sulfasalazine, corticosteroids, biologics, immunomodulators, novel formulations.</p>","PeriodicalId":74853,"journal":{"name":"Spartan medical research journal","volume":"9 3","pages":"123397"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11402463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Porosities of 3D Printed Titanium Implants on the Tensile Properties in a Rat Tendon Repair Model.","authors":"Michael Fry, Weiping Ren, Therese Bou-Akl, Bin Wu, Paula Pawlitz, David C Markel","doi":"10.51894/001c.123410","DOIUrl":"10.51894/001c.123410","url":null,"abstract":"<p><strong>Background: </strong>There is a desire in orthopaedics to have soft tissue, particularly tendon, grow into metallic implants. With the introduction of three-dimensional (3D) printed porous metal implants, we hypothesized that tendons could directly attach to the implants. However, the effects of the porous metal structure on tissue growth and penetration into the pores are unknown. Using a rat model, we investigated the effect of pore size on tendon repair fixation using 3D printed titanium implants.</p><p><strong>Methods: </strong>There were three experimental groups of eight Sprague Dawley rats (n = 24) plus control (n = 3). Implants had defined pore sizes of 400µm (n = 8), 700µm (n = 8), and 1000µm (n = 8). A defect was created in the Achilles tendon and the implant positioned between cut ends and secured with suture. Specimens were harvested at twelve weeks. Half the specimens underwent mechanical testing to assess tensile load to failure. The remaining specimens were fixed and processed for hard tissue histological analysis.</p><p><strong>Results: </strong>The average load to failure was 72.6N for controls (SD 10.04), 29.95N for 400µm (SD 17.95), 55.08N for 700µm (SD 13.47), and 63.08N for 1000µm (SD 1.87). The load to failure was generally better in the larger pore sizes. The 700µm and 1000µm specimens performed similarly, while the 400µm showed significant differences vs control (p = 0.039), vs 1000µm (p = 0.010), and approached significance vs 700µm (p = 0.066). There was increasing ingrowth as pore size increased. Histology showed fibrous tendon tissue within and around the implants, with collagen fibers organized in bundles.</p><p><strong>Conclusions: </strong>Tendon repair utilizing implants with 700µm and 1000µm pores exhibited similar load to failure as controls. Using a defined pore structure at the attachment points of tendons to implants may allow predictable tendon ingrowth onto/into an implant at the time of revision arthroplasty.</p>","PeriodicalId":74853,"journal":{"name":"Spartan medical research journal","volume":"9 3","pages":"123410"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contemporary Trends in Frontal Sinus Balloon Sinuplasty: A Pilot Study.","authors":"Daniel H Lofgren, Brandon B Knight, Carl B Shermetaro","doi":"10.51894/001c.123407","DOIUrl":"https://doi.org/10.51894/001c.123407","url":null,"abstract":"<p><strong>Introduction: </strong>Balloon sinuplasty (BSP) is a common treatment modality used in the management of chronic rhinosinusitis (CRS). Although it has gained popularity, minimal self-reported data on its utilization and complications have been reported. The goal of this study was to describe current practices and complications experienced during frontal sinus BSP.</p><p><strong>Methods: </strong>An anonymous 20-question online survey was distributed to members of the American Osteopathic Colleges of Ophthalmology and Otolaryngology-Head and Neck Surgery from August 1, 2022, to August 30, 2022. The questions were listed as multiple choice or percentage sliding bars, and data were collected using a commercial online survey service site. Results were reported as frequencies, means, and percentages.</p><p><strong>Results: </strong>Forty-two respondents participated in the survey, with the majority practicing in the following hospital settings: community (34, 80.95%), hybrid (5, 11.90%), and academic (3, 7.14%). The southeast had the largest proportion of respondents (13, 30.95%), versus the midwest (12, 28.57%), southwest (10, 23.81%), northeast (5, 11.90%), and northwest (2, 4.76%). On average, 50.52% of cases were performed in the hospital setting, 48.50% in-office, and 42.40% in surgery centers. Respondents who primarily used BSP, reported a yearly average of 35.72 cases, a median of 12 cases, and a range of 0-361 cases. Respondents who used BSP with functional endoscopic sinus surgery (FESS), reported a yearly average of 48.62 cases, a median of 31 cases, and a range of 0-189 cases. Nasal packing was utilized both intraoperatively (11.72%) and postoperatively (3.62%). Early complications included postoperative headaches (9.86%), acute bacterial sinusitis (ABRS) (3.52%), and tooth/facial numbness (0.86%). Reported long-term complications included postoperative synechiae (5.10%), orbital complications (0.14%), and skull base complications (0.10%). A previously unreported complication was identified through this study, accidental sphenopalatine fossa dilation.</p><p><strong>Conclusions: </strong>This study contributes to the growing body of literature on frontal sinus BSP by characterizing utilization and complications from a large otolaryngologic academy.</p>","PeriodicalId":74853,"journal":{"name":"Spartan medical research journal","volume":"9 3","pages":"123407"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11389658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative Supine Sleeping Position Following Total Knee Arthroplasty Decreases Knee Flexion Contractures.","authors":"Robert L Zondervan, Patrick K Riggle, Adam J Cien, Philip C Penny, Jason M Cochran","doi":"10.51894/001c.123412","DOIUrl":"10.51894/001c.123412","url":null,"abstract":"<p><strong>Background: </strong>Total knee arthroplasty (TKA) is an orthopaedic operation that improves quality of life and reduces pain in patients with disabling arthritis of the knee. One commonly recognized postoperative complication is flexion contracture of the knee. While early physical therapy and range of motion (ROM) exercises have helped improve ROM postoperatively, flexion contractures still remain a significant postoperative complication of TKA.This study evaluated postoperative sleeping position and its effect on terminal knee extension and ROM following primary TKA. We hypothesized that patients who slept in the supine position would achieve earlier knee extension and ROM when compared to those in the lateral recumbent position.</p><p><strong>Methods: </strong>A total of 150 consecutive primary total knee arthroplasties (TKAs) were conducted by a single surgeon (JMC). Prospective data collection included assessments of preoperative range of motion (ROM), postoperative ROM, patient-reported outcome measures, and sleeping positions. Functional outcomes and patient-reported measures were compared between pre- and postoperative phases, as well as across different sleeping position groups.</p><p><strong>Results: </strong>Postoperative follow up was a mean of 29.6 days. Mean postoperative terminal extension ROM at one month was 2.98 degrees in the supine group versus 6.03 degrees in the lateral group (P < 0.001). Overall, there was significant improvement in patient reported outcome measures (WOMAC, Oxford, and pain) after surgery, but no difference existed between sleeping groups. For knee extension, a two-way ANOVA revealed that there was a statistically significant interaction between the effects of surgery and sleep position (p = 0.0053).</p><p><strong>Conclusions: </strong>Our results demonstrate that sleeping position does affect initial postoperative knee terminal extension; however, there is no effect on patient reported outcomes. We found a statistically significant difference in extension when comparing patients in the supine versus lateral group. Patients who slept in the lateral position lacked 6.03 degrees of extension which is greater than the 5 degrees threshold needed for normal gait mechanics. Conversely, those in the supine group only lacked 2.98 degrees of extension, allowing for normal gait mechanics. This study identifies an easy, effective means of increasing patient knee range of motion following TKA.</p>","PeriodicalId":74853,"journal":{"name":"Spartan medical research journal","volume":"9 3","pages":"35-42"},"PeriodicalIF":0.0,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11686962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}